Pharmacological Interactions in Patients with Epileptic Crisis Hospitalized in a Public Institution

Autores
Montiel, Carolina Soledad; Troche, María Ignacia; Marín, Lupe; Lugo de Ortellad, Gladys; Samaniego, Lourdes; Marín, Gustavo H.; Maidana, Gladys Mabel
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Objective: The present study was carried out to evaluate the potential pharmacological interactions in a group of adult hospitalized patients due to an epileptic crisis. Methodology: Descriptive-analytical study. Data was obtained from medical records of hospitalized patients during the investigation period. Results: 937 patients were enrolled in the study, 143 different drug interactions were detected in 35 patients, which involved 46 medicines administered. The interactions were classified according to their theoretical relevance in serious (18.88%), significant (51.04%) and minor (30.07%). 48.57% of patients presented drug interactions with nutrients. Conclusion: The intervention of a multidisciplinary team is necessary for the management of these patients, which includes nutritionists specially trained in aspects of pharmacokinetics and pharmacodynamics, in order to minimize the incidence of pharmacological interactions.
Materia
Ciencias Médicas
Pharmacological interactions
Nutrients
Hospitalization
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-nd/3.0/
Repositorio
CIC Digital (CICBA)
Institución
Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
OAI Identificador
oai:digital.cic.gba.gob.ar:11746/10833

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oai_identifier_str oai:digital.cic.gba.gob.ar:11746/10833
network_acronym_str CICBA
repository_id_str 9441
network_name_str CIC Digital (CICBA)
spelling Pharmacological Interactions in Patients with Epileptic Crisis Hospitalized in a Public InstitutionMontiel, Carolina SoledadTroche, María IgnaciaMarín, LupeLugo de Ortellad, GladysSamaniego, LourdesMarín, Gustavo H.Maidana, Gladys MabelCiencias MédicasPharmacological interactionsNutrientsHospitalizationObjective: The present study was carried out to evaluate the potential pharmacological interactions in a group of adult hospitalized patients due to an epileptic crisis. Methodology: Descriptive-analytical study. Data was obtained from medical records of hospitalized patients during the investigation period. Results: 937 patients were enrolled in the study, 143 different drug interactions were detected in 35 patients, which involved 46 medicines administered. The interactions were classified according to their theoretical relevance in serious (18.88%), significant (51.04%) and minor (30.07%). 48.57% of patients presented drug interactions with nutrients. Conclusion: The intervention of a multidisciplinary team is necessary for the management of these patients, which includes nutritionists specially trained in aspects of pharmacokinetics and pharmacodynamics, in order to minimize the incidence of pharmacological interactions.2020-01-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://digital.cic.gba.gob.ar/handle/11746/10833enginfo:eu-repo/semantics/altIdentifier/issn/2640-0820info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/3.0/reponame:CIC Digital (CICBA)instname:Comisión de Investigaciones Científicas de la Provincia de Buenos Airesinstacron:CICBA2025-09-04T09:42:56Zoai:digital.cic.gba.gob.ar:11746/10833Institucionalhttp://digital.cic.gba.gob.arOrganismo científico-tecnológicoNo correspondehttp://digital.cic.gba.gob.ar/oai/snrdmarisa.degiusti@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:94412025-09-04 09:42:56.914CIC Digital (CICBA) - Comisión de Investigaciones Científicas de la Provincia de Buenos Airesfalse
dc.title.none.fl_str_mv Pharmacological Interactions in Patients with Epileptic Crisis Hospitalized in a Public Institution
title Pharmacological Interactions in Patients with Epileptic Crisis Hospitalized in a Public Institution
spellingShingle Pharmacological Interactions in Patients with Epileptic Crisis Hospitalized in a Public Institution
Montiel, Carolina Soledad
Ciencias Médicas
Pharmacological interactions
Nutrients
Hospitalization
title_short Pharmacological Interactions in Patients with Epileptic Crisis Hospitalized in a Public Institution
title_full Pharmacological Interactions in Patients with Epileptic Crisis Hospitalized in a Public Institution
title_fullStr Pharmacological Interactions in Patients with Epileptic Crisis Hospitalized in a Public Institution
title_full_unstemmed Pharmacological Interactions in Patients with Epileptic Crisis Hospitalized in a Public Institution
title_sort Pharmacological Interactions in Patients with Epileptic Crisis Hospitalized in a Public Institution
dc.creator.none.fl_str_mv Montiel, Carolina Soledad
Troche, María Ignacia
Marín, Lupe
Lugo de Ortellad, Gladys
Samaniego, Lourdes
Marín, Gustavo H.
Maidana, Gladys Mabel
author Montiel, Carolina Soledad
author_facet Montiel, Carolina Soledad
Troche, María Ignacia
Marín, Lupe
Lugo de Ortellad, Gladys
Samaniego, Lourdes
Marín, Gustavo H.
Maidana, Gladys Mabel
author_role author
author2 Troche, María Ignacia
Marín, Lupe
Lugo de Ortellad, Gladys
Samaniego, Lourdes
Marín, Gustavo H.
Maidana, Gladys Mabel
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Ciencias Médicas
Pharmacological interactions
Nutrients
Hospitalization
topic Ciencias Médicas
Pharmacological interactions
Nutrients
Hospitalization
dc.description.none.fl_txt_mv Objective: The present study was carried out to evaluate the potential pharmacological interactions in a group of adult hospitalized patients due to an epileptic crisis. Methodology: Descriptive-analytical study. Data was obtained from medical records of hospitalized patients during the investigation period. Results: 937 patients were enrolled in the study, 143 different drug interactions were detected in 35 patients, which involved 46 medicines administered. The interactions were classified according to their theoretical relevance in serious (18.88%), significant (51.04%) and minor (30.07%). 48.57% of patients presented drug interactions with nutrients. Conclusion: The intervention of a multidisciplinary team is necessary for the management of these patients, which includes nutritionists specially trained in aspects of pharmacokinetics and pharmacodynamics, in order to minimize the incidence of pharmacological interactions.
description Objective: The present study was carried out to evaluate the potential pharmacological interactions in a group of adult hospitalized patients due to an epileptic crisis. Methodology: Descriptive-analytical study. Data was obtained from medical records of hospitalized patients during the investigation period. Results: 937 patients were enrolled in the study, 143 different drug interactions were detected in 35 patients, which involved 46 medicines administered. The interactions were classified according to their theoretical relevance in serious (18.88%), significant (51.04%) and minor (30.07%). 48.57% of patients presented drug interactions with nutrients. Conclusion: The intervention of a multidisciplinary team is necessary for the management of these patients, which includes nutritionists specially trained in aspects of pharmacokinetics and pharmacodynamics, in order to minimize the incidence of pharmacological interactions.
publishDate 2020
dc.date.none.fl_str_mv 2020-01-02
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http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://digital.cic.gba.gob.ar/handle/11746/10833
url https://digital.cic.gba.gob.ar/handle/11746/10833
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/2640-0820
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/3.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/3.0/
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dc.source.none.fl_str_mv reponame:CIC Digital (CICBA)
instname:Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
instacron:CICBA
reponame_str CIC Digital (CICBA)
collection CIC Digital (CICBA)
instname_str Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
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institution CICBA
repository.name.fl_str_mv CIC Digital (CICBA) - Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
repository.mail.fl_str_mv marisa.degiusti@sedici.unlp.edu.ar
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