Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials

Autores
Frizzo, Laureano Sebastian; Zbrun, María Virginia; Soto, Lorena Paola; Signorini Porchietto, Marcelo Lisandro
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Growth of calves during their first few weeks of life is one of the most important factors affecting their performance during subsequent rearing, and it can be modified by disease, especially gastrointestinal infections. Use of lactic acid bacteria (LAB) is a tool which may maintain the intestinal microbial balance, prevent diarrhea and improve growth. However, a consensus has not been reached as to whether probiotics are effective in improving growth of calves. The objective of this meta-analysis was to assess effects of probiotics on the growth of calves (i.e., body weight gain (BWG), feed efficiency). PubMed and Scopus databases were searched from 1980 to 2010, unrestricted by language. The inclusion criteria were: randomized and controlled experiments using calves less than 5 d of age without apparent disease and with passive immunity, and published in peer reviewed journals. Twenty-one and 14 studies were included to assess probiotic effects on BWG and feed efficiency, respectively. LAB supplementation increased BWG (standardized mean differences (SMD) = 0.22822, 95% confidence interval (CI) 0.1006?0.4638) and improve feed efficiency (SMD = −0.8141, 95% CI −1.2222 to −0.4059), considering the source of heterogeneity and publication biases. Growth of calves was not affected when the LAB was added to whole milk, but beneficial effects occurred when LAB was added to milk replacer. The probiotic effect was not related to the number of LAB strains in the inoculum. The number of calves in the experiments had an impact on the results and conclusions. Probiotics may be an alternative to the antibiotics commonly used as growth promoters in calves.
Fil: Frizzo, Laureano Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina
Fil: Zbrun, María Virginia. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina
Fil: Soto, Lorena Paola. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina
Fil: Signorini Porchietto, Marcelo Lisandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina
Materia
Probiotic
Lactic Acid Bacteria
Calves
Meta-analysis
Growth performance
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/96475
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/96475
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trialsFrizzo, Laureano SebastianZbrun, María VirginiaSoto, Lorena PaolaSignorini Porchietto, Marcelo LisandroProbioticLactic Acid BacteriaCalvesMeta-analysisGrowth performancehttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Growth of calves during their first few weeks of life is one of the most important factors affecting their performance during subsequent rearing, and it can be modified by disease, especially gastrointestinal infections. Use of lactic acid bacteria (LAB) is a tool which may maintain the intestinal microbial balance, prevent diarrhea and improve growth. However, a consensus has not been reached as to whether probiotics are effective in improving growth of calves. The objective of this meta-analysis was to assess effects of probiotics on the growth of calves (i.e., body weight gain (BWG), feed efficiency). PubMed and Scopus databases were searched from 1980 to 2010, unrestricted by language. The inclusion criteria were: randomized and controlled experiments using calves less than 5 d of age without apparent disease and with passive immunity, and published in peer reviewed journals. Twenty-one and 14 studies were included to assess probiotic effects on BWG and feed efficiency, respectively. LAB supplementation increased BWG (standardized mean differences (SMD) = 0.22822, 95% confidence interval (CI) 0.1006?0.4638) and improve feed efficiency (SMD = −0.8141, 95% CI −1.2222 to −0.4059), considering the source of heterogeneity and publication biases. Growth of calves was not affected when the LAB was added to whole milk, but beneficial effects occurred when LAB was added to milk replacer. The probiotic effect was not related to the number of LAB strains in the inoculum. The number of calves in the experiments had an impact on the results and conclusions. Probiotics may be an alternative to the antibiotics commonly used as growth promoters in calves.Fil: Frizzo, Laureano Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; ArgentinaFil: Zbrun, María Virginia. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; ArgentinaFil: Soto, Lorena Paola. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; ArgentinaFil: Signorini Porchietto, Marcelo Lisandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; ArgentinaElsevier Science2011-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/96475Frizzo, Laureano Sebastian; Zbrun, María Virginia; Soto, Lorena Paola; Signorini Porchietto, Marcelo Lisandro; Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials; Elsevier Science; Animal Feed Science and Technology; 169; 3-4; 11-2011; 147-1560377-8401CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/journal/03778401info:eu-repo/semantics/altIdentifier/doi/10.1016/j.anifeedsci.2011.06.009info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:35:18Zoai:ri.conicet.gov.ar:11336/96475instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:35:19.013CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials
title Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials
spellingShingle Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials
Frizzo, Laureano Sebastian
Probiotic
Lactic Acid Bacteria
Calves
Meta-analysis
