Ethanol-induced autonomic responses and risk taking increase in young adults with a positive family history of alcohol problems

Autores
Caneto, Florencia; Pautassi, Ricardo Marcos; Pilatti, Angelina
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The mechanisms that underlie the greater prevalence of alcohol use disorders in individuals with a positive family history (FH +) of alcohol abuse are still under investigation. These subjects may exhibit differential sensitivity to alcohol´s effects on psychomotor stimulation and impulsivity. Alcohol-induced psychomotor stimulation, measured as the heart rate (HR) response, is a proxy for the positive rewarding effects of the drug. We analyzed alcohol-induced effects on time perception (Time Production Task), risk taking (Balloon Analogue Risk Task [BART]), and HR in FH + and FH − participants. In the FH + and FH − groups, women and men received 0.6 and 0.7 g/kg alcohol, respectively. The alcohol dose yielded a breath alcohol concentration of 0.08% throughout the experiment. The control groups received placebo, and the subjective perception of alcohol intoxication was assessed. Alcohol intoxication significantly increased HR and the adjusted average number of pumps on the BART (a measure of risk taking) in FH + men and women but not in FH − participants. Behavioral impulsivity was unaffected by alcohol or a FH of alcohol abuse. FH − but not FH + participants who received alcohol reported significantly greater subjective perception of alcohol´s effects than their placebo counterparts. These results indicate that FH + individuals presented heightened sensitivity to alcohol-induced HR stimulation and alcohol-induced risk taking compared with their FH − counterparts. FH + subjects, however, were insensitive to the subjective effects of alcohol. This idiosyncratic response pattern may be a likely pathway by which a FH of alcohol problems promotes alcohol drinking.
Fil: Caneto, Florencia. Universidad Nacional de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones y Estudio sobre Cultura y Sociedad. Centro de Investigaciones de la Facultad de Psicología - Grupo Vinculado CIPSI; Argentina
Fil: Pautassi, Ricardo Marcos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
Fil: Pilatti, Angelina. Universidad Nacional de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones y Estudio sobre Cultura y Sociedad. Centro de Investigaciones de la Facultad de Psicología - Grupo Vinculado CIPSI; Argentina
Materia
ALCOHOL
FAMILY HISTORY OF ALCOHOL
HEART RATE
IMPULSIVITY
RISK TAKING
Nivel de accesibilidad
acceso abierto
Condiciones de uso
Atribución-NoComercial-CompartirIgual 2.5 Argentina (CC BY-NC-SA 2.5 AR)
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/92239
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/92239
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Ethanol-induced autonomic responses and risk taking increase in young adults with a positive family history of alcohol problemsCaneto, FlorenciaPautassi, Ricardo MarcosPilatti, AngelinaALCOHOLFAMILY HISTORY OF ALCOHOLHEART RATEIMPULSIVITYRISK TAKINGhttps://purl.org/becyt/ford/5.1https://purl.org/becyt/ford/5The mechanisms that underlie the greater prevalence of alcohol use disorders in individuals with a positive family history (FH +) of alcohol abuse are still under investigation. These subjects may exhibit differential sensitivity to alcohol´s effects on psychomotor stimulation and impulsivity. Alcohol-induced psychomotor stimulation, measured as the heart rate (HR) response, is a proxy for the positive rewarding effects of the drug. We analyzed alcohol-induced effects on time perception (Time Production Task), risk taking (Balloon Analogue Risk Task [BART]), and HR in FH + and FH − participants. In the FH + and FH − groups, women and men received 0.6 and 0.7 g/kg alcohol, respectively. The alcohol dose yielded a breath alcohol concentration of 0.08% throughout the experiment. The control groups received placebo, and the subjective perception of alcohol intoxication was assessed. Alcohol intoxication significantly increased HR and the adjusted average number of pumps on the BART (a measure of risk taking) in FH + men and women but not in FH − participants. Behavioral impulsivity was unaffected by alcohol or a FH of alcohol abuse. FH − but not FH + participants who received alcohol reported significantly greater subjective perception of alcohol´s effects than their placebo counterparts. These results indicate that FH + individuals presented heightened sensitivity to alcohol-induced HR stimulation and alcohol-induced risk taking compared with their FH − counterparts. FH + subjects, however, were insensitive to the subjective effects of alcohol. This idiosyncratic response pattern may be a likely pathway by which a FH of alcohol problems promotes alcohol