A simple and efficient procedure for the synthesis of ferrogels based on physically cross-linked PVA

Autores
Gonzalez, Jimena Soledad; Hoppe, Cristina Elena; Mendoza Zélis, Pedro; Arciniegas Vaca, Magda Lorena; Pasquevich, Gustavo Alberto; Sanchez, Francisco Homero; Alvarez, Vera Alejandra
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Ferrogels with well-dispersed single-domain magnetic nanoparticles (NPs) were obtained by the infusion of iron salts in physically cross-linked poly(vinyl alcohol) (PVA) hydrogels followed by coprecipitation. Freeze-thaw (F-T) cycling was used as a cryogenic technique to form mechanically strong and highly swellable hydrogels. The networked structure of the final material was used as a constrained environment for the precipitation of iron oxide NPs and formation of the magnetic gel. A homogeneous, single-domain ensemble of more than 15 wt % iron oxide NPs (in only one cycle of absorption) could be obtained through this easy technique. Moreover, the capacity of these magnetic ferrogels to absorb high amounts of ethanol/water solutions allows impregnation of these materials with ibuprofen and subsequent release of the drug at physiological pH. The biocompatibility of the components and the use of the nontoxic PVA cross-linking strategy (F-T cycling) make these materials promising for drug-delivery applications.
Fil: Gonzalez, Jimena Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingenieria; Argentina
Fil: Hoppe, Cristina Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingenieria; Argentina
Fil: Mendoza Zélis, Pedro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Instituto de Física La Plata; Argentina
Fil: Arciniegas Vaca, Magda Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Instituto de Física La Plata; Argentina
Fil: Pasquevich, Gustavo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Instituto de Física La Plata; Argentina
Fil: Sanchez, Francisco Homero. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Instituto de Física La Plata; Argentina
Fil: Alvarez, Vera Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingenieria; Argentina
Materia
Ferrogel
Freezing Thawing
Magnetic Properties
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/2603
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/2603
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling A simple and efficient procedure for the synthesis of ferrogels based on physically cross-linked PVAGonzalez, Jimena SoledadHoppe, Cristina ElenaMendoza Zélis, PedroArciniegas Vaca, Magda LorenaPasquevich, Gustavo AlbertoSanchez, Francisco HomeroAlvarez, Vera AlejandraFerrogelFreezing ThawingMagnetic Propertieshttps://purl.org/becyt/ford/2.5https://purl.org/becyt/ford/2https://purl.org/becyt/ford/2.10https://purl.org/becyt/ford/2Ferrogels with well-dispersed single-domain magnetic nanoparticles (NPs) were obtained by the infusion of iron salts in physically cross-linked poly(vinyl alcohol) (PVA) hydrogels followed by coprecipitation. Freeze-thaw (F-T) cycling was used as a cryogenic technique to form mechanically strong and highly swellable hydrogels. The networked structure of the final material was used as a constrained environment for the precipitation of iron oxide NPs and formation of the magnetic gel. A homogeneous, single-domain ensemble of more than 15 wt % iron oxide NPs (in only one cycle of absorption) could be obtained through this easy technique. Moreover, the capacity of these magnetic ferrogels to absorb high amounts of ethanol/water solutions allows impregnation of these materials with ibuprofen and subsequent release of the drug at physiological pH. The biocompatibility of the components and the use of the nontoxic PVA cross-linking strategy (F-T cycling) make these materials promising for drug-delivery applications.Fil: Gonzalez, Jimena Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingenieria; ArgentinaFil: Hoppe, Cristina Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingenieria; ArgentinaFil: Mendoza Zélis, Pedro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Instituto de Física La Plata; ArgentinaFil: Arciniegas Vaca, Magda Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Instituto de Física La Plata; ArgentinaFil: Pasquevich, Gustavo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Instituto de Física La Plata; ArgentinaFil: Sanchez, Francisco Homero. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Instituto de Física La Plata; ArgentinaFil: Alvarez, Vera Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingenieria; ArgentinaAmerican Chemical Society2013-11-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/2603Gonzalez, Jimena Soledad; Hoppe, Cristina Elena; Mendoza Zélis, Pedro; Arciniegas Vaca, Magda Lorena; Pasquevich, Gustavo Alberto; et al.; A simple and efficient procedure for the synthesis of ferrogels based on physically cross-linked PVA; American Chemical Society; Industrial & Engineering Chemical Research; 53; 1; 29-11-2013; 214-2210888-5885enginfo:eu-repo/semantics/altIdentifier/url/http://pubs.acs.org/doi/abs/10.1021/ie402652jinfo:eu-repo/semantics/altIdentifier/doi/10.1021/ie402652jinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:11:03Zoai:ri.conicet.gov.ar:11336/2603instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:11:03.555CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv A simple and efficient procedure for the synthesis of ferrogels based on physically cross-linked PVA
title A simple and efficient procedure for the synthesis of ferrogels based on physically cross-linked PVA
