Impact of probiotic Saccharomyces cerevisiae var. boulardii RC009 alone and in combination with a phytase in broiler chickens fed with antibiotic-free diets

Autores
Magnoli, Alejandra Paola; Parada, Julian; Luna, María Julieta; Corti Isgro, Maite; Escobar, Franco Matias; Fernandez, Cristian; Coniglio, María Valeria; Ortiz, María Eugenia; Wittouck, Patricia Alejandra; Watson, Santiago Juan; Cristofolini, Andrea Lorena; Cavaglieri, Lilia Reneé
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The aim of the study was to assess the impact of the Saccharomyces boulardii RC009 alone and in combination with a phytase on productive performance, biochemistry, apparent ileal phosphorus digestibility, genotoxicity and histomorphometric parameters in replacement of growth-promoting antibiotics. Two hundred and four 1-day-old male broiler chickens were weighed and redistributed in 3 replicates per treatment with 17 broilers chickens each. Throughout the 49-day experimental period, the broiler chickens were provided with both starter and finisher diets corresponding to each treatment. Treatments (T) were T1: basal diet (BD - control with AGP); T2: BD (without AGP) + S. boulardii RC009 (200g/T, 1 x 1012 CFU/T feed); T3: BD (without AGP) + S. boulardii RC009) + phytase (1000 FTU/T); T4: BD (without AGP) + phytase. The results showed that all treatments were able to improve the productive parameters studied such as DWG and DFI (P≤0.05) when compared to the control. The T3 had the highest value followed by T4 and T2. The best value of CI was obtained for T2 followed by T3 and T4. There is no effect of the probiotic or the enzyme alone or in combination on the biochemical parameters evaluated. The treatment T3 improved the weight of leg-thigh and poultry breast (P≤0.05). The digestibility of phosphorus showed significant differences between treatments (P≤0.05). The histomorphometric parameters were significantly influenced, impacting both the radio and absorptive surface areas, T3 had the best absorptive surface area. The frequency of micronucleus in bone marrow cells of broiler chickens was not affected by any of the studied treatments. The utilization of S. boulardii RC009 alone or combined with phytase notably enhanced productivity parameters, economically significant carcass weight, and histomorphometric characteristics in the small intestine. Moreover, they did not exert toxicity. These results suggest their promising potential for use either independently or in combination as substitutes for antibiotic growth promoters.
Fil: Magnoli, Alejandra Paola. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Parada, Julian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal; Argentina
Fil: Luna, María Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Corti Isgro, Maite. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal; Argentina
Fil: Escobar, Franco Matias. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal. Área de Microscopia Electrónica; Argentina
Fil: Fernandez, Cristian. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Coniglio, María Valeria. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Ortiz, María Eugenia. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Wittouck, Patricia Alejandra. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Watson, Santiago Juan. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Cristofolini, Andrea Lorena. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal. Área de Microscopia Electrónica; Argentina. Universidad Nacional de Rio Cuarto. Facultad de Agronomia y Veterinaria. Instituto de Ciencias Veterinarias. - Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Cordoba. Instituto de Ciencias Veterinarias.; Argentina
Fil: Cavaglieri, Lilia Reneé. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina
Materia
Probiotic S. boulardii RC009
Phytase
Antibiotic growth promoters
Broiler chickens
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/267068

