Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials
- Autores
- Frizzo, Laureano Sebastian; Zbrun, María Virginia; Soto, Lorena Paola; Signorini Porchietto, Marcelo Lisandro
- Año de publicación
- 2011
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Growth of calves during their first few weeks of life is one of the most important factors affecting their performance during subsequent rearing, and it can be modified by disease, especially gastrointestinal infections. Use of lactic acid bacteria (LAB) is a tool which may maintain the intestinal microbial balance, prevent diarrhea and improve growth. However, a consensus has not been reached as to whether probiotics are effective in improving growth of calves. The objective of this meta-analysis was to assess effects of probiotics on the growth of calves (i.e., body weight gain (BWG), feed efficiency). PubMed and Scopus databases were searched from 1980 to 2010, unrestricted by language. The inclusion criteria were: randomized and controlled experiments using calves less than 5 d of age without apparent disease and with passive immunity, and published in peer reviewed journals. Twenty-one and 14 studies were included to assess probiotic effects on BWG and feed efficiency, respectively. LAB supplementation increased BWG (standardized mean differences (SMD) = 0.22822, 95% confidence interval (CI) 0.1006?0.4638) and improve feed efficiency (SMD = −0.8141, 95% CI −1.2222 to −0.4059), considering the source of heterogeneity and publication biases. Growth of calves was not affected when the LAB was added to whole milk, but beneficial effects occurred when LAB was added to milk replacer. The probiotic effect was not related to the number of LAB strains in the inoculum. The number of calves in the experiments had an impact on the results and conclusions. Probiotics may be an alternative to the antibiotics commonly used as growth promoters in calves.
Fil: Frizzo, Laureano Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina
Fil: Zbrun, María Virginia. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina
Fil: Soto, Lorena Paola. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina
Fil: Signorini Porchietto, Marcelo Lisandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina - Materia
-
Probiotic
Lactic Acid Bacteria
Calves
Meta-analysis
Growth performance - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/96475
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Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trialsFrizzo, Laureano SebastianZbrun, María VirginiaSoto, Lorena PaolaSignorini Porchietto, Marcelo LisandroProbioticLactic Acid BacteriaCalvesMeta-analysisGrowth performancehttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Growth of calves during their first few weeks of life is one of the most important factors affecting their performance during subsequent rearing, and it can be modified by disease, especially gastrointestinal infections. Use of lactic acid bacteria (LAB) is a tool which may maintain the intestinal microbial balance, prevent diarrhea and improve growth. However, a consensus has not been reached as to whether probiotics are effective in improving growth of calves. The objective of this meta-analysis was to assess effects of probiotics on the growth of calves (i.e., body weight gain (BWG), feed efficiency). PubMed and Scopus databases were searched from 1980 to 2010, unrestricted by language. The inclusion criteria were: randomized and controlled experiments using calves less than 5 d of age without apparent disease and with passive immunity, and published in peer reviewed journals. Twenty-one and 14 studies were included to assess probiotic effects on BWG and feed efficiency, respectively. LAB supplementation increased BWG (standardized mean differences (SMD) = 0.22822, 95% confidence interval (CI) 0.1006?0.4638) and improve feed efficiency (SMD = −0.8141, 95% CI −1.2222 to −0.4059), considering the source of heterogeneity and publication biases. Growth of calves was not affected when the LAB was added to whole milk, but beneficial effects occurred when LAB was added to milk replacer. The probiotic effect was not related to the number of LAB strains in the inoculum. The number of calves in the experiments had an impact on the results and conclusions. Probiotics may be an alternative to the antibiotics commonly used as growth promoters in calves.Fil: Frizzo, Laureano Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; ArgentinaFil: Zbrun, María Virginia. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; ArgentinaFil: Soto, Lorena Paola. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; ArgentinaFil: Signorini Porchietto, Marcelo Lisandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; ArgentinaElsevier Science2011-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/96475Frizzo, Laureano Sebastian; Zbrun, María Virginia; Soto, Lorena Paola; Signorini Porchietto, Marcelo Lisandro; Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials; Elsevier Science; Animal Feed Science and Technology; 169; 3-4; 11-2011; 147-1560377-8401CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/journal/03778401info:eu-repo/semantics/altIdentifier/doi/10.1016/j.anifeedsci.2011.06.009info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:07:58Zoai:ri.conicet.gov.ar:11336/96475instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:07:58.362CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials |
title |
Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials |
spellingShingle |
Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials Frizzo, Laureano Sebastian Probiotic Lactic Acid Bacteria Calves Meta-analysis Growth performance |
title_short |
Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials |
title_full |
Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials |
title_fullStr |
Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials |
title_full_unstemmed |
Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials |
title_sort |
Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials |
