Chia seed oil intake: is it beneficial for preventing cardiovascular risk factors?

Autores
Jerez, Susana Josefina; Medina, Analía; Alarcón, Gabriela del Jesús; Sierra, Liliana; Medina, Mirta
Año de publicación
2021
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
Cold pressed chia seed oils (ChO) are known for health-promoting characteristics due to the high content of omega-3 α-linolenic acid (ω-3 ALA). We investigated the influence of ChO supplementation as functional food on animal models of cardiovascular risk factors: hypercholesterolemia and metabolic syndrome (MS). Dietary intervention with ChO (equivalent to 4.8 g ALA per day) was found to improve the vascular dysfunction and mitigate the rise in plasma triglyceride (TG) levels under hypercholesterolemic conditions. However, impaired glucose tolerance was found in control ChO treated animals. In order to verify whether the effects of chia seed are the same as that of ChO, we replaced the ChO for an equivalent amount of seed. Glucose intolerance was found once again. For this reason, we carried out a new study in which the ChO intake was reduced to 3 g ALA per day, and no alterations were observed in such conditions. Thus, dietary intervention with ChO equivalent to 3 g ALA intake per day was choose to analyze the effects on the alterations that characterize the high fat diet induced-MS. ChO supplementation lowered ω-6 / ω-3 ratio, TG, blood pressure and improved endothelial function. Nevertheless, ChO worsened the high fat diet deleterious effects on visceral abdominal fat, fasting glucose and glucose tolerance. Our results support the view that dietary guidelines for treating patients with hypercholesterolemia or MS must be carefully planned, in such a way that the incorporation of ChO into the diet should be controlled and nutritional background considered.
Fil: Jerez, Susana Josefina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino | Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino; Argentina
Fil: Medina, Analía. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina
Fil: Alarcón, Gabriela del Jesús. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino | Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino; Argentina
Fil: Sierra, Liliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino | Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino; Argentina
Fil: Medina, Mirta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino | Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino; Argentina
III Conferencia internacional del grupo ValSe-Food Network y VI Simposio Chia-Link
Santiago de Chile
Chile
Universidad Central de Chile. Facultad de Ingeniería y Arquitectura
Instituto de Agroquímica y Tecnología de Alimentos
Materia
SALVIA HISPANICA
ACIDO LINOLEICO
FACTORES DE RIESGO CARDIOVASCULAR
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/156748
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/156748
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Chia seed oil intake: is it beneficial for preventing cardiovascular risk factors?Jerez, Susana JosefinaMedina, AnalíaAlarcón, Gabriela del JesúsSierra, LilianaMedina, MirtaSALVIA HISPANICAACIDO LINOLEICOFACTORES DE RIESGO CARDIOVASCULARhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Cold pressed chia seed oils (ChO) are known for health-promoting characteristics due to the high content of omega-3 α-linolenic acid (ω-3 ALA). We investigated the influence of ChO supplementation as functional food on animal models of cardiovascular risk factors: hypercholesterolemia and metabolic syndrome (MS). Dietary intervention with ChO (equivalent to 4.8 g ALA per day) was found to improve the vascular dysfunction and mitigate the rise in plasma triglyceride (TG) levels under hypercholesterolemic conditions. However, impaired glucose tolerance was found in control ChO treated animals. In order to verify whether the effects of chia seed are the same as that of ChO, we replaced the ChO for an equivalent amount of seed. Glucose intolerance was found once again. For this reason, we carried out a new study in which the ChO intake was reduced to 3 g ALA per day, and no alterations were observed in such conditions. Thus, dietary intervention with ChO equivalent to 3 g ALA intake per day was choose to analyze the effects on the alterations that characterize the high fat diet induced-MS. ChO supplementation lowered ω-6 / ω-3 ratio, TG, blood pressure and improved endothelial function. Nevertheless, ChO worsened the high fat diet deleterious effects on visceral abdominal fat, fasting glucose and glucose tolerance. Our results support the view that dietary guidelines for treating patients with hypercholesterolemia or MS must be carefully planned, in such a way that the incorporation of ChO into the diet should be controlled and nutritional background considered.Fil: Jerez, Susana Josefina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino | Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino; ArgentinaFil: Medina, Analía. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; ArgentinaFil: Alarcón, Gabriela del Jesús. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino | Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino; ArgentinaFil: Sierra, Liliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino | Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino; ArgentinaFil: Medina, Mirta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino | Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino; ArgentinaIII Conferencia internacional del grupo ValSe-Food Network y VI Simposio Chia-LinkSantiago de ChileChileUniversidad Central de Chile. Facultad de Ingeniería y ArquitecturaInstituto de Agroquímica y Tecnología de AlimentosUniversidad Central de ChileMuñoz Hernández, LoretoMonika Haros, Claudia2021info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectConferenciaBookhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/156748Chia seed oil intake: is it beneficial for preventing cardiovascular risk factors?; III Conferencia internacional del grupo ValSe-Food Network y VI Simposio Chia-Link; Santiago de Chile; Chile; 2021; 25-25978-956-330-074-1CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://bit.ly/libro-de-abstracs-conferenciaInternacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:14:04Zoai:ri.conicet.gov.ar:11336/156748instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:14:04.596CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Chia seed oil intake: is it beneficial for preventing cardiovascular risk factors?
title Chia seed oil intake: is it beneficial for preventing cardiovascular risk factors?
spellingShingle Chia seed oil intake: is it beneficial for preventing cardiovascular risk factors?
