Inductively coupled plasma optical emission spectrometric determination of fifteen elements in dietary supplements: Are the concentrations declared in the labels accurate?

Autores
Marrero, Julieta; Jiménez Rebagliati, Raúl Alberto Jorge; Leiva, Emanuel; Londonio, Juan Agustín; Smichowski, Patricia Nora
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A study was carried out to establish a reliable procedure for determining 15 elements (As, Bi, Cd, Cr, Cu, Fe, Hg, Mn, Mo, Ni, Pb, Sb, Se, V and Zn) in different brands of dietary supplements purchased in Argentina and USA. Supplements were digested with HNO3 and H2O2 using an optimized microwave procedure. Inductively coupled plasma optical emission spectrometry (ICP OES) was selected for total element determination. The overall approach was tested in tablets of: (i) Se supplement, (ii) two multimineral supplements, (iii) cholesterol control tablets, (iv) multivitamins for men, and (v) a multivitamin+multimineral supplement. Arsenic, Cd and Pb concentrations were in all the analyzed samples below the detection limits for these elements (As, 1.2 µg g-1; Cd, 0.09 µg g-1 and Pb, 1.5 µg g-1). Elemental concentrations of the other elements investigated showed a great variability depending on the trade mark analyzed. Measured metal concentration ranged from 0.78±0.19 µg g-1 (Ni) to 13.5±0.7 % (Ca). Most abundant elements, detected as percentage were Ca, Mg and Fe. In general terms, the study evidenced that metal content reported by the manufacturer in labels of dietary supplements agree with found values. On the other hand, significant differences in metal concentration were found among tablets of the same bottle.
Fil: Marrero, Julieta. Comision Nacional de Energía Atómica. Gerencia de Área de Aplicaciones de la Tecnología Nuclear. Gerencia Ciclo del Combustible Nuclear; Argentina
Fil: Jiménez Rebagliati, Raúl Alberto Jorge. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); Argentina
Fil: Leiva, Emanuel. Comision Nacional de Energía Atómica. Gerencia de Área de Aplicaciones de la Tecnología Nuclear. Gerencia Ciclo del Combustible Nuclear; Argentina
Fil: Londonio, Juan Agustín. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); Argentina
Fil: Smichowski, Patricia Nora. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Dietary Supplements
Icp Oes
Metals And Metalloids
Variations Among Tablets
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/24596
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/24596
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Inductively coupled plasma optical emission spectrometric determination of fifteen elements in dietary supplements: Are the concentrations declared in the labels accurate?Marrero, JulietaJiménez Rebagliati, Raúl Alberto JorgeLeiva, EmanuelLondonio, Juan AgustínSmichowski, Patricia NoraDietary SupplementsIcp OesMetals And MetalloidsVariations Among Tabletshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1A study was carried out to establish a reliable procedure for determining 15 elements (As, Bi, Cd, Cr, Cu, Fe, Hg, Mn, Mo, Ni, Pb, Sb, Se, V and Zn) in different brands of dietary supplements purchased in Argentina and USA. Supplements were digested with HNO3 and H2O2 using an optimized microwave procedure. Inductively coupled plasma optical emission spectrometry (ICP OES) was selected for total element determination. The overall approach was tested in tablets of: (i) Se supplement, (ii) two multimineral supplements, (iii) cholesterol control tablets, (iv) multivitamins for men, and (v) a multivitamin+multimineral supplement. Arsenic, Cd and Pb concentrations were in all the analyzed samples below the detection limits for these elements (As, 1.2 µg g-1; Cd, 0.09 µg g-1 and Pb, 1.5 µg g-1). Elemental concentrations of the other elements investigated showed a great variability depending on the trade mark analyzed. Measured metal concentration ranged from 0.78±0.19 µg g-1 (Ni) to 13.5±0.7 % (Ca). Most abundant elements, detected as percentage were Ca, Mg and Fe. In general terms, the study evidenced that metal content reported by the manufacturer in labels of dietary supplements agree with found values. On the other hand, significant differences in metal concentration were found among tablets of the same bottle.Fil: Marrero, Julieta. Comision Nacional de Energía Atómica. Gerencia de Área de Aplicaciones de la Tecnología Nuclear. Gerencia Ciclo del Combustible Nuclear; ArgentinaFil: Jiménez Rebagliati, Raúl Alberto Jorge. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); ArgentinaFil: Leiva, Emanuel. Comision Nacional de Energía Atómica. Gerencia de Área de Aplicaciones de la Tecnología Nuclear. Gerencia Ciclo del Combustible Nuclear; ArgentinaFil: Londonio, Juan Agustín. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); ArgentinaFil: Smichowski, Patricia Nora. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaElsevier2013-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/24596Marrero, Julieta; Jiménez Rebagliati, Raúl Alberto Jorge; Leiva, Emanuel; Londonio, Juan Agustín; Smichowski, Patricia Nora; Inductively coupled plasma optical emission spectrometric determination of fifteen elements in dietary supplements: Are the concentrations declared in the labels accurate?; Elsevier; Microchemical Journal; 108; 1-2013; 81-860026-265XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0026265X13000027info:eu-repo/semantics/altIdentifier/doi/10.1016/j.microc.2012.12.013info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:56:05Zoai:ri.conicet.gov.ar:11336/24596instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:56:05.644CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Inductively coupled plasma optical emission spectrometric determination of fifteen elements in dietary supplements: Are the concentrations declared in the labels accurate?
title Inductively coupled plasma optical emission spectrometric determination of fifteen elements in dietary supplements: Are the concentrations declared in the labels accurate?
spellingShingle Inductively coupled plasma optical emission spectrometric determination of fifteen elements in dietary supplements: Are the concentrations declared in the labels accurate?
Marrero, Julieta
Dietary Supplements
Icp Oes
Metals And Metalloids
Variations Among Tablets
title_short Inductively coupled plasma optical emission spectrometric determination of fifteen elements in dietary supplements: Are the concentrations declared in the labels accurate?
title_full Inductively coupled plasma optical emission spectrometric determination of fifteen elements in dietary supplements: Are the concentrations declared in the labels accurate?
title_fullStr Inductively coupled plasma optical emission spectrometric determination of fifteen elements in dietary supplements: Are the concentrations declared in the labels accurate?
title_full_unstemmed Inductively coupled plasma optical emission spectrometric determination of fifteen elements in dietary supplements: Are the concentrations declared in the labels accurate?
title_sort Inductively coupled plasma optical emission spectrometric determination of fifteen elements in dietary supplements: Are the concentrations declared in the labels accurate?
dc.creator.none.fl_str_mv Marrero, Julieta
Jiménez Rebagliati, Raúl Alberto Jorge
Leiva, Emanuel
Londonio, Juan Agustín
Smichowski, Patricia Nora
author Marrero, Julieta
author_facet Marrero, Julieta
Jiménez Rebagliati, Raúl Alberto Jorge
Leiva, Emanuel
Londonio, Juan Agustín
Smichowski, Patricia Nora
author_role author
author2 Jiménez Rebagliati, Raúl Alberto Jorge
Leiva, Emanuel
Londonio, Juan Agustín
Smichowski, Patricia Nora
author2_role author
author
author
author
dc.subject.none.fl_str_mv Dietary Supplements
Icp Oes
Metals And Metalloids
Variations Among Tablets
topic Dietary Supplements
Icp Oes
Metals And Metalloids
Variations Among Tablets
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A study was carried out to establish a reliable procedure for determining 15 elements (As, Bi, Cd, Cr, Cu, Fe, Hg, Mn, Mo, Ni, Pb, Sb, Se, V and Zn) in different brands of dietary supplements purchased in Argentina and USA. Supplements were digested with HNO3 and H2O2 using an optimized microwave procedure. Inductively coupled plasma optical emission spectrometry (ICP OES) was selected for total element determination. The overall approach was tested in tablets of: (i) Se supplement, (ii) two multimineral supplements, (iii) cholesterol control tablets, (iv) multivitamins for men, and (v) a multivitamin+multimineral supplement. Arsenic, Cd and Pb concentrations were in all the analyzed samples below the detection limits for these elements (As, 1.2 µg g-1; Cd, 0.09 µg g-1 and Pb, 1.5 µg g-1). Elemental concentrations of the other elements investigated showed a great variability depending on the trade mark analyzed. Measured metal concentration ranged from 0.78±0.19 µg g-1 (Ni) to 13.5±0.7 % (Ca). Most abundant elements, detected as percentage were Ca, Mg and Fe. In general terms, the study evidenced that metal content reported by the manufacturer in labels of dietary supplements agree with found values. On the other hand, significant differences in metal concentration were found among tablets of the same bottle.
