Sphinganine/sphingosine (SA/SO) ratio and intake of fumonisin contamianted tortillas in a Mexican population

Autores
Landeros, Patricia; Reyes, Waldina; Torres, Adriana Mabel; Rojo, Federico Gabriel Antonio; Chulze, Sofia Noemi
Año de publicación
2005
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The fumonisins are mycotoxins relevant due to their toxicological effects on animals and humans. Based on the current knowledge of the mechanism of action of fumonisins, the sphinganine/sphingosine (Sa/So) ratio is a valid biomarker of exposure in animal studies and could also be useful in human studies if the ratio correlate with fumonisin intake. The Sa/So ratio was evaluated in a Mexican population at three stages of maize based food (tortillas) consumption. A Sa/So ratio higher than 1 was found at the A (regular consumption) and C (re-assumption of the regular consumption) stages, while during the B (stopping of the tortillas consumption for two weeks) stage the Sa/So ratio was lower than 1. This report showed that there is an association between the intake of fumonisin contaminated maize based foods and the elevation of the Sa/So ratio in human samples. Mexican population is exposed with a continuous high consumption of maize based foods commonly contaminated with fumonisins.
Fil: Landeros, Patricia. Universidad de Guadalajara; México
Fil: Reyes, Waldina. Universidad de Guadalajara; México
Fil: Torres, Adriana Mabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina
Fil: Rojo, Federico Gabriel Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina
Fil: Chulze, Sofia Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina
Materia
Sphinganine/sphingosine
Tortillas
Mexican population
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/242640
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/242640
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Sphinganine/sphingosine (SA/SO) ratio and intake of fumonisin contamianted tortillas in a Mexican populationLanderos, PatriciaReyes, WaldinaTorres, Adriana MabelRojo, Federico Gabriel AntonioChulze, Sofia NoemiSphinganine/sphingosineTortillasMexican populationhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The fumonisins are mycotoxins relevant due to their toxicological effects on animals and humans. Based on the current knowledge of the mechanism of action of fumonisins, the sphinganine/sphingosine (Sa/So) ratio is a valid biomarker of exposure in animal studies and could also be useful in human studies if the ratio correlate with fumonisin intake. The Sa/So ratio was evaluated in a Mexican population at three stages of maize based food (tortillas) consumption. A Sa/So ratio higher than 1 was found at the A (regular consumption) and C (re-assumption of the regular consumption) stages, while during the B (stopping of the tortillas consumption for two weeks) stage the Sa/So ratio was lower than 1. This report showed that there is an association between the intake of fumonisin contaminated maize based foods and the elevation of the Sa/So ratio in human samples. Mexican population is exposed with a continuous high consumption of maize based foods commonly contaminated with fumonisins.Fil: Landeros, Patricia. Universidad de Guadalajara; MéxicoFil: Reyes, Waldina. Universidad de Guadalajara; MéxicoFil: Torres, Adriana Mabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; ArgentinaFil: Rojo, Federico Gabriel Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; ArgentinaFil: Chulze, Sofia Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; ArgentinaAsociación Toxicológica Argentina2005-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/242640Landeros, Patricia; Reyes, Waldina; Torres, Adriana Mabel; Rojo, Federico Gabriel Antonio; Chulze, Sofia Noemi; Sphinganine/sphingosine (SA/SO) ratio and intake of fumonisin contamianted tortillas in a Mexican population; Asociación Toxicológica Argentina; Acta Toxicológica Argentina; 13; 2; 12-2005; 8-110327-92861851-3743CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.toxicologia.org.ar/wp-content/uploads/2016/05/Volumen-13-Nro.-2-Diciembre-2005.pdfinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-11-12T09:36:02Zoai:ri.conicet.gov.ar:11336/242640instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-11-12 09:36:03.199CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Sphinganine/sphingosine (SA/SO) ratio and intake of fumonisin contamianted tortillas in a Mexican population
title Sphinganine/sphingosine (SA/SO) ratio and intake of fumonisin contamianted tortillas in a Mexican population
spellingShingle Sphinganine/sphingosine (SA/SO) ratio and intake of fumonisin contamianted tortillas in a Mexican population
Landeros, Patricia
Sphinganine/sphingosine
Tortillas
Mexican population
