Toxic Effects of Patulin on Sheep
- Autores
- Tapia, Maria Ofelia; Giordano, Antonio Felix Marcelo; Soraci, Alejandro Luis; González, Carlos A.; Denzoin, Laura Andrea; Ortega, Irma; Olson, William; Murphy, Michael J.
- Año de publicación
- 2006
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- The objective of this study was to evaluate the adverse effects of patulin on beef and dairy sheep. In the beef sheep trial, nine Corriedale lambs averaging 26± 3 kg-1 BW were used. The treatment group, n=5, received 3.3 mg patulin/kg-1 BW twice daily (BID) on days 0 through 2; 4.5 mg/kg-1 BW on days 3 through 5, and 5 mg/ kg-1 BW on day 6. Lambs received no patulin from day 7 through 13. The control lambs, n= 4, received an equal volume of water by stomach tube BID. The dry matter (DM) intake in dosed sheep was 22 % less than that of control animals after three days of treatment with 3.3 mg patulin/ kg-1 BW. This difference increased to 40 % as the dose of patulin increased to 5 mg/kg-1 BW. Differences in DM consumption remained significant through day 13 ( P< 0.01). After 6 days of increasing doses of patulin, the body weight of treated sheep was 89 % of that of the control animals. By the end of the trial, body weight in the patulin group was 86 % of that of the control group. The daily weight gain was lower in treated animals between days 0 to 7; and 0 to 13 (P < 0.05). In the dairy sheep trial, thirteen crossbred F1 or F2 Milkschaw x Corriedale ewes averaging 56 + 6 kg-1 BW were used. The treatment group, n= 7, received 3.3 mg patulin/kg-1 BW divided BID. The control group, n=6, received an equal volume of water by stomach tube BID. Neither changes in body weight nor effects on feed intake were observed in the patulin treated group. Effects on milk production, serum biochemistry, electrolytes, and hematology parameters were not detected. Contrary to what it was expected patulin treatment in almost equal doses shown to be effective for beef sheep failed to influence production and health in dairy sheep. Factors such as age, diet and composition of rumen microflora might have contributed to the difference in behavior.
Fil: Tapia, Maria Ofelia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina
Fil: Giordano, Antonio Felix Marcelo. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina
Fil: Soraci, Alejandro Luis. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina
Fil: González, Carlos A.. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina
Fil: Denzoin, Laura Andrea. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina
Fil: Ortega, Irma. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina
Fil: Olson, William. University of Minnesota; Estados Unidos
Fil: Murphy, Michael J.. University of Minnesota; Estados Unidos - Materia
-
PATULIN
SHEEP - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/106499
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Toxic Effects of Patulin on SheepTapia, Maria OfeliaGiordano, Antonio Felix MarceloSoraci, Alejandro LuisGonzález, Carlos A.Denzoin, Laura AndreaOrtega, IrmaOlson, WilliamMurphy, Michael J.PATULINSHEEPhttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4The objective of this study was to evaluate the adverse effects of patulin on beef and dairy sheep. In the beef sheep trial, nine Corriedale lambs averaging 26± 3 kg-1 BW were used. The treatment group, n=5, received 3.3 mg patulin/kg-1 BW twice daily (BID) on days 0 through 2; 4.5 mg/kg-1 BW on days 3 through 5, and 5 mg/ kg-1 BW on day 6. Lambs received no patulin from day 7 through 13. The control lambs, n= 4, received an equal volume of water by stomach tube BID. The dry matter (DM) intake in dosed sheep was 22 % less than that of control animals after three days of treatment with 3.3 mg patulin/ kg-1 BW. This difference increased to 40 % as the dose of patulin increased to 5 mg/kg-1 BW. Differences in DM consumption remained significant through day 13 ( P< 0.01). After 6 days of increasing doses of patulin, the body weight of treated sheep was 89 % of that of the control animals. By the end of the trial, body weight in the patulin group was 86 % of that of the control group. The daily weight gain was lower in treated animals between days 0 to 7; and 0 to 13 (P < 0.05). In the dairy sheep trial, thirteen crossbred