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spelling Impact of probiotic Saccharomyces cerevisiae var. boulardii RC009 alone and in combination with a phytase in broiler chickens fed with antibiotic-free dietsMagnoli, Alejandra PaolaParada, JulianLuna, María JulietaCorti Isgro, MaiteEscobar, Franco MatiasFernandez, CristianConiglio, María ValeriaOrtiz, María EugeniaWittouck, Patricia AlejandraWatson, Santiago JuanCristofolini, Andrea LorenaCavaglieri, Lilia ReneéProbiotic S. boulardii RC009PhytaseAntibiotic growth promotersBroiler chickenshttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4The aim of the study was to assess the impact of the Saccharomyces boulardii RC009 alone and in combination with a phytase on productive performance, biochemistry, apparent ileal phosphorus digestibility, genotoxicity and histomorphometric parameters in replacement of growth-promoting antibiotics. Two hundred and four 1-day-old male broiler chickens were weighed and redistributed in 3 replicates per treatment with 17 broilers chickens each. Throughout the 49-day experimental period, the broiler chickens were provided with both starter and finisher diets corresponding to each treatment. Treatments (T) were T1: basal diet (BD - control with AGP); T2: BD (without AGP) + S. boulardii RC009 (200g/T, 1 x 1012 CFU/T feed); T3: BD (without AGP) + S. boulardii RC009) + phytase (1000 FTU/T); T4: BD (without AGP) + phytase. The results showed that all treatments were able to improve the productive parameters studied such as DWG and DFI (P≤0.05) when compared to the control. The T3 had the highest value followed by T4 and T2. The best value of CI was obtained for T2 followed by T3 and T4. There is no effect of the probiotic or the enzyme alone or in combination on the biochemical parameters evaluated. The treatment T3 improved the weight of leg-thigh and poultry breast (P≤0.05). The digestibility of phosphorus showed significant differences between treatments (P≤0.05). The histomorphometric parameters were significantly influenced, impacting both the radio and absorptive surface areas, T3 had the best absorptive surface area. The frequency of micronucleus in bone marrow cells of broiler chickens was not affected by any of the studied treatments. The utilization of S. boulardii RC009 alone or combined with phytase notably enhanced productivity parameters, economically significant carcass weight, and histomorphometric characteristics in the small intestine. Moreover, they did not exert toxicity. These results suggest their promising potential for use either independently or in combination as substitutes for antibiotic growth promoters.Fil: Magnoli, Alejandra Paola. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; ArgentinaFil: Parada, Julian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal; ArgentinaFil: Luna, María Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; ArgentinaFil: Corti Isgro, Maite. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal; ArgentinaFil: Escobar, Franco Matias. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal. Área de Microscopia Electrónica; ArgentinaFil: Fernandez, Cristian. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; ArgentinaFil: Coniglio, María Valeria. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; ArgentinaFil: Ortiz, María Eugenia. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; ArgentinaFil: Wittouck, Patricia Alejandra. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; ArgentinaFil: Watson, Santiago Juan. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; ArgentinaFil: Cristofolini, Andrea Lorena. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal. Área de Microscopia Electrónica; Argentina. Universidad Nacional de Rio Cuarto. Facultad de Agronomia y Veterinaria. Instituto de Ciencias Veterinarias. - Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Cordoba. Instituto de Ciencias Veterinarias.; ArgentinaFil: Cavaglieri, Lilia Reneé. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; ArgentinaUnique Scientific Publishers2024-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/267068Magnoli, Alejandra Paola; Parada, Julian; Luna, María Julieta; Corti Isgro, Maite; Escobar, Franco Matias; et al.; Impact of probiotic Saccharomyces cerevisiae var. boulardii RC009 alone and in combination with a phytase in broiler chickens fed with antibiotic-free diets; Unique Scientific Publishers; Agrobiological Records; 16; 2-2024; 1-102708-71822708-7190CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.47278/journal.abr/2024.006info:eu-repo/semantics/altIdentifier/url/https://agrobiologicalrecords.com/detail.php?view_id=2182info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:46:43Zoai:ri.conicet.gov.ar:11336/267068instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:46:44.118CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Impact of probiotic Saccharomyces cerevisiae var. boulardii RC009 alone and in combination with a phytase in broiler chickens fed with antibiotic-free diets
