Harmless bacterial by products for chronic wound treatment. A clean production experience

Autores
Moreno, María Julieta; Cabrera, Carla Agostina; González, Exequiel Elías; Di Toto Blessing, Lilian Edith; Cerúsico, Nicolás Abel; Sesto Cabral, María Eugenia
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Our research team develops topic formulations based on harmless bacterial by products for chronic wound treatment. The entire scaling up process was designed to facilitate clinical trials, while Cleaner Production (CP) technologies were implemented in order to improve the process. By defining our own critical process points and increasing the efficiency of production processes, we expect reentering our own wastes in the process line, to replace expensive constituents maintaining all pharmacological properties. Four new media were designed and characterized, all activities previously reported were tested in vitro and a new quality control was designed. It is possible by reentering in the process line to minimize environmental damage, to use resources more efficiently; and to increase business profitability and competitiveness.In countries where research budgets are meager as Argentina, the tendency to innovation and improvements in the designs prototypes ´´made in Argentina´´ marks a growing trend adopted by researchers. The entering process and products were patented on INPI (National Institute of Industrial Property), INPI AR20170123114
Fil: Moreno, María Julieta. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Fil: Cabrera, Carla Agostina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Microbiología; Argentina
Fil: González, Exequiel Elías. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Fil: Di Toto Blessing, Lilian Edith. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Fil: Cerúsico, Nicolás Abel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Microbiología; Argentina
Fil: Sesto Cabral, María Eugenia. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Materia
CULTURE MEDIA DESIGN
LACTOBACILLUS PLANTARUM
CLEAN PRODUCTION
BIOFILM INHIBITION
CHRONIC WOUNDS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/149513
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/149513
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Harmless bacterial by products for chronic wound treatment. A clean production experienceMoreno, María JulietaCabrera, Carla AgostinaGonzález, Exequiel ElíasDi Toto Blessing, Lilian EdithCerúsico, Nicolás AbelSesto Cabral, María EugeniaCULTURE MEDIA DESIGNLACTOBACILLUS PLANTARUMCLEAN PRODUCTIONBIOFILM INHIBITIONCHRONIC WOUNDShttps://purl.org/becyt/ford/2.9https://purl.org/becyt/ford/2Our research team develops topic formulations based on harmless bacterial by products for chronic wound treatment. The entire scaling up process was designed to facilitate clinical trials, while Cleaner Production (CP) technologies were implemented in order to improve the process. By defining our own critical process points and increasing the efficiency of production processes, we expect reentering our own wastes in the process line, to replace expensive constituents maintaining all pharmacological properties. Four new media were designed and characterized, all activities previously reported were tested in vitro and a new quality control was designed. It is possible by reentering in the process line to minimize environmental damage, to use resources more efficiently; and to increase business profitability and competitiveness.In countries where research budgets are meager as Argentina, the tendency to innovation and improvements in the designs prototypes ´´made in Argentina´´ marks a growing trend adopted by researchers. The entering process and products were patented on INPI (National Institute of Industrial Property), INPI AR20170123114Fil: Moreno, María Julieta. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaFil: Cabrera, Carla Agostina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Microbiología; ArgentinaFil: González, Exequiel Elías. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaFil: Di Toto Blessing, Lilian Edith. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaFil: Cerúsico, Nicolás Abel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Microbiología; ArgentinaFil: Sesto Cabral, María Eugenia. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaPharma Web2018-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/149513Moreno, María Julieta; Cabrera, Carla Agostina; González, Exequiel Elías; Di Toto Blessing, Lilian Edith; Cerúsico, Nicolás Abel; et al.; Harmless bacterial by products for chronic wound treatment. A clean production experience; Pharma Web; International Journal of Pharmaceutical Research and Analysis; 3; 1; 6-2018; 1-112456-44942249-7781CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://ijprajournal.com/current-issue.php?issueid=23&title=Harmless%20Bacterial%20by%20Products%20for%20Chronic%20Wound%20Treatment.%20A%20Clean%20Production%20Experienceinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:43:26Zoai:ri.conicet.gov.ar:11336/149513instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:43:26.854CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Harmless bacterial by products for chronic wound treatment. A clean production experience
title Harmless bacterial by products for chronic wound treatment. A clean production experience
spellingShingle Harmless bacterial by products for chronic wound treatment. A clean production experience
Moreno, María Julieta
CULTURE MEDIA DESIGN
LACTOBACILLUS PLANTARUM
CLEAN PRODUCTION
