Factors Associated With Within-Herd Transmission of Serotype A Foot-and-Mouth Disease Virus in Cattle, During the 2001 Outbreak in Argentina: A Protective Effect of Vaccination

Autores
Brito, B. P.; Perez, Andres Maximiliano; Cosentino, B.; Rodriguez, L. L.; König, Guido Alberto
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Argentina suffered an extensive foot-and-mouth disease (FMD) epidemic between July 2000 and January 2002, 3months after obtaining the official FMD-free without vaccination status conferred by the World Organization for Animal Health. This is one of the largest FMD epidemics controlled by implementation of a systematic mass vaccination campaign in an FMD-free country. In 2000, 124 herds were reported as FMD positive, 2394 herds in 2001 and one in January 2002; the total number of cattle herds in the country at that time was approximately 230000. Estimates of FMD transmission are important to understand the dynamics of disease spread and for estimating the value for the parameterization of disease transmission models, with the ultimate goals of predicting its spread, assessing and designing control strategies, conducting economic analyses and supporting the decision-making process. In this study, the within-herd coefficient of transmission, β, was computed for herds affected in the 2001 FMD epidemic and categorized as low or high based on the median value of β. A logistic regression model was fitted to identify factors significantly associated with high values of β. Results suggested that the odds of having a high within-herd transmission were significantly associated with time from initial herd infection to disease detection, date of report, vaccination, and time from initial herd infection to herd vaccination. Results presented in this study demonstrate, in quantifiable terms, the protective impact of vaccination in reducing FMD transmission in infected herds. These results will be useful for the parameterization of epidemiological models aimed at quantifying the impact of vaccination and for the design and implementation of FMD emergency vaccination strategies in face of an epidemic.
Fil: Brito, B. P.. University of California at Davis; Estados Unidos. Universidad Nacional de Rosario; Argentina
Fil: Perez, Andres Maximiliano. University of California at Davis; Estados Unidos. Universidad Nacional de Rosario; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Cosentino, B.. Ministerio de Agricultura, Ganadería, Pesca y Alimento. Servicio Nacional de Sanidad y Calidad Agroalimentaria; Argentina
Fil: Rodriguez, L. L.. No especifíca;
Fil: König, Guido Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Biotecnología; Argentina
Materia
FOOT-AND-MOUTH DISEASE
MODELLING
VACCINATION
WITHIN-HERD TRANSMISSION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/189167
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/189167
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Factors Associated With Within-Herd Transmission of Serotype A Foot-and-Mouth Disease Virus in Cattle, During the 2001 Outbreak in Argentina: A Protective Effect of VaccinationBrito, B. P.Perez, Andres MaximilianoCosentino, B.Rodriguez, L. L.König, Guido AlbertoFOOT-AND-MOUTH DISEASEMODELLINGVACCINATIONWITHIN-HERD TRANSMISSIONhttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Argentina suffered an extensive foot-and-mouth disease (FMD) epidemic between July 2000 and January 2002, 3months after obtaining the official FMD-free without vaccination status conferred by the World Organization for Animal Health. This is one of the largest FMD epidemics controlled by implementation of a systematic mass vaccination campaign in an FMD-free country. In 2000, 124 herds were reported as FMD positive, 2394 herds in 2001 and one in January 2002; the total number of cattle herds in the country at that time was approximately 230000. Estimates of FMD transmission are important to understand the dynamics of disease spread and for estimating the value for the parameterization of disease transmission models, with the ultimate goals of predicting its spread, assessing and designing control strategies, conducting economic analyses and supporting the decision-making process. In