Phylogeographic analysis of the 2000-2002 foot-and-mouth disease epidemic in Argentina

Autores
Brito Rodriguez, Barbara Patricia; König, Guido Alberto; Cabanne, Gustavo Sebastián; Pérez Beascoechea, Claudia; Rodriguez, Luis Carlos; Perez, Andres
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Foot-and-mouth disease (FMD) is a highly transmissible disease of hooved livestock. Although FMD has been eradicated from many countries, economic and social consequences of FMD reintroductions are devastating. After achieving disease eradication, Argentina was affected by a major epidemic in 2000-2002, and within few months, FMD virus spread throughout most of the country and affected >2500 herds. Available records and viral strains allowed us to assess the origins, spread and progression of this FMD epidemic, which remained uncertain. We used whole genome viral sequences and a continuous phylogeographic diffusion approach, which revealed that the viruses that caused the outbreaks spread fast in different directions from a central area in Argentina. The analysis also suggests that the virus that caused the outbreaks in the year 2000 was different from those found during the 2001 epidemic. To estimate if the approximate overall genetic diversity of the virus was related to disease transmission, we reconstructed the viral demographic variation in time using Bayesian Skygrid approach and compared it with the epidemic curve and the within-herd transmission rate and showed that the genetic temporal diversity of the virus was associated with the increasing number of outbreaks in the exponential phase of the epidemic. Results here provide new evidence of how the disease entered and spread throughout the country. We further demonstrate that genetic data collected during a FMD epidemic can be informative indicators of the progression of an ongoing epidemic.
Fil: Brito Rodriguez, Barbara Patricia. United States Department of Agriculture. Agricultural Research Service; Argentina. Universidad de Chile; Chile
Fil: König, Guido Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales "Bernardino Rivadavia"; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Biotecnología; Argentina
Fil: Cabanne, Gustavo Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales "Bernardino Rivadavia"; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Biotecnología; Argentina
Fil: Pérez Beascoechea, Claudia. Ministerio de Agricultura, Ganadería, Pesca y Alimento. Servicio Nacional de Sanidad y Calidad Agroalimentaria; Argentina
Fil: Rodriguez, Luis Carlos. United States Department of Agriculture. Agricultural Research Service; Argentina
Fil: Perez, Andres. University of Minnesota; Estados Unidos
Materia
Virus
Argentina
Foot-And-Mouth Disease
Molecular Epidemiology
Phylogeography
Viral Transmission
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/48237
Acceder
id CONICETDig_a03d7df11f35f62cde919e24505e5360
oai_identifier_str oai:ri.conicet.gov.ar:11336/48237
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Phylogeographic analysis of the 2000-2002 foot-and-mouth disease epidemic in ArgentinaBrito Rodriguez, Barbara PatriciaKönig, Guido AlbertoCabanne, Gustavo SebastiánPérez Beascoechea, ClaudiaRodriguez, Luis CarlosPerez, AndresVirusArgentinaFoot-And-Mouth DiseaseMolecular EpidemiologyPhylogeographyViral Transmissionhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Foot-and-mouth disease (FMD) is a highly transmissible disease of hooved livestock. Although FMD has been eradicated from many countries, economic and social consequences of FMD reintroductions are devastating. After achieving disease eradication, Argentina was affected by a major epidemic in 2000-2002, and within few months, FMD virus spread throughout most of the country and affected >2500 herds. Available records and viral strains allowed us to assess the origins, spread and progression of this FMD epidemic, which remained uncertain. We used whole genome viral sequences and a continuous phylogeographic diffusion approach, which revealed that the viruses that caused the outbreaks spread fast in different directions from a central area in Argentina. The analysis also suggests that the virus that caused the outbreaks in the year 2000 was different from those found during the 2001 epidemic. To estimate if the approximate overall genetic diversity of the virus was related to disease transmission, we reconstructed the viral demographic variation in time using Bayesian Skygrid approach and compared it with the epidemic curve and the within-herd transmission rate and showed that the genetic temporal diversity of the virus was associated with the increasing number of outbreaks in the exponential phase of the epidemic. Results here provide new evidence of how the disease entered and spread throughout the country. We further demonstrate that genetic data collected during a FMD epidemic can be informative indicators of the