title Impact of probiotic Saccharomyces cerevisiae var. boulardii RC009 alone and in combination with a phytase in broiler chickens fed with antibiotic-free diets
spellingShingle Impact of probiotic Saccharomyces cerevisiae var. boulardii RC009 alone and in combination with a phytase in broiler chickens fed with antibiotic-free diets
Magnoli, Alejandra Paola
Probiotic S. boulardii RC009
Phytase
Antibiotic growth promoters
Broiler chickens
title_short Impact of probiotic Saccharomyces cerevisiae var. boulardii RC009 alone and in combination with a phytase in broiler chickens fed with antibiotic-free diets
title_full Impact of probiotic Saccharomyces cerevisiae var. boulardii RC009 alone and in combination with a phytase in broiler chickens fed with antibiotic-free diets
title_fullStr Impact of probiotic Saccharomyces cerevisiae var. boulardii RC009 alone and in combination with a phytase in broiler chickens fed with antibiotic-free diets
title_full_unstemmed Impact of probiotic Saccharomyces cerevisiae var. boulardii RC009 alone and in combination with a phytase in broiler chickens fed with antibiotic-free diets
title_sort Impact of probiotic Saccharomyces cerevisiae var. boulardii RC009 alone and in combination with a phytase in broiler chickens fed with antibiotic-free diets
dc.creator.none.fl_str_mv Magnoli, Alejandra Paola
Parada, Julian
Luna, María Julieta
Corti Isgro, Maite
Escobar, Franco Matias
Fernandez, Cristian
Coniglio, María Valeria
Ortiz, María Eugenia
Wittouck, Patricia Alejandra
Watson, Santiago Juan
Cristofolini, Andrea Lorena
Cavaglieri, Lilia Reneé
author Magnoli, Alejandra Paola
author_facet Magnoli, Alejandra Paola
Parada, Julian
Luna, María Julieta
Corti Isgro, Maite
Escobar, Franco Matias
Fernandez, Cristian
Coniglio, María Valeria
Ortiz, María Eugenia
Wittouck, Patricia Alejandra
Watson, Santiago Juan
Cristofolini, Andrea Lorena
Cavaglieri, Lilia Reneé
author_role author
author2 Parada, Julian
Luna, María Julieta
Corti Isgro, Maite
Escobar, Franco Matias
Fernandez, Cristian
Coniglio, María Valeria
Ortiz, María Eugenia
Wittouck, Patricia Alejandra
Watson, Santiago Juan
Cristofolini, Andrea Lorena
Cavaglieri, Lilia Reneé
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Probiotic S. boulardii RC009
Phytase
Antibiotic growth promoters
Broiler chickens
topic Probiotic S. boulardii RC009
Phytase
Antibiotic growth promoters
Broiler chickens
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv The aim of the study was to assess the impact of the Saccharomyces boulardii RC009 alone and in combination with a phytase on productive performance, biochemistry, apparent ileal phosphorus digestibility, genotoxicity and histomorphometric parameters in replacement of growth-promoting antibiotics. Two hundred and four 1-day-old male broiler chickens were weighed and redistributed in 3 replicates per treatment with 17 broilers chickens each. Throughout the 49-day experimental period, the broiler chickens were provided with both starter and finisher diets corresponding to each treatment. Treatments (T) were T1: basal diet (BD - control with AGP); T2: BD (without AGP) + S. boulardii RC009 (200g/T, 1 x 1012 CFU/T feed); T3: BD (without AGP) + S. boulardii RC009) + phytase (1000 FTU/T); T4: BD (without AGP) + phytase. The results showed that all treatments were able to improve the productive parameters studied such as DWG and DFI (P≤0.05) when compared to the control. The T3 had the highest value followed by T4 and T2. The best value of CI was obtained for T2 followed by T3 and T4. There is no effect of the probiotic or the enzyme alone or in combination on the biochemical parameters evaluated. The treatment T3 improved the weight of leg-thigh and poultry breast (P≤0.05). The digestibility of phosphorus showed significant differences between treatments (P≤0.05). The histomorphometric parameters were significantly influenced, impacting both the radio and absorptive surface areas, T3 had the best absorptive surface area. The frequency of micronucleus in bone marrow cells of broiler chickens was not affected by any of the studied treatments. The utilization of S. boulardii RC009 alone or combined with phytase notably enhanced productivity parameters, economically significant carcass weight, and histomorphometric characteristics in the small intestine. Moreover, they did not exert toxicity. These results suggest their promising potential for use either independently or in combination as substitutes for antibiotic growth promoters.
