Pregnancy galectinology: Insights into a complex network of glycan binding proteins

Autores
Blois, Sandra M.; Dveksler, Gabriela; Vasta, Gerardo R.; Freitag, Nancy; Blanchard, Véronique; Barrientos, Gabriela Laura
Año de publicación
2019
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Galectins are a phylogenetically conserved family of soluble β-galactoside binding proteins, consisting of 15 different types, each with a specific function. Galectins contribute to placentation by regulating trophoblast development, migration, and invasion during early pregnancy. In addition, galectins are critical players regulating maternal immune tolerance to the embedded embryo. Recently, the role of galectins in angiogenesis during decidualization and in placenta formation has gained attention. Altered expression of galectins is associated with abnormal pregnancies and infertility. This review focuses on the role of galectins in pregnancy-associated processes and discusses the relevance of galectin-glycan interactions as potential therapeutic targets in pregnancy disorders.
Fil: Blois, Sandra M.. Universität zu Berlin; Alemania
Fil: Dveksler, Gabriela. No especifíca;
Fil: Vasta, Gerardo R.. University of Maryland; Estados Unidos
Fil: Freitag, Nancy. Universität zu Berlin; Alemania
Fil: Blanchard, Véronique. Universität zu Berlin; Alemania
Fil: Barrientos, Gabriela Laura. Universidad de Buenos Aires; Argentina. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
GALECTINS
GLYCANS
PLACENTATION
PREECLAMPSIA
PREGNANCY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/128615
Acceder
id CONICETDig_5b93d150c67de36addceb678cf4f49b4
oai_identifier_str oai:ri.conicet.gov.ar:11336/128615
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Pregnancy galectinology: Insights into a complex network of glycan binding proteinsBlois, Sandra M.Dveksler, GabrielaVasta, Gerardo R.Freitag, NancyBlanchard, VéroniqueBarrientos, Gabriela LauraGALECTINSGLYCANSPLACENTATIONPREECLAMPSIAPREGNANCYhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Galectins are a phylogenetically conserved family of soluble β-galactoside binding proteins, consisting of 15 different types, each with a specific function. Galectins contribute to placentation by regulating trophoblast development, migration, and invasion during early pregnancy. In addition, galectins are critical players regulating maternal immune tolerance to the embedded embryo. Recently, the role of galectins in angiogenesis during decidualization and in placenta formation has gained attention. Altered expression of galectins is associated with abnormal pregnancies and infertility. This review focuses on the role of galectins in pregnancy-associated processes and discusses the relevance of galectin-glycan interactions as potential therapeutic targets in pregnancy disorders.Fil: Blois, Sandra M.. Universität zu Berlin; AlemaniaFil: Dveksler, Gabriela. No especifíca;Fil: Vasta, Gerardo R.. University of Maryland; Estados UnidosFil: Freitag, Nancy. Universität zu Berlin; AlemaniaFil: Blanchard, Véronique. Universität zu Berlin; AlemaniaFil: Barrientos, Gabriela Laura. Universidad de Buenos Aires; Argentina. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFrontiers Media S.A.2019-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/128615Blois, Sandra M.; Dveksler, Gabriela; Vasta, Gerardo R.; Freitag, Nancy; Blanchard, Véronique; et al.; Pregnancy galectinology: Insights into a complex network of glycan binding proteins; Frontiers Media S.A.; Frontiers in Immunology; 10; MAY; 5-2019; 1-151664-3224CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3389/fimmu.2019.01166info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fimmu.2019.01166/fullinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:55:31Zoai:ri.conicet.gov.ar:11336/128615instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:55:31.721CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Pregnancy galectinology: Insights into a complex network of glycan binding proteins
title Pregnancy galectinology: Insights into a complex network of glycan binding proteins
spellingShingle Pregnancy galectinology: Insights into a complex network of glycan binding proteins
Blois, Sandra M.
