Chemical derivatization of natural extracts obtained from Larrea divaricata Cav. increase in the antioxidant activity and protein precipitating capacity

Autores
Ortega, Claudia; Favier, Laura Silvina; Cifuente, Diego Alberto
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In the present work modified extracts of Larrea divaricata was obtained bychemical transformations in order to improve the antioxidant activity and theprotein precipitating capacity. Apigenine-7-methylether, quercetin, nordihydroguaiaretic acid, 3,4-dihydroxy-3,4-dimethoxy-6,7-cyclolignan and pcoumaricacid were identified in the methanolic extract by Electron Impact MassSpectrometry (EIMS). Chemically modified extracts were prepared through acidhydrolysis, sulfonylation, O-methylation, O-acylationand C-acylation reactions.Total phenolics and flavonoids contents were determined by spectrophotometricmethods. Antioxidant properties were evaluated by 2,2-diphenyl-1-picrylhydrazyl(DPPH), 2,2′-azinobis(3-ethylbenzthiazoline-6-acid) (ABTS) and ferric ionreducing power. In addition, the protein precipitating capacity was evaluated intwo protein system and significant changes were observed. Methanolic extractcontaining the highest amount of phenolic compounds and flavonoids exhibitedsignificative antioxidant activity. The hydrolyzed methanolic extract increasedtheir antioxidant properties. However, C-acylated and O-acylated methanolicextracts were the most active. In addition, these extracts revealed the highestprotein precipitating capacity in both protein system. In relation to obtainbioproducts, these results show that antioxidant activity and the proteinprecipitating capacity can be increased by chemical modifications of the naturalorganic extracts.
Fil: Ortega, Claudia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; Argentina
Fil: Favier, Laura Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; Argentina
Fil: Cifuente, Diego Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; Argentina
Materia
Larrea divaricata
modified extracts
antioxidant activity
protein precipitating capacity
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/66837
Acceder
id CONICETDig_5693340a697eb539543d315529140fa4
oai_identifier_str oai:ri.conicet.gov.ar:11336/66837
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Chemical derivatization of natural extracts obtained from Larrea divaricata Cav. increase in the antioxidant activity and protein precipitating capacityOrtega, ClaudiaFavier, Laura SilvinaCifuente, Diego AlbertoLarrea divaricatamodified extractsantioxidant activityprotein precipitating capacityhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1In the present work modified extracts of Larrea divaricata was obtained bychemical transformations in order to improve the antioxidant activity and theprotein precipitating capacity. Apigenine-7-methylether, quercetin, nordihydroguaiaretic acid, 3,4-dihydroxy-3,4-dimethoxy-6,7-cyclolignan and pcoumaricacid were identified in the methanolic extract by Electron Impact MassSpectrometry (EIMS). Chemically modified extracts were prepared through acidhydrolysis, sulfonylation, O-methylation, O-acylationand C-acylation reactions.Total phenolics and flavonoids contents were determined by spectrophotometricmethods. Antioxidant properties were evaluated by 2,2-diphenyl-1-picrylhydrazyl(DPPH), 2,2′-azinobis(3-ethylbenzthiazoline-6-acid) (ABTS) and ferric ionreducing power. In addition, the protein precipitating capacity was evaluated intwo protein system and significant changes were observed. Methanolic extractcontaining the highest amount of phenolic compounds and flavonoids exhibitedsignificative antioxidant activity. The hydrolyzed methanolic extract increasedtheir antioxidant properties. However, C-acylated and O-acylated methanolicextracts were the most active. In addition, these extracts revealed the highestprotein precipitating capacity in both protein system. In relation to obtainbioproducts, these results show that antioxidant activity and the proteinprecipitating capacity can be increased by chemical modifications of the naturalorganic extracts.Fil: Ortega, Claudia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; ArgentinaFil: Favier, Laura Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; ArgentinaFil: Cifuente, Diego Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; ArgentinaAcademia Publishing2017-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/66837Ortega, Claudia; Favier, Laura Silvina; Cifuente, Diego Alberto; Chemical derivatization of natural extracts obtained from Larrea divaricata Cav. increase in the antioxidant activity and protein precipitating capacity; Academia Publishing; Academia Journal of Scientific Research; 7; 7-2017; 197-2022315-7712CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.15413/ajsr.2017.0412info:eu-repo/semantics/altIdentifier/url/https://academiapublishing.org/journals/ajsr/abstract/2017/Jul/Ortega%20et%20al.htminfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:33:31Zoai:ri.conicet.gov.ar:11336/66837instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:33:31.367CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Chemical derivatization of natural extracts obtained from Larrea divaricata Cav. increase in the antioxidant activity and protein precipitating capacity
title Chemical derivatization of natural extracts obtained from Larrea divaricata Cav. increase in the antioxidant activity and protein precipitating capacity
spellingShingle Chemical derivatization of natural extracts obtained from Larrea divaricata Cav. increase in the antioxidant activity and protein precipitating capacity
Ortega, Claudia
Larrea divaricata
modified extracts
antioxidant activity
protein precipitating capacity