BIOFILM INHIBITION
CHRONIC WOUNDS
title_short Harmless bacterial by products for chronic wound treatment. A clean production experience
title_full Harmless bacterial by products for chronic wound treatment. A clean production experience
title_fullStr Harmless bacterial by products for chronic wound treatment. A clean production experience
title_full_unstemmed Harmless bacterial by products for chronic wound treatment. A clean production experience
title_sort Harmless bacterial by products for chronic wound treatment. A clean production experience
dc.creator.none.fl_str_mv Moreno, María Julieta
Cabrera, Carla Agostina
González, Exequiel Elías
Di Toto Blessing, Lilian Edith
Cerúsico, Nicolás Abel
Sesto Cabral, María Eugenia
author Moreno, María Julieta
author_facet Moreno, María Julieta
Cabrera, Carla Agostina
González, Exequiel Elías
Di Toto Blessing, Lilian Edith
Cerúsico, Nicolás Abel
Sesto Cabral, María Eugenia
author_role author
author2 Cabrera, Carla Agostina
González, Exequiel Elías
Di Toto Blessing, Lilian Edith
Cerúsico, Nicolás Abel
Sesto Cabral, María Eugenia
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv CULTURE MEDIA DESIGN
LACTOBACILLUS PLANTARUM
CLEAN PRODUCTION
BIOFILM INHIBITION
CHRONIC WOUNDS
topic CULTURE MEDIA DESIGN
LACTOBACILLUS PLANTARUM
CLEAN PRODUCTION
BIOFILM INHIBITION
CHRONIC WOUNDS
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.9
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Our research team develops topic formulations based on harmless bacterial by products for chronic wound treatment. The entire scaling up process was designed to facilitate clinical trials, while Cleaner Production (CP) technologies were implemented in order to improve the process. By defining our own critical process points and increasing the efficiency of production processes, we expect reentering our own wastes in the process line, to replace expensive constituents maintaining all pharmacological properties. Four new media were designed and characterized, all activities previously reported were tested in vitro and a new quality control was designed. It is possible by reentering in the process line to minimize environmental damage, to use resources more efficiently; and to increase business profitability and competitiveness.In countries where research budgets are meager as Argentina, the tendency to innovation and improvements in the designs prototypes ´´made in Argentina´´ marks a growing trend adopted by researchers. The entering process and products were patented on INPI (National Institute of Industrial Property), INPI AR20170123114
Fil: Moreno, María Julieta. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Fil: Cabrera, Carla Agostina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Microbiología; Argentina
Fil: González, Exequiel Elías. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Fil: Di Toto Blessing, Lilian Edith. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Fil: Cerúsico, Nicolás Abel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Microbiología; Argentina
Fil: Sesto Cabral, María Eugenia. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
description Our research team develops topic formulations based on harmless bacterial by products for chronic wound treatment. The entire scaling up process was designed to facilitate clinical trials, while Cleaner Production (CP) technologies were implemented in order to improve the process. By defining our own critical process points and increasing the efficiency of production processes, we expect reentering our own wastes in the process line, to replace expensive constituents maintaining all pharmacological properties. Four new media were designed and characterized, all activities previously reported were tested in vitro and a new quality control was designed. It is possible by reentering in the process line to minimize environmental damage, to use resources more efficiently; and to increase business profitability and competitiveness.In countries where research budgets are meager as Argentina, the tendency to innovation and improvements in the designs prototypes ´´made in Argentina´´ marks a growing trend adopted by researchers. The entering process and products were patented on INPI (National Institute of Industrial Property), INPI AR20170123114
publishDate 2018
dc.date.none.fl_str_mv 2018-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/149513
Moreno, María Julieta; Cabrera, Carla Agostina; González, Exequiel Elías; Di Toto Blessing, Lilian Edith; Cerúsico, Nicolás Abel; et al.; Harmless bacterial by products for chronic wound treatment. A clean production experience; Pharma Web; International Journal of Pharmaceutical Research and Analysis; 3; 1; 6-2018; 1-11
2456-4494
2249-7781
CONICET Digital
CONICET
url http://hdl.handle.net/11336/149513
identifier_str_mv Moreno, María Julieta; Cabrera, Carla Agostina; González, Exequiel Elías; Di Toto Blessing, Lilian Edith; Cerúsico, Nicolás Abel; et al.; Harmless bacterial by products for chronic wound treatment. A clean production experience; Pharma Web; International Journal of Pharmaceutical Research and Analysis; 3; 1; 6-2018; 1-11
2456-4494
2249-7781
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://ijprajournal.com/current-issue.php?issueid=23&title=Harmless%20Bacterial%20by%20Products%20for%20Chronic%20Wound%20Treatment.%20A%20Clean%20Production%20Experience
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pharma Web
publisher.none.fl_str_mv Pharma Web
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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