Fabrication of ferrogels using different magnetic nanoparticles and their performance on protein adsorption

Autores
Gonzalez, Jimena Soledad; Nicolás, Paula; Ferreira, Maria Lujan; Avena, Marcelo Javier; Lassalle, Verónica Leticia; Alvarez, Vera Alejandra
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Magnetic biomaterials were prepared using magnetite and chitosan-coated magnetite nanoparticles (CSNPs) dispersed in poly(vinyl alcohol) gels. Two different methods were developed to obtain ferrogels: in situ co-precipitation of magnetite (Ferro-IS) and by adding previously synthesized CSNPs to the neat matrix (Ferro-CSNPs). In both cases, the crosslinking was carried out by freezing −thawing (F-T). The as-prepared materials as well as precursor CSNPs were characterized by Fourier transform infrared spectroscopy, electronic microscopy (scanning and transmission), X-ray diffraction, ζ potential, dynamic light scattering, thermogravimetric analysis, differential scanning calorimetry and magnetic properties. The performance of these gels as protein adsorbents was evaluated. Batch adsorption experiments were carried out using bovine serum albumin (BSA) as a model. Substantially different adsorption behaviour was found using Ferro-IS and Ferro-CSNPs. This was assigned to dissimilar bonding mechanisms of BSA to the ferrogel matrix. Hence, biomaterials potentially useful in drug delivery as well as in protein purification fields may be prepared by a relatively simple, non-toxic and low cost method.
Fil: Gonzalez, Jimena Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina
Fil: Nicolás, Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Química del Sur; Argentina
Fil: Ferreira, Maria Lujan. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Planta Piloto de Ingeniería Química (i); Argentina
Fil: Avena, Marcelo Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Química del Sur; Argentina
Fil: Lassalle, Verónica Leticia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Química del Sur; Argentina
Fil: Alvarez, Vera Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina
Materia
ADSORPTION
BIOMATERIALS
FERROGEL
IRON OXIDES
MAGNETIC MATERIALS
PROTEIN
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/4093
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/4093
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Fabrication of ferrogels using different magnetic nanoparticles and their performance on protein adsorptionGonzalez, Jimena SoledadNicolás, PaulaFerreira, Maria LujanAvena, Marcelo JavierLassalle, Verónica LeticiaAlvarez, Vera AlejandraADSORPTIONBIOMATERIALSFERROGELIRON OXIDESMAGNETIC MATERIALSPROTEINhttps://purl.org/becyt/ford/2.10https://purl.org/becyt/ford/2https://purl.org/becyt/ford/2.9https://purl.org/becyt/ford/2Magnetic biomaterials were prepared using magnetite and chitosan-coated magnetite nanoparticles (CSNPs) dispersed in poly(vinyl alcohol) gels. Two different methods were developed to obtain ferrogels: in situ co-precipitation of magnetite (Ferro-IS) and by adding previously synthesized CSNPs to the neat matrix (Ferro-CSNPs). In both cases, the crosslinking was carried out by freezing −thawing (F-T). The as-prepared materials as well as precursor CSNPs were characterized by Fourier transform infrared spectroscopy, electronic microscopy (scanning and transmission), X-ray diffraction, ζ potential, dynamic light scattering, thermogravimetric analysis, differential scanning calorimetry and magnetic properties. The performance of these gels as protein adsorbents was evaluated. Batch adsorption experiments were carried out using bovine serum albumin (BSA) as a model. Substantially different adsorption behaviour was found using Ferro-IS and Ferro-CSNPs. This was assigned to dissimilar bonding mechanisms of BSA to the ferrogel matrix. Hence, biomaterials potentially useful in drug delivery as well as in protein purification fields may be prepared by a relatively simple, non-toxic and low cost method.Fil: Gonzalez, Jimena Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); ArgentinaFil: Nicolás, Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Química del Sur; ArgentinaFil: Ferreira, Maria Lujan. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Planta Piloto de Ingeniería Química (i); ArgentinaFil: Avena, Marcelo Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Química del Sur; ArgentinaFil: Lassalle, Verónica Leticia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Química del Sur; ArgentinaFil: Alvarez, Vera Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); ArgentinaJohn Wiley & Sons Ltd2013-04-26info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/4093Gonzalez, Jimena Soledad; Nicolás, Paula; Ferreira, Maria Lujan; Avena, Marcelo Javier; Lassalle, Verónica Leticia; et al.; Fabrication of ferrogels using different magnetic nanoparticles and their performance on protein adsorption; John Wiley & Sons Ltd; Polymer International; 63; 2; 26-4-2013; 258-2650959-8103enginfo:eu-repo/semantics/altIdentifier/doi/10.1002/pi.4498info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/pi.4498/abstractinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:12:03Zoai:ri.conicet.gov.ar:11336/4093instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:12:04.049CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Fabrication of ferrogels using different magnetic nanoparticles and their performance on protein adsorption
title Fabrication of ferrogels using different magnetic nanoparticles and their performance on protein adsorption
spellingShingle Fabrication of ferrogels using different magnetic nanoparticles and their performance on protein adsorption
Gonzalez, Jimena Soledad
