Impact of mental illnesses treatment during the period 1950-2020: Analysis of a single mental institution, Buenos Aires, Argentina

Autores
Marin, Gustavo Horacio; Giangreco, Lucia; Marin, Lupe; Valdez, Emilia; Heig, Melina; Kersich, Blas; Marin, Gina
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Introduction: Mental health treatment has varied in the last century; however, the impact of these new therapeutical options is little-known. Objectives: To evaluate the impact of treatments for mental health diseases along the last decades. Methodology: retrospective, descriptive case-report study. Medical records of patients admitted to a Mental Health Institution in Buenos Aires, Argentina were evaluated over 7 decades. Variables analyzed were: age, sex, diagnosis, time of hospital stay, number of re-hospitalizations, drugs available per decade, cost of drug, cost of hospitalizations. Results: Hospitalization average lenght of stay was 6.33 months, with 3.18 readmissions per patient. In the 21st century it was detected a reduction in the length of hospitalization (4.66 months) and an increase in the number of hospitalizations (4.3 hospitalizations/patient). The number of drugs prescribed was 5.14 per patient (1.6 in the 1950s and 7.22 in the last decade). During 1950s, the most prescribed drugs were lithium and chlorpromazine, in the ’60s haloperidol; in the ‘70s benzodiazepines, haloperidol, and amitriptyline; in the ‘80s and ‘90s fluoxetine, sertraline, and BZD; from the 2000s paroxetine, risperidone, and pregabalin were added to the earlier drugs; and in the current decade new antipsychotics (olanzapine, ziprasidone, quetiapine or lurasidone), antiepileptics (lamotrigine) were included. Although diagnoses were maintained over time (schizophrenia, psychosis, bipolar disorder, dementia, depression) in the last decade, 27.7% of the hospitalized patients had dual pathology (addiction+other mental illness). Cost of drugs prescribed increased >9 times, while the cost of hospitalization increased >4 times in the last decade compared to the second half of the 20th century. Conclusion: Although new drugs to treat severe mental disorders reduced side effects associate to treatment, its efficacy did not improve neither the duration of the hospital stay nor in the number of re-hospitalizations along the past 70 years; while cost of new drugs increased 9 times.
Fil: Marin, Gustavo Horacio. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Departamento de Articulación de Ciencias Básicas y Clínicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Fil: Giangreco, Lucia. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina
Fil: Marin, Lupe. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina
Fil: Valdez, Emilia. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina
Fil: Heig, Melina. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina
Fil: Kersich, Blas. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina
Fil: Marin, Gina. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina
Materia
Mental
Health
Treatment
Drugs
Hospitalization
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/150334
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/150334
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Impact of mental illnesses treatment during the period 1950-2020: Analysis of a single mental institution, Buenos Aires, ArgentinaMarin, Gustavo HoracioGiangreco, LuciaMarin, LupeValdez, EmiliaHeig, MelinaKersich, BlasMarin, GinaMentalHealthTreatmentDrugsHospitalizationhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Introduction: Mental health treatment has varied in the last century; however, the impact of these new therapeutical options is little-known. Objectives: To evaluate the impact of treatments for mental health diseases along the last decades. Methodology: retrospective, descriptive case-report study. Medical records of patients admitted to a Mental Health Institution in Buenos Aires, Argentina were evaluated over 7 decades. Variables analyzed were: age, sex, diagnosis, time of hospital stay, number of re-hospitalizations, drugs available per decade, cost of drug, cost of hospitalizations. Results: Hospitalization average lenght of stay was 6.33 months, with 3.18 readmissions per patient. In the 21st century it was detected a reduction in the length of hospitalization (4.66 months) and an increase in the number of hospitalizations (4.3 hospitalizations/patient). The number of drugs prescribed was 5.14 per patient (1.6 in the 1950s and 7.22 in the last decade). During 1950s, the most prescribed drugs were lithium and chlorpromazine, in the ’60s haloperidol; in the ‘70s benzodiazepines, haloperidol, and amitriptyline; in the ‘80s and ‘90s fluoxetine, sertraline, and BZD; from the 2000s paroxetine, risperidone, and pregabalin were added to the earlier drugs; and in the current decade new antipsychotics (olanzapine, ziprasidone, quetiapine or lurasidone), antiepileptics (lamotrigine) were included. Although diagnoses were maintained over time (schizophrenia, psychosis, bipolar disorder, dementia, depression) in the last decade, 27.7% of the hospitalized patients had dual pathology (addiction+other mental illness). Cost of drugs prescribed increased >9 times, while the cost of hospitalization increased >4 times in the last decade compared to the second half of the 20th century. Conclusion: Although new drugs to treat severe mental disorders reduced side effects associate to treatment, its efficacy did not improve neither the duration of the hospital stay nor in the number of re-hospitalizations along the past 70 years; while cost of new drugs increased 9 times.Fil: Marin, Gustavo Horacio. