Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA

Autores
Ivanovic, Jasna; Knauer, Sandra; Fanovich, Maria Alejandra; Milovanovic, Stoja; Stamenic, Marko; Jaeger, Philip; Zizovic, Irena; Eggers, Rudolf
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The potential of supercritical carbon dioxide (scCO2) processing of polycaprolactone (PCL) and polycaprolactone-hydroxyapatite (PCL-HA) composites for obtaining functional porous scaffolds at moderate temperatures (35-40 °C) was analyzed and quantified. The effect of scCO2 sorption kinetics on the swelling, foam morphology and thermal behavior of the PCL and PCL-HA composites was studied. Sorption isotherms were determined using magnetic suspension balance at 10-30 MPa and 35-40 °C. Influence of the pressure, HA amount (10-20%) and procedure for HA powder preparation on the sorption kinetics was discussed. Supercritical solvent impregnation (SSI) of PCL and PCL-HA with thymol was investigated as environmentally friendly way to produce functional scaffolds with controlled microstructure. Moderately high pressures (13-17 MPa) and 10% of HA were proven to be favorable for creation of the PCL scaffolds with satisfying foam microstructure (mean pore size ∼200-300 μm), filler distribution and thymol impregnation yields (12-18%). This was due to the satisfactory high scCO2 solubility (0.25-0.30 g/g) and mass transfer rate (∼10-10 m2/s) in the polymer phase as well as its great plasticizing effect (-ΔTm = 26.4-27.4 °C). Higher saturation of the polymer phase with scCO2 (0.30-0.55 g/g), filler amount (20%) and thymol solubility in scCO2 (>5.5 g/kg) at pressures above 20 MPa resulted in decreased mass transfer rate and SSI efficiency.
Fil: Ivanovic, Jasna. University of Belgrade. Faculty of Technology and Metallurgy; Serbia
Fil: Knauer, Sandra. Eurotechnica; Alemania
Fil: Fanovich, Maria Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; Argentina
Fil: Milovanovic, Stoja. University of Belgrade. Faculty of Technology and Metallurgy; Serbia
Fil: Stamenic, Marko. University of Belgrade. Faculty of Technology and Metallurgy; Serbia
Fil: Jaeger, Philip. Eurotechnica; Alemania
Fil: Zizovic, Irena. University of Belgrade. Faculty of Technology and Metallurgy; Serbia
Fil: Eggers, Rudolf. Hamburg University of Technology; Alemania
Materia
Co2 Sorption Kinetics
High-Pressure Dsc
Melting Point Depression
Polycaprolactone
Polycaprolactone-Hydroxyapatite
Thymol Impregnation
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/39602
Acceder
id CONICETDig_8d774cabb60c1142f6e4b05abdb380ce
oai_identifier_str oai:ri.conicet.gov.ar:11336/39602
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HAIvanovic, JasnaKnauer, SandraFanovich, Maria AlejandraMilovanovic, StojaStamenic, MarkoJaeger, PhilipZizovic, IrenaEggers, RudolfCo2 Sorption KineticsHigh-Pressure DscMelting Point DepressionPolycaprolactonePolycaprolactone-HydroxyapatiteThymol Impregnationhttps://purl.org/becyt/ford/2.5https://purl.org/becyt/ford/2The potential of supercritical carbon dioxide (scCO2) processing of polycaprolactone (PCL) and polycaprolactone-hydroxyapatite (PCL-HA) composites for obtaining functional porous scaffolds at moderate temperatures (35-40 °C) was analyzed and quantified. The effect of scCO2 sorption kinetics on the swelling, foam morphology and thermal behavior of the PCL and PCL-HA composites was studied. Sorption isotherms were determined using magnetic suspension balance at 10-30 MPa and 35-40 °C. Influence of the pressure, HA amount (10-20%) and procedure for HA powder preparation on the sorption kinetics was discussed. Supercritical solvent impregnation (SSI) of PCL and PCL-HA with thymol was investigated as environmentally friendly way to produce functional scaffolds with controlled microstructure. Moderately high pressures (13-17 MPa) and 10% of HA were proven to be favorable for creation of the PCL scaffolds with satisfying foam microstructure (mean pore size ∼200-300 μm), filler distribution and thymol impregnation yields (12-18%). This was due to the satisfactory high scCO2 solubility (0.25-0.30 g/g) and mass transfer rate (∼10-10 m2/s) in the polymer phase as well as its great plasticizing effect (-ΔTm = 26.4-27.4 °C). Higher saturation of the polymer phase with scCO2 (0.30-0.55 g/g), filler amount (20%) and