Chemical characterization and biological activities of Tessaria absinthiodes (Hook. & Arn.) dc. (Asteraceae) decoction

Autores
Gómez, J.; Simirgiotis, M. J.; Lima, Beatriz Viviana; Gamarra Luques, Carlos Diego; Bórquez, J.; Caballero, D.; Tapia, A.
Año de publicación
2019
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
The decoction of Tessaria absinthioides is used in traditional medicine of South America as a hypocholesterolemic, balsamic, and expectorant, it is also useful for the prevention of hepatitis, renal insufficiency, diabetes and used as digestive. A lyophilized decoction from the aerial parts of this plant collected in San Juan (TLDSJ) and Mendoza (TLDM) provinces (Argentine) and one collection from Antofagasta, Chile (TLDCH), were evaluated regarding antioxidant activities, phenolics and flavonoids content and UHPLC-MS metabolome fingerprinting which revealed the presence of several small bioactive compounds. The antioxidant properties were evaluated by free radical scavenging methods (DPPH and TEAC), ferric-reducing antioxidant power (FRAP) and lipoperoxidation in erythrocytes (LP). The antibacterial activity was evaluated according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. TLDSJ, TLDSJ and TLDCH displayed a strong DPPH scavenging activity (IC50 = 42, 41.6 and 43 µg/mL respectively) and inhibition of lipoperoxidation in erythrocytes (86-88 % at 250 µgTLD/mL), while a less effect in the FRAP and ABTS antioxidant assays were found. Additionally, the decoctions showed a content of phenolics compounds of 94 mg GAE/g, 185 GAE/g and 64 GAE/g, for TLDSJ, TLDM TLDCH samples respectively. Regarding the flavonoid content, the Chilean sample was highlighted with 19 mg QE/g. In this work thirty phenolics compounds including sesquiterpenes, flavonoids, and phenolics acids were rapidly identified in TLDSJ, TLDM and TLDCH decoctions by means of ultrahigh resolution liquidchromatography orbitrap MS analysis (UHPLC-PDAOT-MS) for the first time, which support that the medicinal decoction from both countries is a valuable natural product with antioxidant effects and with potential to improve human health. Additionally, this research opens a pathway for the development of important phytomedicine products.
Fil: Gómez, J.. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Biotecnología; Argentina
Fil: Simirgiotis, M. J.. Universidad Austral de Chile; Chile
Fil: Lima, Beatriz Viviana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; Argentina. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Biotecnología; Argentina
Fil: Gamarra Luques, Carlos Diego. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina
Fil: Bórquez, J.. Universidad de Antofagasta. Facultad de Ciencias Básicas. Laboratorio de Productos Naturales; Chile
Fil: Caballero, D.. Hospital Público Descentralizado Dr. Marcial Quiroga.; Argentina
Fil: Tapia, A.. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Biotecnología; Argentina
XXXVII Reunión Científica Anual de la Sociedad de Biología de Cuyo
San Luis
Argentina
Sociedad de Biología de Cuyo
Materia
CHEMICAL CHARACTERIZATION
BIOLOGICAL ACTIVITIES
TESSARIA ABSINTHIODES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/161399
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/161399
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Chemical characterization and biological activities of Tessaria absinthiodes (Hook. & Arn.) dc. (Asteraceae) decoctionGómez, J.Simirgiotis, M. J.Lima, Beatriz VivianaGamarra Luques, Carlos DiegoBórquez, J.Caballero, D.Tapia, A.CHEMICAL CHARACTERIZATIONBIOLOGICAL ACTIVITIESTESSARIA ABSINTHIODEShttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1The decoction of Tessaria absinthioides is used in traditional medicine of South America as a hypocholesterolemic, balsamic, and expectorant, it is also useful for the prevention of hepatitis, renal insufficiency, diabetes and used as digestive. A lyophilized decoction from the aerial parts of this plant collected in San Juan (TLDSJ) and Mendoza (TLDM) provinces (Argentine) and one collection from Antofagasta, Chile (TLDCH), were evaluated regarding antioxidant activities, phenolics and flavonoids content and UHPLC-MS metabolome fingerprinting which revealed the presence of several small bioactive compounds. The antioxidant properties were evaluated