Jerez, Susana Josefina
SALVIA HISPANICA
ACIDO LINOLEICO
FACTORES DE RIESGO CARDIOVASCULAR
title_short Chia seed oil intake: is it beneficial for preventing cardiovascular risk factors?
title_full Chia seed oil intake: is it beneficial for preventing cardiovascular risk factors?
title_fullStr Chia seed oil intake: is it beneficial for preventing cardiovascular risk factors?
title_full_unstemmed Chia seed oil intake: is it beneficial for preventing cardiovascular risk factors?
title_sort Chia seed oil intake: is it beneficial for preventing cardiovascular risk factors?
dc.creator.none.fl_str_mv Jerez, Susana Josefina
Medina, Analía
Alarcón, Gabriela del Jesús
Sierra, Liliana
Medina, Mirta
author Jerez, Susana Josefina
author_facet Jerez, Susana Josefina
Medina, Analía
Alarcón, Gabriela del Jesús
Sierra, Liliana
Medina, Mirta
author_role author
author2 Medina, Analía
Alarcón, Gabriela del Jesús
Sierra, Liliana
Medina, Mirta
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Muñoz Hernández, Loreto
Monika Haros, Claudia
dc.subject.none.fl_str_mv SALVIA HISPANICA
ACIDO LINOLEICO
FACTORES DE RIESGO CARDIOVASCULAR
topic SALVIA HISPANICA
ACIDO LINOLEICO
FACTORES DE RIESGO CARDIOVASCULAR
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Cold pressed chia seed oils (ChO) are known for health-promoting characteristics due to the high content of omega-3 α-linolenic acid (ω-3 ALA). We investigated the influence of ChO supplementation as functional food on animal models of cardiovascular risk factors: hypercholesterolemia and metabolic syndrome (MS). Dietary intervention with ChO (equivalent to 4.8 g ALA per day) was found to improve the vascular dysfunction and mitigate the rise in plasma triglyceride (TG) levels under hypercholesterolemic conditions. However, impaired glucose tolerance was found in control ChO treated animals. In order to verify whether the effects of chia seed are the same as that of ChO, we replaced the ChO for an equivalent amount of seed. Glucose intolerance was found once again. For this reason, we carried out a new study in which the ChO intake was reduced to 3 g ALA per day, and no alterations were observed in such conditions. Thus, dietary intervention with ChO equivalent to 3 g ALA intake per day was choose to analyze the effects on the alterations that characterize the high fat diet induced-MS. ChO supplementation lowered ω-6 / ω-3 ratio, TG, blood pressure and improved endothelial function. Nevertheless, ChO worsened the high fat diet deleterious effects on visceral abdominal fat, fasting glucose and glucose tolerance. Our results support the view that dietary guidelines for treating patients with hypercholesterolemia or MS must be carefully planned, in such a way that the incorporation of ChO into the diet should be controlled and nutritional background considered.
Fil: Jerez, Susana Josefina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino | Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino; Argentina
Fil: Medina, Analía. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina
Fil: Alarcón, Gabriela del Jesús. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino | Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino; Argentina
Fil: Sierra, Liliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino | Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino; Argentina
Fil: Medina, Mirta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino | Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas. Grupo de Investigación y Desarrollo del Noroeste Argentino; Argentina
III Conferencia internacional del grupo ValSe-Food Network y VI Simposio Chia-Link
Santiago de Chile
Chile
Universidad Central de Chile. Facultad de Ingeniería y Arquitectura
Instituto de Agroquímica y Tecnología de Alimentos
description Cold pressed chia seed oils (ChO) are known for health-promoting characteristics due to the high content of omega-3 α-linolenic acid (ω-3 ALA). We investigated the influence of ChO supplementation as functional food on animal models of cardiovascular risk factors: hypercholesterolemia and metabolic syndrome (MS). Dietary intervention with ChO (equivalent to 4.8 g ALA per day) was found to improve the vascular dysfunction and mitigate the rise in plasma triglyceride (TG) levels under hypercholesterolemic conditions. However, impaired glucose tolerance was found in control ChO treated animals. In order to verify whether the effects of chia seed are the same as that of ChO, we replaced the ChO for an equivalent amount of seed. Glucose intolerance was found once again. For this reason, we carried out a new study in which the ChO intake was reduced to 3 g ALA per day, and no alterations were observed in such conditions. Thus, dietary intervention with ChO equivalent to 3 g ALA intake per day was choose to analyze the effects on the alterations that characterize the high fat diet induced-MS. ChO supplementation lowered ω-6 / ω-3 ratio, TG, blood pressure and improved endothelial function. Nevertheless, ChO worsened the high fat diet deleterious effects on visceral abdominal fat, fasting glucose and glucose tolerance. Our results support the view that dietary guidelines for treating patients with hypercholesterolemia or MS must be carefully planned, in such a way that the incorporation of ChO into the diet should be controlled and nutritional background considered.
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
Conferencia
Book
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
status_str publishedVersion
format conferenceObject
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/156748
Chia seed oil intake: is it beneficial for preventing cardiovascular risk factors?; III Conferencia internacional del grupo ValSe-Food Network y VI Simposio Chia-Link; Santiago de Chile; Chile; 2021; 25-25
978-956-330-074-1
CONICET Digital
CONICET
url http://hdl.handle.net/11336/156748
identifier_str_mv Chia seed oil intake: is it beneficial for preventing cardiovascular risk factors?; III Conferencia internacional del grupo ValSe-Food Network y VI Simposio Chia-Link; Santiago de Chile; Chile; 2021; 25-25
978-956-330-074-1
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://bit.ly/libro-de-abstracs-conferencia
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
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rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.coverage.none.fl_str_mv Internacional
dc.publisher.none.fl_str_mv Universidad Central de Chile
publisher.none.fl_str_mv Universidad Central de Chile
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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