title_short Chemical derivatization of natural extracts obtained from Larrea divaricata Cav. increase in the antioxidant activity and protein precipitating capacity
title_full Chemical derivatization of natural extracts obtained from Larrea divaricata Cav. increase in the antioxidant activity and protein precipitating capacity
title_fullStr Chemical derivatization of natural extracts obtained from Larrea divaricata Cav. increase in the antioxidant activity and protein precipitating capacity
title_full_unstemmed Chemical derivatization of natural extracts obtained from Larrea divaricata Cav. increase in the antioxidant activity and protein precipitating capacity
title_sort Chemical derivatization of natural extracts obtained from Larrea divaricata Cav. increase in the antioxidant activity and protein precipitating capacity
dc.creator.none.fl_str_mv Ortega, Claudia
Favier, Laura Silvina
Cifuente, Diego Alberto
author Ortega, Claudia
author_facet Ortega, Claudia
Favier, Laura Silvina
Cifuente, Diego Alberto
author_role author
author2 Favier, Laura Silvina
Cifuente, Diego Alberto
author2_role author
author
dc.subject.none.fl_str_mv Larrea divaricata
modified extracts
antioxidant activity
protein precipitating capacity
topic Larrea divaricata
modified extracts
antioxidant activity
protein precipitating capacity
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv In the present work modified extracts of Larrea divaricata was obtained bychemical transformations in order to improve the antioxidant activity and theprotein precipitating capacity. Apigenine-7-methylether, quercetin, nordihydroguaiaretic acid, 3,4-dihydroxy-3,4-dimethoxy-6,7-cyclolignan and pcoumaricacid were identified in the methanolic extract by Electron Impact MassSpectrometry (EIMS). Chemically modified extracts were prepared through acidhydrolysis, sulfonylation, O-methylation, O-acylationand C-acylation reactions.Total phenolics and flavonoids contents were determined by spectrophotometricmethods. Antioxidant properties were evaluated by 2,2-diphenyl-1-picrylhydrazyl(DPPH), 2,2′-azinobis(3-ethylbenzthiazoline-6-acid) (ABTS) and ferric ionreducing power. In addition, the protein precipitating capacity was evaluated intwo protein system and significant changes were observed. Methanolic extractcontaining the highest amount of phenolic compounds and flavonoids exhibitedsignificative antioxidant activity. The hydrolyzed methanolic extract increasedtheir antioxidant properties. However, C-acylated and O-acylated methanolicextracts were the most active. In addition, these extracts revealed the highestprotein precipitating capacity in both protein system. In relation to obtainbioproducts, these results show that antioxidant activity and the proteinprecipitating capacity can be increased by chemical modifications of the naturalorganic extracts.
Fil: Ortega, Claudia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; Argentina
Fil: Favier, Laura Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; Argentina
Fil: Cifuente, Diego Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; Argentina
description In the present work modified extracts of Larrea divaricata was obtained bychemical transformations in order to improve the antioxidant activity and theprotein precipitating capacity. Apigenine-7-methylether, quercetin, nordihydroguaiaretic acid, 3,4-dihydroxy-3,4-dimethoxy-6,7-cyclolignan and pcoumaricacid were identified in the methanolic extract by Electron Impact MassSpectrometry (EIMS). Chemically modified extracts were prepared through acidhydrolysis, sulfonylation, O-methylation, O-acylationand C-acylation reactions.Total phenolics and flavonoids contents were determined by spectrophotometricmethods. Antioxidant properties were evaluated by 2,2-diphenyl-1-picrylhydrazyl(DPPH), 2,2′-azinobis(3-ethylbenzthiazoline-6-acid) (ABTS) and ferric ionreducing power. In addition, the protein precipitating capacity was evaluated intwo protein system and significant changes were observed. Methanolic extractcontaining the highest amount of phenolic compounds and flavonoids exhibitedsignificative antioxidant activity. The hydrolyzed methanolic extract increasedtheir antioxidant properties. However, C-acylated and O-acylated methanolicextracts were the most active. In addition, these extracts revealed the highestprotein precipitating capacity in both protein system. In relation to obtainbioproducts, these results show that antioxidant activity and the proteinprecipitating capacity can be increased by chemical modifications of the naturalorganic extracts.
publishDate 2017
dc.date.none.fl_str_mv 2017-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/66837
Ortega, Claudia; Favier, Laura Silvina; Cifuente, Diego Alberto; Chemical derivatization of natural extracts obtained from Larrea divaricata Cav. increase in the antioxidant activity and protein precipitating capacity; Academia Publishing; Academia Journal of Scientific Research; 7; 7-2017; 197-202
2315-7712
CONICET Digital
CONICET
url http://hdl.handle.net/11336/66837
identifier_str_mv Ortega, Claudia; Favier, Laura Silvina; Cifuente, Diego Alberto; Chemical derivatization of natural extracts obtained from Larrea divaricata Cav. increase in the antioxidant activity and protein precipitating capacity; Academia Publishing; Academia Journal of Scientific Research; 7; 7-2017; 197-202
2315-7712
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.15413/ajsr.2017.0412
info:eu-repo/semantics/altIdentifier/url/https://academiapublishing.org/journals/ajsr/abstract/2017/Jul/Ortega%20et%20al.htm
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Academia Publishing
publisher.none.fl_str_mv Academia Publishing
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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