The Potential Use of the Epigenetic Remodeler LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) as a Tool for Crop Improvement
- Autores
- Mansilla, Natanael; Ferrero, Lucia; Ariel, Federico Damian; Lucero, Leandro Exequiel
- Año de publicación
- 2023
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- The vast diversity of traits exhibited by horticultural crops largely depends upon variation in gene expression regulation. The uppermost layer of gene expression regulation is chromatin compaction. In plants, the LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) is a member of the Polycomb Repressive Complex 1 (PRC1) that controls the spreading of the H3K27me3 mark throughout the genome to regulate gene expression. Much of the epigenetic control exerted by LHP1 has been deeply explored on the model species Arabidopsis thaliana. Recent advances in melon, tomato, and soybean highlight the relevance of LHP1 in controlling the development and physiology of a plethora of traits in crops. However, whether LHP1 exerts its diverse roles through similar mechanisms and through modulating the same target genes has been overlooked. In this review, we gather a wealth of knowledge about the LHP1 mode of action, which involves a tight connection with histone marks and long noncoding RNAs to modulate gene expression. Strikingly, we found that LHP1 may be linked to H3K27me3 regulation across the plant lineage, yet, through epigenetic regulation of a distinct set of target genes. This is supported by subtle differences in subcellular LHP1 localization between species found here. In addition, we summarize the variety of developmental outputs modulated by LHP1 across land plants pinpointing its importance for plant breeding. Hence, LHP1 has probably been co-opted in different lineages to modulate diverse traits contributing to crop diversification.
Fil: Mansilla, Natanael. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina
Fil: Ferrero, Lucia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina
Fil: Ariel, Federico Damian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina
Fil: Lucero, Leandro Exequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina - Materia
-
ARABIDOPSIS
GENOME TOPOLOGY
LIKE HETEROCHROMATIN PROTEIN 1
LONG NONCODING RNA
MELON
PHYSCOMITRELLA PATENS
POLYCOMB REPRESSIVE COMPLEX 1
SOYBEAN
TOMATO - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/225733
Ver los metadatos del registro completo
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The Potential Use of the Epigenetic Remodeler LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) as a Tool for Crop ImprovementMansilla, NatanaelFerrero, LuciaAriel, Federico DamianLucero, Leandro ExequielARABIDOPSISGENOME TOPOLOGYLIKE HETEROCHROMATIN PROTEIN 1LONG NONCODING RNAMELONPHYSCOMITRELLA PATENSPOLYCOMB REPRESSIVE COMPLEX 1SOYBEANTOMATOhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The vast diversity of traits exhibited by horticultural crops largely depends upon variation in gene expression regulation. The uppermost layer of gene expression regulation is chromatin compaction. In plants, the LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) is a member of the Polycomb Repressive Complex 1 (PRC1) that controls the spreading of the H3K27me3 mark throughout the genome to regulate gene expression. Much of the epigenetic control exerted by LHP1 has been deeply explored on the model species Arabidopsis thaliana. Recent advances in melon, tomato, and soybean highlight the relevance of LHP1 in controlling the development and physiology of a plethora of traits in crops. However, whether LHP1 exerts its diverse roles through similar mechanisms and through modulating the same target genes has been overlooked. In this review, we gather a wealth of knowledge about the LHP1 mode of action, which involves a tight connection with histone marks and long noncoding RNAs to modulate gene expression. Strikingly, we found that LHP1 may be linked to H3K27me3 regulation across the plant lineage, yet, through epigenetic regulation of a distinct set of target genes. This is supported by subtle differences in subcellular LHP1 localization between species found here. In addition, we summarize the variety of developmental outputs modulated by LHP1 across land plants pinpointing its importance for plant breeding. Hence, LHP1 has probably been co-opted in different lineages to modulate diverse traits contributing to crop diversification.Fil: Mansilla, Natanael. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; ArgentinaFil: Ferrero, Lucia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; ArgentinaFil: Ariel, Federico Damian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; ArgentinaFil: Lucero, Leandro Exequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; ArgentinaMDPI2023-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/225733Mansilla, Natanael; Ferrero, Lucia; Ariel, Federico Damian; Lucero, Leandro Exequiel; The Potential Use of the Epigenetic Remodeler LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) as a Tool for Crop Improvement; MDPI; Horticulturae; 9; 2; 2-2023; 1-142311-7524CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2311-7524/9/2/199info:eu-repo/semantics/altIdentifier/doi/10.3390/horticulturae9020199info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:51:37Zoai:ri.conicet.gov.ar:11336/225733instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:51:38.116CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
The Potential Use of the Epigenetic Remodeler LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) as a Tool for Crop Improvement |
title |
The Potential Use of the Epigenetic Remodeler LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) as a Tool for Crop Improvement |
spellingShingle |
The Potential Use of the Epigenetic Remodeler LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) as a Tool for Crop Improvement Mansilla, Natanael ARABIDOPSIS GENOME TOPOLOGY LIKE HETEROCHROMATIN PROTEIN 1 LONG NONCODING RNA MELON PHYSCOMITRELLA PATENS POLYCOMB REPRESSIVE COMPLEX 1 SOYBEAN TOMATO |