thymol solubility in scCO2 (>5.5 g/kg) at pressures above 20 MPa resulted in decreased mass transfer rate and SSI efficiency.Fil: Ivanovic, Jasna. University of Belgrade. Faculty of Technology and Metallurgy; SerbiaFil: Knauer, Sandra. Eurotechnica; AlemaniaFil: Fanovich, Maria Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Milovanovic, Stoja. University of Belgrade. Faculty of Technology and Metallurgy; SerbiaFil: Stamenic, Marko. University of Belgrade. Faculty of Technology and Metallurgy; SerbiaFil: Jaeger, Philip. Eurotechnica; AlemaniaFil: Zizovic, Irena. University of Belgrade. Faculty of Technology and Metallurgy; SerbiaFil: Eggers, Rudolf. Hamburg University of Technology; AlemaniaElsevier Science2016-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/39602Ivanovic, Jasna; Knauer, Sandra; Fanovich, Maria Alejandra; Milovanovic, Stoja; Stamenic, Marko; et al.; Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA; Elsevier Science; Journal of Supercritical Fluids; 107; 1-2016; 486-4980896-8446CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.supflu.2015.07.001info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0896844615300541info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:35:56Zoai:ri.conicet.gov.ar:11336/39602instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:35:56.59CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA
title Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA
spellingShingle Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA
Ivanovic, Jasna
Co2 Sorption Kinetics
High-Pressure Dsc
Melting Point Depression
Polycaprolactone
Polycaprolactone-Hydroxyapatite
Thymol Impregnation
title_short Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA
title_full Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA
title_fullStr Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA
title_full_unstemmed Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA
title_sort Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA
dc.creator.none.fl_str_mv Ivanovic, Jasna
Knauer, Sandra
Fanovich, Maria Alejandra
Milovanovic, Stoja
Stamenic, Marko
Jaeger, Philip
Zizovic, Irena
Eggers, Rudolf
author Ivanovic, Jasna
author_facet Ivanovic, Jasna
Knauer, Sandra
Fanovich, Maria Alejandra
Milovanovic, Stoja
Stamenic, Marko
Jaeger, Philip
Zizovic, Irena
Eggers, Rudolf
author_role author
author2 Knauer, Sandra
Fanovich, Maria Alejandra
Milovanovic, Stoja
Stamenic, Marko
Jaeger, Philip
Zizovic, Irena
Eggers, Rudolf
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Co2 Sorption Kinetics
High-Pressure Dsc
Melting Point Depression
Polycaprolactone
Polycaprolactone-Hydroxyapatite
Thymol Impregnation
topic Co2 Sorption Kinetics
High-Pressure Dsc
Melting Point Depression
Polycaprolactone
Polycaprolactone-Hydroxyapatite
Thymol Impregnation
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv The potential of supercritical carbon dioxide (scCO2) processing of polycaprolactone (PCL) and polycaprolactone-hydroxyapatite (PCL-HA) composites for obtaining functional porous scaffolds at moderate temperatures (35-40 °C) was analyzed and quantified. The effect of scCO2 sorption kinetics on the swelling, foam morphology and thermal behavior of the PCL and PCL-HA composites was studied. Sorption isotherms were determined using magnetic suspension balance at 10-30 MPa and 35-40 °C. Influence of the pressure, HA amount (10-20%) and procedure for HA powder preparation on the sorption kinetics was discussed. Supercritical solvent impregnation (SSI) of PCL and PCL-HA with thymol was investigated as environmentally friendly way to produce functional scaffolds with controlled microstructure. Moderately high pressures (13-17 MPa) and 10% of HA were proven to be favorable for creation of the PCL scaffolds with satisfying foam microstructure (mean pore size ∼200-300 μm), filler distribution and thymol impregnation yields (12-18%). This was due to the satisfactory high scCO2 solubility (0.25-0.30 g/g) and mass transfer rate (∼10-10 m2/s) in the polymer phase as well as its great plasticizing effect (-ΔTm = 26.4-27.4 °C). Higher saturation of the polymer phase with scCO2 (0.30-0.55 g/g), filler amount (20%) and thymol solubility in scCO2 (>5.5 g/kg) at pressures above 20 MPa resulted in decreased mass transfer rate and SSI efficiency.
