Epithelial Fluid Transport is Due to Electro-osmosis (80%), Plus Osmosis (20%)

Autores
Fischbarg, Jorge; Hernandez, Julio A.; Rubashkin, Andrey A.; Iserovich, Pavel; Cacace, Verónica Inés; Kusnier, Carlos Federico
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Epithelial fluid transport, an important physiological process shrouded in a long-standing enigma, may finally be moving closer to a solution. We propose that, for the corneal endothelium, relative proportions for the driving forces for fluid transport are 80% of paracellular electro-osmosis, and 20% classical transcellular osmosis. These operate in a cyclical process with a period of 9.2 s, which is dictated by the decrease and exhaustion of cellular Na+. Paracellular electro-osmosis is sketched here, and partially discussed as much as the subject still allows; transcellular osmosis is presented at length.
Fil: Fischbarg, Jorge. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
Fil: Hernandez, Julio A.. Universidad de la República; Uruguay
Fil: Rubashkin, Andrey A.. Russian Academy of Science; Rusia
Fil: Iserovich, Pavel. State University of New York; Estados Unidos
Fil: Cacace, Verónica Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
Fil: Kusnier, Carlos Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
Materia
ELECTRO-OSMOSIS
FLUID TRANSPORT
OSMOSIS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/59160
Acceder
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spelling Epithelial Fluid Transport is Due to Electro-osmosis (80%), Plus Osmosis (20%)Fischbarg, JorgeHernandez, Julio A.Rubashkin, Andrey A.Iserovich, PavelCacace, Verónica InésKusnier, Carlos FedericoELECTRO-OSMOSISFLUID TRANSPORTOSMOSIShttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Epithelial fluid transport, an important physiological process shrouded in a long-standing enigma, may finally be moving closer to a solution. We propose that, for the corneal endothelium, relative proportions for the driving forces for fluid transport are 80% of paracellular electro-osmosis, and 20% classical transcellular osmosis. These operate in a cyclical process with a period of 9.2 s, which is dictated by the decrease and exhaustion of cellular Na+. Paracellular electro-osmosis is sketched here, and partially discussed as much as the subject still allows; transcellular osmosis is presented at length.Fil: Fischbarg, Jorge. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; ArgentinaFil: Hernandez, Julio A.. Universidad de la República; UruguayFil: Rubashkin, Andrey A.. Russian Academy of Science; RusiaFil: Iserovich, Pavel. State University of New York; Estados UnidosFil: Cacace, Verónica Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; ArgentinaFil: Kusnier, Carlos Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; ArgentinaSpringer2017-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/59160Fischbarg, Jorge; Hernandez, Julio A.; Rubashkin, Andrey A.; Iserovich, Pavel; Cacace, Verónica Inés; et al.; Epithelial Fluid Transport is Due to Electro-osmosis (80%), Plus Osmosis (20%); Springer; Journal of Membrane Biology; 250; 3; 6-2017; 327-3330022-26311432-1424CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1007/s00232-017-9966-xinfo:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs00232-017-9966-xinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:30:14Zoai:ri.conicet.gov.ar:11336/59160instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:30:14.345CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Epithelial Fluid Transport is Due to Electro-osmosis (80%), Plus Osmosis (20%)
title Epithelial Fluid Transport is Due to Electro-osmosis (80%), Plus Osmosis (20%)
spellingShingle Epithelial Fluid Transport is Due to Electro-osmosis (80%), Plus Osmosis (20%)
Fischbarg, Jorge
ELECTRO-OSMOSIS
FLUID TRANSPORT
OSMOSIS
title_short Epithelial Fluid Transport is Due to Electro-osmosis (80%), Plus Osmosis (20%)
title_full Epithelial Fluid Transport is Due to Electro-osmosis (80%), Plus Osmosis (20%)
title_fullStr Epithelial Fluid Transport is Due to Electro-osmosis (80%), Plus Osmosis (20%)
title_full_unstemmed Epithelial Fluid Transport is Due to Electro-osmosis (80%), Plus Osmosis (20%)
title_sort Epithelial Fluid Transport is Due to Electro-osmosis (80%), Plus Osmosis (20%)
dc.creator.none.fl_str_mv Fischbarg, Jorge
Hernandez, Julio A.
Rubashkin, Andrey A.
Iserovich, Pavel
Cacace, Verónica Inés
Kusnier, Carlos Federico
author Fischbarg, Jorge
author_facet Fischbarg, Jorge
Hernandez, Julio A.
Rubashkin, Andrey A.
Iserovich, Pavel
Cacace, Verónica Inés
Kusnier, Carlos Federico
author_role author
author2 Hernandez, Julio A.
Rubashkin, Andrey A.
Iserovich, Pavel
Cacace, Verónica Inés
Kusnier, Carlos Federico
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv ELECTRO-OSMOSIS
FLUID TRANSPORT
OSMOSIS
topic ELECTRO-OSMOSIS
FLUID TRANSPORT
OSMOSIS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Epithelial fluid transport, an important physiological process shrouded in a long-standing enigma, may finally be moving closer to a solution. We propose that, for the corneal endothelium, relative proportions for the driving forces for fluid transport are 80% of paracellular electro-osmosis, and 20% classical transcellular osmosis. These operate in a cyclical process with a period of 9.2 s, which is dictated by the decrease and exhaustion of cellular Na+. Paracellular electro-osmosis is sketched here, and partially discussed as much as the subject still allows; transcellular osmosis is presented at length.
Fil: Fischbarg, Jorge. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
Fil: Hernandez, Julio A.. Universidad de la República; Uruguay
Fil: Rubashkin, Andrey A.. Russian Academy of Science; Rusia
Fil: Iserovich, Pavel. State University of New York; Estados Unidos
Fil: Cacace, Verónica Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
Fil: Kusnier, Carlos Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
description Epithelial fluid transport, an important physiological process shrouded in a long-standing enigma, may finally be moving closer to a solution. We propose that, for the corneal endothelium, relative proportions for the driving forces for fluid transport are 80% of paracellular electro-osmosis, and 20% classical transcellular osmosis. These operate in a cyclical process with a period of 9.2 s, which is dictated by the decrease and exhaustion of cellular Na+. Paracellular electro-osmosis is sketched here, and partially discussed as much as the subject still allows; transcellular osmosis is presented at length.
publishDate 2017
dc.date.none.fl_str_mv 2017-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/59160
Fischbarg, Jorge; Hernandez, Julio A.; Rubashkin, Andrey A.; Iserovich, Pavel; Cacace, Verónica Inés; et al.; Epithelial Fluid Transport is Due to Electro-osmosis (80%), Plus Osmosis (20%); Springer; Journal of Membrane Biology; 250; 3; 6-2017; 327-333
0022-2631
1432-1424
CONICET Digital
CONICET
url http://hdl.handle.net/11336/59160
identifier_str_mv Fischbarg, Jorge; Hernandez, Julio A.; Rubashkin, Andrey A.; Iserovich, Pavel; Cacace, Verónica Inés; et al.; Epithelial Fluid Transport is Due to Electro-osmosis (80%), Plus Osmosis (20%); Springer; Journal of Membrane Biology; 250; 3; 6-2017; 327-333
0022-2631
1432-1424
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1007/s00232-017-9966-x
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs00232-017-9966-x
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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