title_short |
The Potential Use of the Epigenetic Remodeler LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) as a Tool for Crop Improvement |
title_full |
The Potential Use of the Epigenetic Remodeler LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) as a Tool for Crop Improvement |
title_fullStr |
The Potential Use of the Epigenetic Remodeler LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) as a Tool for Crop Improvement |
title_full_unstemmed |
The Potential Use of the Epigenetic Remodeler LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) as a Tool for Crop Improvement |
title_sort |
The Potential Use of the Epigenetic Remodeler LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) as a Tool for Crop Improvement |
dc.creator.none.fl_str_mv |
Mansilla, Natanael Ferrero, Lucia Ariel, Federico Damian Lucero, Leandro Exequiel |
author |
Mansilla, Natanael |
author_facet |
Mansilla, Natanael Ferrero, Lucia Ariel, Federico Damian Lucero, Leandro Exequiel |
author_role |
author |
author2 |
Ferrero, Lucia Ariel, Federico Damian Lucero, Leandro Exequiel |
author2_role |
author author author |
dc.subject.none.fl_str_mv |
ARABIDOPSIS GENOME TOPOLOGY LIKE HETEROCHROMATIN PROTEIN 1 LONG NONCODING RNA MELON PHYSCOMITRELLA PATENS POLYCOMB REPRESSIVE COMPLEX 1 SOYBEAN TOMATO |
topic |
ARABIDOPSIS GENOME TOPOLOGY LIKE HETEROCHROMATIN PROTEIN 1 LONG NONCODING RNA MELON PHYSCOMITRELLA PATENS POLYCOMB REPRESSIVE COMPLEX 1 SOYBEAN TOMATO |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
The vast diversity of traits exhibited by horticultural crops largely depends upon variation in gene expression regulation. The uppermost layer of gene expression regulation is chromatin compaction. In plants, the LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) is a member of the Polycomb Repressive Complex 1 (PRC1) that controls the spreading of the H3K27me3 mark throughout the genome to regulate gene expression. Much of the epigenetic control exerted by LHP1 has been deeply explored on the model species Arabidopsis thaliana. Recent advances in melon, tomato, and soybean highlight the relevance of LHP1 in controlling the development and physiology of a plethora of traits in crops. However, whether LHP1 exerts its diverse roles through similar mechanisms and through modulating the same target genes has been overlooked. In this review, we gather a wealth of knowledge about the LHP1 mode of action, which involves a tight connection with histone marks and long noncoding RNAs to modulate gene expression. Strikingly, we found that LHP1 may be linked to H3K27me3 regulation across the plant lineage, yet, through epigenetic regulation of a distinct set of target genes. This is supported by subtle differences in subcellular LHP1 localization between species found here. In addition, we summarize the variety of developmental outputs modulated by LHP1 across land plants pinpointing its importance for plant breeding. Hence, LHP1 has probably been co-opted in different lineages to modulate diverse traits contributing to crop diversification. Fil: Mansilla, Natanael. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina Fil: Ferrero, Lucia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina Fil: Ariel, Federico Damian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina Fil: Lucero, Leandro Exequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina |
description |
The vast diversity of traits exhibited by horticultural crops largely depends upon variation in gene expression regulation. The uppermost layer of gene expression regulation is chromatin compaction. In plants, the LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) is a member of the Polycomb Repressive Complex 1 (PRC1) that controls the spreading of the H3K27me3 mark throughout the genome to regulate gene expression. Much of the epigenetic control exerted by LHP1 has been deeply explored on the model species Arabidopsis thaliana. Recent advances in melon, tomato, and soybean highlight the relevance of LHP1 in controlling the development and physiology of a plethora of traits in crops. However, whether LHP1 exerts its diverse roles through similar mechanisms and through modulating the same target genes has been overlooked. In this review, we gather a wealth of knowledge about the LHP1 mode of action, which involves a tight connection with histone marks and long noncoding RNAs to modulate gene expression. Strikingly, we found that LHP1 may be linked to H3K27me3 regulation across the plant lineage, yet, through epigenetic regulation of a distinct set of target genes. This is supported by subtle differences in subcellular LHP1 localization between species found here. In addition, we summarize the variety of developmental outputs modulated by LHP1 across land plants pinpointing its importance for plant breeding. Hence, LHP1 has probably been co-opted in different lineages to modulate diverse traits contributing to crop diversification. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-02 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/225733 Mansilla, Natanael; Ferrero, Lucia; Ariel, Federico Damian; Lucero, Leandro Exequiel; The Potential Use of the Epigenetic Remodeler LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) as a Tool for Crop Improvement; MDPI; Horticulturae; 9; 2; 2-2023; 1-14 2311-7524 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/225733 |
identifier_str_mv |
Mansilla, Natanael; Ferrero, Lucia; Ariel, Federico Damian; Lucero, Leandro Exequiel; The Potential Use of the Epigenetic Remodeler LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) as a Tool for Crop Improvement; MDPI; Horticulturae; 9; 2; 2-2023; 1-14 2311-7524 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2311-7524/9/2/199 info:eu-repo/semantics/altIdentifier/doi/10.3390/horticulturae9020199 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844613586665603072 |
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13.070432 |