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Departamento de Articulación de Ciencias Básicas y Clínicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Giangreco, Lucia. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; ArgentinaFil: Marin, Lupe. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; ArgentinaFil: Valdez, Emilia. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; ArgentinaFil: Heig, Melina. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; ArgentinaFil: Kersich, Blas. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; ArgentinaFil: Marin, Gina. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; ArgentinaSciVision Publishers LLC2020-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/150334Marin, Gustavo Horacio; Giangreco, Lucia; Marin, Lupe; Valdez, Emilia; Heig, Melina; et al.; Impact of mental illnesses treatment during the period 1950-2020: Analysis of a single mental institution, Buenos Aires, Argentina; SciVision Publishers LLC; International Journal of Psychiatry Research; 3; 6; 12-2020; 1-52641-4317CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.33425/2641-4317.1077info:eu-repo/semantics/altIdentifier/url/https://www.scivisionpub.com/abstract-display.php?id=1353info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:48:10Zoai:ri.conicet.gov.ar:11336/150334instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:48:10.726CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Impact of mental illnesses treatment during the period 1950-2020: Analysis of a single mental institution, Buenos Aires, Argentina
title Impact of mental illnesses treatment during the period 1950-2020: Analysis of a single mental institution, Buenos Aires, Argentina
spellingShingle Impact of mental illnesses treatment during the period 1950-2020: Analysis of a single mental institution, Buenos Aires, Argentina
Marin, Gustavo Horacio
Mental
Health
Treatment
Drugs
Hospitalization
title_short Impact of mental illnesses treatment during the period 1950-2020: Analysis of a single mental institution, Buenos Aires, Argentina
title_full Impact of mental illnesses treatment during the period 1950-2020: Analysis of a single mental institution, Buenos Aires, Argentina
title_fullStr Impact of mental illnesses treatment during the period 1950-2020: Analysis of a single mental institution, Buenos Aires, Argentina
title_full_unstemmed Impact of mental illnesses treatment during the period 1950-2020: Analysis of a single mental institution, Buenos Aires, Argentina
title_sort Impact of mental illnesses treatment during the period 1950-2020: Analysis of a single mental institution, Buenos Aires, Argentina
dc.creator.none.fl_str_mv Marin, Gustavo Horacio
Giangreco, Lucia
Marin, Lupe
Valdez, Emilia
Heig, Melina
Kersich, Blas
Marin, Gina
author Marin, Gustavo Horacio
author_facet Marin, Gustavo Horacio
Giangreco, Lucia
Marin, Lupe
Valdez, Emilia
Heig, Melina
Kersich, Blas
Marin, Gina
author_role author
author2 Giangreco, Lucia
Marin, Lupe
Valdez, Emilia
Heig, Melina
Kersich, Blas
Marin, Gina
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Mental
Health
Treatment
Drugs
Hospitalization
topic Mental
Health
Treatment
Drugs
Hospitalization
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Introduction: Mental health treatment has varied in the last century; however, the impact of these new therapeutical options is little-known. Objectives: To evaluate the impact of treatments for mental health diseases along the last decades. Methodology: retrospective, descriptive case-report study. Medical records of patients admitted to a Mental Health Institution in Buenos Aires, Argentina were evaluated over 7 decades. Variables analyzed were: age, sex, diagnosis, time of hospital stay, number of re-hospitalizations, drugs available per decade, cost of drug, cost of hospitalizations. Results: Hospitalization average lenght of stay was 6.33 months, with 3.18 readmissions per patient. In the 21st century it was detected a reduction in the length of hospitalization (4.66 months) and an increase in the number of hospitalizations (4.3 hospitalizations/patient). The number of drugs prescribed was 5.14 per patient (1.6 in the 1950s and 7.22 in the last decade). During 1950s, the most prescribed drugs were lithium and chlorpromazine, in the ’60s haloperidol; in the ‘70s benzodiazepines, haloperidol, and amitriptyline; in the ‘80s and ‘90s fluoxetine, sertraline, and BZD; from the 2000s paroxetine, risperidone, and pregabalin were added to the earlier drugs; and in the current decade new antipsychotics (olanzapine, ziprasidone, quetiapine or lurasidone), antiepileptics (lamotrigine) were included. Although diagnoses were maintained over time (schizophrenia, psychosis, bipolar disorder, dementia, depression) in the last decade, 27.7% of the hospitalized patients had dual pathology (addiction+other mental illness). Cost of drugs prescribed increased >9 times, while the cost of hospitalization increased >4 times in the last decade compared to the second half of the 20th century. Conclusion: Although new drugs to treat severe mental disorders reduced side effects associate to treatment, its efficacy did not improve neither the duration of the hospital stay nor in the number of re-hospitalizations along the past 70 years; while cost of new drugs increased 9 times.
