Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome Markers

Autores
Di Santo Meztler, Gabriela Paula; del Palacio, Santiago; Esteban, María E.; Armoa, Isaías; Argüelles, Carina Francisca; Catanesi, Cecilia Inés
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Alu insertions, INDELs, and SNPs in the X chromosome can be useful not only for revealing relationships among populations but also for identification purposes. We present data of 10 Alu insertions, 5 INDELs, and 15 SNPs of X-chromosome from three Argentinian north-east cities in order to gain insight into the genetic diversity of the X chromosome within this region of the country. Data from 198 unrelated individuals belonging to Posadas, Corrientes, and Eldorado cities were genotyped for Ya5DP62, Yb8DP49, Ya5DP3, Ya5NBC37, Ya5DP77, Ya5NBC491, Ya5DP4, Ya5DP13, Yb8NBC634, and Yb8NBC102 Alu insertions, for MID193, MID1705, MID3754, MID3756 and MID1540 Indels and for rs6639398, rs5986751, rs5964206, rs9781645, rs2209420, rs1299087, rs318173, rs933315, rs1991961, rs4825889, rs1781116, rs1937193, rs1781104, rs149910, and rs652 SNPs. No deviations fromHardy-Weinberg equilibrium were observed for Posadas and Corrientes. However, Eldorado showed significant values, and it was found to have an internal substructuring with two groups of different origin, one showing higher similarity with European countries, and the other with more similarities to Posadas and Corrientes. Fst pairwise genetic distances emerged for some markers among the studied populations and also between our data and those from other countries and continents. Of particular interest, Alu insertions demonstrated the most differences, and could be of use in ancestry studies for these populations, while INDELs and SNPs variation were informative for differentiation within the country.
Materia
Biología Celular, Microbiología
Genética Humana
polymorphism, X chromosome, genetic variation, Alus, INDELs, SNPs, Argentina
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-nd/4.0/
Repositorio
CIC Digital (CICBA)
Institución
Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
OAI Identificador
oai:digital.cic.gba.gob.ar:11746/8271

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oai_identifier_str oai:digital.cic.gba.gob.ar:11746/8271
network_acronym_str CICBA
repository_id_str 9441
network_name_str CIC Digital (CICBA)
spelling Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome MarkersDi Santo Meztler, Gabriela Pauladel Palacio, SantiagoEsteban, María E.Armoa, IsaíasArgüelles, Carina FranciscaCatanesi, Cecilia InésBiología Celular, MicrobiologíaGenética Humanapolymorphism, X chromosome, genetic variation, Alus, INDELs, SNPs, ArgentinaAlu insertions, INDELs, and SNPs in the X chromosome can be useful not only for revealing relationships among populations but also for identification purposes. We present data of 10 Alu insertions, 5 INDELs, and 15 SNPs of X-chromosome from three Argentinian north-east cities in order to gain insight into the genetic diversity of the X chromosome within this region of the country. Data from 198 unrelated individuals belonging to Posadas, Corrientes, and Eldorado cities were genotyped for Ya5DP62, Yb8DP49, Ya5DP3, Ya5NBC37, Ya5DP77, Ya5NBC491, Ya5DP4, Ya5DP13, Yb8NBC634, and Yb8NBC102 Alu insertions, for MID193, MID1705, MID3754, MID3756 and MID1540 Indels and for rs6639398, rs5986751, rs5964206, rs9781645, rs2209420, rs1299087, rs318173, rs933315, rs1991961, rs4825889, rs1781116, rs1937193, rs1781104, rs149910, and rs652 SNPs. No deviations fromHardy-Weinberg equilibrium were observed for Posadas and Corrientes. However, Eldorado showed significant values, and it was found to have an internal substructuring with two groups of different origin, one showing higher similarity with European countries, and the other with more similarities to Posadas and Corrientes. Fst pairwise genetic distances emerged for some markers among the studied populations and also between our data and those from other countries and continents. Of particular interest, Alu insertions demonstrated the most differences, and could be of use in ancestry studies for these populations, while INDELs and SNPs variation were informative for differentiation within the country.2018info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://digital.cic.gba.gob.ar/handle/11746/8271enghttp://sedici.unlp.edu.ar/handle/10915/66905info:eu-repo/semantics/altIdentifier/doi/10.3389/fgene.2018.00208Argentinainfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/4.0/reponame:CIC Digital (CICBA)instname:Comisión de Investigaciones Científicas de la Provincia de Buenos Airesinstacron:CICBA2025-09-29T13:40:02Zoai:digital.cic.gba.gob.ar:11746/8271Institucionalhttp://digital.cic.gba.gob.arOrganismo científico-tecnológicoNo correspondehttp://digital.cic.gba.gob.ar/oai/snrdmarisa.degiusti@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:94412025-09-29 13:40:03.062CIC Digital (CICBA) - Comisión de Investigaciones Científicas de la Provincia de Buenos Airesfalse
dc.title.none.fl_str_mv Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome Markers
title Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome Markers
spellingShingle Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome Markers
Di Santo Meztler, Gabriela Paula
Biología Celular, Microbiología
Genética Humana
polymorphism, X chromosome, genetic variation, Alus, INDELs, SNPs, Argentina
title_short Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome Markers
title_full Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome Markers
title_fullStr Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome Markers
title_full_unstemmed Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome Markers
title_sort Genetic Differentiation of North-East Argentina Populations Based on 30 Binary X Chromosome Markers
dc.creator.none.fl_str_mv Di Santo Meztler, Gabriela Paula
del Palacio, Santiago
Esteban, María E.
