Antifungal activity in vitro and in vivo of extracts and lignans isolated from Larrea divaricata Cav. against phytopathogenic fungus

Autores
Vogt, Maria Veronica; Cifuente, Diego Alberto; Tonn, Carlos Eugenio; Sabini, Liliana; Rosas, Susana Beatriz
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The aim of this study was to evaluate the effectiveness of organic extracts and isolated compounds of the medicinal plant Larrea divaricata Cav. against phytopathogenic fungi. Chloroformic extract showed the highest antifungal activity and three compounds were identified in this extract: Apigenine-7-methylether (1), nordihydroguaiaretic acid (2) and 3,4′-dihydroxy-3′,4-dimethoxy-6,7′-cyclolignan (3). Compound 3 is described for the first time in the species and exhibited strong antifungal activity in vitro (Fusarium graminearum MIC = 15.6 μg/mL) and in vivo producing decreasing disease on glasshouse-grown wheat plants reducing damping-off (14% in pre emergency) and Severity Index from 2.6 upto 1.1. In this study it is clear that the application of botanical products from L. divaricata can be effective in the management of seedling blight and crown rot of wheat.
Fil: Vogt, Maria Veronica. Universidad Nacional de Rio Cuarto. Departamento de Quã­mica; Argentina
Fil: Cifuente, Diego Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Investigaciones En Tecnología Química; Argentina
Fil: Tonn, Carlos Eugenio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Investigaciones En Tecnología Química; Argentina
Fil: Sabini, Liliana. Universidad Nacional de Rio Cuarto. Departamento de Quã­mica; Argentina
Fil: Rosas, Susana Beatriz. Universidad Nacional de Rio Cuarto. Departamento de Quã­mica; Argentina
Materia
Antifungal Activity
Chemical Constituents
Larrea Divaricata
Organic Extracts
Phytopathogenic Fungi
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/7398
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Antifungal activity in vitro and in vivo of extracts and lignans isolated from Larrea divaricata Cav. against phytopathogenic fungusVogt, Maria VeronicaCifuente, Diego AlbertoTonn, Carlos EugenioSabini, LilianaRosas, Susana BeatrizAntifungal ActivityChemical ConstituentsLarrea DivaricataOrganic ExtractsPhytopathogenic Fungihttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The aim of this study was to evaluate the effectiveness of organic extracts and isolated compounds of the medicinal plant Larrea divaricata Cav. against phytopathogenic fungi. Chloroformic extract showed the highest antifungal activity and three compounds were identified in this extract: Apigenine-7-methylether (1), nordihydroguaiaretic acid (2) and 3,4′-dihydroxy-3′,4-dimethoxy-6,7′-cyclolignan (3). Compound 3 is described for the first time in the species and exhibited strong antifungal activity in vitro (Fusarium graminearum MIC = 15.6 μg/mL) and in vivo producing decreasing disease on glasshouse-grown wheat plants reducing damping-off (14% in pre emergency) and Severity Index from 2.6 upto 1.1. In this study it is clear that the application of botanical products from L. divaricata can be effective in the management of seedling blight and crown rot of wheat.Fil: Vogt, Maria Veronica. Universidad Nacional de Rio Cuarto. Departamento de Quã­mica; ArgentinaFil: Cifuente, Diego Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Investigaciones En Tecnología Química; ArgentinaFil: Tonn, Carlos Eugenio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Investigaciones En Tecnología Química; ArgentinaFil: Sabini, Liliana. Universidad Nacional de Rio Cuarto. Departamento de Quã­mica; ArgentinaFil: Rosas, Susana Beatriz. Universidad Nacional de Rio Cuarto. Departamento de Quã­mica; ArgentinaElsevier2013-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/7398Vogt, Maria Veronica; Cifuente, Diego Alberto; Tonn, Carlos Eugenio; Sabini, Liliana; Rosas, Susana Beatriz; Antifungal activity in vitro and in vivo of extracts and lignans isolated from Larrea divaricata Cav. against phytopathogenic fungus; Elsevier; Industrial Crops And Products; 42; 3-2013; 583-5860926-6690enginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0926669012003317info:eu-repo/semantics/altIdentifier/doi/10.1016/j.indcrop.2012.06.009info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:54:36Zoai:ri.conicet.gov.ar:11336/7398instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:54:36.775CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Antifungal activity in vitro and in vivo of extracts and lignans isolated from Larrea divaricata Cav. against phytopathogenic fungus
title Antifungal activity in vitro and in vivo of extracts and lignans isolated from Larrea divaricata Cav. against phytopathogenic fungus
spellingShingle Antifungal activity in vitro and in vivo of extracts and lignans isolated from Larrea divaricata Cav. against phytopathogenic fungus
