Copy Number Variation (CNV): A New Genomic Insight in Horses

Autores
Nora Laseca; Antonio Molina; Mercedes Valera; Alicia Antonini; Demyda Peyrás, Sebastián
Año de publicación
2022
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
This study aimed to contribute to our knowledge of CNVs, a type of genomic marker in equines, by producing, for the first time, a fine-scale characterization of the CNV regions (CNVRs) in the Pura Raza Española horse breed. We found not only the existence of a unique pattern of genomic regions enriched in CNVs in the PRE in comparison with the data available from other breeds but also the incidence of CNVs across the entire genome. Since these regions could affect the structure and dose of the genes involved, we also performed a gene ontology analysis which revealed that most of the genes overlapping in CNVRs were related to the olfactory pathways and immune response.
Fil: Nora Laseca. Universidad de Córdoba; España
Fil: Antonio Molina. Universidad de Córdoba; España
Fil: Mercedes Valera. Universidad de Sevilla; España
Fil: Alicia Antonini. Facultad de Ciencias Veterinarias, Universidad Nacional de la Plata; Argentina
Fil: Demyda Peyrás, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Facultad de Ciencias Veterinarias, Universidad Nacional de la Plata; Argentina
Materia
CNV
HORSES
REPRODUCTION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/186902
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Copy Number Variation (CNV): A New Genomic Insight in HorsesNora LasecaAntonio MolinaMercedes ValeraAlicia AntoniniDemyda Peyrás, SebastiánCNVHORSESREPRODUCTIONhttps://purl.org/becyt/ford/4.4https://purl.org/becyt/ford/4This study aimed to contribute to our knowledge of CNVs, a type of genomic marker in equines, by producing, for the first time, a fine-scale characterization of the CNV regions (CNVRs) in the Pura Raza Española horse breed. We found not only the existence of a unique pattern of genomic regions enriched in CNVs in the PRE in comparison with the data available from other breeds but also the incidence of CNVs across the entire genome. Since these regions could affect the structure and dose of the genes involved, we also performed a gene ontology analysis which revealed that most of the genes overlapping in CNVRs were related to the olfactory pathways and immune response.Fil: Nora Laseca. Universidad de Córdoba; EspañaFil: Antonio Molina. Universidad de Córdoba; EspañaFil: Mercedes Valera. Universidad de Sevilla; EspañaFil: Alicia Antonini. Facultad de Ciencias Veterinarias, Universidad Nacional de la Plata; ArgentinaFil: Demyda Peyrás, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Facultad de Ciencias Veterinarias, Universidad Nacional de la Plata; ArgentinaMultidisciplinary Digital Publishing Institute2022-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/186902Nora Laseca; Antonio Molina; Mercedes Valera; Alicia Antonini; Demyda Peyrás, Sebastián; Copy Number Variation (CNV): A New Genomic Insight in Horses; Multidisciplinary Digital Publishing Institute; Animals; 12; 1435; 5-2022; 1-142076-2615CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2076-2615/12/11/1435info:eu-repo/semantics/altIdentifier/url/https://doi.org/10.3390/ani12111435info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:24:14Zoai:ri.conicet.gov.ar:11336/186902instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:24:15.079CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Copy Number Variation (CNV): A New Genomic Insight in Horses
title Copy Number Variation (CNV): A New Genomic Insight in Horses
spellingShingle Copy Number Variation (CNV): A New Genomic Insight in Horses
Nora Laseca
CNV
HORSES
REPRODUCTION
title_short Copy Number Variation (CNV): A New Genomic Insight in Horses
title_full Copy Number Variation (CNV): A New Genomic Insight in Horses
title_fullStr Copy Number Variation (CNV): A New Genomic Insight in Horses
title_full_unstemmed Copy Number Variation (CNV): A New Genomic Insight in Horses
title_sort Copy Number Variation (CNV): A New Genomic Insight in Horses
dc.creator.none.fl_str_mv Nora Laseca
Antonio Molina
Mercedes Valera
Alicia Antonini
Demyda Peyrás, Sebastián
author Nora Laseca
author_facet Nora Laseca
Antonio Molina
Mercedes Valera
Alicia Antonini
Demyda Peyrás, Sebastián
author_role author
author2 Antonio Molina
Mercedes Valera
Alicia Antonini
Demyda Peyrás, Sebastián
author2_role author
author
author
author
dc.subject.none.fl_str_mv CNV
HORSES
REPRODUCTION
topic CNV
HORSES
REPRODUCTION
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.4
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv This study aimed to contribute to our knowledge of CNVs, a type of genomic marker in equines, by producing, for the first time, a fine-scale characterization of the CNV regions (CNVRs) in the Pura Raza Española horse breed. We found not only the existence of a unique pattern of genomic regions enriched in CNVs in the PRE in comparison with the data available from other breeds but also the incidence of CNVs across the entire genome. Since these regions could affect the structure and dose of the genes involved, we also performed a gene ontology analysis which revealed that most of the genes overlapping in CNVRs were related to the olfactory pathways and immune response.
Fil: Nora Laseca. Universidad de Córdoba; España
Fil: Antonio Molina. Universidad de Córdoba; España
Fil: Mercedes Valera. Universidad de Sevilla; España
Fil: Alicia Antonini. Facultad de Ciencias Veterinarias, Universidad Nacional de la Plata; Argentina
Fil: Demyda Peyrás, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Facultad de Ciencias Veterinarias, Universidad Nacional de la Plata; Argentina
description This study aimed to contribute to our knowledge of CNVs, a type of genomic marker in equines, by producing, for the first time, a fine-scale characterization of the CNV regions (CNVRs) in the Pura Raza Española horse breed. We found not only the existence of a unique pattern of genomic regions enriched in CNVs in the PRE in comparison with the data available from other breeds but also the incidence of CNVs across the entire genome. Since these regions could affect the structure and dose of the genes involved, we also performed a gene ontology analysis which revealed that most of the genes overlapping in CNVRs were related to the olfactory pathways and immune response.
publishDate 2022
dc.date.none.fl_str_mv 2022-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/186902
Nora Laseca; Antonio Molina; Mercedes Valera; Alicia Antonini; Demyda Peyrás, Sebastián; Copy Number Variation (CNV): A New Genomic Insight in Horses; Multidisciplinary Digital Publishing Institute; Animals; 12; 1435; 5-2022; 1-14
2076-2615
CONICET Digital
CONICET
url http://hdl.handle.net/11336/186902
identifier_str_mv Nora Laseca; Antonio Molina; Mercedes Valera; Alicia Antonini; Demyda Peyrás, Sebastián; Copy Number Variation (CNV): A New Genomic Insight in Horses; Multidisciplinary Digital Publishing Institute; Animals; 12; 1435; 5-2022; 1-14
2076-2615
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2076-2615/12/11/1435
info:eu-repo/semantics/altIdentifier/url/https://doi.org/10.3390/ani12111435
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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