Early development of mast cell system in lingual tissues of intrauterine and newborn rats

Autores
Zavala, Walther David; Foscolo, Mabel Rosa; Davila, J.; Cavicchia, Juan Carlos
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Mast cells (MC) are predominantly localized at the interface between host and environment such as skin and mucosal surfaces. They are able to perceive a variety of allergens and invading pathogens. In oral tissues, degranulation of mast cells has been a consistent feature of inflammatory lesion like liquen planus, gingivitis, periapical process and tumoral responsive. The aim of the present study is to describe the morphology and to establish the homing time in the tongue?s connective tissue of rats. Tongue sections were collected from Wistar rats processed and included in paraffin wax, cut and stained with toluide blue and alcian blue-safranin and immunoenzyme staining procedure with Monoclonal Antibody to mast cell Tryptase. The total number of mast cells was counted and the area was measured to estimate the population density (mm2) and the individual cell morphology. Results showed morphology changes and a series of variations between the first and the second week samples after birth (p?®0.001), but there were not changes between intrauterus and newborn period. Mast cells weredetected from the fifteenth day of intrauterine life in closed relation with skeletal muscle cells. These data suggest a quick MT adaptation and a strategic location that allow them to react against different oral antigens. More studies are going to be necessary to elucidate this phenomenon.
Fil: Zavala, Walther David. Universidad Nacional de Cuyo. Facultad de Odontologia; Argentina
Fil: Foscolo, Mabel Rosa. Consejo Nacional de Investigaciones Cientií­ficas y Tecnicas. Centro Cientifico Tecnologico Mendoza. Instituto Histologia y Embriologia de Mendoza "Dr. M. Burgos"; Argentina
Fil: Davila, J.. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina
Fil: Cavicchia, Juan Carlos. Consejo Nacional de Investigaciones Cientií­ficas y Tecnicas. Centro Cientifico Tecnologico Mendoza. Instituto Histologia y Embriologia de Mendoza "Dr. M. Burgos"; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina
Materia
Mast Cell
Lingual Tissues
Early Development
Intrauterine And Newborn Rats
Tongue
Oral Immunity
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/9847
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/9847
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Early development of mast cell system in lingual tissues of intrauterine and newborn ratsZavala, Walther DavidFoscolo, Mabel RosaDavila, J.Cavicchia, Juan CarlosMast CellLingual TissuesEarly DevelopmentIntrauterine And Newborn RatsTongueOral Immunityhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Mast cells (MC) are predominantly localized at the interface between host and environment such as skin and mucosal surfaces. They are able to perceive a variety of allergens and invading pathogens. In oral tissues, degranulation of mast cells has been a consistent feature of inflammatory lesion like liquen planus, gingivitis, periapical process and tumoral responsive. The aim of the present study is to describe the morphology and to establish the homing time in the tongue?s connective tissue of rats. Tongue sections were collected from Wistar rats processed and included in paraffin wax, cut and stained with toluide blue and alcian blue-safranin and immunoenzyme staining procedure with Monoclonal Antibody to mast cell Tryptase. The total number of mast cells was counted and the area was measured to estimate the population density (mm2) and the individual cell morphology. Results showed morphology changes and a series of variations between the first and the second week samples after birth (p?®0.001), but there were not changes between intrauterus and newborn period. Mast cells weredetected from the fifteenth day of intrauterine life in closed relation with skeletal muscle cells. These data suggest a quick MT adaptation and a strategic location that allow them to react against different oral antigens. More studies are going to be necessary to elucidate this phenomenon.Fil: Zavala, Walther David. Universidad Nacional de Cuyo. Facultad de Odontologia; ArgentinaFil: Foscolo, Mabel Rosa. Consejo Nacional de Investigaciones Cientií­ficas y Tecnicas. Centro Cientifico Tecnologico Mendoza. Instituto Histologia y Embriologia de Mendoza "Dr. M. Burgos"; ArgentinaFil: Davila, J.. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; ArgentinaFil: Cavicchia, Juan Carlos. Consejo Nacional de Investigaciones Cientií­ficas y Tecnicas. Centro Cientifico Tecnologico Mendoza. Instituto Histologia y Embriologia de Mendoza "Dr. M. Burgos"; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; ArgentinaInternational Journal of Sciences2013-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/9847Zavala, Walther David; Foscolo, Mabel Rosa; Davila, J.; Cavicchia, Juan Carlos; Early development of mast cell system in lingual tissues of intrauterine and newborn rats; International Journal of Sciences; International Journal of Sciences; 2; 9; 9-2013; 86-892410-44772305-3925enginfo:eu-repo/semantics/altIdentifier/url/http://www.ijsciences.com/pub/article/264info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:52:28Zoai:ri.conicet.gov.ar:11336/9847instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:52:28.914CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Early development of mast cell system in lingual tissues of intrauterine and newborn rats
title Early development of mast cell system in lingual tissues of intrauterine and newborn rats
spellingShingle Early development of mast cell system in lingual tissues of intrauterine and newborn rats
Zavala, Walther David
Mast Cell
Lingual Tissues
Early Development
Intrauterine And Newborn Rats
Tongue
Oral Immunity
title_short Early development of mast cell system in lingual tissues of intrauterine and newborn rats
title_full Early development of mast cell system in lingual tissues of intrauterine and newborn rats
title_fullStr Early development of mast cell system in lingual tissues of intrauterine and newborn rats
title_full_unstemmed Early development of mast cell system in lingual tissues of intrauterine and newborn rats
title_sort Early development of mast cell system in lingual tissues of intrauterine and newborn rats
dc.creator.none.fl_str_mv Zavala, Walther David
Foscolo, Mabel Rosa
Davila, J.