Vogt, Maria Veronica
Antifungal Activity
Chemical Constituents
Larrea Divaricata
Organic Extracts
Phytopathogenic Fungi
title_short Antifungal activity in vitro and in vivo of extracts and lignans isolated from Larrea divaricata Cav. against phytopathogenic fungus
title_full Antifungal activity in vitro and in vivo of extracts and lignans isolated from Larrea divaricata Cav. against phytopathogenic fungus
title_fullStr Antifungal activity in vitro and in vivo of extracts and lignans isolated from Larrea divaricata Cav. against phytopathogenic fungus
title_full_unstemmed Antifungal activity in vitro and in vivo of extracts and lignans isolated from Larrea divaricata Cav. against phytopathogenic fungus
title_sort Antifungal activity in vitro and in vivo of extracts and lignans isolated from Larrea divaricata Cav. against phytopathogenic fungus
dc.creator.none.fl_str_mv Vogt, Maria Veronica
Cifuente, Diego Alberto
Tonn, Carlos Eugenio
Sabini, Liliana
Rosas, Susana Beatriz
author Vogt, Maria Veronica
author_facet Vogt, Maria Veronica
Cifuente, Diego Alberto
Tonn, Carlos Eugenio
Sabini, Liliana
Rosas, Susana Beatriz
author_role author
author2 Cifuente, Diego Alberto
Tonn, Carlos Eugenio
Sabini, Liliana
Rosas, Susana Beatriz
author2_role author
author
author
author
dc.subject.none.fl_str_mv Antifungal Activity
Chemical Constituents
Larrea Divaricata
Organic Extracts
Phytopathogenic Fungi
topic Antifungal Activity
Chemical Constituents
Larrea Divaricata
Organic Extracts
Phytopathogenic Fungi
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The aim of this study was to evaluate the effectiveness of organic extracts and isolated compounds of the medicinal plant Larrea divaricata Cav. against phytopathogenic fungi. Chloroformic extract showed the highest antifungal activity and three compounds were identified in this extract: Apigenine-7-methylether (1), nordihydroguaiaretic acid (2) and 3,4′-dihydroxy-3′,4-dimethoxy-6,7′-cyclolignan (3). Compound 3 is described for the first time in the species and exhibited strong antifungal activity in vitro (Fusarium graminearum MIC = 15.6 μg/mL) and in vivo producing decreasing disease on glasshouse-grown wheat plants reducing damping-off (14% in pre emergency) and Severity Index from 2.6 upto 1.1. In this study it is clear that the application of botanical products from L. divaricata can be effective in the management of seedling blight and crown rot of wheat.
Fil: Vogt, Maria Veronica. Universidad Nacional de Rio Cuarto. Departamento de Quã­mica; Argentina
Fil: Cifuente, Diego Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Investigaciones En Tecnología Química; Argentina
Fil: Tonn, Carlos Eugenio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Investigaciones En Tecnología Química; Argentina
Fil: Sabini, Liliana. Universidad Nacional de Rio Cuarto. Departamento de Quã­mica; Argentina
Fil: Rosas, Susana Beatriz. Universidad Nacional de Rio Cuarto. Departamento de Quã­mica; Argentina
description The aim of this study was to evaluate the effectiveness of organic extracts and isolated compounds of the medicinal plant Larrea divaricata Cav. against phytopathogenic fungi. Chloroformic extract showed the highest antifungal activity and three compounds were identified in this extract: Apigenine-7-methylether (1), nordihydroguaiaretic acid (2) and 3,4′-dihydroxy-3′,4-dimethoxy-6,7′-cyclolignan (3). Compound 3 is described for the first time in the species and exhibited strong antifungal activity in vitro (Fusarium graminearum MIC = 15.6 μg/mL) and in vivo producing decreasing disease on glasshouse-grown wheat plants reducing damping-off (14% in pre emergency) and Severity Index from 2.6 upto 1.1. In this study it is clear that the application of botanical products from L. divaricata can be effective in the management of seedling blight and crown rot of wheat.
publishDate 2013
dc.date.none.fl_str_mv 2013-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/7398
Vogt, Maria Veronica; Cifuente, Diego Alberto; Tonn, Carlos Eugenio; Sabini, Liliana; Rosas, Susana Beatriz; Antifungal activity in vitro and in vivo of extracts and lignans isolated from Larrea divaricata Cav. against phytopathogenic fungus; Elsevier; Industrial Crops And Products; 42; 3-2013; 583-586
0926-6690
url http://hdl.handle.net/11336/7398
identifier_str_mv Vogt, Maria Veronica; Cifuente, Diego Alberto; Tonn, Carlos Eugenio; Sabini, Liliana; Rosas, Susana Beatriz; Antifungal activity in vitro and in vivo of extracts and lignans isolated from Larrea divaricata Cav. against phytopathogenic fungus; Elsevier; Industrial Crops And Products; 42; 3-2013; 583-586
0926-6690
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0926669012003317
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.indcrop.2012.06.009
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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