Fil: Marin, Gustavo Horacio. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Departamento de Articulación de Ciencias Básicas y Clínicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Fil: Giangreco, Lucia. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina
Fil: Marin, Lupe. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina
Fil: Valdez, Emilia. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina
Fil: Heig, Melina. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina
Fil: Kersich, Blas. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina
Fil: Marin, Gina. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina
description Introduction: Mental health treatment has varied in the last century; however, the impact of these new therapeutical options is little-known. Objectives: To evaluate the impact of treatments for mental health diseases along the last decades. Methodology: retrospective, descriptive case-report study. Medical records of patients admitted to a Mental Health Institution in Buenos Aires, Argentina were evaluated over 7 decades. Variables analyzed were: age, sex, diagnosis, time of hospital stay, number of re-hospitalizations, drugs available per decade, cost of drug, cost of hospitalizations. Results: Hospitalization average lenght of stay was 6.33 months, with 3.18 readmissions per patient. In the 21st century it was detected a reduction in the length of hospitalization (4.66 months) and an increase in the number of hospitalizations (4.3 hospitalizations/patient). The number of drugs prescribed was 5.14 per patient (1.6 in the 1950s and 7.22 in the last decade). During 1950s, the most prescribed drugs were lithium and chlorpromazine, in the ’60s haloperidol; in the ‘70s benzodiazepines, haloperidol, and amitriptyline; in the ‘80s and ‘90s fluoxetine, sertraline, and BZD; from the 2000s paroxetine, risperidone, and pregabalin were added to the earlier drugs; and in the current decade new antipsychotics (olanzapine, ziprasidone, quetiapine or lurasidone), antiepileptics (lamotrigine) were included. Although diagnoses were maintained over time (schizophrenia, psychosis, bipolar disorder, dementia, depression) in the last decade, 27.7% of the hospitalized patients had dual pathology (addiction+other mental illness). Cost of drugs prescribed increased >9 times, while the cost of hospitalization increased >4 times in the last decade compared to the second half of the 20th century. Conclusion: Although new drugs to treat severe mental disorders reduced side effects associate to treatment, its efficacy did not improve neither the duration of the hospital stay nor in the number of re-hospitalizations along the past 70 years; while cost of new drugs increased 9 times.
publishDate 2020
dc.date.none.fl_str_mv 2020-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/150334
Marin, Gustavo Horacio; Giangreco, Lucia; Marin, Lupe; Valdez, Emilia; Heig, Melina; et al.; Impact of mental illnesses treatment during the period 1950-2020: Analysis of a single mental institution, Buenos Aires, Argentina; SciVision Publishers LLC; International Journal of Psychiatry Research; 3; 6; 12-2020; 1-5
2641-4317
CONICET Digital
CONICET
url http://hdl.handle.net/11336/150334
identifier_str_mv Marin, Gustavo Horacio; Giangreco, Lucia; Marin, Lupe; Valdez, Emilia; Heig, Melina; et al.; Impact of mental illnesses treatment during the period 1950-2020: Analysis of a single mental institution, Buenos Aires, Argentina; SciVision Publishers LLC; International Journal of Psychiatry Research; 3; 6; 12-2020; 1-5
2641-4317
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.33425/2641-4317.1077
info:eu-repo/semantics/altIdentifier/url/https://www.scivisionpub.com/abstract-display.php?id=1353
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv SciVision Publishers LLC
publisher.none.fl_str_mv SciVision Publishers LLC
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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