Design of Cannabis sativa (L.) Emulsion: Characterization and Quantification of Cannabinoids and Terpenes

Autores
Cecati, Francisco Miguel; Jofre, Maria de Los Angeles; Ortega, Claudia Alicia; Cianchino, Valeria Andrea; Favier, Laura Silvina; Reta, Guillermo Federico
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The aim of this study was to design and develop emulsions with cannabidiol-rich ethanolic extract (EE) and essential oil (EO) of Cannabis sativa L. as active and coactive herbal ingredients respectively. At the same time, an analytical methodology was developed to quantify the main cannabinoids and characterize the terpenes of the essential oil. Four O/W emulsions were prepared with 1% of EE (1g EE/100 g emulsion) F1, 0.5 % of EE (0.5g EE/100 g emulsion) F2, 0.25 % of EE (0.25g EE/100 g emulsion) F3 and 0.125 % of EE (0.125 g EE/100 g emulsion) F4. The co-active ingredient (EO) was added following the same proportions as the EE. All emulsions, F1, F2, F3, y F4 were found to have acceptable physicochemical characteristics such as pH, viscosity, extensibility, stability. Respect to the organoleptic properties only F1 was no acceptable.
Fil: Cecati, Francisco Miguel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; Argentina
Fil: Jofre, Maria de Los Angeles. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Ortega, Claudia Alicia. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Cianchino, Valeria Andrea. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Favier, Laura Silvina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Reta, Guillermo Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; Argentina
Materia
Cannabis sativa
Essential Oil
Emmulsions
Cannabinoids
Terpenoids
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/265587
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/265587
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Design of Cannabis sativa (L.) Emulsion: Characterization and Quantification of Cannabinoids and TerpenesCecati, Francisco MiguelJofre, Maria de Los AngelesOrtega, Claudia AliciaCianchino, Valeria AndreaFavier, Laura SilvinaReta, Guillermo FedericoCannabis sativaEssential OilEmmulsionsCannabinoidsTerpenoidshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1The aim of this study was to design and develop emulsions with cannabidiol-rich ethanolic extract (EE) and essential oil (EO) of Cannabis sativa L. as active and coactive herbal ingredients respectively. At the same time, an analytical methodology was developed to quantify the main cannabinoids and characterize the terpenes of the essential oil. Four O/W emulsions were prepared with 1% of EE (1g EE/100 g emulsion) F1, 0.5 % of EE (0.5g EE/100 g emulsion) F2, 0.25 % of EE (0.25g EE/100 g emulsion) F3 and 0.125 % of EE (0.125 g EE/100 g emulsion) F4. The co-active ingredient (EO) was added following the same proportions as the EE. All emulsions, F1, F2, F3, y F4 were found to have acceptable physicochemical characteristics such as pH, viscosity, extensibility, stability. Respect to the organoleptic properties only F1 was no acceptable.Fil: Cecati, Francisco Miguel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; ArgentinaFil: Jofre, Maria de Los Angeles. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; ArgentinaFil: Ortega, Claudia Alicia. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; ArgentinaFil: Cianchino, Valeria Andrea. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; ArgentinaFil: Favier, Laura Silvina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; ArgentinaFil: Reta, Guillermo Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; ArgentinaActa Scientific Publications2024-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/265587Cecati, Francisco Miguel; Jofre, Maria de Los Angeles; Ortega, Claudia Alicia; Cianchino, Valeria Andrea; Favier, Laura Silvina; et al.; Design of Cannabis sativa (L.) Emulsion: Characterization and Quantification of Cannabinoids and Terpenes; Acta Scientific Publications; Acta Scientific Nutritional Health; 8; 12; 12-2024; 69-762582-1423CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://actascientific.com/ASNH/pdf/ASNH-08-1471.pdfinfo:eu-repo/semantics/altIdentifier/doi/10.31080/ASNH.2024.08.1471info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:51:20Zoai:ri.conicet.gov.ar:11336/265587instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:51:21.205CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Design of Cannabis sativa (L.) Emulsion: Characterization and Quantification of Cannabinoids and Terpenes
title Design of Cannabis sativa (L.) Emulsion: Characterization and Quantification of Cannabinoids and Terpenes
spellingShingle Design of Cannabis sativa (L.) Emulsion: Characterization and Quantification of Cannabinoids and Terpenes
Cecati, Francisco Miguel
Cannabis sativa
Essential Oil
Emmulsions
