Protein-glycan interactions in the control of innate and adaptive immune responses
- Autores
- Kooyk, Yvette Van; Rabinovich, Gabriel Adrián
- Año de publicación
- 2008
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- The importance of protein glycosylation in the migration of immune cells throughout the body has been extensively appreciated. However, our awareness of the impact of glycosylation on the regulation of innate and adaptive immune responses is relatively new. An increasing number of studies reveal the relevance of glycosylation to pathogen recognition, to the modulation of the innate immune system and to the control of immune cell homeostasis and inflammation. Similarly important is the effect of glycan-containing 'information' in the development of autoimmune diseases and cancer. In this review, we provide an overview of these new directions and their impact in the field of glycoimmunology.
Fil: Kooyk, Yvette Van. University of Amsterdam; Países Bajos
Fil: Rabinovich, Gabriel Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina - Materia
-
Glycoimmunology
Glycans
Lectins
Galectins - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/25867
Ver los metadatos del registro completo
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Protein-glycan interactions in the control of innate and adaptive immune responsesKooyk, Yvette VanRabinovich, Gabriel AdriánGlycoimmunologyGlycansLectinsGalectinshttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3The importance of protein glycosylation in the migration of immune cells throughout the body has been extensively appreciated. However, our awareness of the impact of glycosylation on the regulation of innate and adaptive immune responses is relatively new. An increasing number of studies reveal the relevance of glycosylation to pathogen recognition, to the modulation of the innate immune system and to the control of immune cell homeostasis and inflammation. Similarly important is the effect of glycan-containing 'information' in the development of autoimmune diseases and cancer. In this review, we provide an overview of these new directions and their impact in the field of glycoimmunology.Fil: Kooyk, Yvette Van. University of Amsterdam; Países BajosFil: Rabinovich, Gabriel Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaNature Publishing Group2008-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/25867Kooyk, Yvette Van; Rabinovich, Gabriel Adrián; Protein-glycan interactions in the control of innate and adaptive immune responses; Nature Publishing Group; Nature Immunology (print); 9; 6; 6-2008; 1-91529-29081529-2916CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.nature.com/doifinder/10.1038/ni.f.203info:eu-repo/semantics/altIdentifier/doi/10.1038/ni.f.203info:eu-repo/semantics/altIdentifier/pmid/18490910info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:03:00Zoai:ri.conicet.gov.ar:11336/25867instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:03:00.607CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Protein-glycan interactions in the control of innate and adaptive immune responses |
title |
Protein-glycan interactions in the control of innate and adaptive immune responses |
spellingShingle |
Protein-glycan interactions in the control of innate and adaptive immune responses Kooyk, Yvette Van Glycoimmunology Glycans Lectins Galectins |
title_short |
Protein-glycan interactions in the control of innate and adaptive immune responses |
title_full |
Protein-glycan interactions in the control of innate and adaptive immune responses |
title_fullStr |
Protein-glycan interactions in the control of innate and adaptive immune responses |
title_full_unstemmed |
Protein-glycan interactions in the control of innate and adaptive immune responses |
title_sort |
Protein-glycan interactions in the control of innate and adaptive immune responses |
dc.creator.none.fl_str_mv |
Kooyk, Yvette Van Rabinovich, Gabriel Adrián |
author |
Kooyk, Yvette Van |
author_facet |
Kooyk, Yvette Van Rabinovich, Gabriel Adrián |
author_role |
author |
author2 |
Rabinovich, Gabriel Adrián |
author2_role |
author |
dc.subject.none.fl_str_mv |
Glycoimmunology Glycans Lectins Galectins |
topic |
Glycoimmunology Glycans Lectins Galectins |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.1 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
The importance of protein glycosylation in the migration of immune cells throughout the body has been extensively appreciated. However, our awareness of the impact of glycosylation on the regulation of innate and adaptive immune responses is relatively new. An increasing number of studies reveal the relevance of glycosylation to pathogen recognition, to the modulation of the innate immune system and to the control of immune cell homeostasis and inflammation. Similarly important is the effect of glycan-containing 'information' in the development of autoimmune diseases and cancer. In this review, we provide an overview of these new directions and their impact in the field of glycoimmunology. Fil: Kooyk, Yvette Van. University of Amsterdam; Países Bajos Fil: Rabinovich, Gabriel Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina |
description |
The importance of protein glycosylation in the migration of immune cells throughout the body has been extensively appreciated. However, our awareness of the impact of glycosylation on the regulation of innate and adaptive immune responses is relatively new. An increasing number of studies reveal the relevance of glycosylation to pathogen recognition, to the modulation of the innate immune system and to the control of immune cell homeostasis and inflammation. Similarly important is the effect of glycan-containing 'information' in the development of autoimmune diseases and cancer. In this review, we provide an overview of these new directions and their impact in the field of glycoimmunology. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-06 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/25867 Kooyk, Yvette Van; Rabinovich, Gabriel Adrián; Protein-glycan interactions in the control of innate and adaptive immune responses; Nature Publishing Group; Nature Immunology (print); 9; 6; 6-2008; 1-9 1529-2908 1529-2916 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/25867 |
identifier_str_mv |
Kooyk, Yvette Van; Rabinovich, Gabriel Adrián; Protein-glycan interactions in the control of innate and adaptive immune responses; Nature Publishing Group; Nature Immunology (print); 9; 6; 6-2008; 1-9 1529-2908 1529-2916 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/http://www.nature.com/doifinder/10.1038/ni.f.203 info:eu-repo/semantics/altIdentifier/doi/10.1038/ni.f.203 info:eu-repo/semantics/altIdentifier/pmid/18490910 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Nature Publishing Group |
publisher.none.fl_str_mv |
Nature Publishing Group |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1842269778662653952 |
score |
13.13397 |