Epstein Barr Virus (EBV) Association and Latency Profile in Paediatric Burkitt Lymphoma: Experience of a Single Institution in Argentina

Autores
Lara, María Julia; Cohen, Melina; de Matteo, Elena Noemí; Aversa, Luis; Preciado, María Victoria; Chabay, Paola Andrea
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The aim of this study is to characterise EBV expression and latency pattern in paediatric Burkitt lymphoma in a single institution in Argentina. EBV-encoded RNA or protein was analyzed in 27 patients. EBERs was expressed in 37% of patients (29% of immunocompetent and 100% of immunosuppressed patients). EBV-positive cases were observed exclusively in patients younger than 5 years old. EBV association with immunocompetent patients exhibits the sporadic pattern in region under study, while its presence in patients infected with HIV was higher than described previously. EBV latency I profile was present in most of the patients, except for 2 immunosuppressed patients who displayed LMP1 expression.
Fil: Lara, María Julia. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Cohen, Melina. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: de Matteo, Elena Noemí. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Aversa, Luis. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Preciado, María Victoria. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Chabay, Paola Andrea. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Bhrf1
Ebv
Lmp1
Childhood
Latency
Lymphoma
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/33488
Acceder
id CONICETDig_77407196b37fb8cb413541c9a3f5a42b
oai_identifier_str oai:ri.conicet.gov.ar:11336/33488
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Epstein Barr Virus (EBV) Association and Latency Profile in Paediatric Burkitt Lymphoma: Experience of a Single Institution in ArgentinaLara, María JuliaCohen, Melinade Matteo, Elena NoemíAversa, LuisPreciado, María VictoriaChabay, Paola AndreaBhrf1EbvLmp1ChildhoodLatencyLymphomahttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3The aim of this study is to characterise EBV expression and latency pattern in paediatric Burkitt lymphoma in a single institution in Argentina. EBV-encoded RNA or protein was analyzed in 27 patients. EBERs was expressed in 37% of patients (29% of immunocompetent and 100% of immunosuppressed patients). EBV-positive cases were observed exclusively in patients younger than 5 years old. EBV association with immunocompetent patients exhibits the sporadic pattern in region under study, while its presence in patients infected with HIV was higher than described previously. EBV latency I profile was present in most of the patients, except for 2 immunosuppressed patients who displayed LMP1 expression.Fil: Lara, María Julia. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Cohen, Melina. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: de Matteo, Elena Noemí. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Aversa, Luis. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Preciado, María Victoria. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Chabay, Paola Andrea. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaWiley2013-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/33488de Matteo, Elena Noemí; Lara, María Julia; Preciado, María Victoria; Cohen, Melina; Chabay, Paola Andrea; Aversa, Luis; et al.; Epstein Barr Virus (EBV) Association and Latency Profile in Paediatric Burkitt Lymphoma: Experience of a Single Institution in Argentina; Wiley; Journal of Medical Virology; 86; 5; 9-2013; 845-8500146-6615CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/jmv.23737/abstractinfo:eu-repo/semantics/altIdentifier/doi/10.1002/jmv.23737info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:21:19Zoai:ri.conicet.gov.ar:11336/33488instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:21:19.534CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Epstein Barr Virus (EBV) Association and Latency Profile in Paediatric Burkitt Lymphoma: Experience of a Single Institution in Argentina
title Epstein Barr Virus (EBV) Association and Latency Profile in Paediatric Burkitt Lymphoma: Experience of a Single Institution in Argentina
spellingShingle Epstein Barr Virus (EBV) Association and Latency Profile in Paediatric Burkitt Lymphoma: Experience of a Single Institution in Argentina