ADSORPTION
BIOMATERIALS
FERROGEL
IRON OXIDES
MAGNETIC MATERIALS
PROTEIN
title_short Fabrication of ferrogels using different magnetic nanoparticles and their performance on protein adsorption
title_full Fabrication of ferrogels using different magnetic nanoparticles and their performance on protein adsorption
title_fullStr Fabrication of ferrogels using different magnetic nanoparticles and their performance on protein adsorption
title_full_unstemmed Fabrication of ferrogels using different magnetic nanoparticles and their performance on protein adsorption
title_sort Fabrication of ferrogels using different magnetic nanoparticles and their performance on protein adsorption
dc.creator.none.fl_str_mv Gonzalez, Jimena Soledad
Nicolás, Paula
Ferreira, Maria Lujan
Avena, Marcelo Javier
Lassalle, Verónica Leticia
Alvarez, Vera Alejandra
author Gonzalez, Jimena Soledad
author_facet Gonzalez, Jimena Soledad
Nicolás, Paula
Ferreira, Maria Lujan
Avena, Marcelo Javier
Lassalle, Verónica Leticia
Alvarez, Vera Alejandra
author_role author
author2 Nicolás, Paula
Ferreira, Maria Lujan
Avena, Marcelo Javier
Lassalle, Verónica Leticia
Alvarez, Vera Alejandra
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv ADSORPTION
BIOMATERIALS
FERROGEL
IRON OXIDES
MAGNETIC MATERIALS
PROTEIN
topic ADSORPTION
BIOMATERIALS
FERROGEL
IRON OXIDES
MAGNETIC MATERIALS
PROTEIN
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.10
https://purl.org/becyt/ford/2
https://purl.org/becyt/ford/2.9
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Magnetic biomaterials were prepared using magnetite and chitosan-coated magnetite nanoparticles (CSNPs) dispersed in poly(vinyl alcohol) gels. Two different methods were developed to obtain ferrogels: in situ co-precipitation of magnetite (Ferro-IS) and by adding previously synthesized CSNPs to the neat matrix (Ferro-CSNPs). In both cases, the crosslinking was carried out by freezing −thawing (F-T). The as-prepared materials as well as precursor CSNPs were characterized by Fourier transform infrared spectroscopy, electronic microscopy (scanning and transmission), X-ray diffraction, ζ potential, dynamic light scattering, thermogravimetric analysis, differential scanning calorimetry and magnetic properties. The performance of these gels as protein adsorbents was evaluated. Batch adsorption experiments were carried out using bovine serum albumin (BSA) as a model. Substantially different adsorption behaviour was found using Ferro-IS and Ferro-CSNPs. This was assigned to dissimilar bonding mechanisms of BSA to the ferrogel matrix. Hence, biomaterials potentially useful in drug delivery as well as in protein purification fields may be prepared by a relatively simple, non-toxic and low cost method.
Fil: Gonzalez, Jimena Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina
Fil: Nicolás, Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Química del Sur; Argentina
Fil: Ferreira, Maria Lujan. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Planta Piloto de Ingeniería Química (i); Argentina
Fil: Avena, Marcelo Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Química del Sur; Argentina
Fil: Lassalle, Verónica Leticia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Química del Sur; Argentina
Fil: Alvarez, Vera Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina
description Magnetic biomaterials were prepared using magnetite and chitosan-coated magnetite nanoparticles (CSNPs) dispersed in poly(vinyl alcohol) gels. Two different methods were developed to obtain ferrogels: in situ co-precipitation of magnetite (Ferro-IS) and by adding previously synthesized CSNPs to the neat matrix (Ferro-CSNPs). In both cases, the crosslinking was carried out by freezing −thawing (F-T). The as-prepared materials as well as precursor CSNPs were characterized by Fourier transform infrared spectroscopy, electronic microscopy (scanning and transmission), X-ray diffraction, ζ potential, dynamic light scattering, thermogravimetric analysis, differential scanning calorimetry and magnetic properties. The performance of these gels as protein adsorbents was evaluated. Batch adsorption experiments were carried out using bovine serum albumin (BSA) as a model. Substantially different adsorption behaviour was found using Ferro-IS and Ferro-CSNPs. This was assigned to dissimilar bonding mechanisms of BSA to the ferrogel matrix. Hence, biomaterials potentially useful in drug delivery as well as in protein purification fields may be prepared by a relatively simple, non-toxic and low cost method.
publishDate 2013
dc.date.none.fl_str_mv 2013-04-26
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/4093
Gonzalez, Jimena Soledad; Nicolás, Paula; Ferreira, Maria Lujan; Avena, Marcelo Javier; Lassalle, Verónica Leticia; et al.; Fabrication of ferrogels using different magnetic nanoparticles and their performance on protein adsorption; John Wiley & Sons Ltd; Polymer International; 63; 2; 26-4-2013; 258-265
0959-8103
url http://hdl.handle.net/11336/4093
identifier_str_mv Gonzalez, Jimena Soledad; Nicolás, Paula; Ferreira, Maria Lujan; Avena, Marcelo Javier; Lassalle, Verónica Leticia; et al.; Fabrication of ferrogels using different magnetic nanoparticles and their performance on protein adsorption; John Wiley & Sons Ltd; Polymer International; 63; 2; 26-4-2013; 258-265
0959-8103
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1002/pi.4498
info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/pi.4498/abstract
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv John Wiley & Sons Ltd
publisher.none.fl_str_mv John Wiley & Sons Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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