Protein-glycan interactions in the control of innate and adaptive immune responses

Autores
Kooyk, Yvette Van; Rabinovich, Gabriel Adrián
Año de publicación
2008
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The importance of protein glycosylation in the migration of immune cells throughout the body has been extensively appreciated. However, our awareness of the impact of glycosylation on the regulation of innate and adaptive immune responses is relatively new. An increasing number of studies reveal the relevance of glycosylation to pathogen recognition, to the modulation of the innate immune system and to the control of immune cell homeostasis and inflammation. Similarly important is the effect of glycan-containing 'information' in the development of autoimmune diseases and cancer. In this review, we provide an overview of these new directions and their impact in the field of glycoimmunology.
Fil: Kooyk, Yvette Van. University of Amsterdam; Países Bajos
Fil: Rabinovich, Gabriel Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Materia
Glycoimmunology
Glycans
Lectins
Galectins
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/25867

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network_name_str CONICET Digital (CONICET)
spelling Protein-glycan interactions in the control of innate and adaptive immune responsesKooyk, Yvette VanRabinovich, Gabriel AdriánGlycoimmunologyGlycansLectinsGalectinshttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3The importance of protein glycosylation in the migration of immune cells throughout the body has been extensively appreciated. However, our awareness of the impact of glycosylation on the regulation of innate and adaptive immune responses is relatively new. An increasing number of studies reveal the relevance of glycosylation to pathogen recognition, to the modulation of the innate immune system and to the control of immune cell homeostasis and inflammation. Similarly important is the effect of glycan-containing 'information' in the development of autoimmune diseases and cancer. In this review, we provide an overview of these new directions and their impact in the field of glycoimmunology.Fil: Kooyk, Yvette Van. University of Amsterdam; Países BajosFil: Rabinovich, Gabriel Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaNature Publishing Group2008-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/25867Kooyk, Yvette Van; Rabinovich, Gabriel Adrián; Protein-glycan interactions in the control of innate and adaptive immune responses; Nature Publishing Group; Nature Immunology (print); 9; 6; 6-2008; 1-91529-29081529-2916CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.nature.com/doifinder/10.1038/ni.f.203info:eu-repo/semantics/altIdentifier/doi/10.1038/ni.f.203info:eu-repo/semantics/altIdentifier/pmid/18490910info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:03:00Zoai:ri.conicet.gov.ar:11336/25867instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:03:00.607CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Protein-glycan interactions in the control of innate and adaptive immune responses
title Protein-glycan interactions in the control of innate and adaptive immune responses
spellingShingle Protein-glycan interactions in the control of innate and adaptive immune responses
Kooyk, Yvette Van
Glycoimmunology
Glycans
Lectins
Galectins
title_short Protein-glycan interactions in the control of innate and adaptive immune responses
title_full Protein-glycan interactions in the control of innate and adaptive immune responses
title_fullStr Protein-glycan interactions in the control of innate and adaptive immune responses
title_full_unstemmed Protein-glycan interactions in the control of innate and adaptive immune responses
title_sort Protein-glycan interactions in the control of innate and adaptive immune responses
dc.creator.none.fl_str_mv Kooyk, Yvette Van
Rabinovich, Gabriel Adrián
author Kooyk, Yvette Van
author_facet Kooyk, Yvette Van
Rabinovich, Gabriel Adrián
author_role author
author2 Rabinovich, Gabriel Adrián
author2_role author
dc.subject.none.fl_str_mv Glycoimmunology
Glycans
Lectins
Galectins
topic Glycoimmunology
Glycans
Lectins
Galectins
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The importance of protein glycosylation in the migration of immune cells throughout the body has been extensively appreciated. However, our awareness of the impact of glycosylation on the regulation of innate and adaptive immune responses is relatively new. An increasing number of studies reveal the relevance of glycosylation to pathogen recognition, to the modulation of the innate immune system and to the control of immune cell homeostasis and inflammation. Similarly important is the effect of glycan-containing 'information' in the development of autoimmune diseases and cancer. In this review, we provide an overview of these new directions and their impact in the field of glycoimmunology.
Fil: Kooyk, Yvette Van. University of Amsterdam; Países Bajos
Fil: Rabinovich, Gabriel Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
description The importance of protein glycosylation in the migration of immune cells throughout the body has been extensively appreciated. However, our awareness of the impact of glycosylation on the regulation of innate and adaptive immune responses is relatively new. An increasing number of studies reveal the relevance of glycosylation to pathogen recognition, to the modulation of the innate immune system and to the control of immune cell homeostasis and inflammation. Similarly important is the effect of glycan-containing 'information' in the development of autoimmune diseases and cancer. In this review, we provide an overview of these new directions and their impact in the field of glycoimmunology.
publishDate 2008
dc.date.none.fl_str_mv 2008-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/25867
Kooyk, Yvette Van; Rabinovich, Gabriel Adrián; Protein-glycan interactions in the control of innate and adaptive immune responses; Nature Publishing Group; Nature Immunology (print); 9; 6; 6-2008; 1-9
1529-2908
1529-2916
CONICET Digital
CONICET
url http://hdl.handle.net/11336/25867
identifier_str_mv Kooyk, Yvette Van; Rabinovich, Gabriel Adrián; Protein-glycan interactions in the control of innate and adaptive immune responses; Nature Publishing Group; Nature Immunology (print); 9; 6; 6-2008; 1-9
1529-2908
1529-2916
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.nature.com/doifinder/10.1038/ni.f.203
info:eu-repo/semantics/altIdentifier/doi/10.1038/ni.f.203
info:eu-repo/semantics/altIdentifier/pmid/18490910
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Nature Publishing Group
publisher.none.fl_str_mv Nature Publishing Group
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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