Lara, María Julia
Bhrf1
Ebv
Lmp1
Childhood
Latency
Lymphoma
title_short Epstein Barr Virus (EBV) Association and Latency Profile in Paediatric Burkitt Lymphoma: Experience of a Single Institution in Argentina
title_full Epstein Barr Virus (EBV) Association and Latency Profile in Paediatric Burkitt Lymphoma: Experience of a Single Institution in Argentina
title_fullStr Epstein Barr Virus (EBV) Association and Latency Profile in Paediatric Burkitt Lymphoma: Experience of a Single Institution in Argentina
title_full_unstemmed Epstein Barr Virus (EBV) Association and Latency Profile in Paediatric Burkitt Lymphoma: Experience of a Single Institution in Argentina
title_sort Epstein Barr Virus (EBV) Association and Latency Profile in Paediatric Burkitt Lymphoma: Experience of a Single Institution in Argentina
dc.creator.none.fl_str_mv Lara, María Julia
Cohen, Melina
de Matteo, Elena Noemí
Aversa, Luis
Preciado, María Victoria
Chabay, Paola Andrea
author Lara, María Julia
author_facet Lara, María Julia
Cohen, Melina
de Matteo, Elena Noemí
Aversa, Luis
Preciado, María Victoria
Chabay, Paola Andrea
author_role author
author2 Cohen, Melina
de Matteo, Elena Noemí
Aversa, Luis
Preciado, María Victoria
Chabay, Paola Andrea
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Bhrf1
Ebv
Lmp1
Childhood
Latency
Lymphoma
topic Bhrf1
Ebv
Lmp1
Childhood
Latency
Lymphoma
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The aim of this study is to characterise EBV expression and latency pattern in paediatric Burkitt lymphoma in a single institution in Argentina. EBV-encoded RNA or protein was analyzed in 27 patients. EBERs was expressed in 37% of patients (29% of immunocompetent and 100% of immunosuppressed patients). EBV-positive cases were observed exclusively in patients younger than 5 years old. EBV association with immunocompetent patients exhibits the sporadic pattern in region under study, while its presence in patients infected with HIV was higher than described previously. EBV latency I profile was present in most of the patients, except for 2 immunosuppressed patients who displayed LMP1 expression.
Fil: Lara, María Julia. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Cohen, Melina. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: de Matteo, Elena Noemí. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Aversa, Luis. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Preciado, María Victoria. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Chabay, Paola Andrea. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description The aim of this study is to characterise EBV expression and latency pattern in paediatric Burkitt lymphoma in a single institution in Argentina. EBV-encoded RNA or protein was analyzed in 27 patients. EBERs was expressed in 37% of patients (29% of immunocompetent and 100% of immunosuppressed patients). EBV-positive cases were observed exclusively in patients younger than 5 years old. EBV association with immunocompetent patients exhibits the sporadic pattern in region under study, while its presence in patients infected with HIV was higher than described previously. EBV latency I profile was present in most of the patients, except for 2 immunosuppressed patients who displayed LMP1 expression.
publishDate 2013
dc.date.none.fl_str_mv 2013-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/33488
de Matteo, Elena Noemí; Lara, María Julia; Preciado, María Victoria; Cohen, Melina; Chabay, Paola Andrea; Aversa, Luis; et al.; Epstein Barr Virus (EBV) Association and Latency Profile in Paediatric Burkitt Lymphoma: Experience of a Single Institution in Argentina; Wiley; Journal of Medical Virology; 86; 5; 9-2013; 845-850
0146-6615
CONICET Digital
CONICET
url http://hdl.handle.net/11336/33488
identifier_str_mv de Matteo, Elena Noemí; Lara, María Julia; Preciado, María Victoria; Cohen, Melina; Chabay, Paola Andrea; Aversa, Luis; et al.; Epstein Barr Virus (EBV) Association and Latency Profile in Paediatric Burkitt Lymphoma: Experience of a Single Institution in Argentina; Wiley; Journal of Medical Virology; 86; 5; 9-2013; 845-850
0146-6615
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/jmv.23737/abstract
info:eu-repo/semantics/altIdentifier/doi/10.1002/jmv.23737
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846083361789968384
score 13.22299

Publicaciones similares