Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical app...
- Autores
- Machado, Noelia Daiana; Cejudo Bastante, Cristina; Goñi, Maria Laura; Gañan, Nicolas Alberto; Casas Cardoso, Lourdes; Mantell Serrano, Casimiro
- Año de publicación
- 2022
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- The leaves of Olea europaea as agricultural waste represent a convenient source of antioxi-dants. In combination with supercritical CO2 (scCO2), assisted impregnation is an interesting strategy for the preparation of biomedical devices with specific bioactivity. For this purpose, 3D-printable filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) were employed for the supercritical impregnation of ethanolic olive leaves extract (OLE) for biomedical application. The extraction of OLE was performed using pressurized liquids. The effect of pressure (100–400 bar), temperature (35–55 °C), and the polymer type on the OLE impregnation and the swelling degree were studied including a morphological analysis and the measurement of the final antioxidant ac-tivity. All the studied variables as well as their interactions showed significant effects on the OLE loading. Higher temperatures favored the OLE loading while the pressure presented opposite effects at values higher than 250 bar. Thus, the highest OLE loadings were achieved at 250 bar and 55 °C for both polymers. However, TPU showed c.a. 4 times higher OLE loading and antioxidant activity in comparison with PLA at the optimal conditions. To the best of our knowledge, this is the first report using TPU for the supercritical impregnation of a natural extract with bioactivity.
Fil: Machado, Noelia Daiana. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; Argentina
Fil: Cejudo Bastante, Cristina. Universidad de Cadiz. Facultad de Ciencias; España
Fil: Goñi, Maria Laura. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; Argentina
Fil: Gañan, Nicolas Alberto. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; Argentina
Fil: Casas Cardoso, Lourdes. Universidad de Cadiz. Facultad de Ciencias; España
Fil: Mantell Serrano, Casimiro. Universidad de Cadiz. Facultad de Ciencias; España - Materia
-
ANTIOXIDANT ACTIVITY
OLIVE LEAVES EXTRACT
POLYLACTIC ACID
SUPERCRITICAL IMPREGNATION
THERMOPLASTIC POLYURETHANE - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/203490
Ver los metadatos del registro completo
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Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applicationsMachado, Noelia DaianaCejudo Bastante, CristinaGoñi, Maria LauraGañan, Nicolas AlbertoCasas Cardoso, LourdesMantell Serrano, CasimiroANTIOXIDANT ACTIVITYOLIVE LEAVES EXTRACTPOLYLACTIC ACIDSUPERCRITICAL IMPREGNATIONTHERMOPLASTIC POLYURETHANEhttps://purl.org/becyt/ford/2.4https://purl.org/becyt/ford/2The leaves of Olea europaea as agricultural waste represent a convenient source of antioxi-dants. In combination with supercritical CO2 (scCO2), assisted impregnation is an interesting strategy for the preparation of biomedical devices with specific bioactivity. For this purpose, 3D-printable filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) were employed for the supercritical impregnation of ethanolic olive leaves extract (OLE) for biomedical application. The extraction of OLE was performed using pressurized liquids. The effect of pressure (100–400 bar), temperature (35–55 °C), and the polymer type on the OLE impregnation and the swelling degree were studied including a morphological analysis and the measurement of the final antioxidant ac-tivity. All the studied variables as well as their interactions showed significant effects on the OLE loading. Higher temperatures favored the OLE loading while the pressure presented opposite effects at values higher than 250 bar. Thus, the highest OLE loadings were achieved at 250 bar and 55 °C for both polymers. However, TPU showed c.a. 4 times higher OLE loading and antioxidant activity in comparison with PLA at the optimal conditions. To the best of our knowledge, this is the first report using TPU for the supercritical impregnation of a natural extract with bioactivity.Fil: Machado, Noelia Daiana. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; ArgentinaFil: Cejudo Bastante, Cristina. Universidad de Cadiz. Facultad de Ciencias; EspañaFil: Goñi, Maria Laura. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; ArgentinaFil: Gañan, Nicolas Alberto. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; ArgentinaFil: Casas Cardoso, Lourdes. Universidad de Cadiz. Facultad de Ciencias; EspañaFil: Mantell Serrano, Casimiro. Universidad de Cadiz. Facultad de Ciencias; EspañaMultidisciplinary Digital Publishing Institute2022-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/203490Machado, Noelia Daiana; Cejudo Bastante, Cristina; Goñi, Maria Laura; Gañan, Nicolas Alberto; Casas Cardoso, Lourdes; et al.; Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications; Multidisciplinary Digital Publishing Institute; Antioxidants; 11; 6; 6-2022; 1106-11702076-3921CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2076-3921/11/6/1170/htminfo:eu-repo/semantics/altIdentifier/doi/10.3390/antiox11061170info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:34:09Zoai:ri.conicet.gov.ar:11336/203490instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:34:10.235CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications |
title |
Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications |
spellingShingle |
Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications Machado, Noelia Daiana ANTIOXIDANT ACTIVITY OLIVE LEAVES EXTRACT POLYLACTIC ACID SUPERCRITICAL IMPREGNATION THERMOPLASTIC POLYURETHANE |
title_short |
Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications |
title_full |
Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications |
title_fullStr |
Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications |
title_full_unstemmed |
Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications |
title_sort |
Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications |
dc.creator.none.fl_str_mv |
Machado, Noelia Daiana Cejudo Bastante, Cristina Goñi, Maria Laura Gañan, Nicolas Alberto Casas Cardoso, Lourdes Mantell Serrano, Casimiro |
author |
Machado, Noelia Daiana |
author_facet |
Machado, Noelia Daiana Cejudo Bastante, Cristina Goñi, Maria Laura Gañan, Nicolas Alberto Casas Cardoso, Lourdes Mantell Serrano, Casimiro |
author_role |
author |
author2 |
Cejudo Bastante, Cristina Goñi, Maria Laura Gañan, Nicolas Alberto Casas Cardoso, Lourdes Mantell Serrano, Casimiro |
author2_role |
author author author author author |
dc.subject.none.fl_str_mv |
ANTIOXIDANT ACTIVITY OLIVE LEAVES EXTRACT POLYLACTIC ACID SUPERCRITICAL IMPREGNATION THERMOPLASTIC POLYURETHANE |
topic |
ANTIOXIDANT ACTIVITY OLIVE LEAVES EXTRACT POLYLACTIC ACID SUPERCRITICAL IMPREGNATION THERMOPLASTIC POLYURETHANE |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/2.4 https://purl.org/becyt/ford/2 |
dc.description.none.fl_txt_mv |
The leaves of Olea europaea as agricultural waste represent a convenient source of antioxi-dants. In combination with supercritical CO2 (scCO2), assisted impregnation is an interesting strategy for the preparation of biomedical devices with specific bioactivity. For this purpose, 3D-printable filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) were employed for the supercritical impregnation of ethanolic olive leaves extract (OLE) for biomedical application. The extraction of OLE was performed using pressurized liquids. The effect of pressure (100–400 bar), temperature (35–55 °C), and the polymer type on the OLE impregnation and the swelling degree were studied including a morphological analysis and the measurement of the final antioxidant ac-tivity. All the studied variables as well as their interactions showed significant effects on the OLE loading. Higher temperatures favored the OLE loading while the pressure presented opposite effects at values higher than 250 bar. Thus, the highest OLE loadings were achieved at 250 bar and 55 °C for both polymers. However, TPU showed c.a. 4 times higher OLE loading and antioxidant activity in comparison with PLA at the optimal conditions. To the best of our knowledge, this is the first report using TPU for the supercritical impregnation of a natural extract with bioactivity. Fil: Machado, Noelia Daiana. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; Argentina Fil: Cejudo Bastante, Cristina. Universidad de Cadiz. Facultad de Ciencias; España Fil: Goñi, Maria Laura. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; Argentina Fil: Gañan, Nicolas Alberto. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Ciencias y Tecnología de los Alimentos; Argentina Fil: Casas Cardoso, Lourdes. Universidad de Cadiz. Facultad de Ciencias; España Fil: Mantell Serrano, Casimiro. Universidad de Cadiz. Facultad de Ciencias; España |
description |
The leaves of Olea europaea as agricultural waste represent a convenient source of antioxi-dants. In combination with supercritical CO2 (scCO2), assisted impregnation is an interesting strategy for the preparation of biomedical devices with specific bioactivity. For this purpose, 3D-printable filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) were employed for the supercritical impregnation of ethanolic olive leaves extract (OLE) for biomedical application. The extraction of OLE was performed using pressurized liquids. The effect of pressure (100–400 bar), temperature (35–55 °C), and the polymer type on the OLE impregnation and the swelling degree were studied including a morphological analysis and the measurement of the final antioxidant ac-tivity. All the studied variables as well as their interactions showed significant effects on the OLE loading. Higher temperatures favored the OLE loading while the pressure presented opposite effects at values higher than 250 bar. Thus, the highest OLE loadings were achieved at 250 bar and 55 °C for both polymers. However, TPU showed c.a. 4 times higher OLE loading and antioxidant activity in comparison with PLA at the optimal conditions. To the best of our knowledge, this is the first report using TPU for the supercritical impregnation of a natural extract with bioactivity. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-06 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/203490 Machado, Noelia Daiana; Cejudo Bastante, Cristina; Goñi, Maria Laura; Gañan, Nicolas Alberto; Casas Cardoso, Lourdes; et al.; Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications; Multidisciplinary Digital Publishing Institute; Antioxidants; 11; 6; 6-2022; 1106-1170 2076-3921 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/203490 |
identifier_str_mv |
Machado, Noelia Daiana; Cejudo Bastante, Cristina; Goñi, Maria Laura; Gañan, Nicolas Alberto; Casas Cardoso, Lourdes; et al.; Screening of the supercritical impregnation of olea europaea leaves extract into filaments of thermoplastic polyurethane (TPU) and polylactic acid (PLA) intended for biomedical applications; Multidisciplinary Digital Publishing Institute; Antioxidants; 11; 6; 6-2022; 1106-1170 2076-3921 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2076-3921/11/6/1170/htm info:eu-repo/semantics/altIdentifier/doi/10.3390/antiox11061170 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Multidisciplinary Digital Publishing Institute |
publisher.none.fl_str_mv |
Multidisciplinary Digital Publishing Institute |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844614357990768640 |
score |
13.070432 |