F1 or F2 Milkschaw x Corriedale ewes averaging 56 + 6 kg-1 BW were used. The treatment group, n= 7, received 3.3 mg patulin/kg-1 BW divided BID. The control group, n=6, received an equal volume of water by stomach tube BID. Neither changes in body weight nor effects on feed intake were observed in the patulin treated group. Effects on milk production, serum biochemistry, electrolytes, and hematology parameters were not detected. Contrary to what it was expected patulin treatment in almost equal doses shown to be effective for beef sheep failed to influence production and health in dairy sheep. Factors such as age, diet and composition of rumen microflora might have contributed to the difference in behavior.Fil: Tapia, Maria Ofelia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Giordano, Antonio Felix Marcelo. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Soraci, Alejandro Luis. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: González, Carlos A.. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Denzoin, Laura Andrea. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Ortega, Irma. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Olson, William. University of Minnesota; Estados UnidosFil: Murphy, Michael J.. University of Minnesota; Estados UnidosMedwell Online2006-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/106499Tapia, Maria Ofelia; Giordano, Antonio Felix Marcelo; Soraci, Alejandro Luis; González, Carlos A.; Denzoin, Laura Andrea; et al.; Toxic Effects of Patulin on Sheep; Medwell Online; Journal of Animal and Veterinary Advances; 5; 4; 12-2006; 271-2761680-55931993-601XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://medwelljournals.com/abstract/?doi=javaa.2006.271.276info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:47:04Zoai:ri.conicet.gov.ar:11336/106499instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:47:04.279CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Toxic Effects of Patulin on Sheep |
title |
Toxic Effects of Patulin on Sheep |
spellingShingle |
Toxic Effects of Patulin on Sheep Tapia, Maria Ofelia PATULIN SHEEP |
title_short |
Toxic Effects of Patulin on Sheep |
title_full |
Toxic Effects of Patulin on Sheep |
title_fullStr |
Toxic Effects of Patulin on Sheep |
title_full_unstemmed |
Toxic Effects of Patulin on Sheep |
title_sort |
Toxic Effects of Patulin on Sheep |
dc.creator.none.fl_str_mv |
Tapia, Maria Ofelia Giordano, Antonio Felix Marcelo Soraci, Alejandro Luis González, Carlos A. Denzoin, Laura Andrea Ortega, Irma Olson, William Murphy, Michael J. |
author |
Tapia, Maria Ofelia |
author_facet |
Tapia, Maria Ofelia Giordano, Antonio Felix Marcelo Soraci, Alejandro Luis González, Carlos A. Denzoin, Laura Andrea Ortega, Irma Olson, William Murphy, Michael J. |
author_role |
author |
author2 |
Giordano, Antonio Felix Marcelo Soraci, Alejandro Luis González, Carlos A. Denzoin, Laura Andrea Ortega, Irma Olson, William Murphy, Michael J. |
author2_role |
author author author author author author author |
dc.subject.none.fl_str_mv |
PATULIN SHEEP |
topic |
PATULIN SHEEP |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/4.3 https://purl.org/becyt/ford/4 |
dc.description.none.fl_txt_mv |
The objective of this study was to evaluate the adverse effects of patulin on beef and dairy sheep. In the beef sheep trial, nine Corriedale lambs averaging 26± 3 kg-1 BW were used. The treatment group, n=5, received 3.3 mg patulin/kg-1 BW twice daily (BID) on days 0 through 2; 4.5 mg/kg-1 BW on days 3 through 5, and 5 mg/ kg-1 BW on day 6. Lambs received no patulin from day 7 through 13. The control lambs, n= 4, received an equal volume of water by stomach tube BID. The dry matter (DM) intake in dosed sheep was 22 % less than that of control animals after three days of treatment with 3.3 mg patulin/ kg-1 BW. This difference increased to 40 % as the dose of patulin increased to 5 mg/kg-1 BW. Differences in DM consumption remained significant through day 13 ( P< 0.01). After 6 days of increasing doses of patulin, the body weight of treated sheep was 89 % of that of the control animals. By the end of the trial, body weight in the patulin group was 86 % of that of the control group. The daily weight gain was lower in treated animals between days 0 to 7; and 0 to 13 (P < 0.05). In