Polidextrose enhances calcium absorption and bone mineralization in ovariectomized rats

Autores
Weisstaub, Adriana; Abdala, Victoria; Gonzalez Chaves, Macarena; Mandalunis, Patricia; Zuleta, Angela; Zeni, Susana Noemi
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Purpose. To evaluate the effect of polydextrose (PDX) on Ca bioavailability and prevention of loss of bone mass. Methods. Twenty-four two-month-old ovariectomized rats were fed three isocaloric diets only varied in fiber source and content up to 60 days (FOS group, a commercial mixture of short- and long-chain fructooligosaccharide, OVX group fed AIN 93 diet, and PDX group). A SHAM group was included as control. Apparent Ca absorption percentage (%ABS), changes in total skeleton bone mineral content (tsBMC) and bone mineral density (BMD) and femur BMD, % Bone Volume, Ca and organic femur content, caecal weight, and pH were evaluated. Results. %ABS and caecum weight of PDX and FOS were higher, and caecum pH was lower compared to OVX and SHAM. PDX reached a higher pH and lower caecum weight than FOS possibly because PDX is not completely fermented in the colon. Changes in tsBMC and femur BMD in FOS and PDX were significant lower than SHAM but significantly higher than OVX. % Bone Volume and femur % of Ca in PDX were significantly higher than OVX and FOS but lower than SHAM. Conclusions. PDX increased Ca absorption and prevented bone loss in OVX rats.
Fil: Weisstaub, Adriana. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Abdala, Victoria. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Gonzalez Chaves, Macarena. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo; Argentina
Fil: Mandalunis, Patricia. Universidad de Buenos Aires. Facultad de Odontología; Argentina
Fil: Zuleta, Angela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Zeni, Susana Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo; Argentina
Materia
Polidextrosa
Prebioticos
Calcium
Bone mass
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/6599
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/6599
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Polidextrose enhances calcium absorption and bone mineralization in ovariectomized ratsWeisstaub, AdrianaAbdala, VictoriaGonzalez Chaves, MacarenaMandalunis, PatriciaZuleta, AngelaZeni, Susana NoemiPolidextrosaPrebioticosCalciumBone masshttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Purpose. To evaluate the effect of polydextrose (PDX) on Ca bioavailability and prevention of loss of bone mass. Methods. Twenty-four two-month-old ovariectomized rats were fed three isocaloric diets only varied in fiber source and content up to 60 days (FOS group, a commercial mixture of short- and long-chain fructooligosaccharide, OVX group fed AIN 93 diet, and PDX group). A SHAM group was included as control. Apparent Ca absorption percentage (%ABS), changes in total skeleton bone mineral content (tsBMC) and bone mineral density (BMD) and femur BMD, % Bone Volume, Ca and organic femur content, caecal weight, and pH were evaluated. Results. %ABS and caecum weight of PDX and FOS were higher, and caecum pH was lower compared to OVX and SHAM. PDX reached a higher pH and lower caecum weight than FOS possibly because PDX is not completely fermented in the colon. Changes in tsBMC and femur BMD in FOS and PDX were significant lower than SHAM but significantly higher than OVX. % Bone Volume and femur % of Ca in PDX were significantly higher than OVX and FOS but lower than SHAM. Conclusions. PDX increased Ca absorption and prevented bone loss in OVX rats.Fil: Weisstaub, Adriana. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Abdala, Victoria. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Gonzalez Chaves, Macarena. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo; ArgentinaFil: Mandalunis, Patricia. Universidad de Buenos Aires. Facultad de Odontología; ArgentinaFil: Zuleta, Angela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Zeni, Susana Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo; ArgentinaHindawi Publishing Corporation2013-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/6599Weisstaub, Adriana; Abdala, Victoria; Gonzalez Chaves, Macarena; Mandalunis, Patricia; Zuleta, Angela; et al.; Polidextrose enhances calcium absorption and bone mineralization in ovariectomized rats; Hindawi Publishing Corporation; International Journal Of Food Sciences And Nutrition; 2013; 5-2013; 1-80963-7486enginfo:eu-repo/semantics/altIdentifier/doi/info:eu-repo/semantics/altIdentifier/doi/10.1155/2013/450794info:eu-repo/semantics/altIdentifier/url/http://www.hindawi.com/journals/ijfs/2013/450794/info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:06:46Zoai:ri.conicet.gov.ar:11336/6599instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:06:47.061CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Polidextrose enhances calcium absorption and bone mineralization in ovariectomized rats
title Polidextrose enhances calcium absorption and bone mineralization in ovariectomized rats
spellingShingle Polidextrose enhances calcium absorption and bone mineralization in ovariectomized rats
Weisstaub, Adriana
Polidextrosa
Prebioticos
Calcium