Growth performance
title_short Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials
title_full Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials
title_fullStr Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials
title_full_unstemmed Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials
title_sort Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials
dc.creator.none.fl_str_mv Frizzo, Laureano Sebastian
Zbrun, María Virginia
Soto, Lorena Paola
Signorini Porchietto, Marcelo Lisandro
author Frizzo, Laureano Sebastian
author_facet Frizzo, Laureano Sebastian
Zbrun, María Virginia
Soto, Lorena Paola
Signorini Porchietto, Marcelo Lisandro
author_role author
author2 Zbrun, María Virginia
Soto, Lorena Paola
Signorini Porchietto, Marcelo Lisandro
author2_role author
author
author
dc.subject.none.fl_str_mv Probiotic
Lactic Acid Bacteria
Calves
Meta-analysis
Growth performance
topic Probiotic
Lactic Acid Bacteria
Calves
Meta-analysis
Growth performance
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv Growth of calves during their first few weeks of life is one of the most important factors affecting their performance during subsequent rearing, and it can be modified by disease, especially gastrointestinal infections. Use of lactic acid bacteria (LAB) is a tool which may maintain the intestinal microbial balance, prevent diarrhea and improve growth. However, a consensus has not been reached as to whether probiotics are effective in improving growth of calves. The objective of this meta-analysis was to assess effects of probiotics on the growth of calves (i.e., body weight gain (BWG), feed efficiency). PubMed and Scopus databases were searched from 1980 to 2010, unrestricted by language. The inclusion criteria were: randomized and controlled experiments using calves less than 5 d of age without apparent disease and with passive immunity, and published in peer reviewed journals. Twenty-one and 14 studies were included to assess probiotic effects on BWG and feed efficiency, respectively. LAB supplementation increased BWG (standardized mean differences (SMD) = 0.22822, 95% confidence interval (CI) 0.1006?0.4638) and improve feed efficiency (SMD = −0.8141, 95% CI −1.2222 to −0.4059), considering the source of heterogeneity and publication biases. Growth of calves was not affected when the LAB was added to whole milk, but beneficial effects occurred when LAB was added to milk replacer. The probiotic effect was not related to the number of LAB strains in the inoculum. The number of calves in the experiments had an impact on the results and conclusions. Probiotics may be an alternative to the antibiotics commonly used as growth promoters in calves.
Fil: Frizzo, Laureano Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina
Fil: Zbrun, María Virginia. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina
Fil: Soto, Lorena Paola. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina
Fil: Signorini Porchietto, Marcelo Lisandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina
description Growth of calves during their first few weeks of life is one of the most important factors affecting their performance during subsequent rearing, and it can be modified by disease, especially gastrointestinal infections. Use of lactic acid bacteria (LAB) is a tool which may maintain the intestinal microbial balance, prevent diarrhea and improve growth. However, a consensus has not been reached as to whether probiotics are effective in improving growth of calves. The objective of this meta-analysis was to assess effects of probiotics on the growth of calves (i.e., body weight gain (BWG), feed efficiency). PubMed and Scopus databases were searched from 1980 to 2010, unrestricted by language. The inclusion criteria were: randomized and controlled experiments using calves less than 5 d of age without apparent disease and with passive immunity, and published in peer reviewed journals. Twenty-one and 14 studies were included to assess probiotic effects on BWG and feed efficiency, respectively. LAB supplementation increased BWG (standardized mean differences (SMD) = 0.22822, 95% confidence interval (CI) 0.1006?0.4638) and improve feed efficiency (SMD = −0.8141, 95% CI −1.2222 to −0.4059), considering the source of heterogeneity and publication biases. Growth of calves was not affected when the LAB was added to whole milk, but beneficial effects occurred when LAB was added to milk replacer. The probiotic effect was not related to the number of LAB strains in the inoculum. The number of calves in the experiments had an impact on the results and conclusions. Probiotics may be an alternative to the antibiotics commonly used as growth promoters in calves.
publishDate 2011
dc.date.none.fl_str_mv 2011-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/96475
Frizzo, Laureano Sebastian; Zbrun, María Virginia; Soto, Lorena Paola; Signorini Porchietto, Marcelo Lisandro; Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials; Elsevier Science; Animal Feed Science and Technology; 169; 3-4; 11-2011; 147-156
0377-8401
CONICET Digital
CONICET
url http://hdl.handle.net/11336/96475
identifier_str_mv Frizzo, Laureano Sebastian; Zbrun, María Virginia; Soto, Lorena Paola; Signorini Porchietto, Marcelo Lisandro; Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials; Elsevier Science; Animal Feed Science and Technology; 169; 3-4; 11-2011; 147-156
0377-8401
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/journal/03778401
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.anifeedsci.2011.06.009
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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