Impact of Mental Illnesses Treatment During the Period 1950-2020: Analysis of A Single Mental Institution, Buenos Aires, Argentina

Autores
Marín, Gustavo H.; Giangreco, Lucia; Valdez, Emilia; Heig, Melina; Kersich, Blas; Marin, Gina; Marín, Lupe
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Introduction: Mental health treatment has varied in the last century; however, the impact of these new therapeutical options is little-known. Objectives: To evaluate the impact of treatments for mental health diseases along the last decades. Methodology: retrospective, descriptive case-report study. Medical records of patients admitted to a Mental Health Institution in Buenos Aires, Argentina were evaluated over 7 decades. Variables analyzed were: age, sex, diagnosis, time of hospital stay, number of re-hospitalizations, drugs available per decade, cost of drug, cost of hospitalizations. Results: Hospitalization stay was 6.33 months, with 3.18 readmissions per patient (in the 21st century it was detected a reduction in the length of hospitalization (4.66 months) and an increase in the number of hospitalizations (4.3 hospitalizations/patient). The numer of drugs prescribed was 5.14 per patient (1.6 in the 1950s and 7.22 in the last decade). During 1950s, the most prescribed drugs were lithium and chlorpromazine, in the ’60s haloperidol; in the ‘70s benzodiazepines, haloperidol, and amitriptyline; in the ‘80s and ‘90s fluoxetine, sertraline, and BZD; from the 2000s paroxetine, risperidone, and pregabalin were added to the earlier drugs; and in the current decade new antipsychotics (olanzapine, ziprasidone, quetiapine or lurasidone), antiepileptics (lamotrigine) were included. Although diagnoses were maintained over time (schizophrenia, psychosis, bipolar disorder, dementia, depression) in the last decade, 27.7% of the hospitalized patients had dual pathology (addiction+other mental illness). Cost of drugs prescribed increased >9 times, while cost of hospitalization increased >4 times in the last decade compared to the second half of the 20th century. Conclusion: Although new drugs to treat severe mental disorders reduced side effects associate to treatment, its efficacy did not improve neither the duration of the hospital stay nor in the number of re-hospitalizations along the past 70 years; while cost of new drugs increased 9 times.
Materia
Psiquiatría
Mental
Health
Treatment
Drugs
Hospitalization
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
CIC Digital (CICBA)
Institución
Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
OAI Identificador
oai:digital.cic.gba.gob.ar:11746/10832

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network_name_str CIC Digital (CICBA)
spelling Impact of Mental Illnesses Treatment During the Period 1950-2020: Analysis of A Single Mental Institution, Buenos Aires, ArgentinaMarín, Gustavo H.Giangreco, LuciaValdez, EmiliaHeig, MelinaKersich, BlasMarin, GinaMarín, LupePsiquiatríaMentalHealthTreatmentDrugsHospitalizationIntroduction: Mental health treatment has varied in the last century; however, the impact of these new therapeutical options is little-known. Objectives: To evaluate the impact of treatments for mental health diseases along the last decades. Methodology: retrospective, descriptive case-report study. Medical records of patients admitted to a Mental Health Institution in Buenos Aires, Argentina were evaluated over 7 decades. Variables analyzed were: age, sex, diagnosis, time of hospital stay, number of re-hospitalizations, drugs available per decade, cost of drug, cost of hospitalizations. Results: Hospitalization stay was 6.33 months, with 3.18 readmissions per patient (in the 21st century it was detected a reduction in the length of hospitalization (4.66 months) and an increase in the number of hospitalizations (4.3 hospitalizations/patient). The numer of drugs prescribed was 5.14 per patient (1.6 in the 1950s and 7.22 in the last decade). During 1950s, the most prescribed drugs were lithium and chlorpromazine, in the ’60s haloperidol; in the ‘70s benzodiazepines, haloperidol, and amitriptyline; in the ‘80s and ‘90s fluoxetine, sertraline, and BZD; from the 2000s paroxetine, risperidone, and pregabalin were added to the earlier drugs; and in the current decade new antipsychotics (olanzapine, ziprasidone, quetiapine or lurasidone), antiepileptics (lamotrigine) were included. Although diagnoses were maintained over time (schizophrenia, psychosis, bipolar disorder, dementia, depression) in the last decade, 27.7% of the hospitalized patients had dual pathology (addiction+other mental illness). Cost of drugs prescribed increased >9 times, while cost of hospitalization increased >4 times in the last decade compared to the second half of the 20th century. Conclusion: Although new drugs to treat severe mental disorders reduced side effects associate to treatment, its efficacy did not improve neither the duration of the hospital stay nor in the number of re-hospitalizations along the past 70 years; while cost of new drugs increased 9 times.2020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://digital.cic.gba.gob.ar/handle/11746/10832enginfo:eu-repo/semantics/altIdentifier/doi/10.33425/2641-4317.1077info:eu-repo/semantics/altIdentifier/issn/2641-4317info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/reponame:CIC Digital (CICBA)instname:Comisión de Investigaciones Científicas de la Provincia de Buenos Airesinstacron:CICBA2025-09-04T09:43:51Zoai:digital.cic.gba.gob.ar:11746/10832Institucionalhttp://digital.cic.gba.gob.arOrganismo científico-tecnológicoNo correspondehttp://digital.cic.gba.gob.ar/oai/snrdmarisa.degiusti@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:94412025-09-04 09:43:51.733CIC Digital (CICBA) - Comisión de Investigaciones Científicas de la Provincia de Buenos Airesfalse
dc.title.none.fl_str_mv Impact of Mental Illnesses Treatment During the Period 1950-2020: Analysis of A Single Mental Institution, Buenos Aires, Argentina
title Impact of Mental Illnesses Treatment During the Period 1950-2020: Analysis of A Single Mental Institution, Buenos Aires, Argentina
spellingShingle Impact of Mental Illnesses Treatment During the Period 1950-2020: Analysis of A Single Mental Institution, Buenos Aires, Argentina
Marín, Gustavo H.