spellingShingle A simple and efficient procedure for the synthesis of ferrogels based on physically cross-linked PVA
Gonzalez, Jimena Soledad
Ferrogel
Freezing Thawing
Magnetic Properties
title_short A simple and efficient procedure for the synthesis of ferrogels based on physically cross-linked PVA
title_full A simple and efficient procedure for the synthesis of ferrogels based on physically cross-linked PVA
title_fullStr A simple and efficient procedure for the synthesis of ferrogels based on physically cross-linked PVA
title_full_unstemmed A simple and efficient procedure for the synthesis of ferrogels based on physically cross-linked PVA
title_sort A simple and efficient procedure for the synthesis of ferrogels based on physically cross-linked PVA
dc.creator.none.fl_str_mv Gonzalez, Jimena Soledad
Hoppe, Cristina Elena
Mendoza Zélis, Pedro
Arciniegas Vaca, Magda Lorena
Pasquevich, Gustavo Alberto
Sanchez, Francisco Homero
Alvarez, Vera Alejandra
author Gonzalez, Jimena Soledad
author_facet Gonzalez, Jimena Soledad
Hoppe, Cristina Elena
Mendoza Zélis, Pedro
Arciniegas Vaca, Magda Lorena
Pasquevich, Gustavo Alberto
Sanchez, Francisco Homero
Alvarez, Vera Alejandra
author_role author
author2 Hoppe, Cristina Elena
Mendoza Zélis, Pedro
Arciniegas Vaca, Magda Lorena
Pasquevich, Gustavo Alberto
Sanchez, Francisco Homero
Alvarez, Vera Alejandra
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Ferrogel
Freezing Thawing
Magnetic Properties
topic Ferrogel
Freezing Thawing
Magnetic Properties
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
https://purl.org/becyt/ford/2.10
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Ferrogels with well-dispersed single-domain magnetic nanoparticles (NPs) were obtained by the infusion of iron salts in physically cross-linked poly(vinyl alcohol) (PVA) hydrogels followed by coprecipitation. Freeze-thaw (F-T) cycling was used as a cryogenic technique to form mechanically strong and highly swellable hydrogels. The networked structure of the final material was used as a constrained environment for the precipitation of iron oxide NPs and formation of the magnetic gel. A homogeneous, single-domain ensemble of more than 15 wt % iron oxide NPs (in only one cycle of absorption) could be obtained through this easy technique. Moreover, the capacity of these magnetic ferrogels to absorb high amounts of ethanol/water solutions allows impregnation of these materials with ibuprofen and subsequent release of the drug at physiological pH. The biocompatibility of the components and the use of the nontoxic PVA cross-linking strategy (F-T cycling) make these materials promising for drug-delivery applications.
Fil: Gonzalez, Jimena Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingenieria; Argentina
Fil: Hoppe, Cristina Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingenieria; Argentina
Fil: Mendoza Zélis, Pedro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Instituto de Física La Plata; Argentina
Fil: Arciniegas Vaca, Magda Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Instituto de Física La Plata; Argentina
Fil: Pasquevich, Gustavo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Instituto de Física La Plata; Argentina
Fil: Sanchez, Francisco Homero. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Instituto de Física La Plata; Argentina
Fil: Alvarez, Vera Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingenieria; Argentina
description Ferrogels with well-dispersed single-domain magnetic nanoparticles (NPs) were obtained by the infusion of iron salts in physically cross-linked poly(vinyl alcohol) (PVA) hydrogels followed by coprecipitation. Freeze-thaw (F-T) cycling was used as a cryogenic technique to form mechanically strong and highly swellable hydrogels. The networked structure of the final material was used as a constrained environment for the precipitation of iron oxide NPs and formation of the magnetic gel. A homogeneous, single-domain ensemble of more than 15 wt % iron oxide NPs (in only one cycle of absorption) could be obtained through this easy technique. Moreover, the capacity of these magnetic ferrogels to absorb high amounts of ethanol/water solutions allows impregnation of these materials with ibuprofen and subsequent release of the drug at physiological pH. The biocompatibility of the components and the use of the nontoxic PVA cross-linking strategy (F-T cycling) make these materials promising for drug-delivery applications.
publishDate 2013
dc.date.none.fl_str_mv 2013-11-29
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/2603
Gonzalez, Jimena Soledad; Hoppe, Cristina Elena; Mendoza Zélis, Pedro; Arciniegas Vaca, Magda Lorena; Pasquevich, Gustavo Alberto; et al.; A simple and efficient procedure for the synthesis of ferrogels based on physically cross-linked PVA; American Chemical Society; Industrial & Engineering Chemical Research; 53; 1; 29-11-2013; 214-221
0888-5885
url http://hdl.handle.net/11336/2603
identifier_str_mv Gonzalez, Jimena Soledad; Hoppe, Cristina Elena; Mendoza Zélis, Pedro; Arciniegas Vaca, Magda Lorena; Pasquevich, Gustavo Alberto; et al.; A simple and efficient procedure for the synthesis of ferrogels based on physically cross-linked PVA; American Chemical Society; Industrial & Engineering Chemical Research; 53; 1; 29-11-2013; 214-221
0888-5885
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://pubs.acs.org/doi/abs/10.1021/ie402652j
info:eu-repo/semantics/altIdentifier/doi/10.1021/ie402652j
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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