the dairy sheep trial, thirteen crossbred F1 or F2 Milkschaw x Corriedale ewes averaging 56 + 6 kg-1 BW were used. The treatment group, n= 7, received 3.3 mg patulin/kg-1 BW divided BID. The control group, n=6, received an equal volume of water by stomach tube BID. Neither changes in body weight nor effects on feed intake were observed in the patulin treated group. Effects on milk production, serum biochemistry, electrolytes, and hematology parameters were not detected. Contrary to what it was expected patulin treatment in almost equal doses shown to be effective for beef sheep failed to influence production and health in dairy sheep. Factors such as age, diet and composition of rumen microflora might have contributed to the difference in behavior. Fil: Tapia, Maria Ofelia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina Fil: Giordano, Antonio Felix Marcelo. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina Fil: Soraci, Alejandro Luis. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina Fil: González, Carlos A.. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina Fil: Denzoin, Laura Andrea. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina Fil: Ortega, Irma. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina Fil: Olson, William. University of Minnesota; Estados Unidos Fil: Murphy, Michael J.. University of Minnesota; Estados Unidos |
description |
The objective of this study was to evaluate the adverse effects of patulin on beef and dairy sheep. In the beef sheep trial, nine Corriedale lambs averaging 26± 3 kg-1 BW were used. The treatment group, n=5, received 3.3 mg patulin/kg-1 BW twice daily (BID) on days 0 through 2; 4.5 mg/kg-1 BW on days 3 through 5, and 5 mg/ kg-1 BW on day 6. Lambs received no patulin from day 7 through 13. The control lambs, n= 4, received an equal volume of water by stomach tube BID. The dry matter (DM) intake in dosed sheep was 22 % less than that of control animals after three days of treatment with 3.3 mg patulin/ kg-1 BW. This difference increased to 40 % as the dose of patulin increased to 5 mg/kg-1 BW. Differences in DM consumption remained significant through day 13 ( P< 0.01). After 6 days of increasing doses of patulin, the body weight of treated sheep was 89 % of that of the control animals. By the end of the trial, body weight in the patulin group was 86 % of that of the control group. The daily weight gain was lower in treated animals between days 0 to 7; and 0 to 13 (P < 0.05). In the dairy sheep trial, thirteen crossbred F1 or F2 Milkschaw x Corriedale ewes averaging 56 + 6 kg-1 BW were used. The treatment group, n= 7, received 3.3 mg patulin/kg-1 BW divided BID. The control group, n=6, received an equal volume of water by stomach tube BID. Neither changes in body weight nor effects on feed intake were observed in the patulin treated group. Effects on milk production, serum biochemistry, electrolytes, and hematology parameters were not detected. Contrary to what it was expected patulin treatment in almost equal doses shown to be effective for beef sheep failed to influence production and health in dairy sheep. Factors such as age, diet and composition of rumen microflora might have contributed to the difference in behavior. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-12 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/106499 Tapia, Maria Ofelia; Giordano, Antonio Felix Marcelo; Soraci, Alejandro Luis; González, Carlos A.; Denzoin, Laura Andrea; et al.; Toxic Effects of Patulin on Sheep; Medwell Online; Journal of Animal and Veterinary Advances; 5; 4; 12-2006; 271-276 1680-5593 1993-601X CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/106499 |
identifier_str_mv |
Tapia, Maria Ofelia; Giordano, Antonio Felix Marcelo; Soraci, Alejandro Luis; González, Carlos A.; Denzoin, Laura Andrea; et al.; Toxic Effects of Patulin on Sheep; Medwell Online; Journal of Animal and Veterinary Advances; 5; 4; 12-2006; 271-276 1680-5593 1993-601X CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/https://medwelljournals.com/abstract/?doi=javaa.2006.271.276 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Medwell Online |
publisher.none.fl_str_mv |
Medwell Online |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1842268834943205376 |
score |
13.13397 |