by free radical scavenging methods (DPPH and TEAC), ferric-reducing antioxidant power (FRAP) and lipoperoxidation in erythrocytes (LP). The antibacterial activity was evaluated according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. TLDSJ, TLDSJ and TLDCH displayed a strong DPPH scavenging activity (IC50 = 42, 41.6 and 43 µg/mL respectively) and inhibition of lipoperoxidation in erythrocytes (86-88 % at 250 µgTLD/mL), while a less effect in the FRAP and ABTS antioxidant assays were found. Additionally, the decoctions showed a content of phenolics compounds of 94 mg GAE/g, 185 GAE/g and 64 GAE/g, for TLDSJ, TLDM TLDCH samples respectively. Regarding the flavonoid content, the Chilean sample was highlighted with 19 mg QE/g. In this work thirty phenolics compounds including sesquiterpenes, flavonoids, and phenolics acids were rapidly identified in TLDSJ, TLDM and TLDCH decoctions by means of ultrahigh resolution liquidchromatography orbitrap MS analysis (UHPLC-PDAOT-MS) for the first time, which support that the medicinal decoction from both countries is a valuable natural product with antioxidant effects and with potential to improve human health. Additionally, this research opens a pathway for the development of important phytomedicine products.Fil: Gómez, J.. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Biotecnología; ArgentinaFil: Simirgiotis, M. J.. Universidad Austral de Chile; ChileFil: Lima, Beatriz Viviana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; Argentina. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Biotecnología; ArgentinaFil: Gamarra Luques, Carlos Diego. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; ArgentinaFil: Bórquez, J.. Universidad de Antofagasta. Facultad de Ciencias Básicas. Laboratorio de Productos Naturales; ChileFil: Caballero, D.. Hospital Público Descentralizado Dr. Marcial Quiroga.; ArgentinaFil: Tapia, A.. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Biotecnología; ArgentinaXXXVII Reunión Científica Anual de la Sociedad de Biología de CuyoSan LuisArgentinaSociedad de Biología de CuyoSociedad de Biología de Cuyo2019info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectReuniónBookhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/161399Chemical characterization and biological activities of Tessaria absinthiodes (Hook. & Arn.) dc. (Asteraceae) decoction; XXXVII Reunión Científica Anual de la Sociedad de Biología de Cuyo; San Luis; Argentina; 2019; 121-122CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://sbcuyo.org.ar/libro-de-resumenes-2019/Nacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:10:34Zoai:ri.conicet.gov.ar:11336/161399instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:10:34.987CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Chemical characterization and biological activities of Tessaria absinthiodes (Hook. & Arn.) dc. (Asteraceae) decoction
title Chemical characterization and biological activities of Tessaria absinthiodes (Hook. & Arn.) dc. (Asteraceae) decoction
spellingShingle Chemical characterization and biological activities of Tessaria absinthiodes (Hook. & Arn.) dc. (Asteraceae) decoction
Gómez, J.
CHEMICAL CHARACTERIZATION
BIOLOGICAL ACTIVITIES
TESSARIA ABSINTHIODES
title_short Chemical characterization and biological activities of Tessaria absinthiodes (Hook. & Arn.) dc. (Asteraceae) decoction
title_full Chemical characterization and biological activities of Tessaria absinthiodes (Hook. & Arn.) dc. (Asteraceae) decoction
title_fullStr Chemical characterization and biological activities of Tessaria absinthiodes (Hook. & Arn.) dc. (Asteraceae) decoction
title_full_unstemmed Chemical characterization and biological activities of Tessaria absinthiodes (Hook. & Arn.) dc. (Asteraceae) decoction
title_sort Chemical characterization and biological activities of Tessaria absinthiodes (Hook. & Arn.) dc. (Asteraceae) decoction
dc.creator.none.fl_str_mv Gómez, J.
Simirgiotis, M. J.
Lima, Beatriz Viviana
Gamarra Luques, Carlos Diego
Bórquez, J.
Caballero, D.
Tapia, A.
author Gómez, J.
author_facet Gómez, J.
Simirgiotis, M. J.
Lima, Beatriz Viviana
Gamarra Luques, Carlos Diego
Bórquez, J.
Caballero, D.
Tapia, A.
author_role author
author2 Simirgiotis, M. J.
Lima, Beatriz Viviana
Gamarra Luques, Carlos Diego
Bórquez, J.
Caballero, D.
Tapia, A.
