The Timing of Reward-Seeking Action Tracks Visually-Cued Theta Oscillations in Primary Visual Cortex

• Autores: Levy, Joshua M.; Zold, Camila Lidia; Namboodiri, Vijay Mohan K.; Hussain Shuler, Marshall G
• Año de publicación: 2017
• Idioma: inglés
• Tipo de recurso: artículo
• Materia: VISUAL CORTEX; THETA OSCILLATIONS; TIMING
• Institución: Consejo Nacional de Investigaciones Científicas y Técnicas

An emerging body of work challenges the view that primary visual cortex (V1) represents the visual world faithfully. Theta oscillations in the local field potential (LFP) of V1 have been found to convey temporal expectations and, specifically, to express the delay between a visual stimulus and the reward that it portends. We extend this work by showing how these oscillatory states in male, wild-type rats can even relate to the timing of a visually cued reward-seeking behavior. In particular, we show that, with training, high precision and accuracy in behavioral timing tracks the power of these oscillations and the time of action execution covaries with their duration. These LFP oscillations are also intimately related to spiking responses at the single-unit level, which themselves carry predictive timing information. Together, these observations extend our understanding of the role of cortical oscillations in timing generally and the role of V1 in the timing of visually cued behaviors specifically.
Fil: Levy, Joshua M.. University Johns Hopkins; Estados Unidos
Fil: Zold, Camila Lidia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Fisiología y Biofísica Bernardo Houssay. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Fisiología y Biofísica Bernardo Houssay; Argentina
Fil: Namboodiri, Vijay Mohan K.. University of North Carolina; Estados Unidos
Fil: Hussain Shuler, Marshall G. University Johns Hopkins; Estados Unidos