Cannabinoids
Terpenoids
title_short Design of Cannabis sativa (L.) Emulsion: Characterization and Quantification of Cannabinoids and Terpenes
title_full Design of Cannabis sativa (L.) Emulsion: Characterization and Quantification of Cannabinoids and Terpenes
title_fullStr Design of Cannabis sativa (L.) Emulsion: Characterization and Quantification of Cannabinoids and Terpenes
title_full_unstemmed Design of Cannabis sativa (L.) Emulsion: Characterization and Quantification of Cannabinoids and Terpenes
title_sort Design of Cannabis sativa (L.) Emulsion: Characterization and Quantification of Cannabinoids and Terpenes
dc.creator.none.fl_str_mv Cecati, Francisco Miguel
Jofre, Maria de Los Angeles
Ortega, Claudia Alicia
Cianchino, Valeria Andrea
Favier, Laura Silvina
Reta, Guillermo Federico
author Cecati, Francisco Miguel
author_facet Cecati, Francisco Miguel
Jofre, Maria de Los Angeles
Ortega, Claudia Alicia
Cianchino, Valeria Andrea
Favier, Laura Silvina
Reta, Guillermo Federico
author_role author
author2 Jofre, Maria de Los Angeles
Ortega, Claudia Alicia
Cianchino, Valeria Andrea
Favier, Laura Silvina
Reta, Guillermo Federico
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Cannabis sativa
Essential Oil
Emmulsions
Cannabinoids
Terpenoids
topic Cannabis sativa
Essential Oil
Emmulsions
Cannabinoids
Terpenoids
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The aim of this study was to design and develop emulsions with cannabidiol-rich ethanolic extract (EE) and essential oil (EO) of Cannabis sativa L. as active and coactive herbal ingredients respectively. At the same time, an analytical methodology was developed to quantify the main cannabinoids and characterize the terpenes of the essential oil. Four O/W emulsions were prepared with 1% of EE (1g EE/100 g emulsion) F1, 0.5 % of EE (0.5g EE/100 g emulsion) F2, 0.25 % of EE (0.25g EE/100 g emulsion) F3 and 0.125 % of EE (0.125 g EE/100 g emulsion) F4. The co-active ingredient (EO) was added following the same proportions as the EE. All emulsions, F1, F2, F3, y F4 were found to have acceptable physicochemical characteristics such as pH, viscosity, extensibility, stability. Respect to the organoleptic properties only F1 was no acceptable.
Fil: Cecati, Francisco Miguel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; Argentina
Fil: Jofre, Maria de Los Angeles. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Ortega, Claudia Alicia. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Cianchino, Valeria Andrea. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Favier, Laura Silvina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Reta, Guillermo Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; Argentina
description The aim of this study was to design and develop emulsions with cannabidiol-rich ethanolic extract (EE) and essential oil (EO) of Cannabis sativa L. as active and coactive herbal ingredients respectively. At the same time, an analytical methodology was developed to quantify the main cannabinoids and characterize the terpenes of the essential oil. Four O/W emulsions were prepared with 1% of EE (1g EE/100 g emulsion) F1, 0.5 % of EE (0.5g EE/100 g emulsion) F2, 0.25 % of EE (0.25g EE/100 g emulsion) F3 and 0.125 % of EE (0.125 g EE/100 g emulsion) F4. The co-active ingredient (EO) was added following the same proportions as the EE. All emulsions, F1, F2, F3, y F4 were found to have acceptable physicochemical characteristics such as pH, viscosity, extensibility, stability. Respect to the organoleptic properties only F1 was no acceptable.
publishDate 2024
dc.date.none.fl_str_mv 2024-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/265587
Cecati, Francisco Miguel; Jofre, Maria de Los Angeles; Ortega, Claudia Alicia; Cianchino, Valeria Andrea; Favier, Laura Silvina; et al.; Design of Cannabis sativa (L.) Emulsion: Characterization and Quantification of Cannabinoids and Terpenes; Acta Scientific Publications; Acta Scientific Nutritional Health; 8; 12; 12-2024; 69-76
2582-1423
CONICET Digital
CONICET
url http://hdl.handle.net/11336/265587
identifier_str_mv Cecati, Francisco Miguel; Jofre, Maria de Los Angeles; Ortega, Claudia Alicia; Cianchino, Valeria Andrea; Favier, Laura Silvina; et al.; Design of Cannabis sativa (L.) Emulsion: Characterization and Quantification of Cannabinoids and Terpenes; Acta Scientific Publications; Acta Scientific Nutritional Health; 8; 12; 12-2024; 69-76
2582-1423
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://actascientific.com/ASNH/pdf/ASNH-08-1471.pdf
info:eu-repo/semantics/altIdentifier/doi/10.31080/ASNH.2024.08.1471
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Acta Scientific Publications
publisher.none.fl_str_mv Acta Scientific Publications
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269089957937152
score 13.13397

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