dc.creator.none.fl_str_mv |
Frizzo, Laureano Sebastian Zbrun, María Virginia Soto, Lorena Paola Signorini Porchietto, Marcelo Lisandro |
author |
Frizzo, Laureano Sebastian |
author_facet |
Frizzo, Laureano Sebastian Zbrun, María Virginia Soto, Lorena Paola Signorini Porchietto, Marcelo Lisandro |
author_role |
author |
author2 |
Zbrun, María Virginia Soto, Lorena Paola Signorini Porchietto, Marcelo Lisandro |
author2_role |
author author author |
dc.subject.none.fl_str_mv |
Probiotic Lactic Acid Bacteria Calves Meta-analysis Growth performance |
topic |
Probiotic Lactic Acid Bacteria Calves Meta-analysis Growth performance |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/4.3 https://purl.org/becyt/ford/4 |
dc.description.none.fl_txt_mv |
Growth of calves during their first few weeks of life is one of the most important factors affecting their performance during subsequent rearing, and it can be modified by disease, especially gastrointestinal infections. Use of lactic acid bacteria (LAB) is a tool which may maintain the intestinal microbial balance, prevent diarrhea and improve growth. However, a consensus has not been reached as to whether probiotics are effective in improving growth of calves. The objective of this meta-analysis was to assess effects of probiotics on the growth of calves (i.e., body weight gain (BWG), feed efficiency). PubMed and Scopus databases were searched from 1980 to 2010, unrestricted by language. The inclusion criteria were: randomized and controlled experiments using calves less than 5 d of age without apparent disease and with passive immunity, and published in peer reviewed journals. Twenty-one and 14 studies were included to assess probiotic effects on BWG and feed efficiency, respectively. LAB supplementation increased BWG (standardized mean differences (SMD) = 0.22822, 95% confidence interval (CI) 0.1006?0.4638) and improve feed efficiency (SMD = −0.8141, 95% CI −1.2222 to −0.4059), considering the source of heterogeneity and publication biases. Growth of calves was not affected when the LAB was added to whole milk, but beneficial effects occurred when LAB was added to milk replacer. The probiotic effect was not related to the number of LAB strains in the inoculum. The number of calves in the experiments had an impact on the results and conclusions. Probiotics may be an alternative to the antibiotics commonly used as growth promoters in calves. Fil: Frizzo, Laureano Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina Fil: Zbrun, María Virginia. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina Fil: Soto, Lorena Paola. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina Fil: Signorini Porchietto, Marcelo Lisandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública Veterinaria; Argentina |
description |
Growth of calves during their first few weeks of life is one of the most important factors affecting their performance during subsequent rearing, and it can be modified by disease, especially gastrointestinal infections. Use of lactic acid bacteria (LAB) is a tool which may maintain the intestinal microbial balance, prevent diarrhea and improve growth. However, a consensus has not been reached as to whether probiotics are effective in improving growth of calves. The objective of this meta-analysis was to assess effects of probiotics on the growth of calves (i.e., body weight gain (BWG), feed efficiency). PubMed and Scopus databases were searched from 1980 to 2010, unrestricted by language. The inclusion criteria were: randomized and controlled experiments using calves less than 5 d of age without apparent disease and with passive immunity, and published in peer reviewed journals. Twenty-one and 14 studies were included to assess probiotic effects on BWG and feed efficiency, respectively. LAB supplementation increased BWG (standardized mean differences (SMD) = 0.22822, 95% confidence interval (CI) 0.1006?0.4638) and improve feed efficiency (SMD = −0.8141, 95% CI −1.2222 to −0.4059), considering the source of heterogeneity and publication biases. Growth of calves was not affected when the LAB was added to whole milk, but beneficial effects occurred when LAB was added to milk replacer. The probiotic effect was not related to the number of LAB strains in the inoculum. The number of calves in the experiments had an impact on the results and conclusions. Probiotics may be an alternative to the antibiotics commonly used as growth promoters in calves. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-11 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/96475 Frizzo, Laureano Sebastian; Zbrun, María Virginia; Soto, Lorena Paola; Signorini Porchietto, Marcelo Lisandro; Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials; Elsevier Science; Animal Feed Science and Technology; 169; 3-4; 11-2011; 147-156 0377-8401 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/96475 |
identifier_str_mv |
Frizzo, Laureano Sebastian; Zbrun, María Virginia; Soto, Lorena Paola; Signorini Porchietto, Marcelo Lisandro; Effects of probiotics on growth performance in young calves: A meta-analysis of randomized controlled trials; Elsevier Science; Animal Feed Science and Technology; 169; 3-4; 11-2011; 147-156 0377-8401 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/journal/03778401 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.anifeedsci.2011.06.009 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
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openAccess |
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https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
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application/pdf application/pdf application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier Science |
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Elsevier Science |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
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dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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13.13397 |