drinking.Fil: Caneto, Florencia. Universidad Nacional de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones y Estudio sobre Cultura y Sociedad. Centro de Investigaciones de la Facultad de Psicología - Grupo Vinculado CIPSI; ArgentinaFil: Pautassi, Ricardo Marcos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; ArgentinaFil: Pilatti, Angelina. Universidad Nacional de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones y Estudio sobre Cultura y Sociedad. Centro de Investigaciones de la Facultad de Psicología - Grupo Vinculado CIPSI; ArgentinaPergamon-Elsevier Science Ltd2018-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/92239Caneto, Florencia; Pautassi, Ricardo Marcos; Pilatti, Angelina; Ethanol-induced autonomic responses and risk taking increase in young adults with a positive family history of alcohol problems; Pergamon-Elsevier Science Ltd; Addictive Behaviors.; 76; 1-2018; 174-1810306-4603CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0306460317302976info:eu-repo/semantics/altIdentifier/doi/10.1016/j.addbeh.2017.08.008info:eu-repo/semantics/openAccessAtribución-NoComercial-CompartirIgual 2.5 Argentina (CC BY-NC-SA 2.5 AR)https://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:00:11Zoai:ri.conicet.gov.ar:11336/92239instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:00:11.535CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Ethanol-induced autonomic responses and risk taking increase in young adults with a positive family history of alcohol problems
title Ethanol-induced autonomic responses and risk taking increase in young adults with a positive family history of alcohol problems
spellingShingle Ethanol-induced autonomic responses and risk taking increase in young adults with a positive family history of alcohol problems
Caneto, Florencia
ALCOHOL
FAMILY HISTORY OF ALCOHOL
HEART RATE
IMPULSIVITY
RISK TAKING
title_short Ethanol-induced autonomic responses and risk taking increase in young adults with a positive family history of alcohol problems
title_full Ethanol-induced autonomic responses and risk taking increase in young adults with a positive family history of alcohol problems
title_fullStr Ethanol-induced autonomic responses and risk taking increase in young adults with a positive family history of alcohol problems
title_full_unstemmed Ethanol-induced autonomic responses and risk taking increase in young adults with a positive family history of alcohol problems
title_sort Ethanol-induced autonomic responses and risk taking increase in young adults with a positive family history of alcohol problems
dc.creator.none.fl_str_mv Caneto, Florencia
Pautassi, Ricardo Marcos
Pilatti, Angelina
author Caneto, Florencia
author_facet Caneto, Florencia
Pautassi, Ricardo Marcos
Pilatti, Angelina
author_role author
author2 Pautassi, Ricardo Marcos
Pilatti, Angelina
author2_role author
author
dc.subject.none.fl_str_mv ALCOHOL
FAMILY HISTORY OF ALCOHOL
HEART RATE
IMPULSIVITY
RISK TAKING
topic ALCOHOL
FAMILY HISTORY OF ALCOHOL
HEART RATE
IMPULSIVITY
RISK TAKING
purl_subject.fl_str_mv https://purl.org/becyt/ford/5.1
https://purl.org/becyt/ford/5
dc.description.none.fl_txt_mv The mechanisms that underlie the greater prevalence of alcohol use disorders in individuals with a positive family history (FH +) of alcohol abuse are still under investigation. These subjects may exhibit differential sensitivity to alcohol´s effects on psychomotor stimulation and impulsivity. Alcohol-induced psychomotor stimulation, measured as the heart rate (HR) response, is a proxy for the positive rewarding effects of the drug. We analyzed alcohol-induced effects on time perception (Time Production Task), risk taking (Balloon Analogue Risk Task [BART]), and HR in FH + and FH − participants. In the FH + and FH − groups, women and men received 0.6 and 0.7 g/kg alcohol, respectively. The alcohol dose yielded a breath alcohol concentration of 0.08% throughout the experiment. The control groups received placebo, and the subjective perception of alcohol intoxication was assessed. Alcohol intoxication significantly increased HR and the adjusted average number of pumps on the BART (a measure of risk taking) in FH + men and women but not in FH − participants. Behavioral impulsivity was unaffected by alcohol or a FH of alcohol abuse. FH − but not FH + participants who received alcohol reported significantly greater subjective perception of alcohol´s effects than their placebo counterparts. These results indicate that FH + individuals presented heightened sensitivity to alcohol-induced HR stimulation and alcohol-induced risk taking compared with their FH − counterparts. FH + subjects, however, were insensitive to the subjective effects of alcohol. This idiosyncratic response pattern may be a likely pathway by which a FH of alcohol problems promotes alcohol drinking.