Cavicchia, Juan Carlos
author Zavala, Walther David
author_facet Zavala, Walther David
Foscolo, Mabel Rosa
Davila, J.
Cavicchia, Juan Carlos
author_role author
author2 Foscolo, Mabel Rosa
Davila, J.
Cavicchia, Juan Carlos
author2_role author
author
author
dc.subject.none.fl_str_mv Mast Cell
Lingual Tissues
Early Development
Intrauterine And Newborn Rats
Tongue
Oral Immunity
topic Mast Cell
Lingual Tissues
Early Development
Intrauterine And Newborn Rats
Tongue
Oral Immunity
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Mast cells (MC) are predominantly localized at the interface between host and environment such as skin and mucosal surfaces. They are able to perceive a variety of allergens and invading pathogens. In oral tissues, degranulation of mast cells has been a consistent feature of inflammatory lesion like liquen planus, gingivitis, periapical process and tumoral responsive. The aim of the present study is to describe the morphology and to establish the homing time in the tongue?s connective tissue of rats. Tongue sections were collected from Wistar rats processed and included in paraffin wax, cut and stained with toluide blue and alcian blue-safranin and immunoenzyme staining procedure with Monoclonal Antibody to mast cell Tryptase. The total number of mast cells was counted and the area was measured to estimate the population density (mm2) and the individual cell morphology. Results showed morphology changes and a series of variations between the first and the second week samples after birth (p?®0.001), but there were not changes between intrauterus and newborn period. Mast cells weredetected from the fifteenth day of intrauterine life in closed relation with skeletal muscle cells. These data suggest a quick MT adaptation and a strategic location that allow them to react against different oral antigens. More studies are going to be necessary to elucidate this phenomenon.
Fil: Zavala, Walther David. Universidad Nacional de Cuyo. Facultad de Odontologia; Argentina
Fil: Foscolo, Mabel Rosa. Consejo Nacional de Investigaciones Cientií­ficas y Tecnicas. Centro Cientifico Tecnologico Mendoza. Instituto Histologia y Embriologia de Mendoza "Dr. M. Burgos"; Argentina
Fil: Davila, J.. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina
Fil: Cavicchia, Juan Carlos. Consejo Nacional de Investigaciones Cientií­ficas y Tecnicas. Centro Cientifico Tecnologico Mendoza. Instituto Histologia y Embriologia de Mendoza "Dr. M. Burgos"; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina
description Mast cells (MC) are predominantly localized at the interface between host and environment such as skin and mucosal surfaces. They are able to perceive a variety of allergens and invading pathogens. In oral tissues, degranulation of mast cells has been a consistent feature of inflammatory lesion like liquen planus, gingivitis, periapical process and tumoral responsive. The aim of the present study is to describe the morphology and to establish the homing time in the tongue?s connective tissue of rats. Tongue sections were collected from Wistar rats processed and included in paraffin wax, cut and stained with toluide blue and alcian blue-safranin and immunoenzyme staining procedure with Monoclonal Antibody to mast cell Tryptase. The total number of mast cells was counted and the area was measured to estimate the population density (mm2) and the individual cell morphology. Results showed morphology changes and a series of variations between the first and the second week samples after birth (p?®0.001), but there were not changes between intrauterus and newborn period. Mast cells weredetected from the fifteenth day of intrauterine life in closed relation with skeletal muscle cells. These data suggest a quick MT adaptation and a strategic location that allow them to react against different oral antigens. More studies are going to be necessary to elucidate this phenomenon.
publishDate 2013
dc.date.none.fl_str_mv 2013-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/9847
Zavala, Walther David; Foscolo, Mabel Rosa; Davila, J.; Cavicchia, Juan Carlos; Early development of mast cell system in lingual tissues of intrauterine and newborn rats; International Journal of Sciences; International Journal of Sciences; 2; 9; 9-2013; 86-89
2410-4477
2305-3925
url http://hdl.handle.net/11336/9847
identifier_str_mv Zavala, Walther David; Foscolo, Mabel Rosa; Davila, J.; Cavicchia, Juan Carlos; Early development of mast cell system in lingual tissues of intrauterine and newborn rats; International Journal of Sciences; International Journal of Sciences; 2; 9; 9-2013; 86-89
2410-4477
2305-3925
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.ijsciences.com/pub/article/264
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv International Journal of Sciences
publisher.none.fl_str_mv International Journal of Sciences
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844613609208938496
score 13.070432

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