Bone mass
title_short Polidextrose enhances calcium absorption and bone mineralization in ovariectomized rats
title_full Polidextrose enhances calcium absorption and bone mineralization in ovariectomized rats
title_fullStr Polidextrose enhances calcium absorption and bone mineralization in ovariectomized rats
title_full_unstemmed Polidextrose enhances calcium absorption and bone mineralization in ovariectomized rats
title_sort Polidextrose enhances calcium absorption and bone mineralization in ovariectomized rats
dc.creator.none.fl_str_mv Weisstaub, Adriana
Abdala, Victoria
Gonzalez Chaves, Macarena
Mandalunis, Patricia
Zuleta, Angela
Zeni, Susana Noemi
author Weisstaub, Adriana
author_facet Weisstaub, Adriana
Abdala, Victoria
Gonzalez Chaves, Macarena
Mandalunis, Patricia
Zuleta, Angela
Zeni, Susana Noemi
author_role author
author2 Abdala, Victoria
Gonzalez Chaves, Macarena
Mandalunis, Patricia
Zuleta, Angela
Zeni, Susana Noemi
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Polidextrosa
Prebioticos
Calcium
Bone mass
topic Polidextrosa
Prebioticos
Calcium
Bone mass
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Purpose. To evaluate the effect of polydextrose (PDX) on Ca bioavailability and prevention of loss of bone mass. Methods. Twenty-four two-month-old ovariectomized rats were fed three isocaloric diets only varied in fiber source and content up to 60 days (FOS group, a commercial mixture of short- and long-chain fructooligosaccharide, OVX group fed AIN 93 diet, and PDX group). A SHAM group was included as control. Apparent Ca absorption percentage (%ABS), changes in total skeleton bone mineral content (tsBMC) and bone mineral density (BMD) and femur BMD, % Bone Volume, Ca and organic femur content, caecal weight, and pH were evaluated. Results. %ABS and caecum weight of PDX and FOS were higher, and caecum pH was lower compared to OVX and SHAM. PDX reached a higher pH and lower caecum weight than FOS possibly because PDX is not completely fermented in the colon. Changes in tsBMC and femur BMD in FOS and PDX were significant lower than SHAM but significantly higher than OVX. % Bone Volume and femur % of Ca in PDX were significantly higher than OVX and FOS but lower than SHAM. Conclusions. PDX increased Ca absorption and prevented bone loss in OVX rats.
Fil: Weisstaub, Adriana. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Abdala, Victoria. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Gonzalez Chaves, Macarena. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo; Argentina
Fil: Mandalunis, Patricia. Universidad de Buenos Aires. Facultad de Odontología; Argentina
Fil: Zuleta, Angela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Zeni, Susana Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo; Argentina
description Purpose. To evaluate the effect of polydextrose (PDX) on Ca bioavailability and prevention of loss of bone mass. Methods. Twenty-four two-month-old ovariectomized rats were fed three isocaloric diets only varied in fiber source and content up to 60 days (FOS group, a commercial mixture of short- and long-chain fructooligosaccharide, OVX group fed AIN 93 diet, and PDX group). A SHAM group was included as control. Apparent Ca absorption percentage (%ABS), changes in total skeleton bone mineral content (tsBMC) and bone mineral density (BMD) and femur BMD, % Bone Volume, Ca and organic femur content, caecal weight, and pH were evaluated. Results. %ABS and caecum weight of PDX and FOS were higher, and caecum pH was lower compared to OVX and SHAM. PDX reached a higher pH and lower caecum weight than FOS possibly because PDX is not completely fermented in the colon. Changes in tsBMC and femur BMD in FOS and PDX were significant lower than SHAM but significantly higher than OVX. % Bone Volume and femur % of Ca in PDX were significantly higher than OVX and FOS but lower than SHAM. Conclusions. PDX increased Ca absorption and prevented bone loss in OVX rats.
publishDate 2013
dc.date.none.fl_str_mv 2013-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/6599
Weisstaub, Adriana; Abdala, Victoria; Gonzalez Chaves, Macarena; Mandalunis, Patricia; Zuleta, Angela; et al.; Polidextrose enhances calcium absorption and bone mineralization in ovariectomized rats; Hindawi Publishing Corporation; International Journal Of Food Sciences And Nutrition; 2013; 5-2013; 1-8
0963-7486
url http://hdl.handle.net/11336/6599
identifier_str_mv Weisstaub, Adriana; Abdala, Victoria; Gonzalez Chaves, Macarena; Mandalunis, Patricia; Zuleta, Angela; et al.; Polidextrose enhances calcium absorption and bone mineralization in ovariectomized rats; Hindawi Publishing Corporation; International Journal Of Food Sciences And Nutrition; 2013; 5-2013; 1-8
0963-7486
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/
info:eu-repo/semantics/altIdentifier/doi/10.1155/2013/450794
info:eu-repo/semantics/altIdentifier/url/http://www.hindawi.com/journals/ijfs/2013/450794/
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Hindawi Publishing Corporation
publisher.none.fl_str_mv Hindawi Publishing Corporation
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269973962031104
score 12.885934

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