Fil: Caneto, Florencia. Universidad Nacional de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones y Estudio sobre Cultura y Sociedad. Centro de Investigaciones de la Facultad de Psicología - Grupo Vinculado CIPSI; Argentina
Fil: Pautassi, Ricardo Marcos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
Fil: Pilatti, Angelina. Universidad Nacional de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones y Estudio sobre Cultura y Sociedad. Centro de Investigaciones de la Facultad de Psicología - Grupo Vinculado CIPSI; Argentina
description The mechanisms that underlie the greater prevalence of alcohol use disorders in individuals with a positive family history (FH +) of alcohol abuse are still under investigation. These subjects may exhibit differential sensitivity to alcohol´s effects on psychomotor stimulation and impulsivity. Alcohol-induced psychomotor stimulation, measured as the heart rate (HR) response, is a proxy for the positive rewarding effects of the drug. We analyzed alcohol-induced effects on time perception (Time Production Task), risk taking (Balloon Analogue Risk Task [BART]), and HR in FH + and FH − participants. In the FH + and FH − groups, women and men received 0.6 and 0.7 g/kg alcohol, respectively. The alcohol dose yielded a breath alcohol concentration of 0.08% throughout the experiment. The control groups received placebo, and the subjective perception of alcohol intoxication was assessed. Alcohol intoxication significantly increased HR and the adjusted average number of pumps on the BART (a measure of risk taking) in FH + men and women but not in FH − participants. Behavioral impulsivity was unaffected by alcohol or a FH of alcohol abuse. FH − but not FH + participants who received alcohol reported significantly greater subjective perception of alcohol´s effects than their placebo counterparts. These results indicate that FH + individuals presented heightened sensitivity to alcohol-induced HR stimulation and alcohol-induced risk taking compared with their FH − counterparts. FH + subjects, however, were insensitive to the subjective effects of alcohol. This idiosyncratic response pattern may be a likely pathway by which a FH of alcohol problems promotes alcohol drinking.
publishDate 2018
dc.date.none.fl_str_mv 2018-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/92239
Caneto, Florencia; Pautassi, Ricardo Marcos; Pilatti, Angelina; Ethanol-induced autonomic responses and risk taking increase in young adults with a positive family history of alcohol problems; Pergamon-Elsevier Science Ltd; Addictive Behaviors.; 76; 1-2018; 174-181
0306-4603
CONICET Digital
CONICET
url http://hdl.handle.net/11336/92239
identifier_str_mv Caneto, Florencia; Pautassi, Ricardo Marcos; Pilatti, Angelina; Ethanol-induced autonomic responses and risk taking increase in young adults with a positive family history of alcohol problems; Pergamon-Elsevier Science Ltd; Addictive Behaviors.; 76; 1-2018; 174-181
0306-4603
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0306460317302976
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.addbeh.2017.08.008
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
Atribución-NoComercial-CompartirIgual 2.5 Argentina (CC BY-NC-SA 2.5 AR)
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv Atribución-NoComercial-CompartirIgual 2.5 Argentina (CC BY-NC-SA 2.5 AR)
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.993085

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