Psiquiatría
Mental
Health
Treatment
Drugs
Hospitalization
title_short Impact of Mental Illnesses Treatment During the Period 1950-2020: Analysis of A Single Mental Institution, Buenos Aires, Argentina
title_full Impact of Mental Illnesses Treatment During the Period 1950-2020: Analysis of A Single Mental Institution, Buenos Aires, Argentina
title_fullStr Impact of Mental Illnesses Treatment During the Period 1950-2020: Analysis of A Single Mental Institution, Buenos Aires, Argentina
title_full_unstemmed Impact of Mental Illnesses Treatment During the Period 1950-2020: Analysis of A Single Mental Institution, Buenos Aires, Argentina
title_sort Impact of Mental Illnesses Treatment During the Period 1950-2020: Analysis of A Single Mental Institution, Buenos Aires, Argentina
dc.creator.none.fl_str_mv Marín, Gustavo H.
Giangreco, Lucia
Valdez, Emilia
Heig, Melina
Kersich, Blas
Marin, Gina
Marín, Lupe
author Marín, Gustavo H.
author_facet Marín, Gustavo H.
Giangreco, Lucia
Valdez, Emilia
Heig, Melina
Kersich, Blas
Marin, Gina
Marín, Lupe
author_role author
author2 Giangreco, Lucia
Valdez, Emilia
Heig, Melina
Kersich, Blas
Marin, Gina
Marín, Lupe
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Psiquiatría
Mental
Health
Treatment
Drugs
Hospitalization
topic Psiquiatría
Mental
Health
Treatment
Drugs
Hospitalization
dc.description.none.fl_txt_mv Introduction: Mental health treatment has varied in the last century; however, the impact of these new therapeutical options is little-known. Objectives: To evaluate the impact of treatments for mental health diseases along the last decades. Methodology: retrospective, descriptive case-report study. Medical records of patients admitted to a Mental Health Institution in Buenos Aires, Argentina were evaluated over 7 decades. Variables analyzed were: age, sex, diagnosis, time of hospital stay, number of re-hospitalizations, drugs available per decade, cost of drug, cost of hospitalizations. Results: Hospitalization stay was 6.33 months, with 3.18 readmissions per patient (in the 21st century it was detected a reduction in the length of hospitalization (4.66 months) and an increase in the number of hospitalizations (4.3 hospitalizations/patient). The numer of drugs prescribed was 5.14 per patient (1.6 in the 1950s and 7.22 in the last decade). During 1950s, the most prescribed drugs were lithium and chlorpromazine, in the ’60s haloperidol; in the ‘70s benzodiazepines, haloperidol, and amitriptyline; in the ‘80s and ‘90s fluoxetine, sertraline, and BZD; from the 2000s paroxetine, risperidone, and pregabalin were added to the earlier drugs; and in the current decade new antipsychotics (olanzapine, ziprasidone, quetiapine or lurasidone), antiepileptics (lamotrigine) were included. Although diagnoses were maintained over time (schizophrenia, psychosis, bipolar disorder, dementia, depression) in the last decade, 27.7% of the hospitalized patients had dual pathology (addiction+other mental illness). Cost of drugs prescribed increased >9 times, while cost of hospitalization increased >4 times in the last decade compared to the second half of the 20th century. Conclusion: Although new drugs to treat severe mental disorders reduced side effects associate to treatment, its efficacy did not improve neither the duration of the hospital stay nor in the number of re-hospitalizations along the past 70 years; while cost of new drugs increased 9 times.
description Introduction: Mental health treatment has varied in the last century; however, the impact of these new therapeutical options is little-known. Objectives: To evaluate the impact of treatments for mental health diseases along the last decades. Methodology: retrospective, descriptive case-report study. Medical records of patients admitted to a Mental Health Institution in Buenos Aires, Argentina were evaluated over 7 decades. Variables analyzed were: age, sex, diagnosis, time of hospital stay, number of re-hospitalizations, drugs available per decade, cost of drug, cost of hospitalizations. Results: Hospitalization stay was 6.33 months, with 3.18 readmissions per patient (in the 21st century it was detected a reduction in the length of hospitalization (4.66 months) and an increase in the number of hospitalizations (4.3 hospitalizations/patient). The numer of drugs prescribed was 5.14 per patient (1.6 in the 1950s and 7.22 in the last decade). During 1950s, the most prescribed drugs were lithium and chlorpromazine, in the ’60s haloperidol; in the ‘70s benzodiazepines, haloperidol, and amitriptyline; in the ‘80s and ‘90s fluoxetine, sertraline, and BZD; from the 2000s paroxetine, risperidone, and pregabalin were added to the earlier drugs; and in the current decade new antipsychotics (olanzapine, ziprasidone, quetiapine or lurasidone), antiepileptics (lamotrigine) were included. Although diagnoses were maintained over time (schizophrenia, psychosis, bipolar disorder, dementia, depression) in the last decade, 27.7% of the hospitalized patients had dual pathology (addiction+other mental illness). Cost of drugs prescribed increased >9 times, while cost of hospitalization increased >4 times in the last decade compared to the second half of the 20th century. Conclusion: Although new drugs to treat severe mental disorders reduced side effects associate to treatment, its efficacy did not improve neither the duration of the hospital stay nor in the number of re-hospitalizations along the past 70 years; while cost of new drugs increased 9 times.
publishDate 2020
dc.date.none.fl_str_mv 2020
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