progression of an ongoing epidemic.Fil: Brito Rodriguez, Barbara Patricia. United States Department of Agriculture. Agricultural Research Service; Argentina. Universidad de Chile; ChileFil: König, Guido Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales "Bernardino Rivadavia"; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Biotecnología; ArgentinaFil: Cabanne, Gustavo Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales "Bernardino Rivadavia"; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Biotecnología; ArgentinaFil: Pérez Beascoechea, Claudia. Ministerio de Agricultura, Ganadería, Pesca y Alimento. Servicio Nacional de Sanidad y Calidad Agroalimentaria; ArgentinaFil: Rodriguez, Luis Carlos. United States Department of Agriculture. Agricultural Research Service; ArgentinaFil: Perez, Andres. University of Minnesota; Estados UnidosElsevier Science2016-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/48237Brito Rodriguez, Barbara Patricia; König, Guido Alberto; Cabanne, Gustavo Sebastián; Pérez Beascoechea, Claudia; Rodriguez, Luis Carlos; et al.; Phylogeographic analysis of the 2000-2002 foot-and-mouth disease epidemic in Argentina; Elsevier Science; Infection, Genetics and Evolution; 41; 7-2016; 93-991567-13481567-7257CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.meegid.2016.03.026info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1567134816301071info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-11-05T09:48:37Zoai:ri.conicet.gov.ar:11336/48237instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-11-05 09:48:37.507CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Phylogeographic analysis of the 2000-2002 foot-and-mouth disease epidemic in Argentina
title Phylogeographic analysis of the 2000-2002 foot-and-mouth disease epidemic in Argentina
spellingShingle Phylogeographic analysis of the 2000-2002 foot-and-mouth disease epidemic in Argentina
Brito Rodriguez, Barbara Patricia
Virus
Argentina
Foot-And-Mouth Disease
Molecular Epidemiology
Phylogeography
Viral Transmission
title_short Phylogeographic analysis of the 2000-2002 foot-and-mouth disease epidemic in Argentina
title_full Phylogeographic analysis of the 2000-2002 foot-and-mouth disease epidemic in Argentina
title_fullStr Phylogeographic analysis of the 2000-2002 foot-and-mouth disease epidemic in Argentina
title_full_unstemmed Phylogeographic analysis of the 2000-2002 foot-and-mouth disease epidemic in Argentina
title_sort Phylogeographic analysis of the 2000-2002 foot-and-mouth disease epidemic in Argentina
dc.creator.none.fl_str_mv Brito Rodriguez, Barbara Patricia
König, Guido Alberto
Cabanne, Gustavo Sebastián
Pérez Beascoechea, Claudia
Rodriguez, Luis Carlos
Perez, Andres
author Brito Rodriguez, Barbara Patricia
author_facet Brito Rodriguez, Barbara Patricia
König, Guido Alberto
Cabanne, Gustavo Sebastián
Pérez Beascoechea, Claudia
Rodriguez, Luis Carlos
Perez, Andres
author_role author
author2 König, Guido Alberto
Cabanne, Gustavo Sebastián
Pérez Beascoechea, Claudia
Rodriguez, Luis Carlos
Perez, Andres
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Virus
Argentina
Foot-And-Mouth Disease
Molecular Epidemiology
Phylogeography
Viral Transmission
topic Virus
Argentina
Foot-And-Mouth Disease
Molecular Epidemiology
Phylogeography
Viral Transmission
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Foot-and-mouth disease (FMD) is a highly transmissible disease of hooved livestock. Although FMD has been eradicated from many countries, economic and social consequences of FMD reintroductions are devastating. After achieving disease eradication, Argentina was affected by a major epidemic in 2000-2002, and within few months, FMD virus spread throughout most of the country and affected >2500 herds. Available records and viral strains allowed us to assess the origins, spread and progression of this FMD epidemic, which remained uncertain. We used whole genome viral sequences and a continuous phylogeographic diffusion approach, which revealed that the viruses that caused the outbreaks spread fast in different directions from a central area in Argentina. The analysis also suggests that the virus that caused the outbreaks in the year 2000 was different from those found during the 2001 epidemic. To estimate if the approximate overall genetic diversity of the virus was related to disease transmission, we reconstructed the viral demographic variation in time using Bayesian Skygrid approach and compared it with the epidemic curve and the within-herd transmission rate and showed that the genetic temporal diversity of the virus was associated with the increasing number of outbreaks in the exponential phase of the epidemic. Results here provide new evidence of how the disease entered and spread throughout the country. We further demonstrate that genetic data collected during a FMD epidemic can be informative indicators of the progression of an ongoing epidemic.
