Metformin in the treatment of polycystic ovary syndrome

Autores
Motta, Alicia Beatriz
Año de publicación
2008
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Polycystic ovary syndrome (PCOS) is one of the most frequent diseases that affects women in their reproductive age. The heterogeneity of PCOS makes not only the diagnosis but also the choice of an adequate treatment difficult. The biguanide, N, N´ dimethyl-biguanide : Metformin is an antidiabetic drug that increases glucose utilization in insulin-sensitive tissues and is useful in the reduction of both insulin resistance and circulating androgens as well as restoring ovulation. However, metformin is being clinically used without a complete understanding of the mechanism involved. The present review explores some of the actions and efficacy of metformin in the treatment of PCOS during different reproductive periods.
Fil: Motta, Alicia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; Argentina
Materia
Polycystic Ovary Syndrome
Metformin
Ovulation
Infertility
Diabetes
Adolescents
Pregnancy
Cardiovascular
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/20287
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/20287
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Metformin in the treatment of polycystic ovary syndromeMotta, Alicia BeatrizPolycystic Ovary SyndromeMetforminOvulationInfertilityDiabetesAdolescentsPregnancyCardiovascularhttps://purl.org/becyt/ford/3.5https://purl.org/becyt/ford/3Polycystic ovary syndrome (PCOS) is one of the most frequent diseases that affects women in their reproductive age. The heterogeneity of PCOS makes not only the diagnosis but also the choice of an adequate treatment difficult. The biguanide, N, N´ dimethyl-biguanide : Metformin is an antidiabetic drug that increases glucose utilization in insulin-sensitive tissues and is useful in the reduction of both insulin resistance and circulating androgens as well as restoring ovulation. However, metformin is being clinically used without a complete understanding of the mechanism involved. The present review explores some of the actions and efficacy of metformin in the treatment of PCOS during different reproductive periods.Fil: Motta, Alicia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; ArgentinaBentham Science Publishers2008-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/20287Motta, Alicia Beatriz; Metformin in the treatment of polycystic ovary syndrome; Bentham Science Publishers; Current Pharmaceutical Design; 14; 21; 8-2008; 2121-21251381-61281873-4286CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.2174/138161208785294609info:eu-repo/semantics/altIdentifier/url/http://www.eurekaselect.com/67496/articleinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:04:35Zoai:ri.conicet.gov.ar:11336/20287instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:04:35.811CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Metformin in the treatment of polycystic ovary syndrome
title Metformin in the treatment of polycystic ovary syndrome
spellingShingle Metformin in the treatment of polycystic ovary syndrome
Motta, Alicia Beatriz
Polycystic Ovary Syndrome
Metformin
Ovulation
Infertility
Diabetes
Adolescents
Pregnancy
Cardiovascular
title_short Metformin in the treatment of polycystic ovary syndrome
title_full Metformin in the treatment of polycystic ovary syndrome
title_fullStr Metformin in the treatment of polycystic ovary syndrome
title_full_unstemmed Metformin in the treatment of polycystic ovary syndrome
title_sort Metformin in the treatment of polycystic ovary syndrome
dc.creator.none.fl_str_mv Motta, Alicia Beatriz
author Motta, Alicia Beatriz
author_facet Motta, Alicia Beatriz
author_role author
dc.subject.none.fl_str_mv Polycystic Ovary Syndrome
Metformin
Ovulation
Infertility
Diabetes
Adolescents
Pregnancy
Cardiovascular
topic Polycystic Ovary Syndrome
Metformin
Ovulation
Infertility
Diabetes
Adolescents
Pregnancy
Cardiovascular
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.5
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Polycystic ovary syndrome (PCOS) is one of the most frequent diseases that affects women in their reproductive age. The heterogeneity of PCOS makes not only the diagnosis but also the choice of an adequate treatment difficult. The biguanide, N, N´ dimethyl-biguanide : Metformin is an antidiabetic drug that increases glucose utilization in insulin-sensitive tissues and is useful in the reduction of both insulin resistance and circulating androgens as well as restoring ovulation. However, metformin is being clinically used without a complete understanding of the mechanism involved. The present review explores some of the actions and efficacy of metformin in the treatment of PCOS during different reproductive periods.
Fil: Motta, Alicia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; Argentina
description Polycystic ovary syndrome (PCOS) is one of the most frequent diseases that affects women in their reproductive age. The heterogeneity of PCOS makes not only the diagnosis but also the choice of an adequate treatment difficult. The biguanide, N, N´ dimethyl-biguanide : Metformin is an antidiabetic drug that increases glucose utilization in insulin-sensitive tissues and is useful in the reduction of both insulin resistance and circulating androgens as well as restoring ovulation. However, metformin is being clinically used without a complete understanding of the mechanism involved. The present review explores some of the actions and efficacy of metformin in the treatment of PCOS during different reproductive periods.
publishDate 2008
dc.date.none.fl_str_mv 2008-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/20287
Motta, Alicia Beatriz; Metformin in the treatment of polycystic ovary syndrome; Bentham Science Publishers; Current Pharmaceutical Design; 14; 21; 8-2008; 2121-2125
1381-6128
1873-4286
CONICET Digital
CONICET
url http://hdl.handle.net/11336/20287
identifier_str_mv Motta, Alicia Beatriz; Metformin in the treatment of polycystic ovary syndrome; Bentham Science Publishers; Current Pharmaceutical Design; 14; 21; 8-2008; 2121-2125
1381-6128
1873-4286
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.2174/138161208785294609
info:eu-repo/semantics/altIdentifier/url/http://www.eurekaselect.com/67496/article
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Bentham Science Publishers
publisher.none.fl_str_mv Bentham Science Publishers
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842980157783015424
score 12.993085

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