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv CHEMICAL CHARACTERIZATION
BIOLOGICAL ACTIVITIES
TESSARIA ABSINTHIODES
topic CHEMICAL CHARACTERIZATION
BIOLOGICAL ACTIVITIES
TESSARIA ABSINTHIODES
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The decoction of Tessaria absinthioides is used in traditional medicine of South America as a hypocholesterolemic, balsamic, and expectorant, it is also useful for the prevention of hepatitis, renal insufficiency, diabetes and used as digestive. A lyophilized decoction from the aerial parts of this plant collected in San Juan (TLDSJ) and Mendoza (TLDM) provinces (Argentine) and one collection from Antofagasta, Chile (TLDCH), were evaluated regarding antioxidant activities, phenolics and flavonoids content and UHPLC-MS metabolome fingerprinting which revealed the presence of several small bioactive compounds. The antioxidant properties were evaluated by free radical scavenging methods (DPPH and TEAC), ferric-reducing antioxidant power (FRAP) and lipoperoxidation in erythrocytes (LP). The antibacterial activity was evaluated according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. TLDSJ, TLDSJ and TLDCH displayed a strong DPPH scavenging activity (IC50 = 42, 41.6 and 43 µg/mL respectively) and inhibition of lipoperoxidation in erythrocytes (86-88 % at 250 µgTLD/mL), while a less effect in the FRAP and ABTS antioxidant assays were found. Additionally, the decoctions showed a content of phenolics compounds of 94 mg GAE/g, 185 GAE/g and 64 GAE/g, for TLDSJ, TLDM TLDCH samples respectively. Regarding the flavonoid content, the Chilean sample was highlighted with 19 mg QE/g. In this work thirty phenolics compounds including sesquiterpenes, flavonoids, and phenolics acids were rapidly identified in TLDSJ, TLDM and TLDCH decoctions by means of ultrahigh resolution liquidchromatography orbitrap MS analysis (UHPLC-PDAOT-MS) for the first time, which support that the medicinal decoction from both countries is a valuable natural product with antioxidant effects and with potential to improve human health. Additionally, this research opens a pathway for the development of important phytomedicine products.
Fil: Gómez, J.. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Biotecnología; Argentina
Fil: Simirgiotis, M. J.. Universidad Austral de Chile; Chile
Fil: Lima, Beatriz Viviana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; Argentina. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Biotecnología; Argentina
Fil: Gamarra Luques, Carlos Diego. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina
Fil: Bórquez, J.. Universidad de Antofagasta. Facultad de Ciencias Básicas. Laboratorio de Productos Naturales; Chile
Fil: Caballero, D.. Hospital Público Descentralizado Dr. Marcial Quiroga.; Argentina
Fil: Tapia, A.. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Biotecnología; Argentina
XXXVII Reunión Científica Anual de la Sociedad de Biología de Cuyo
San Luis
Argentina
Sociedad de Biología de Cuyo
description The decoction of Tessaria absinthioides is used in traditional medicine of South America as a hypocholesterolemic, balsamic, and expectorant, it is also useful for the prevention of hepatitis, renal insufficiency, diabetes and used as digestive. A lyophilized decoction from the aerial parts of this plant collected in San Juan (TLDSJ) and Mendoza (TLDM) provinces (Argentine) and one collection from Antofagasta, Chile (TLDCH), were evaluated regarding antioxidant activities, phenolics and flavonoids content and UHPLC-MS metabolome fingerprinting which revealed the presence of several small bioactive compounds. The antioxidant properties were evaluated by free radical scavenging methods (DPPH and TEAC), ferric-reducing antioxidant power (FRAP) and lipoperoxidation in erythrocytes (LP). The antibacterial activity was evaluated according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. TLDSJ, TLDSJ and TLDCH displayed a strong DPPH scavenging activity (IC50 = 42, 41.6 and 43 µg/mL respectively) and inhibition of lipoperoxidation in erythrocytes (86-88 % at 250 µgTLD/mL), while a less effect in the FRAP and ABTS antioxidant assays were found. Additionally, the decoctions showed a content of phenolics compounds of 94 mg GAE/g, 185 GAE/g and 64 GAE/g, for TLDSJ, TLDM TLDCH samples respectively. Regarding the flavonoid content, the Chilean sample was highlighted with 19 mg QE/g. In this work thirty phenolics compounds including sesquiterpenes, flavonoids, and phenolics acids were rapidly identified in TLDSJ, TLDM and TLDCH decoctions by means of ultrahigh resolution liquidchromatography orbitrap MS analysis (UHPLC-PDAOT-MS) for the first time, which support that the medicinal decoction from both countries is a valuable natural product with antioxidant effects and with potential to improve human health. Additionally, this research opens a pathway for the development of important phytomedicine products.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
Reunión
Book
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
status_str publishedVersion
format conferenceObject
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/161399
Chemical characterization and biological activities of Tessaria absinthiodes (Hook. & Arn.) dc. (Asteraceae) decoction; XXXVII Reunión Científica Anual de la Sociedad de Biología de Cuyo; San Luis; Argentina; 2019; 121-122
CONICET Digital
CONICET
url http://hdl.handle.net/11336/161399
identifier_str_mv Chemical characterization and biological activities of Tessaria absinthiodes (Hook. & Arn.) dc. (Asteraceae) decoction; XXXVII Reunión Científica Anual de la Sociedad de Biología de Cuyo; San Luis; Argentina; 2019; 121-122
CONICET Digital
CONICET
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language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://sbcuyo.org.ar/libro-de-resumenes-2019/
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
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application/pdf
application/pdf
dc.coverage.none.fl_str_mv Nacional
dc.publisher.none.fl_str_mv Sociedad de Biología de Cuyo
publisher.none.fl_str_mv Sociedad de Biología de Cuyo
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
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reponame_str CONICET Digital (CONICET)
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repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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