Cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampus

Autores
Belluscio, Mariano Andres; Mizuseki, Kenji; Schmidt, Robert; Kempter, Richard; Buzsáki, György
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Neuronal oscillations allow for temporal segmentation of neuronal spikes. Interdependent oscillators can integrate multiple layers of information. We examined phase–phase coupling of theta and gamma oscillators in the CA1 region of rat hippocampus during maze exploration and rapid eye movement sleep. Hippocampal theta waves were asymmetric, and estimation of the spatial position of the animal was improved by identifying the waveform-based phase of spiking, compared to traditional methods used for phase estimation. Using the waveform-based theta phase, three distinct gamma bands were identified: slow gammaS (gammaS; 30–50 Hz), midfrequency gammaM (gammaM; 50–90 Hz), and fast gammaF (gammaF; 90–150 Hz or epsilon band). The amplitude of each sub-band was modulated by the theta phase. In addition, we found reliable phase–phase coupling between theta and both gammaS and gammaM but not gammaF oscillators. We suggest that cross-frequency phase coupling can support multiple time-scale control of neuronal spikes within and across structures.
Fil: Belluscio, Mariano Andres. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Mizuseki, Kenji. Rutgers University; Estados Unidos
Fil: Schmidt, Robert. Rutgers University; Estados Unidos
Fil: Kempter, Richard. Rutgers University; Estados Unidos
Fil: Buzsáki, György. Rutgers University; Estados Unidos
Materia
oscillation
hippocampus
theta
gamma
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/194453
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/194453
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampusBelluscio, Mariano AndresMizuseki, KenjiSchmidt, RobertKempter, RichardBuzsáki, Györgyoscillationhippocampusthetagammahttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3https://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Neuronal oscillations allow for temporal segmentation of neuronal spikes. Interdependent oscillators can integrate multiple layers of information. We examined phase–phase coupling of theta and gamma oscillators in the CA1 region of rat hippocampus during maze exploration and rapid eye movement sleep. Hippocampal theta waves were asymmetric, and estimation of the spatial position of the animal was improved by identifying the waveform-based phase of spiking, compared to traditional methods used for phase estimation. Using the waveform-based theta phase, three distinct gamma bands were identified: slow gammaS (gammaS; 30–50 Hz), midfrequency gammaM (gammaM; 50–90 Hz), and fast gammaF (gammaF; 90–150 Hz or epsilon band). The amplitude of each sub-band was modulated by the theta phase. In addition, we found reliable phase–phase coupling between theta and both gammaS and gammaM but not gammaF oscillators. We suggest that cross-frequency phase coupling can support multiple time-scale control of neuronal spikes within and across structures.Fil: Belluscio, Mariano Andres. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Mizuseki, Kenji. Rutgers University; Estados UnidosFil: Schmidt, Robert. Rutgers University; Estados UnidosFil: Kempter, Richard. Rutgers University; Estados UnidosFil: Buzsáki, György. Rutgers University; Estados UnidosSociety for Neuroscience2012-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/194453Belluscio, Mariano Andres; Mizuseki, Kenji; Schmidt, Robert; Kempter, Richard; Buzsáki, György; Cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampus; Society for Neuroscience; Journal of Neuroscience; 32; 2; 1-2012; 423-4350270-6474CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.jneurosci.org/content/32/2/423info:eu-repo/semantics/altIdentifier/doi/10.1523/JNEUROSCI.4122-11.2012info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:40:01Zoai:ri.conicet.gov.ar:11336/194453instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:40:01.96CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampus
title Cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampus
spellingShingle Cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampus
Belluscio, Mariano Andres
oscillation
hippocampus
theta
gamma
title_short Cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampus
title_full Cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampus
title_fullStr Cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampus
title_full_unstemmed Cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampus
title_sort Cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampus
dc.creator.none.fl_str_mv Belluscio, Mariano Andres
Mizuseki, Kenji
Schmidt, Robert
Kempter, Richard
Buzsáki, György
author Belluscio, Mariano Andres
author_facet Belluscio, Mariano Andres
Mizuseki, Kenji
Schmidt, Robert
Kempter, Richard
Buzsáki, György
author_role author
author2 Mizuseki, Kenji
Schmidt, Robert
Kempter, Richard
Buzsáki, György
author2_role author
author
author
author
dc.subject.none.fl_str_mv oscillation
hippocampus
theta
gamma
topic oscillation
hippocampus
theta
gamma
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Neuronal oscillations allow for temporal segmentation of neuronal spikes. Interdependent oscillators can integrate multiple layers of information. We examined phase–phase coupling of theta and gamma oscillators in the CA1 region of rat hippocampus during maze exploration and rapid eye movement sleep. Hippocampal theta waves were asymmetric, and estimation of the spatial position of the animal was improved by identifying the waveform-based phase of spiking, compared to traditional methods used for phase estimation. Using the waveform-based theta phase, three distinct gamma bands were identified: slow gammaS (gammaS; 30–50 Hz), midfrequency gammaM (gammaM; 50–90 Hz), and fast gammaF (gammaF; 90–150 Hz or epsilon band). The amplitude of each sub-band was modulated by the theta phase. In addition, we found reliable phase–phase coupling between theta and both gammaS and gammaM but not gammaF oscillators. We suggest that cross-frequency phase coupling can support multiple time-scale control of neuronal spikes within and across structures.
Fil: Belluscio, Mariano Andres. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Mizuseki, Kenji. Rutgers University; Estados Unidos
Fil: Schmidt, Robert. Rutgers University; Estados Unidos
Fil: Kempter, Richard. Rutgers University; Estados Unidos
Fil: Buzsáki, György. Rutgers University; Estados Unidos
description Neuronal oscillations allow for temporal segmentation of neuronal spikes. Interdependent oscillators can integrate multiple layers of information. We examined phase–phase coupling of theta and gamma oscillators in the CA1 region of rat hippocampus during maze exploration and rapid eye movement sleep. Hippocampal theta waves were asymmetric, and estimation of the spatial position of the animal was improved by identifying the waveform-based phase of spiking, compared to traditional methods used for phase estimation. Using the waveform-based theta phase, three distinct gamma bands were identified: slow gammaS (gammaS; 30–50 Hz), midfrequency gammaM (gammaM; 50–90 Hz), and fast gammaF (gammaF; 90–150 Hz or epsilon band). The amplitude of each sub-band was modulated by the theta phase. In addition, we found reliable phase–phase coupling between theta and both gammaS and gammaM but not gammaF oscillators. We suggest that cross-frequency phase coupling can support multiple time-scale control of neuronal spikes within and across structures.
publishDate 2012
dc.date.none.fl_str_mv 2012-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/194453
Belluscio, Mariano Andres; Mizuseki, Kenji; Schmidt, Robert; Kempter, Richard; Buzsáki, György; Cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampus; Society for Neuroscience; Journal of Neuroscience; 32; 2; 1-2012; 423-435
0270-6474
CONICET Digital
CONICET
url http://hdl.handle.net/11336/194453
identifier_str_mv Belluscio, Mariano Andres; Mizuseki, Kenji; Schmidt, Robert; Kempter, Richard; Buzsáki, György; Cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampus; Society for Neuroscience; Journal of Neuroscience; 32; 2; 1-2012; 423-435
0270-6474
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.jneurosci.org/content/32/2/423
info:eu-repo/semantics/altIdentifier/doi/10.1523/JNEUROSCI.4122-11.2012
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Society for Neuroscience
publisher.none.fl_str_mv Society for Neuroscience
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844614427143307264
score 13.069144

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