Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom

Autores
Peichoto, María Elisa; Paes Leme, Adriana F.; Pauletti, Bianca A.; Correia Batista, Isabel; Mackessy, Stephen P.; Acosta, Ofelia Cristina; Santoro, Marcelo Larami
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Patago-calcium markedly enhanced the azocaseinolytic activity of patagonfibrase. Our findings contribute to the understanding of the structural and mechanistic bases of this family of metalloenzymes that are widely distributed among snake venoms, demonstrating that important post-translational modifications such as proteolysis can also contribute to the diversity and complexity of proteins found in rear-fanged snake venoms.
Fil: Peichoto, María Elisa. Universidad Nacional del Nordeste. Facultad de Ciencias Veterinarias; Argentina. Instituto Butantan. Laboratório de Fisiopatologia; Brasil. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; Argentina
Fil: Paes Leme, Adriana F.. Centro Nacional de Pesquisa Em Energia E Materiais; Brasil
Fil: Pauletti, Bianca A.. Centro Nacional de Pesquisa Em Energia E Materiais; Brasil
Fil: Correia Batista, Isabel. Instituto Butantan. Laboratório de Bioquímica e Biofísica; Brasil
Fil: Mackessy, Stephen P.. University of Northern Colorado; Estados Unidos
Fil: Acosta, Ofelia Cristina. Universidad Nacional del Nordeste. Facultad de Cs.veterinarias. Departamento de Clinica. Cátedra de Farmacología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; Argentina
Fil: Santoro, Marcelo Larami. Instituto Butantan. Laboratório de Fisiopatologia; Brasil
Materia
AUTODEGRADATION
COLUBRIDAE
METALLOPROTEINASE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/58642
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venomPeichoto, María ElisaPaes Leme, Adriana F.Pauletti, Bianca A.Correia Batista, IsabelMackessy, Stephen P.Acosta, Ofelia CristinaSantoro, Marcelo LaramiAUTODEGRADATIONCOLUBRIDAEMETALLOPROTEINASEhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Patago-calcium markedly enhanced the azocaseinolytic activity of patagonfibrase. Our findings contribute to the understanding of the structural and mechanistic bases of this family of metalloenzymes that are widely distributed among snake venoms, demonstrating that important post-translational modifications such as proteolysis can also contribute to the diversity and complexity of proteins found in rear-fanged snake venoms.Fil: Peichoto, María Elisa. Universidad Nacional del Nordeste. Facultad de Ciencias Veterinarias; Argentina. Instituto Butantan. Laboratório de Fisiopatologia; Brasil. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; ArgentinaFil: Paes Leme, Adriana F.. Centro Nacional de Pesquisa Em Energia E Materiais; BrasilFil: Pauletti, Bianca A.. Centro Nacional de Pesquisa Em Energia E Materiais; BrasilFil: Correia Batista, Isabel. Instituto Butantan. Laboratório de Bioquímica e Biofísica; BrasilFil: Mackessy, Stephen P.. University of Northern Colorado; Estados UnidosFil: Acosta, Ofelia Cristina. Universidad Nacional del Nordeste. Facultad de Cs.veterinarias. Departamento de Clinica. Cátedra de Farmacología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; ArgentinaFil: Santoro, Marcelo Larami. Instituto Butantan. Laboratório de Fisiopatologia; BrasilElsevier Science2010-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/58642Peichoto, María Elisa; Paes Leme, Adriana F.; Pauletti, Bianca A.; Correia Batista, Isabel; Mackessy, Stephen P.; et al.; Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom; Elsevier Science; Biochimica Et Biophysica Acta-proteins And Proteomics; 1804; 9; 9-2010; 1937-19421570-9639CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.bbapap.2010.06.005info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1570963910001639info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:37:36Zoai:ri.conicet.gov.ar:11336/58642instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:37:36.907CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom
title Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom
spellingShingle Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom
Peichoto, María Elisa
AUTODEGRADATION
COLUBRIDAE
METALLOPROTEINASE
title_short Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom
title_full Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom
title_fullStr Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom
title_full_unstemmed Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom
title_sort Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom
dc.creator.none.fl_str_mv Peichoto, María Elisa
Paes Leme, Adriana F.
Pauletti, Bianca A.
Correia Batista, Isabel
Mackessy, Stephen P.
Acosta, Ofelia Cristina
Santoro, Marcelo Larami
author Peichoto, María Elisa
author_facet Peichoto, María Elisa
Paes Leme, Adriana F.
Pauletti, Bianca A.
Correia Batista, Isabel
Mackessy, Stephen P.
Acosta, Ofelia Cristina
Santoro, Marcelo Larami
author_role author
author2 Paes Leme, Adriana F.
Pauletti, Bianca A.
Correia Batista, Isabel
Mackessy, Stephen P.
Acosta, Ofelia Cristina
Santoro, Marcelo Larami
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv AUTODEGRADATION
COLUBRIDAE
METALLOPROTEINASE
topic AUTODEGRADATION
COLUBRIDAE
METALLOPROTEINASE
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Patago-calcium markedly enhanced the azocaseinolytic activity of patagonfibrase. Our findings contribute to the understanding of the structural and mechanistic bases of this family of metalloenzymes that are widely distributed among snake venoms, demonstrating that important post-translational modifications such as proteolysis can also contribute to the diversity and complexity of proteins found in rear-fanged snake venoms.
Fil: Peichoto, María Elisa. Universidad Nacional del Nordeste. Facultad de Ciencias Veterinarias; Argentina. Instituto Butantan. Laboratório de Fisiopatologia; Brasil. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; Argentina
Fil: Paes Leme, Adriana F.. Centro Nacional de Pesquisa Em Energia E Materiais; Brasil
Fil: Pauletti, Bianca A.. Centro Nacional de Pesquisa Em Energia E Materiais; Brasil
Fil: Correia Batista, Isabel. Instituto Butantan. Laboratório de Bioquímica e Biofísica; Brasil
Fil: Mackessy, Stephen P.. University of Northern Colorado; Estados Unidos
Fil: Acosta, Ofelia Cristina. Universidad Nacional del Nordeste. Facultad de Cs.veterinarias. Departamento de Clinica. Cátedra de Farmacología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; Argentina
Fil: Santoro, Marcelo Larami. Instituto Butantan. Laboratório de Fisiopatologia; Brasil
description Patago-calcium markedly enhanced the azocaseinolytic activity of patagonfibrase. Our findings contribute to the understanding of the structural and mechanistic bases of this family of metalloenzymes that are widely distributed among snake venoms, demonstrating that important post-translational modifications such as proteolysis can also contribute to the diversity and complexity of proteins found in rear-fanged snake venoms.
publishDate 2010
dc.date.none.fl_str_mv 2010-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/58642
Peichoto, María Elisa; Paes Leme, Adriana F.; Pauletti, Bianca A.; Correia Batista, Isabel; Mackessy, Stephen P.; et al.; Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom; Elsevier Science; Biochimica Et Biophysica Acta-proteins And Proteomics; 1804; 9; 9-2010; 1937-1942
1570-9639
CONICET Digital
CONICET
url http://hdl.handle.net/11336/58642
identifier_str_mv Peichoto, María Elisa; Paes Leme, Adriana F.; Pauletti, Bianca A.; Correia Batista, Isabel; Mackessy, Stephen P.; et al.; Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom; Elsevier Science; Biochimica Et Biophysica Acta-proteins And Proteomics; 1804; 9; 9-2010; 1937-1942
1570-9639
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.bbapap.2010.06.005
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1570963910001639
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846082849680130048
score 13.22299

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