Insights into the Anti-Adipogenic and Anti-Inflammatory Potentialities of Probiotics against Obesity
- Autores
- Kober, A. K. M. Humayun; Saha, Sudeb; Ayyash, Mutamed; Namai, Fu; Nishiyama, Keita; Yoda, Kazutoyo; Villena, Julio Cesar; Kitazawa, Haruki
- Año de publicación
- 2024
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Functional foods with probiotics are safe and effective dietary supplements to improve overweight and obesity. Thus, altering the intestinal microflora may be an effective approach for controlling or preventing obesity. This review aims to summarize the experimental method used to study probiotics and obesity, and recent advances in probiotics against obesity. In particular, we focused on studies (in vitro and in vivo) that used probiotics to treat obesity and its associated comorbidities. Several in vitro and in vivo (animal and human clinical) studies conducted with different bacterial species/strains have reported that probiotics promote anti-obesity effects by suppressing the differentiation of pre-adipocytes through immune cell activation, maintaining the Th1/Th2 cytokine balance, altering the intestinal microbiota composition, reducing the lipid profile, and regulating energy metabolism. Most studies on probiotics and obesity have shown that probiotics are responsible for a notable reduction in weight gain and body mass index. It also increases the levels of anti-inflammatory adipokines and decreases those of pro-inflammatory adipokines in the blood, which are responsible for the regulation of glucose and fatty acid breakdown. Furthermore, probiotics effectively increase insulin sensitivity and decrease systemic inflammation. Taken together, the intestinal microbiota profile found in overweight individuals can be modified by probiotic supplementation which can create a promising environment for weight loss along enhancing levels of adiponectin and decreasing leptin, tumor necrosis factor (TNF)-α, interleukin (IL)-6, monocyte chemotactic protein (MCP)-1, and transforming growth factor (TGF)-β on human health.
Fil: Kober, A. K. M. Humayun. Chittagong Veterinary And Animal Sciences University; Bangladesh
Fil: Saha, Sudeb. Sylhet Agricultural University; Bangladesh. Tohoku University; Japón
Fil: Ayyash, Mutamed. United Arab Emirates University; Emiratos Árabes Unidos
Fil: Namai, Fu. Tohoku University; Japón
Fil: Nishiyama, Keita. Takanashi Milk Products Co.; Japón
Fil: Yoda, Kazutoyo. Takanashi Milk Products Co.; Japón
Fil: Villena, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina
Fil: Kitazawa, Haruki. Tohoku University; Japón - Materia
-
OBESITY
PROBIOTICS
ANTI-INFLAMMATORY ADIPOKINES
PRO-INFLAMMATORY ADIPOKINES
ADIPOCYTES - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/260584
Ver los metadatos del registro completo
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Insights into the Anti-Adipogenic and Anti-Inflammatory Potentialities of Probiotics against ObesityKober, A. K. M. HumayunSaha, SudebAyyash, MutamedNamai, FuNishiyama, KeitaYoda, KazutoyoVillena, Julio CesarKitazawa, HarukiOBESITYPROBIOTICSANTI-INFLAMMATORY ADIPOKINESPRO-INFLAMMATORY ADIPOKINESADIPOCYTEShttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Functional foods with probiotics are safe and effective dietary supplements to improve overweight and obesity. Thus, altering the intestinal microflora may be an effective approach for controlling or preventing obesity. This review aims to summarize the experimental method used to study probiotics and obesity, and recent advances in probiotics against obesity. In particular, we focused on studies (in vitro and in vivo) that used probiotics to treat obesity and its associated comorbidities. Several in vitro and in vivo (animal and human clinical) studies conducted with different bacterial species/strains have reported that probiotics promote anti-obesity effects by suppressing the differentiation of pre-adipocytes through immune cell activation, maintaining the Th1/Th2 cytokine balance, altering the intestinal microbiota composition, reducing the lipid profile, and regulating energy metabolism. Most studies on probiotics and obesity have shown that probiotics are responsible for a notable reduction in weight gain and body mass index. It also increases the levels of anti-inflammatory adipokines and decreases those of pro-inflammatory adipokines in the blood, which are responsible for the regulation of glucose and fatty acid breakdown. Furthermore, probiotics effectively increase insulin