SARS‐CoV‐2 virus and liver expression of host receptors: putative mechanisms of liver involvement in COVID‐19

Autores
Pirola, Carlos José; Sookoian, Silvia Cristina
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Zhang et al. showed that COVID‐19 affected patients’ present liver biochemistry abnormalities, including elevation of aminotransferases, gamma‐glutamyl transferase, and alkaline phosphatase 1. Hence, several possible clinical scenarios in the setting of liver diseases have been postulated. First, patients with chronic liver disease may be more vulnerable to the severe clinical consequences of COVID‐19, including oxygen desaturation and hypoxemia due to severe pneumonia or the cytokine storm 1;2. Second, liver biochemistry abnormalities are the consequence of drug toxicity.
Fil: Pirola, Carlos José. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Sookoian, Silvia Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Materia
COVID-19
HEPATITIS
SARS-CoV-2
TRANSAMINASES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/106197
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling SARS‐CoV‐2 virus and liver expression of host receptors: putative mechanisms of liver involvement in COVID‐19Pirola, Carlos JoséSookoian, Silvia CristinaCOVID-19HEPATITISSARS-CoV-2TRANSAMINASEShttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Zhang et al. showed that COVID‐19 affected patients’ present liver biochemistry abnormalities, including elevation of aminotransferases, gamma‐glutamyl transferase, and alkaline phosphatase 1. Hence, several possible clinical scenarios in the setting of liver diseases have been postulated. First, patients with chronic liver disease may be more vulnerable to the severe clinical consequences of COVID‐19, including oxygen desaturation and hypoxemia due to severe pneumonia or the cytokine storm 1;2. Second, liver biochemistry abnormalities are the consequence of drug toxicity.Fil: Pirola, Carlos José. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaFil: Sookoian, Silvia Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaWiley Blackwell Publishing, Inc2020-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/106197Pirola, Carlos José; Sookoian, Silvia Cristina; SARS‐CoV‐2 virus and liver expression of host receptors: putative mechanisms of liver involvement in COVID‐19; Wiley Blackwell Publishing, Inc; Liver International; 4-2020; 1-71478-3223CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1111/liv.14500info:eu-repo/semantics/altIdentifier/doi/10.1111/liv.14500info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:17:20Zoai:ri.conicet.gov.ar:11336/106197instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:17:20.517CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv SARS‐CoV‐2 virus and liver expression of host receptors: putative mechanisms of liver involvement in COVID‐19
title SARS‐CoV‐2 virus and liver expression of host receptors: putative mechanisms of liver involvement in COVID‐19
spellingShingle SARS‐CoV‐2 virus and liver expression of host receptors: putative mechanisms of liver involvement in COVID‐19
Pirola, Carlos José
COVID-19
HEPATITIS
SARS-CoV-2
TRANSAMINASES
title_short SARS‐CoV‐2 virus and liver expression of host receptors: putative mechanisms of liver involvement in COVID‐19
title_full SARS‐CoV‐2 virus and liver expression of host receptors: putative mechanisms of liver involvement in COVID‐19
title_fullStr SARS‐CoV‐2 virus and liver expression of host receptors: putative mechanisms of liver involvement in COVID‐19
title_full_unstemmed SARS‐CoV‐2 virus and liver expression of host receptors: putative mechanisms of liver involvement in COVID‐19
title_sort SARS‐CoV‐2 virus and liver expression of host receptors: putative mechanisms of liver involvement in COVID‐19
dc.creator.none.fl_str_mv Pirola, Carlos José
Sookoian, Silvia Cristina
author Pirola, Carlos José
author_facet Pirola, Carlos José
Sookoian, Silvia Cristina
author_role author
author2 Sookoian, Silvia Cristina
author2_role author
dc.subject.none.fl_str_mv COVID-19
HEPATITIS
SARS-CoV-2
TRANSAMINASES
topic COVID-19
HEPATITIS
SARS-CoV-2
TRANSAMINASES
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Zhang et al. showed that COVID‐19 affected patients’ present liver biochemistry abnormalities, including elevation of aminotransferases, gamma‐glutamyl transferase, and alkaline phosphatase 1. Hence, several possible clinical scenarios in the setting of liver diseases have been postulated. First, patients with chronic liver disease may be more vulnerable to the severe clinical consequences of COVID‐19, including oxygen desaturation and hypoxemia due to severe pneumonia or the cytokine storm 1;2. Second, liver biochemistry abnormalities are the consequence of drug toxicity.
Fil: Pirola, Carlos José. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Sookoian, Silvia Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
description Zhang et al. showed that COVID‐19 affected patients’ present liver biochemistry abnormalities, including elevation of aminotransferases, gamma‐glutamyl transferase, and alkaline phosphatase 1. Hence, several possible clinical scenarios in the setting of liver diseases have been postulated. First, patients with chronic liver disease may be more vulnerable to the severe clinical consequences of COVID‐19, including oxygen desaturation and hypoxemia due to severe pneumonia or the cytokine storm 1;2. Second, liver biochemistry abnormalities are the consequence of drug toxicity.
publishDate 2020
dc.date.none.fl_str_mv 2020-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/106197
Pirola, Carlos José; Sookoian, Silvia Cristina; SARS‐CoV‐2 virus and liver expression of host receptors: putative mechanisms of liver involvement in COVID‐19; Wiley Blackwell Publishing, Inc; Liver International; 4-2020; 1-7
1478-3223
CONICET Digital
CONICET
url http://hdl.handle.net/11336/106197
identifier_str_mv Pirola, Carlos José; Sookoian, Silvia Cristina; SARS‐CoV‐2 virus and liver expression of host receptors: putative mechanisms of liver involvement in COVID‐19; Wiley Blackwell Publishing, Inc; Liver International; 4-2020; 1-7
1478-3223
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1111/liv.14500
info:eu-repo/semantics/altIdentifier/doi/10.1111/liv.14500
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.069144

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