title_short Sphinganine/sphingosine (SA/SO) ratio and intake of fumonisin contamianted tortillas in a Mexican population
title_full Sphinganine/sphingosine (SA/SO) ratio and intake of fumonisin contamianted tortillas in a Mexican population
title_fullStr Sphinganine/sphingosine (SA/SO) ratio and intake of fumonisin contamianted tortillas in a Mexican population
title_full_unstemmed Sphinganine/sphingosine (SA/SO) ratio and intake of fumonisin contamianted tortillas in a Mexican population
title_sort Sphinganine/sphingosine (SA/SO) ratio and intake of fumonisin contamianted tortillas in a Mexican population
dc.creator.none.fl_str_mv Landeros, Patricia
Reyes, Waldina
Torres, Adriana Mabel
Rojo, Federico Gabriel Antonio
Chulze, Sofia Noemi
author Landeros, Patricia
author_facet Landeros, Patricia
Reyes, Waldina
Torres, Adriana Mabel
Rojo, Federico Gabriel Antonio
Chulze, Sofia Noemi
author_role author
author2 Reyes, Waldina
Torres, Adriana Mabel
Rojo, Federico Gabriel Antonio
Chulze, Sofia Noemi
author2_role author
author
author
author
dc.subject.none.fl_str_mv Sphinganine/sphingosine
Tortillas
Mexican population
topic Sphinganine/sphingosine
Tortillas
Mexican population
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The fumonisins are mycotoxins relevant due to their toxicological effects on animals and humans. Based on the current knowledge of the mechanism of action of fumonisins, the sphinganine/sphingosine (Sa/So) ratio is a valid biomarker of exposure in animal studies and could also be useful in human studies if the ratio correlate with fumonisin intake. The Sa/So ratio was evaluated in a Mexican population at three stages of maize based food (tortillas) consumption. A Sa/So ratio higher than 1 was found at the A (regular consumption) and C (re-assumption of the regular consumption) stages, while during the B (stopping of the tortillas consumption for two weeks) stage the Sa/So ratio was lower than 1. This report showed that there is an association between the intake of fumonisin contaminated maize based foods and the elevation of the Sa/So ratio in human samples. Mexican population is exposed with a continuous high consumption of maize based foods commonly contaminated with fumonisins.
Fil: Landeros, Patricia. Universidad de Guadalajara; México
Fil: Reyes, Waldina. Universidad de Guadalajara; México
Fil: Torres, Adriana Mabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina
Fil: Rojo, Federico Gabriel Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina
Fil: Chulze, Sofia Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina
description The fumonisins are mycotoxins relevant due to their toxicological effects on animals and humans. Based on the current knowledge of the mechanism of action of fumonisins, the sphinganine/sphingosine (Sa/So) ratio is a valid biomarker of exposure in animal studies and could also be useful in human studies if the ratio correlate with fumonisin intake. The Sa/So ratio was evaluated in a Mexican population at three stages of maize based food (tortillas) consumption. A Sa/So ratio higher than 1 was found at the A (regular consumption) and C (re-assumption of the regular consumption) stages, while during the B (stopping of the tortillas consumption for two weeks) stage the Sa/So ratio was lower than 1. This report showed that there is an association between the intake of fumonisin contaminated maize based foods and the elevation of the Sa/So ratio in human samples. Mexican population is exposed with a continuous high consumption of maize based foods commonly contaminated with fumonisins.
publishDate 2005
dc.date.none.fl_str_mv 2005-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/242640
Landeros, Patricia; Reyes, Waldina; Torres, Adriana Mabel; Rojo, Federico Gabriel Antonio; Chulze, Sofia Noemi; Sphinganine/sphingosine (SA/SO) ratio and intake of fumonisin contamianted tortillas in a Mexican population; Asociación Toxicológica Argentina; Acta Toxicológica Argentina; 13; 2; 12-2005; 8-11
0327-9286
1851-3743
CONICET Digital
CONICET
url http://hdl.handle.net/11336/242640
identifier_str_mv Landeros, Patricia; Reyes, Waldina; Torres, Adriana Mabel; Rojo, Federico Gabriel Antonio; Chulze, Sofia Noemi; Sphinganine/sphingosine (SA/SO) ratio and intake of fumonisin contamianted tortillas in a Mexican population; Asociación Toxicológica Argentina; Acta Toxicológica Argentina; 13; 2; 12-2005; 8-11
0327-9286
1851-3743
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.toxicologia.org.ar/wp-content/uploads/2016/05/Volumen-13-Nro.-2-Diciembre-2005.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Asociación Toxicológica Argentina
publisher.none.fl_str_mv Asociación Toxicológica Argentina
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1848597234768150528
score 13.142177

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