this study, the within-herd coefficient of transmission, β, was computed for herds affected in the 2001 FMD epidemic and categorized as low or high based on the median value of β. A logistic regression model was fitted to identify factors significantly associated with high values of β. Results suggested that the odds of having a high within-herd transmission were significantly associated with time from initial herd infection to disease detection, date of report, vaccination, and time from initial herd infection to herd vaccination. Results presented in this study demonstrate, in quantifiable terms, the protective impact of vaccination in reducing FMD transmission in infected herds. These results will be useful for the parameterization of epidemiological models aimed at quantifying the impact of vaccination and for the design and implementation of FMD emergency vaccination strategies in face of an epidemic.Fil: Brito, B. P.. University of California at Davis; Estados Unidos. Universidad Nacional de Rosario; ArgentinaFil: Perez, Andres Maximiliano. University of California at Davis; Estados Unidos. Universidad Nacional de Rosario; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Cosentino, B.. Ministerio de Agricultura, Ganadería, Pesca y Alimento. Servicio Nacional de Sanidad y Calidad Agroalimentaria; ArgentinaFil: Rodriguez, L. L.. No especifíca;Fil: König, Guido Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Biotecnología; ArgentinaWiley Blackwell Publishing, Inc2011-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/189167Brito, B. P.; Perez, Andres Maximiliano; Cosentino, B.; Rodriguez, L. L.; König, Guido Alberto; Factors Associated With Within-Herd Transmission of Serotype A Foot-and-Mouth Disease Virus in Cattle, During the 2001 Outbreak in Argentina: A Protective Effect of Vaccination; Wiley Blackwell Publishing, Inc; Transboundary And Emerging Diseases; 58; 5; 10-2011; 387-3931865-1674CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1111/j.1865-1682.2011.01217.x/abstractinfo:eu-repo/semantics/altIdentifier/doi/10.1111/j.1865-1682.2011.01217.xinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:32:23Zoai:ri.conicet.gov.ar:11336/189167instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:32:24.027CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Factors Associated With Within-Herd Transmission of Serotype A Foot-and-Mouth Disease Virus in Cattle, During the 2001 Outbreak in Argentina: A Protective Effect of Vaccination
title Factors Associated With Within-Herd Transmission of Serotype A Foot-and-Mouth Disease Virus in Cattle, During the 2001 Outbreak in Argentina: A Protective Effect of Vaccination
spellingShingle Factors Associated With Within-Herd Transmission of Serotype A Foot-and-Mouth Disease Virus in Cattle, During the 2001 Outbreak in Argentina: A Protective Effect of Vaccination
Brito, B. P.
FOOT-AND-MOUTH DISEASE
MODELLING
VACCINATION
WITHIN-HERD TRANSMISSION
title_short Factors Associated With Within-Herd Transmission of Serotype A Foot-and-Mouth Disease Virus in Cattle, During the 2001 Outbreak in Argentina: A Protective Effect of Vaccination
title_full Factors Associated With Within-Herd Transmission of Serotype A Foot-and-Mouth Disease Virus in Cattle, During the 2001 Outbreak in Argentina: A Protective Effect of Vaccination
title_fullStr Factors Associated With Within-Herd Transmission of Serotype A Foot-and-Mouth Disease Virus in Cattle, During the 2001 Outbreak in Argentina: A Protective Effect of Vaccination
title_full_unstemmed Factors Associated With Within-Herd Transmission of Serotype A Foot-and-Mouth Disease Virus in Cattle, During the 2001 Outbreak in Argentina: A Protective Effect of Vaccination
title_sort Factors Associated With Within-Herd Transmission of Serotype A Foot-and-Mouth Disease Virus in Cattle, During the 2001 Outbreak in Argentina: A Protective Effect of Vaccination
dc.creator.none.fl_str_mv Brito, B. P.
Perez, Andres Maximiliano
Cosentino, B.
Rodriguez, L. L.
König, Guido Alberto
author Brito, B. P.
author_facet Brito, B. P.
Perez, Andres Maximiliano
Cosentino, B.
Rodriguez, L. L.
König, Guido Alberto
author_role author
author2 Perez, Andres Maximiliano
Cosentino, B.
Rodriguez, L. L.