Fil: Marrero, Julieta. Comision Nacional de Energía Atómica. Gerencia de Área de Aplicaciones de la Tecnología Nuclear. Gerencia Ciclo del Combustible Nuclear; Argentina
Fil: Jiménez Rebagliati, Raúl Alberto Jorge. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); Argentina
Fil: Leiva, Emanuel. Comision Nacional de Energía Atómica. Gerencia de Área de Aplicaciones de la Tecnología Nuclear. Gerencia Ciclo del Combustible Nuclear; Argentina
Fil: Londonio, Juan Agustín. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); Argentina
Fil: Smichowski, Patricia Nora. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description A study was carried out to establish a reliable procedure for determining 15 elements (As, Bi, Cd, Cr, Cu, Fe, Hg, Mn, Mo, Ni, Pb, Sb, Se, V and Zn) in different brands of dietary supplements purchased in Argentina and USA. Supplements were digested with HNO3 and H2O2 using an optimized microwave procedure. Inductively coupled plasma optical emission spectrometry (ICP OES) was selected for total element determination. The overall approach was tested in tablets of: (i) Se supplement, (ii) two multimineral supplements, (iii) cholesterol control tablets, (iv) multivitamins for men, and (v) a multivitamin+multimineral supplement. Arsenic, Cd and Pb concentrations were in all the analyzed samples below the detection limits for these elements (As, 1.2 µg g-1; Cd, 0.09 µg g-1 and Pb, 1.5 µg g-1). Elemental concentrations of the other elements investigated showed a great variability depending on the trade mark analyzed. Measured metal concentration ranged from 0.78±0.19 µg g-1 (Ni) to 13.5±0.7 % (Ca). Most abundant elements, detected as percentage were Ca, Mg and Fe. In general terms, the study evidenced that metal content reported by the manufacturer in labels of dietary supplements agree with found values. On the other hand, significant differences in metal concentration were found among tablets of the same bottle.
publishDate 2013
dc.date.none.fl_str_mv 2013-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/24596
Marrero, Julieta; Jiménez Rebagliati, Raúl Alberto Jorge; Leiva, Emanuel; Londonio, Juan Agustín; Smichowski, Patricia Nora; Inductively coupled plasma optical emission spectrometric determination of fifteen elements in dietary supplements: Are the concentrations declared in the labels accurate?; Elsevier; Microchemical Journal; 108; 1-2013; 81-86
0026-265X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/24596
identifier_str_mv Marrero, Julieta; Jiménez Rebagliati, Raúl Alberto Jorge; Leiva, Emanuel; Londonio, Juan Agustín; Smichowski, Patricia Nora; Inductively coupled plasma optical emission spectrometric determination of fifteen elements in dietary supplements: Are the concentrations declared in the labels accurate?; Elsevier; Microchemical Journal; 108; 1-2013; 81-86
0026-265X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0026265X13000027
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.microc.2012.12.013
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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