Evaluation of the in vitro activity of amphotericin B by time-kill curve methodology against large and small capsulate C. neoformans isolates

Autores
Córdoba, Susana; Afeltra, Javier; Vitale, Roxana G
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Fil: Córdoba, Susana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Micologia; Argentina.
Fil: Afeltra, Javier. Hospital Dr. José María Ramos Mejía. Micologia. Unidad de Parasitologia; Argentina.
Fil: Vitale, Roxana G. Hospital Dr. José María Ramos Mejía. Micologia. Unidad de Parasitologia; Argentina.
We have evaluated and compared the activity of amphotericin B (AMB) by time-kill curve methodology against 20 clinical Cryptococcus neoformans isolates in which capsule induction in vitro was performed. Overall, large capsulated isolates were more resistant to killing by AMB over time when compared with those small capsulate ones.
Fuente
Diagnostic Microbiology and Infectious Disease 2011; 71(3):260-2
Materia
Anfotericina B
Antifúngicos
Cryptococcus neoformans
Humanos
Factores de Tiempo
Pruebas de Sensibilidad Microbiana
Nivel de accesibilidad
acceso abierto
Condiciones de uso
none
Repositorio
Sistema de Gestión del Conocimiento ANLIS MALBRÁN
Institución
Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
OAI Identificador
oai:sgc.anlis.gob.ar:Publications/123456789/1896
Acceder
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network_acronym_str SGCANLIS
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network_name_str Sistema de Gestión del Conocimiento ANLIS MALBRÁN
spelling Evaluation of the in vitro activity of amphotericin B by time-kill curve methodology against large and small capsulate C. neoformans isolatesCórdoba, SusanaAfeltra, JavierVitale, Roxana GAnfotericina BAntifúngicosCryptococcus neoformansHumanosFactores de TiempoPruebas de Sensibilidad MicrobianaFil: Córdoba, Susana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Micologia; Argentina.Fil: Afeltra, Javier. Hospital Dr. José María Ramos Mejía. Micologia. Unidad de Parasitologia; Argentina.Fil: Vitale, Roxana G. Hospital Dr. José María Ramos Mejía. Micologia. Unidad de Parasitologia; Argentina.We have evaluated and compared the activity of amphotericin B (AMB) by time-kill curve methodology against 20 clinical Cryptococcus neoformans isolates in which capsule induction in vitro was performed. Overall, large capsulated isolates were more resistant to killing by AMB over time when compared with those small capsulate ones.Elsevier2011-11info:ar-repo/semantics/articuloinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://sgc.anlis.gob.ar/handle/123456789/189610.1016/j.diagmicrobio.2011.08.003Diagnostic Microbiology and Infectious Disease 2011; 71(3):260-2reponame:Sistema de Gestión del Conocimiento ANLIS MALBRÁNinstname:Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"instacron:ANLIS#PLACEHOLDER_PARENT_METADATA_VALUE#datasetsDiagnostic microbiology and infectious diseasenoneinfo:eu-repo/semantics/openAccesseng2025-09-29T14:30:30Zoai:sgc.anlis.gob.ar:Publications/123456789/1896Institucionalhttp://sgc.anlis.gob.ar/Organismo científico-tecnológicoNo correspondehttp://sgc.anlis.gob.ar/oai/biblioteca@anlis.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:a2025-09-29 14:30:31.049Sistema de Gestión del Conocimiento ANLIS MALBRÁN - Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"false
dc.title.none.fl_str_mv Evaluation of the in vitro activity of amphotericin B by time-kill curve methodology against large and small capsulate C. neoformans isolates
title Evaluation of the in vitro activity of amphotericin B by time-kill curve methodology against large and small capsulate C. neoformans isolates
spellingShingle Evaluation of the in vitro activity of amphotericin B by time-kill curve methodology against large and small capsulate C. neoformans isolates
Córdoba, Susana
Anfotericina B
Antifúngicos
Cryptococcus neoformans
Humanos
Factores de Tiempo
Pruebas de Sensibilidad Microbiana
title_short Evaluation of the in vitro activity of amphotericin B by time-kill curve methodology against large and small capsulate C. neoformans isolates
title_full Evaluation of the in vitro activity of amphotericin B by time-kill curve methodology against large and small capsulate C. neoformans isolates
title_fullStr Evaluation of the in vitro activity of amphotericin B by time-kill curve methodology against large and small capsulate C. neoformans isolates
title_full_unstemmed Evaluation of the in vitro activity of amphotericin B by time-kill curve methodology against large and small capsulate C. neoformans isolates
title_sort Evaluation of the in vitro activity of amphotericin B by time-kill curve methodology against large and small capsulate C. neoformans isolates
dc.creator.none.fl_str_mv Córdoba, Susana
Afeltra, Javier
Vitale, Roxana G
author Córdoba, Susana
author_facet Córdoba, Susana
Afeltra, Javier
Vitale, Roxana G
author_role author
author2 Afeltra, Javier
Vitale, Roxana G
author2_role author
author
dc.subject.none.fl_str_mv Anfotericina B
Antifúngicos
Cryptococcus neoformans
Humanos
Factores de Tiempo
Pruebas de Sensibilidad Microbiana
topic Anfotericina B
Antifúngicos
Cryptococcus neoformans
Humanos
Factores de Tiempo
Pruebas de Sensibilidad Microbiana
dc.description.none.fl_txt_mv Fil: Córdoba, Susana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Micologia; Argentina.
Fil: Afeltra, Javier. Hospital Dr. José María Ramos Mejía. Micologia. Unidad de Parasitologia; Argentina.
Fil: Vitale, Roxana G. Hospital Dr. José María Ramos Mejía. Micologia. Unidad de Parasitologia; Argentina.
We have evaluated and compared the activity of amphotericin B (AMB) by time-kill curve methodology against 20 clinical Cryptococcus neoformans isolates in which capsule induction in vitro was performed. Overall, large capsulated isolates were more resistant to killing by AMB over time when compared with those small capsulate ones.
description Fil: Córdoba, Susana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Micologia; Argentina.
publishDate 2011
dc.date.none.fl_str_mv 2011-11
dc.type.none.fl_str_mv info:ar-repo/semantics/articulo
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sgc.anlis.gob.ar/handle/123456789/1896
10.1016/j.diagmicrobio.2011.08.003
url http://sgc.anlis.gob.ar/handle/123456789/1896
identifier_str_mv 10.1016/j.diagmicrobio.2011.08.003
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
datasets
Diagnostic microbiology and infectious disease
dc.rights.none.fl_str_mv none
info:eu-repo/semantics/openAccess
rights_invalid_str_mv none
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv Diagnostic Microbiology and Infectious Disease 2011; 71(3):260-2
reponame:Sistema de Gestión del Conocimiento ANLIS MALBRÁN
instname:Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
instacron:ANLIS
reponame_str Sistema de Gestión del Conocimiento ANLIS MALBRÁN
collection Sistema de Gestión del Conocimiento ANLIS MALBRÁN
instname_str Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
instacron_str ANLIS
institution ANLIS
repository.name.fl_str_mv Sistema de Gestión del Conocimiento ANLIS MALBRÁN - Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
repository.mail.fl_str_mv biblioteca@anlis.gov.ar
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score 12.559606

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