König, Guido Alberto
author2_role author
author
author
author
dc.subject.none.fl_str_mv FOOT-AND-MOUTH DISEASE
MODELLING
VACCINATION
WITHIN-HERD TRANSMISSION
topic FOOT-AND-MOUTH DISEASE
MODELLING
VACCINATION
WITHIN-HERD TRANSMISSION
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv Argentina suffered an extensive foot-and-mouth disease (FMD) epidemic between July 2000 and January 2002, 3months after obtaining the official FMD-free without vaccination status conferred by the World Organization for Animal Health. This is one of the largest FMD epidemics controlled by implementation of a systematic mass vaccination campaign in an FMD-free country. In 2000, 124 herds were reported as FMD positive, 2394 herds in 2001 and one in January 2002; the total number of cattle herds in the country at that time was approximately 230000. Estimates of FMD transmission are important to understand the dynamics of disease spread and for estimating the value for the parameterization of disease transmission models, with the ultimate goals of predicting its spread, assessing and designing control strategies, conducting economic analyses and supporting the decision-making process. In this study, the within-herd coefficient of transmission, β, was computed for herds affected in the 2001 FMD epidemic and categorized as low or high based on the median value of β. A logistic regression model was fitted to identify factors significantly associated with high values of β. Results suggested that the odds of having a high within-herd transmission were significantly associated with time from initial herd infection to disease detection, date of report, vaccination, and time from initial herd infection to herd vaccination. Results presented in this study demonstrate, in quantifiable terms, the protective impact of vaccination in reducing FMD transmission in infected herds. These results will be useful for the parameterization of epidemiological models aimed at quantifying the impact of vaccination and for the design and implementation of FMD emergency vaccination strategies in face of an epidemic.
Fil: Brito, B. P.. University of California at Davis; Estados Unidos. Universidad Nacional de Rosario; Argentina
Fil: Perez, Andres Maximiliano. University of California at Davis; Estados Unidos. Universidad Nacional de Rosario; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Cosentino, B.. Ministerio de Agricultura, Ganadería, Pesca y Alimento. Servicio Nacional de Sanidad y Calidad Agroalimentaria; Argentina
Fil: Rodriguez, L. L.. No especifíca;
Fil: König, Guido Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Biotecnología; Argentina
description Argentina suffered an extensive foot-and-mouth disease (FMD) epidemic between July 2000 and January 2002, 3months after obtaining the official FMD-free without vaccination status conferred by the World Organization for Animal Health. This is one of the largest FMD epidemics controlled by implementation of a systematic mass vaccination campaign in an FMD-free country. In 2000, 124 herds were reported as FMD positive, 2394 herds in 2001 and one in January 2002; the total number of cattle herds in the country at that time was approximately 230000. Estimates of FMD transmission are important to understand the dynamics of disease spread and for estimating the value for the parameterization of disease transmission models, with the ultimate goals of predicting its spread, assessing and designing control strategies, conducting economic analyses and supporting the decision-making process. In this study, the within-herd coefficient of transmission, β, was computed for herds affected in the 2001 FMD epidemic and categorized as low or high based on the median value of β. A logistic regression model was fitted to identify factors significantly associated with high values of β. Results suggested that the odds of having a high within-herd transmission were significantly associated with time from initial herd infection to disease detection, date of report, vaccination, and time from initial herd infection to herd vaccination. Results presented in this study demonstrate, in quantifiable terms, the protective impact of vaccination in reducing FMD transmission in infected herds. These results will be useful for the parameterization of epidemiological models aimed at quantifying the impact of vaccination and for the design and implementation of FMD emergency vaccination strategies in face of an epidemic.
publishDate 2011
dc.date.none.fl_str_mv 2011-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/189167
Brito, B. P.; Perez, Andres Maximiliano; Cosentino, B.; Rodriguez, L. L.; König, Guido Alberto; Factors Associated With Within-Herd Transmission of Serotype A Foot-and-Mouth Disease Virus in Cattle, During the 2001 Outbreak in Argentina: A Protective Effect of Vaccination; Wiley Blackwell Publishing, Inc; Transboundary And Emerging Diseases; 58; 5; 10-2011; 387-393
1865-1674
CONICET Digital
CONICET
url http://hdl.handle.net/11336/189167
identifier_str_mv Brito, B. P.; Perez, Andres Maximiliano; Cosentino, B.; Rodriguez, L. L.; König, Guido Alberto; Factors Associated With Within-Herd Transmission of Serotype A Foot-and-Mouth Disease Virus in Cattle, During the 2001 Outbreak in Argentina: A Protective Effect of Vaccination; Wiley Blackwell Publishing, Inc; Transboundary And Emerging Diseases; 58; 5; 10-2011; 387-393
1865-1674
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1111/j.1865-1682.2011.01217.x/abstract
info:eu-repo/semantics/altIdentifier/doi/10.1111/j.1865-1682.2011.01217.x
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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