Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical app...

Autores
Machado, Noelia Daiana; Cejudo Bastante, Cristina; Goñi, Maria Laura; Gañan, Nicolas Alberto; Casas Cardoso, Lourdes; Mantell Serrano, Casimiro
Año de publicación
2022
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The leaves of Olea europaea as agricultural waste represent a convenient source of antioxi-dants. In combination with supercritical CO2 (scCO2), assisted impregnation is an interesting strategy for the preparation of biomedical devices with specific bioactivity. For this purpose, 3D-printable filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) were employed for the supercritical impregnation of ethanolic olive leaves extract (OLE) for biomedical application. The extraction of OLE was performed using pressurized liquids. The effect of pressure (100–400 bar), temperature (35–55 °C), and the polymer type on the OLE impregnation and the swelling degree were studied including a morphological analysis and the measurement of the final antioxidant ac-tivity. All the studied variables as well as their interactions showed significant effects on the OLE loading. Higher temperatures favored the OLE loading while the pressure presented opposite effects at values higher than 250 bar. Thus, the highest OLE loadings were achieved at 250 bar and 55 °C for both polymers. However, TPU showed c.a. 4 times higher OLE loading and antioxidant activity in comparison with PLA at the optimal conditions. To the best of our knowledge, this is the first report using TPU for the supercritical impregnation of a natural extract with bioactivity.
Fil: Machado, Noelia Daiana. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; Argentina
Fil: Cejudo Bastante, Cristina. Universidad de Cadiz. Facultad de Ciencias; España
Fil: Goñi, Maria Laura. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; Argentina
Fil: Gañan, Nicolas Alberto. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; Argentina
Fil: Casas Cardoso, Lourdes. Universidad de Cadiz. Facultad de Ciencias; España
Fil: Mantell Serrano, Casimiro. Universidad de Cadiz. Facultad de Ciencias; España
Materia
ANTIOXIDANT ACTIVITY
OLIVE LEAVES EXTRACT
POLYLACTIC ACID
SUPERCRITICAL IMPREGNATION
THERMOPLASTIC POLYURETHANE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/203490
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applicationsMachado, Noelia DaianaCejudo Bastante, CristinaGoñi, Maria LauraGañan, Nicolas AlbertoCasas Cardoso, LourdesMantell Serrano, CasimiroANTIOXIDANT ACTIVITYOLIVE LEAVES EXTRACTPOLYLACTIC ACIDSUPERCRITICAL IMPREGNATIONTHERMOPLASTIC POLYURETHANEhttps://purl.org/becyt/ford/2.4https://purl.org/becyt/ford/2The leaves of Olea europaea as agricultural waste represent a convenient source of antioxi-dants. In combination with supercritical CO2 (scCO2), assisted impregnation is an interesting strategy for the preparation of biomedical devices with specific bioactivity. For this purpose, 3D-printable filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) were employed for the supercritical impregnation of ethanolic olive leaves extract (OLE) for biomedical application. The extraction of OLE was performed using pressurized liquids. The effect of pressure (100–400 bar), temperature (35–55 °C), and the polymer type on the OLE impregnation and the swelling degree were studied including a morphological analysis and the measurement of the final antioxidant ac-tivity. All the studied variables as well as their interactions showed significant effects on the OLE loading. Higher temperatures favored the OLE loading while the pressure presented opposite effects at values higher than 250 bar. Thus, the highest OLE loadings were achieved at 250 bar and 55 °C for both polymers. However, TPU showed c.a. 4 times higher OLE loading and antioxidant activity in comparison with PLA at the optimal conditions. To the best of our knowledge, this is the first report using TPU for the supercritical impregnation of a natural extract with bioactivity.Fil: Machado, Noelia Daiana. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; ArgentinaFil: Cejudo Bastante, Cristina. Universidad de Cadiz. Facultad de Ciencias; EspañaFil: Goñi, Maria Laura. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; ArgentinaFil: Gañan, Nicolas Alberto. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; ArgentinaFil: Casas Cardoso, Lourdes. Universidad de Cadiz. Facultad de Ciencias; EspañaFil: Mantell Serrano, Casimiro. Universidad de Cadiz. Facultad de Ciencias; EspañaMultidisciplinary Digital Publishing Institute2022-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/203490Machado, Noelia Daiana; Cejudo Bastante, Cristina; Goñi, Maria Laura; Gañan, Nicolas Alberto; Casas Cardoso, Lourdes; et al.; Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications; Multidisciplinary Digital Publishing Institute; Antioxidants; 11; 6; 6-2022; 1106-11702076-3921CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2076-3921/11/6/1170/htminfo:eu-repo/semantics/altIdentifier/doi/10.3390/antiox11061170info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T12:06:37Zoai:ri.conicet.gov.ar:11336/203490instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 12:06:38.182CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications
title Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications
spellingShingle Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications
Machado, Noelia Daiana
ANTIOXIDANT ACTIVITY
OLIVE LEAVES EXTRACT
