A Price to Pay for Adult Neurogenesis
- Autores
- Schinder, Alejandro Fabian; Mongiat, Lucas Alberto
- Año de publicación
- 2014
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- We tend to believe that plasticity is what makes brain circuits adaptable to continuous changes in environmental demands and that greater brain plasticity should result in a better ability to cope with the surrounding world. To adapt to everyday life, animals explore, learn, and remember, and these tasks make use of various cortical structures, including the hippocampus. The dentate gyrus, part of the hippocampus, is a remarkable structure in that it is one of two areas of the adult mammalian brain, including the human brain, that continue to generate new neurons throughout postnatal life (1). It is well established that adult-born neurons integrate into preexisting neuronal networks and participate in information processing (2). Much evidence accumulated over the past decade supports the hypothesis that adult neurogenesis itself is a type of circuit plasticity required for hippocampus-dependent learning and memory recall. The work by Akers et al. on page 598 of this issue (3) now shows that adult hippocampal neurogenesis may also promote forgetting.
Fil: Schinder, Alejandro Fabian. Fundación Instituto Leloir; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina
Fil: Mongiat, Lucas Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Patagonia Norte. Instituto de Investigación En Biodiversidad y Medioambiente; Argentina - Materia
-
Adult Neurogenesis
Hypocampus
Memory
Dentate Gyrus - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/11815
Ver los metadatos del registro completo
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A Price to Pay for Adult NeurogenesisSchinder, Alejandro FabianMongiat, Lucas AlbertoAdult NeurogenesisHypocampusMemoryDentate Gyrushttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1We tend to believe that plasticity is what makes brain circuits adaptable to continuous changes in environmental demands and that greater brain plasticity should result in a better ability to cope with the surrounding world. To adapt to everyday life, animals explore, learn, and remember, and these tasks make use of various cortical structures, including the hippocampus. The dentate gyrus, part of the hippocampus, is a remarkable structure in that it is one of two areas of the adult mammalian brain, including the human brain, that continue to generate new neurons throughout postnatal life (1). It is well established that adult-born neurons integrate into preexisting neuronal networks and participate in information processing (2). Much evidence accumulated over the past decade supports the hypothesis that adult neurogenesis itself is a type of circuit plasticity required for hippocampus-dependent learning and memory recall. The work by Akers et al. on page 598 of this issue (3) now shows that adult hippocampal neurogenesis may also promote forgetting.Fil: Schinder, Alejandro Fabian. Fundación Instituto Leloir; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; ArgentinaFil: Mongiat, Lucas Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Patagonia Norte. Instituto de Investigación En Biodiversidad y Medioambiente; ArgentinaAmerican Association For The Advancement Of Science2014-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/11815Schinder, Alejandro Fabian; Mongiat, Lucas Alberto; A Price to Pay for Adult Neurogenesis; American Association For The Advancement Of Science; Science; 344; 6184; 5-2014; 594-5950036-8075enginfo:eu-repo/semantics/altIdentifier/url/http://science.sciencemag.org/content/344/6184/594info:eu-repo/semantics/altIdentifier/url/http://dx.doi.org/10.1126/science.1254236info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:44:52Zoai:ri.conicet.gov.ar:11336/11815instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:44:52.902CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
A Price to Pay for Adult Neurogenesis |
title |
A Price to Pay for Adult Neurogenesis |
spellingShingle |
A Price to Pay for Adult Neurogenesis Schinder, Alejandro Fabian Adult Neurogenesis Hypocampus Memory Dentate Gyrus |
title_short |
A Price to Pay for Adult Neurogenesis |
title_full |
A Price to Pay for Adult Neurogenesis |
title_fullStr |
A Price to Pay for Adult Neurogenesis |
title_full_unstemmed |
A Price to Pay for Adult Neurogenesis |
title_sort |
A Price to Pay for Adult Neurogenesis |
dc.creator.none.fl_str_mv |
Schinder, Alejandro Fabian Mongiat, Lucas Alberto |
author |
Schinder, Alejandro Fabian |
author_facet |
Schinder, Alejandro Fabian Mongiat, Lucas Alberto |
author_role |
author |
author2 |
Mongiat, Lucas Alberto |
author2_role |
author |
dc.subject.none.fl_str_mv |
Adult Neurogenesis Hypocampus Memory Dentate Gyrus |
topic |
Adult Neurogenesis Hypocampus Memory Dentate Gyrus |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
We tend to believe that plasticity is what makes brain circuits adaptable to continuous changes in environmental demands and that greater brain plasticity should result in a better ability to cope with the surrounding world. To adapt to everyday life, animals explore, learn, and remember, and these tasks make use of various cortical structures, including the hippocampus. The dentate gyrus, part of the hippocampus, is a remarkable structure in that it is one of two areas of the adult mammalian brain, including the human brain, that continue to generate new neurons throughout postnatal life (1). It is well established that adult-born neurons integrate into preexisting neuronal networks and participate in information processing (2). Much evidence accumulated over the past decade supports the hypothesis that adult neurogenesis itself is a type of circuit plasticity required for hippocampus-dependent learning and memory recall. The work by Akers et al. on page 598 of this issue (3) now shows that adult hippocampal neurogenesis may also promote forgetting. Fil: Schinder, Alejandro Fabian. Fundación Instituto Leloir; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina Fil: Mongiat, Lucas Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Patagonia Norte. Instituto de Investigación En Biodiversidad y Medioambiente; Argentina |
description |
We tend to believe that plasticity is what makes brain circuits adaptable to continuous changes in environmental demands and that greater brain plasticity should result in a better ability to cope with the surrounding world. To adapt to everyday life, animals explore, learn, and remember, and these tasks make use of various cortical structures, including the hippocampus. The dentate gyrus, part of the hippocampus, is a remarkable structure in that it is one of two areas of the adult mammalian brain, including the human brain, that continue to generate new neurons throughout postnatal life (1). It is well established that adult-born neurons integrate into preexisting neuronal networks and participate in information processing (2). Much evidence accumulated over the past decade supports the hypothesis that adult neurogenesis itself is a type of circuit plasticity required for hippocampus-dependent learning and memory recall. The work by Akers et al. on page 598 of this issue (3) now shows that adult hippocampal neurogenesis may also promote forgetting. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-05 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/11815 Schinder, Alejandro Fabian; Mongiat, Lucas Alberto; A Price to Pay for Adult Neurogenesis; American Association For The Advancement Of Science; Science; 344; 6184; 5-2014; 594-595 0036-8075 |
url |
http://hdl.handle.net/11336/11815 |
identifier_str_mv |
Schinder, Alejandro Fabian; Mongiat, Lucas Alberto; A Price to Pay for Adult Neurogenesis; American Association For The Advancement Of Science; Science; 344; 6184; 5-2014; 594-595 0036-8075 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/http://science.sciencemag.org/content/344/6184/594 info:eu-repo/semantics/altIdentifier/url/http://dx.doi.org/10.1126/science.1254236 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
American Association For The Advancement Of Science |
publisher.none.fl_str_mv |
American Association For The Advancement Of Science |
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reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) |
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CONICET Digital (CONICET) |
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Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
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dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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13.13397 |