sensitivity and decrease systemic inflammation. Taken together, the intestinal microbiota profile found in overweight individuals can be modified by probiotic supplementation which can create a promising environment for weight loss along enhancing levels of adiponectin and decreasing leptin, tumor necrosis factor (TNF)-α, interleukin (IL)-6, monocyte chemotactic protein (MCP)-1, and transforming growth factor (TGF)-β on human health.Fil: Kober, A. K. M. Humayun. Chittagong Veterinary And Animal Sciences University; BangladeshFil: Saha, Sudeb. Sylhet Agricultural University; Bangladesh. Tohoku University; JapónFil: Ayyash, Mutamed. United Arab Emirates University; Emiratos Árabes UnidosFil: Namai, Fu. Tohoku University; JapónFil: Nishiyama, Keita. Takanashi Milk Products Co.; JapónFil: Yoda, Kazutoyo. Takanashi Milk Products Co.; JapónFil: Villena, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaFil: Kitazawa, Haruki. Tohoku University; JapónMultidisciplinary Digital Publishing Institute2024-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/260584Kober, A. K. M. Humayun; Saha, Sudeb; Ayyash, Mutamed; Namai, Fu; Nishiyama, Keita; et al.; Insights into the Anti-Adipogenic and Anti-Inflammatory Potentialities of Probiotics against Obesity; Multidisciplinary Digital Publishing Institute; Nutrients; 16; 9; 4-2024; 1-222072-6643CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2072-6643/16/9/1373info:eu-repo/semantics/altIdentifier/doi/10.3390/nu16091373info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:44:35Zoai:ri.conicet.gov.ar:11336/260584instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:44:36.236CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Insights into the Anti-Adipogenic and Anti-Inflammatory Potentialities of Probiotics against Obesity |
title |
Insights into the Anti-Adipogenic and Anti-Inflammatory Potentialities of Probiotics against Obesity |
spellingShingle |
Insights into the Anti-Adipogenic and Anti-Inflammatory Potentialities of Probiotics against Obesity Kober, A. K. M. Humayun OBESITY PROBIOTICS ANTI-INFLAMMATORY ADIPOKINES PRO-INFLAMMATORY ADIPOKINES ADIPOCYTES |
title_short |
Insights into the Anti-Adipogenic and Anti-Inflammatory Potentialities of Probiotics against Obesity |
title_full |
Insights into the Anti-Adipogenic and Anti-Inflammatory Potentialities of Probiotics against Obesity |
title_fullStr |
Insights into the Anti-Adipogenic and Anti-Inflammatory Potentialities of Probiotics against Obesity |
title_full_unstemmed |
Insights into the Anti-Adipogenic and Anti-Inflammatory Potentialities of Probiotics against Obesity |
title_sort |
Insights into the Anti-Adipogenic and Anti-Inflammatory Potentialities of Probiotics against Obesity |
dc.creator.none.fl_str_mv |
Kober, A. K. M. Humayun Saha, Sudeb Ayyash, Mutamed Namai, Fu Nishiyama, Keita Yoda, Kazutoyo Villena, Julio Cesar Kitazawa, Haruki |
author |
Kober, A. K. M. Humayun |
author_facet |
Kober, A. K. M. Humayun Saha, Sudeb Ayyash, Mutamed Namai, Fu Nishiyama, Keita Yoda, Kazutoyo Villena, Julio Cesar Kitazawa, Haruki |
author_role |
author |
author2 |
Saha, Sudeb Ayyash, Mutamed Namai, Fu Nishiyama, Keita Yoda, Kazutoyo Villena, Julio Cesar Kitazawa, Haruki |
author2_role |
author author author author author author author |
dc.subject.none.fl_str_mv |
OBESITY PROBIOTICS ANTI-INFLAMMATORY ADIPOKINES PRO-INFLAMMATORY ADIPOKINES ADIPOCYTES |
topic |
OBESITY PROBIOTICS ANTI-INFLAMMATORY ADIPOKINES PRO-INFLAMMATORY ADIPOKINES ADIPOCYTES |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.1 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
Functional foods with probiotics are safe and effective dietary supplements to improve overweight and obesity. Thus, altering the intestinal microflora may be an effective approach for controlling or preventing obesity. This review aims to summarize the experimental method used to study probiotics and obesity, and recent advances in probiotics against obesity. In particular, we focused on studies (in vitro and in vivo) that used probiotics to treat obesity and its associated comorbidities. Several in vitro and in vivo (animal and human clinical) studies conducted with different bacterial species/strains have reported that probiotics promote anti-obesity effects by suppressing the differentiation of pre-adipocytes through immune cell activation, maintaining the Th1/Th2 cytokine balance, altering the intestinal microbiota composition, reducing the lipid profile, and regulating energy metabolism. Most