GALECTINS
GLYCANS
PLACENTATION
PREECLAMPSIA
PREGNANCY
title_short Pregnancy galectinology: Insights into a complex network of glycan binding proteins
title_full Pregnancy galectinology: Insights into a complex network of glycan binding proteins
title_fullStr Pregnancy galectinology: Insights into a complex network of glycan binding proteins
title_full_unstemmed Pregnancy galectinology: Insights into a complex network of glycan binding proteins
title_sort Pregnancy galectinology: Insights into a complex network of glycan binding proteins
dc.creator.none.fl_str_mv Blois, Sandra M.
Dveksler, Gabriela
Vasta, Gerardo R.
Freitag, Nancy
Blanchard, Véronique
Barrientos, Gabriela Laura
author Blois, Sandra M.
author_facet Blois, Sandra M.
Dveksler, Gabriela
Vasta, Gerardo R.
Freitag, Nancy
Blanchard, Véronique
Barrientos, Gabriela Laura
author_role author
author2 Dveksler, Gabriela
Vasta, Gerardo R.
Freitag, Nancy
Blanchard, Véronique
Barrientos, Gabriela Laura
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv GALECTINS
GLYCANS
PLACENTATION
PREECLAMPSIA
PREGNANCY
topic GALECTINS
GLYCANS
PLACENTATION
PREECLAMPSIA
PREGNANCY
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Galectins are a phylogenetically conserved family of soluble β-galactoside binding proteins, consisting of 15 different types, each with a specific function. Galectins contribute to placentation by regulating trophoblast development, migration, and invasion during early pregnancy. In addition, galectins are critical players regulating maternal immune tolerance to the embedded embryo. Recently, the role of galectins in angiogenesis during decidualization and in placenta formation has gained attention. Altered expression of galectins is associated with abnormal pregnancies and infertility. This review focuses on the role of galectins in pregnancy-associated processes and discusses the relevance of galectin-glycan interactions as potential therapeutic targets in pregnancy disorders.
Fil: Blois, Sandra M.. Universität zu Berlin; Alemania
Fil: Dveksler, Gabriela. No especifíca;
Fil: Vasta, Gerardo R.. University of Maryland; Estados Unidos
Fil: Freitag, Nancy. Universität zu Berlin; Alemania
Fil: Blanchard, Véronique. Universität zu Berlin; Alemania
Fil: Barrientos, Gabriela Laura. Universidad de Buenos Aires; Argentina. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Galectins are a phylogenetically conserved family of soluble β-galactoside binding proteins, consisting of 15 different types, each with a specific function. Galectins contribute to placentation by regulating trophoblast development, migration, and invasion during early pregnancy. In addition, galectins are critical players regulating maternal immune tolerance to the embedded embryo. Recently, the role of galectins in angiogenesis during decidualization and in placenta formation has gained attention. Altered expression of galectins is associated with abnormal pregnancies and infertility. This review focuses on the role of galectins in pregnancy-associated processes and discusses the relevance of galectin-glycan interactions as potential therapeutic targets in pregnancy disorders.
publishDate 2019
dc.date.none.fl_str_mv 2019-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/128615
Blois, Sandra M.; Dveksler, Gabriela; Vasta, Gerardo R.; Freitag, Nancy; Blanchard, Véronique; et al.; Pregnancy galectinology: Insights into a complex network of glycan binding proteins; Frontiers Media S.A.; Frontiers in Immunology; 10; MAY; 5-2019; 1-15
1664-3224
CONICET Digital
CONICET
url http://hdl.handle.net/11336/128615
identifier_str_mv Blois, Sandra M.; Dveksler, Gabriela; Vasta, Gerardo R.; Freitag, Nancy; Blanchard, Véronique; et al.; Pregnancy galectinology: Insights into a complex network of glycan binding proteins; Frontiers Media S.A.; Frontiers in Immunology; 10; MAY; 5-2019; 1-15
1664-3224
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.3389/fimmu.2019.01166
info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fimmu.2019.01166/full
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Frontiers Media S.A.
publisher.none.fl_str_mv Frontiers Media S.A.
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269349876858880
score 13.13397

Publicaciones similares