POLYLACTIC ACID
SUPERCRITICAL IMPREGNATION
THERMOPLASTIC POLYURETHANE
title_short Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications
title_full Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications
title_fullStr Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications
title_full_unstemmed Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications
title_sort Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications
dc.creator.none.fl_str_mv Machado, Noelia Daiana
Cejudo Bastante, Cristina
Goñi, Maria Laura
Gañan, Nicolas Alberto
Casas Cardoso, Lourdes
Mantell Serrano, Casimiro
author Machado, Noelia Daiana
author_facet Machado, Noelia Daiana
Cejudo Bastante, Cristina
Goñi, Maria Laura
Gañan, Nicolas Alberto
Casas Cardoso, Lourdes
Mantell Serrano, Casimiro
author_role author
author2 Cejudo Bastante, Cristina
Goñi, Maria Laura
Gañan, Nicolas Alberto
Casas Cardoso, Lourdes
Mantell Serrano, Casimiro
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv ANTIOXIDANT ACTIVITY
OLIVE LEAVES EXTRACT
POLYLACTIC ACID
SUPERCRITICAL IMPREGNATION
THERMOPLASTIC POLYURETHANE
topic ANTIOXIDANT ACTIVITY
OLIVE LEAVES EXTRACT
POLYLACTIC ACID
SUPERCRITICAL IMPREGNATION
THERMOPLASTIC POLYURETHANE
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.4
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv The leaves of Olea europaea as agricultural waste represent a convenient source of antioxi-dants. In combination with supercritical CO2 (scCO2), assisted impregnation is an interesting strategy for the preparation of biomedical devices with specific bioactivity. For this purpose, 3D-printable filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) were employed for the supercritical impregnation of ethanolic olive leaves extract (OLE) for biomedical application. The extraction of OLE was performed using pressurized liquids. The effect of pressure (100–400 bar), temperature (35–55 °C), and the polymer type on the OLE impregnation and the swelling degree were studied including a morphological analysis and the measurement of the final antioxidant ac-tivity. All the studied variables as well as their interactions showed significant effects on the OLE loading. Higher temperatures favored the OLE loading while the pressure presented opposite effects at values higher than 250 bar. Thus, the highest OLE loadings were achieved at 250 bar and 55 °C for both polymers. However, TPU showed c.a. 4 times higher OLE loading and antioxidant activity in comparison with PLA at the optimal conditions. To the best of our knowledge, this is the first report using TPU for the supercritical impregnation of a natural extract with bioactivity.
Fil: Machado, Noelia Daiana. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; Argentina
Fil: Cejudo Bastante, Cristina. Universidad de Cadiz. Facultad de Ciencias; España
Fil: Goñi, Maria Laura. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; Argentina
Fil: Gañan, Nicolas Alberto. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; Argentina
Fil: Casas Cardoso, Lourdes. Universidad de Cadiz. Facultad de Ciencias; España
Fil: Mantell Serrano, Casimiro. Universidad de Cadiz. Facultad de Ciencias; España
description The leaves of Olea europaea as agricultural waste represent a convenient source of antioxi-dants. In combination with supercritical CO2 (scCO2), assisted impregnation is an interesting strategy for the preparation of biomedical devices with specific bioactivity. For this purpose, 3D-printable filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) were employed for the supercritical impregnation of ethanolic olive leaves extract (OLE) for biomedical application. The extraction of OLE was performed using pressurized liquids. The effect of pressure (100–400 bar), temperature (35–55 °C), and the polymer type on the OLE impregnation and the swelling degree were studied including a morphological analysis and the measurement of the final antioxidant ac-tivity. All the studied variables as well as their interactions showed significant effects on the OLE loading. Higher temperatures favored the OLE loading while the pressure presented opposite effects at values higher than 250 bar. Thus, the highest OLE loadings were achieved at 250 bar and 55 °C for both polymers. However, TPU showed c.a. 4 times higher OLE loading and antioxidant activity in comparison with PLA at the optimal conditions. To the best of our knowledge, this is the first report using TPU for the supercritical impregnation of a natural extract with bioactivity.
publishDate 2022
dc.date.none.fl_str_mv 2022-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/203490
Machado, Noelia Daiana; Cejudo Bastante, Cristina; Goñi, Maria Laura; Gañan, Nicolas Alberto; Casas Cardoso, Lourdes; et al.; Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications; Multidisciplinary Digital Publishing Institute; Antioxidants; 11; 6; 6-2022; 1106-1170
2076-3921
CONICET Digital
CONICET
url http://hdl.handle.net/11336/203490
identifier_str_mv Machado, Noelia Daiana; Cejudo Bastante, Cristina; Goñi, Maria Laura; Gañan, Nicolas Alberto; Casas Cardoso, Lourdes; et al.; Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications; Multidisciplinary Digital Publishing Institute; Antioxidants; 11; 6; 6-2022; 1106-1170
2076-3921
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2076-3921/11/6/1170/htm
info:eu-repo/semantics/altIdentifier/doi/10.3390/antiox11061170
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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