studies on probiotics and obesity have shown that probiotics are responsible for a notable reduction in weight gain and body mass index. It also increases the levels of anti-inflammatory adipokines and decreases those of pro-inflammatory adipokines in the blood, which are responsible for the regulation of glucose and fatty acid breakdown. Furthermore, probiotics effectively increase insulin sensitivity and decrease systemic inflammation. Taken together, the intestinal microbiota profile found in overweight individuals can be modified by probiotic supplementation which can create a promising environment for weight loss along enhancing levels of adiponectin and decreasing leptin, tumor necrosis factor (TNF)-α, interleukin (IL)-6, monocyte chemotactic protein (MCP)-1, and transforming growth factor (TGF)-β on human health. Fil: Kober, A. K. M. Humayun. Chittagong Veterinary And Animal Sciences University; Bangladesh Fil: Saha, Sudeb. Sylhet Agricultural University; Bangladesh. Tohoku University; Japón Fil: Ayyash, Mutamed. United Arab Emirates University; Emiratos Árabes Unidos Fil: Namai, Fu. Tohoku University; Japón Fil: Nishiyama, Keita. Takanashi Milk Products Co.; Japón Fil: Yoda, Kazutoyo. Takanashi Milk Products Co.; Japón Fil: Villena, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina Fil: Kitazawa, Haruki. Tohoku University; Japón |
description |
Functional foods with probiotics are safe and effective dietary supplements to improve overweight and obesity. Thus, altering the intestinal microflora may be an effective approach for controlling or preventing obesity. This review aims to summarize the experimental method used to study probiotics and obesity, and recent advances in probiotics against obesity. In particular, we focused on studies (in vitro and in vivo) that used probiotics to treat obesity and its associated comorbidities. Several in vitro and in vivo (animal and human clinical) studies conducted with different bacterial species/strains have reported that probiotics promote anti-obesity effects by suppressing the differentiation of pre-adipocytes through immune cell activation, maintaining the Th1/Th2 cytokine balance, altering the intestinal microbiota composition, reducing the lipid profile, and regulating energy metabolism. Most studies on probiotics and obesity have shown that probiotics are responsible for a notable reduction in weight gain and body mass index. It also increases the levels of anti-inflammatory adipokines and decreases those of pro-inflammatory adipokines in the blood, which are responsible for the regulation of glucose and fatty acid breakdown. Furthermore, probiotics effectively increase insulin sensitivity and decrease systemic inflammation. Taken together, the intestinal microbiota profile found in overweight individuals can be modified by probiotic supplementation which can create a promising environment for weight loss along enhancing levels of adiponectin and decreasing leptin, tumor necrosis factor (TNF)-α, interleukin (IL)-6, monocyte chemotactic protein (MCP)-1, and transforming growth factor (TGF)-β on human health. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-04 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/260584 Kober, A. K. M. Humayun; Saha, Sudeb; Ayyash, Mutamed; Namai, Fu; Nishiyama, Keita; et al.; Insights into the Anti-Adipogenic and Anti-Inflammatory Potentialities of Probiotics against Obesity; Multidisciplinary Digital Publishing Institute; Nutrients; 16; 9; 4-2024; 1-22 2072-6643 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/260584 |
identifier_str_mv |
Kober, A. K. M. Humayun; Saha, Sudeb; Ayyash, Mutamed; Namai, Fu; Nishiyama, Keita; et al.; Insights into the Anti-Adipogenic and Anti-Inflammatory Potentialities of Probiotics against Obesity; Multidisciplinary Digital Publishing Institute; Nutrients; 16; 9; 4-2024; 1-22 2072-6643 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2072-6643/16/9/1373 info:eu-repo/semantics/altIdentifier/doi/10.3390/nu16091373 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Multidisciplinary Digital Publishing Institute |
publisher.none.fl_str_mv |
Multidisciplinary Digital Publishing Institute |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
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CONICET Digital (CONICET) |
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Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1842268677511053312 |
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13.13397 |