Fil: Magnoli, Alejandra Paola. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Parada, Julian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal; Argentina
Fil: Luna, María Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Corti Isgro, Maite. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal; Argentina
Fil: Escobar, Franco Matias. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal. Área de Microscopia Electrónica; Argentina
Fil: Fernandez, Cristian. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Coniglio, María Valeria. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Ortiz, María Eugenia. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Wittouck, Patricia Alejandra. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Watson, Santiago Juan. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Cristofolini, Andrea Lorena. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal. Área de Microscopia Electrónica; Argentina. Universidad Nacional de Rio Cuarto. Facultad de Agronomia y Veterinaria. Instituto de Ciencias Veterinarias. - Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Cordoba. Instituto de Ciencias Veterinarias.; Argentina
Fil: Cavaglieri, Lilia Reneé. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina
description The aim of the study was to assess the impact of the Saccharomyces boulardii RC009 alone and in combination with a phytase on productive performance, biochemistry, apparent ileal phosphorus digestibility, genotoxicity and histomorphometric parameters in replacement of growth-promoting antibiotics. Two hundred and four 1-day-old male broiler chickens were weighed and redistributed in 3 replicates per treatment with 17 broilers chickens each. Throughout the 49-day experimental period, the broiler chickens were provided with both starter and finisher diets corresponding to each treatment. Treatments (T) were T1: basal diet (BD - control with AGP); T2: BD (without AGP) + S. boulardii RC009 (200g/T, 1 x 1012 CFU/T feed); T3: BD (without AGP) + S. boulardii RC009) + phytase (1000 FTU/T); T4: BD (without AGP) + phytase. The results showed that all treatments were able to improve the productive parameters studied such as DWG and DFI (P≤0.05) when compared to the control. The T3 had the highest value followed by T4 and T2. The best value of CI was obtained for T2 followed by T3 and T4. There is no effect of the probiotic or the enzyme alone or in combination on the biochemical parameters evaluated. The treatment T3 improved the weight of leg-thigh and poultry breast (P≤0.05). The digestibility of phosphorus showed significant differences between treatments (P≤0.05). The histomorphometric parameters were significantly influenced, impacting both the radio and absorptive surface areas, T3 had the best absorptive surface area. The frequency of micronucleus in bone marrow cells of broiler chickens was not affected by any of the studied treatments. The utilization of S. boulardii RC009 alone or combined with phytase notably enhanced productivity parameters, economically significant carcass weight, and histomorphometric characteristics in the small intestine. Moreover, they did not exert toxicity. These results suggest their promising potential for use either independently or in combination as substitutes for antibiotic growth promoters.
publishDate 2024
dc.date.none.fl_str_mv 2024-02
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info:eu-repo/semantics/publishedVersion
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info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/267068
Magnoli, Alejandra Paola; Parada, Julian; Luna, María Julieta; Corti Isgro, Maite; Escobar, Franco Matias; et al.; Impact of probiotic Saccharomyces cerevisiae var. boulardii RC009 alone and in combination with a phytase in broiler chickens fed with antibiotic-free diets; Unique Scientific Publishers; Agrobiological Records; 16; 2-2024; 1-10
2708-7182
2708-7190
CONICET Digital
CONICET
url http://hdl.handle.net/11336/267068
identifier_str_mv Magnoli, Alejandra Paola; Parada, Julian; Luna, María Julieta; Corti Isgro, Maite; Escobar, Franco Matias; et al.; Impact of probiotic Saccharomyces cerevisiae var. boulardii RC009 alone and in combination with a phytase in broiler chickens fed with antibiotic-free diets; Unique Scientific Publishers; Agrobiological Records; 16; 2-2024; 1-10
2708-7182
2708-7190
CONICET Digital
CONICET
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language eng
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repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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