Armoa, Isaías
Argüelles, Carina Francisca
Catanesi, Cecilia Inés
author Di Santo Meztler, Gabriela Paula
author_facet Di Santo Meztler, Gabriela Paula
del Palacio, Santiago
Esteban, María E.
Armoa, Isaías
Argüelles, Carina Francisca
Catanesi, Cecilia Inés
author_role author
author2 del Palacio, Santiago
Esteban, María E.
Armoa, Isaías
Argüelles, Carina Francisca
Catanesi, Cecilia Inés
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Biología Celular, Microbiología
Genética Humana
polymorphism, X chromosome, genetic variation, Alus, INDELs, SNPs, Argentina
topic Biología Celular, Microbiología
Genética Humana
polymorphism, X chromosome, genetic variation, Alus, INDELs, SNPs, Argentina
dc.description.none.fl_txt_mv Alu insertions, INDELs, and SNPs in the X chromosome can be useful not only for revealing relationships among populations but also for identification purposes. We present data of 10 Alu insertions, 5 INDELs, and 15 SNPs of X-chromosome from three Argentinian north-east cities in order to gain insight into the genetic diversity of the X chromosome within this region of the country. Data from 198 unrelated individuals belonging to Posadas, Corrientes, and Eldorado cities were genotyped for Ya5DP62, Yb8DP49, Ya5DP3, Ya5NBC37, Ya5DP77, Ya5NBC491, Ya5DP4, Ya5DP13, Yb8NBC634, and Yb8NBC102 Alu insertions, for MID193, MID1705, MID3754, MID3756 and MID1540 Indels and for rs6639398, rs5986751, rs5964206, rs9781645, rs2209420, rs1299087, rs318173, rs933315, rs1991961, rs4825889, rs1781116, rs1937193, rs1781104, rs149910, and rs652 SNPs. No deviations fromHardy-Weinberg equilibrium were observed for Posadas and Corrientes. However, Eldorado showed significant values, and it was found to have an internal substructuring with two groups of different origin, one showing higher similarity with European countries, and the other with more similarities to Posadas and Corrientes. Fst pairwise genetic distances emerged for some markers among the studied populations and also between our data and those from other countries and continents. Of particular interest, Alu insertions demonstrated the most differences, and could be of use in ancestry studies for these populations, while INDELs and SNPs variation were informative for differentiation within the country.
description Alu insertions, INDELs, and SNPs in the X chromosome can be useful not only for revealing relationships among populations but also for identification purposes. We present data of 10 Alu insertions, 5 INDELs, and 15 SNPs of X-chromosome from three Argentinian north-east cities in order to gain insight into the genetic diversity of the X chromosome within this region of the country. Data from 198 unrelated individuals belonging to Posadas, Corrientes, and Eldorado cities were genotyped for Ya5DP62, Yb8DP49, Ya5DP3, Ya5NBC37, Ya5DP77, Ya5NBC491, Ya5DP4, Ya5DP13, Yb8NBC634, and Yb8NBC102 Alu insertions, for MID193, MID1705, MID3754, MID3756 and MID1540 Indels and for rs6639398, rs5986751, rs5964206, rs9781645, rs2209420, rs1299087, rs318173, rs933315, rs1991961, rs4825889, rs1781116, rs1937193, rs1781104, rs149910, and rs652 SNPs. No deviations fromHardy-Weinberg equilibrium were observed for Posadas and Corrientes. However, Eldorado showed significant values, and it was found to have an internal substructuring with two groups of different origin, one showing higher similarity with European countries, and the other with more similarities to Posadas and Corrientes. Fst pairwise genetic distances emerged for some markers among the studied populations and also between our data and those from other countries and continents. Of particular interest, Alu insertions demonstrated the most differences, and could be of use in ancestry studies for these populations, while INDELs and SNPs variation were informative for differentiation within the country.
publishDate 2018
dc.date.none.fl_str_mv 2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://digital.cic.gba.gob.ar/handle/11746/8271
url https://digital.cic.gba.gob.ar/handle/11746/8271
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/66905
info:eu-repo/semantics/altIdentifier/doi/10.3389/fgene.2018.00208
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http://creativecommons.org/licenses/by-nc-nd/4.0/
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dc.source.none.fl_str_mv reponame:CIC Digital (CICBA)
instname:Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
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reponame_str CIC Digital (CICBA)
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instname_str Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
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repository.name.fl_str_mv CIC Digital (CICBA) - Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
repository.mail.fl_str_mv marisa.degiusti@sedici.unlp.edu.ar
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