Fil: Brito Rodriguez, Barbara Patricia. United States Department of Agriculture. Agricultural Research Service; Argentina. Universidad de Chile; Chile
Fil: König, Guido Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales "Bernardino Rivadavia"; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Biotecnología; Argentina
Fil: Cabanne, Gustavo Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales "Bernardino Rivadavia"; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Biotecnología; Argentina
Fil: Pérez Beascoechea, Claudia. Ministerio de Agricultura, Ganadería, Pesca y Alimento. Servicio Nacional de Sanidad y Calidad Agroalimentaria; Argentina
Fil: Rodriguez, Luis Carlos. United States Department of Agriculture. Agricultural Research Service; Argentina
Fil: Perez, Andres. University of Minnesota; Estados Unidos
description Foot-and-mouth disease (FMD) is a highly transmissible disease of hooved livestock. Although FMD has been eradicated from many countries, economic and social consequences of FMD reintroductions are devastating. After achieving disease eradication, Argentina was affected by a major epidemic in 2000-2002, and within few months, FMD virus spread throughout most of the country and affected >2500 herds. Available records and viral strains allowed us to assess the origins, spread and progression of this FMD epidemic, which remained uncertain. We used whole genome viral sequences and a continuous phylogeographic diffusion approach, which revealed that the viruses that caused the outbreaks spread fast in different directions from a central area in Argentina. The analysis also suggests that the virus that caused the outbreaks in the year 2000 was different from those found during the 2001 epidemic. To estimate if the approximate overall genetic diversity of the virus was related to disease transmission, we reconstructed the viral demographic variation in time using Bayesian Skygrid approach and compared it with the epidemic curve and the within-herd transmission rate and showed that the genetic temporal diversity of the virus was associated with the increasing number of outbreaks in the exponential phase of the epidemic. Results here provide new evidence of how the disease entered and spread throughout the country. We further demonstrate that genetic data collected during a FMD epidemic can be informative indicators of the progression of an ongoing epidemic.
publishDate 2016
dc.date.none.fl_str_mv 2016-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/48237
Brito Rodriguez, Barbara Patricia; König, Guido Alberto; Cabanne, Gustavo Sebastián; Pérez Beascoechea, Claudia; Rodriguez, Luis Carlos; et al.; Phylogeographic analysis of the 2000-2002 foot-and-mouth disease epidemic in Argentina; Elsevier Science; Infection, Genetics and Evolution; 41; 7-2016; 93-99
1567-1348
1567-7257
CONICET Digital
CONICET
url http://hdl.handle.net/11336/48237
identifier_str_mv Brito Rodriguez, Barbara Patricia; König, Guido Alberto; Cabanne, Gustavo Sebastián; Pérez Beascoechea, Claudia; Rodriguez, Luis Carlos; et al.; Phylogeographic analysis of the 2000-2002 foot-and-mouth disease epidemic in Argentina; Elsevier Science; Infection, Genetics and Evolution; 41; 7-2016; 93-99
1567-1348
1567-7257
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.meegid.2016.03.026
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1567134816301071
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1847977170064900096
score 13.082534

Publicaciones similares