Fil: Ivanovic, Jasna. University of Belgrade. Faculty of Technology and Metallurgy; Serbia
Fil: Knauer, Sandra. Eurotechnica; Alemania
Fil: Fanovich, Maria Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; Argentina
Fil: Milovanovic, Stoja. University of Belgrade. Faculty of Technology and Metallurgy; Serbia
Fil: Stamenic, Marko. University of Belgrade. Faculty of Technology and Metallurgy; Serbia
Fil: Jaeger, Philip. Eurotechnica; Alemania
Fil: Zizovic, Irena. University of Belgrade. Faculty of Technology and Metallurgy; Serbia
Fil: Eggers, Rudolf. Hamburg University of Technology; Alemania
description The potential of supercritical carbon dioxide (scCO2) processing of polycaprolactone (PCL) and polycaprolactone-hydroxyapatite (PCL-HA) composites for obtaining functional porous scaffolds at moderate temperatures (35-40 °C) was analyzed and quantified. The effect of scCO2 sorption kinetics on the swelling, foam morphology and thermal behavior of the PCL and PCL-HA composites was studied. Sorption isotherms were determined using magnetic suspension balance at 10-30 MPa and 35-40 °C. Influence of the pressure, HA amount (10-20%) and procedure for HA powder preparation on the sorption kinetics was discussed. Supercritical solvent impregnation (SSI) of PCL and PCL-HA with thymol was investigated as environmentally friendly way to produce functional scaffolds with controlled microstructure. Moderately high pressures (13-17 MPa) and 10% of HA were proven to be favorable for creation of the PCL scaffolds with satisfying foam microstructure (mean pore size ∼200-300 μm), filler distribution and thymol impregnation yields (12-18%). This was due to the satisfactory high scCO2 solubility (0.25-0.30 g/g) and mass transfer rate (∼10-10 m2/s) in the polymer phase as well as its great plasticizing effect (-ΔTm = 26.4-27.4 °C). Higher saturation of the polymer phase with scCO2 (0.30-0.55 g/g), filler amount (20%) and thymol solubility in scCO2 (>5.5 g/kg) at pressures above 20 MPa resulted in decreased mass transfer rate and SSI efficiency.
publishDate 2016
dc.date.none.fl_str_mv 2016-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/39602
Ivanovic, Jasna; Knauer, Sandra; Fanovich, Maria Alejandra; Milovanovic, Stoja; Stamenic, Marko; et al.; Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA; Elsevier Science; Journal of Supercritical Fluids; 107; 1-2016; 486-498
0896-8446
CONICET Digital
CONICET
url http://hdl.handle.net/11336/39602
identifier_str_mv Ivanovic, Jasna; Knauer, Sandra; Fanovich, Maria Alejandra; Milovanovic, Stoja; Stamenic, Marko; et al.; Supercritical CO2 sorption kinetics and thymol impregnation of PCL and PCL-HA; Elsevier Science; Journal of Supercritical Fluids; 107; 1-2016; 486-498
0896-8446
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.supflu.2015.07.001
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0896844615300541
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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