Therapy of chagas disease : implications for levels of prevention

Autores
Sosa-Estani, Sergio; Colantonio, Lisandro; Segura, Elsa L.
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Fil: Sosa-Estani, Sergio. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina.
Fil: Colantonio, Lisandro. Universidad de Buenos Aires. Departamento de Salud Pública; Argentina.
Fil: Segura, Elsa Leonor. ANLIS Dr.C.G.Malbrán. Centro Nacional de Diagnóstico e Investigación en Endemo-Epidemias; Argentina.
This paper reviews the evidence supporting the use of etiological treatment for Chagas disease that has changed the standard of care for patients with Trypanosoma cruzi infection in the last decades. Implications of this evidence on different levels of prevention as well as gaps in current knowledge are also discussed. In this regard, etiological treatment has shown to be beneficial as an intervention for secondary prevention to successfully cure the infection or to delay, reduce, or prevent the progression to disease, and as primary disease prevention by breaking the chain of transmission. Timely diagnosis during initial stages would allow for the prescription of appropriate therapies mainly in the primary health care system thus improving chances for a better quality of life. Based on current evidence, etiological treatment has to be considered as an essential public health strategy useful to reduce disease burden and to eliminate Chagas disease altogether.
Fuente
Journal of Tropical Medicine 2012; 2012:1-10.
Materia
Enfermedad de Chagas
Trypanosoma cruzi
Nivel de accesibilidad
acceso abierto
Condiciones de uso
Repositorio
Sistema de Gestión del Conocimiento ANLIS MALBRÁN
Institución
Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
OAI Identificador
oai:sgc.anlis.gob.ar:123456789/429

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spelling Therapy of chagas disease : implications for levels of preventionSosa-Estani, SergioColantonio, LisandroSegura, Elsa L.Enfermedad de ChagasTrypanosoma cruziFil: Sosa-Estani, Sergio. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina.Fil: Colantonio, Lisandro. Universidad de Buenos Aires. Departamento de Salud Pública; Argentina.Fil: Segura, Elsa Leonor. ANLIS Dr.C.G.Malbrán. Centro Nacional de Diagnóstico e Investigación en Endemo-Epidemias; Argentina.This paper reviews the evidence supporting the use of etiological treatment for Chagas disease that has changed the standard of care for patients with Trypanosoma cruzi infection in the last decades. Implications of this evidence on different levels of prevention as well as gaps in current knowledge are also discussed. In this regard, etiological treatment has shown to be beneficial as an intervention for secondary prevention to successfully cure the infection or to delay, reduce, or prevent the progression to disease, and as primary disease prevention by breaking the chain of transmission. Timely diagnosis during initial stages would allow for the prescription of appropriate therapies mainly in the primary health care system thus improving chances for a better quality of life. Based on current evidence, etiological treatment has to be considered as an essential public health strategy useful to reduce disease burden and to eliminate Chagas disease altogether.Hindawi2012info:ar-repo/semantics/articuloinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdf1687-9686http://sgc.anlis.gob.ar/handle/123456789/429http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317183/pdf/JTM2012-292138.pdfJournal of Tropical Medicine 2012; 2012:1-10.reponame:Sistema de Gestión del Conocimiento ANLIS MALBRÁNinstname:Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"instacron:ANLISJournal of tropical medicineenginfo:eu-repo/semantics/openAccess2025-09-04T11:15:51Zoai:sgc.anlis.gob.ar:123456789/429Institucionalhttp://sgc.anlis.gob.ar/Organismo científico-tecnológicoNo correspondehttp://sgc.anlis.gob.ar/oai/biblioteca@anlis.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:a2025-09-04 11:15:51.513Sistema de Gestión del Conocimiento ANLIS MALBRÁN - Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"false
dc.title.none.fl_str_mv Therapy of chagas disease : implications for levels of prevention
title Therapy of chagas disease : implications for levels of prevention
spellingShingle Therapy of chagas disease : implications for levels of prevention
Sosa-Estani, Sergio
Enfermedad de Chagas
Trypanosoma cruzi
title_short Therapy of chagas disease : implications for levels of prevention
title_full Therapy of chagas disease : implications for levels of prevention
title_fullStr Therapy of chagas disease : implications for levels of prevention
title_full_unstemmed Therapy of chagas disease : implications for levels of prevention
title_sort Therapy of chagas disease : implications for levels of prevention
dc.creator.none.fl_str_mv Sosa-Estani, Sergio
Colantonio, Lisandro
Segura, Elsa L.
author Sosa-Estani, Sergio
author_facet Sosa-Estani, Sergio
Colantonio, Lisandro
Segura, Elsa L.
author_role author
author2 Colantonio, Lisandro
Segura, Elsa L.
author2_role author
author
dc.subject.none.fl_str_mv Enfermedad de Chagas
Trypanosoma cruzi
topic Enfermedad de Chagas
Trypanosoma cruzi
dc.description.none.fl_txt_mv Fil: Sosa-Estani, Sergio. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina.
Fil: Colantonio, Lisandro. Universidad de Buenos Aires. Departamento de Salud Pública; Argentina.
Fil: Segura, Elsa Leonor. ANLIS Dr.C.G.Malbrán. Centro Nacional de Diagnóstico e Investigación en Endemo-Epidemias; Argentina.
This paper reviews the evidence supporting the use of etiological treatment for Chagas disease that has changed the standard of care for patients with Trypanosoma cruzi infection in the last decades. Implications of this evidence on different levels of prevention as well as gaps in current knowledge are also discussed. In this regard, etiological treatment has shown to be beneficial as an intervention for secondary prevention to successfully cure the infection or to delay, reduce, or prevent the progression to disease, and as primary disease prevention by breaking the chain of transmission. Timely diagnosis during initial stages would allow for the prescription of appropriate therapies mainly in the primary health care system thus improving chances for a better quality of life. Based on current evidence, etiological treatment has to be considered as an essential public health strategy useful to reduce disease burden and to eliminate Chagas disease altogether.
description Fil: Sosa-Estani, Sergio. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina.
publishDate 2012
dc.date.none.fl_str_mv 2012
dc.type.none.fl_str_mv info:ar-repo/semantics/articulo
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv 1687-9686
http://sgc.anlis.gob.ar/handle/123456789/429
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317183/pdf/JTM2012-292138.pdf
identifier_str_mv 1687-9686
url http://sgc.anlis.gob.ar/handle/123456789/429
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317183/pdf/JTM2012-292138.pdf
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of tropical medicine
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hindawi
publisher.none.fl_str_mv Hindawi
dc.source.none.fl_str_mv Journal of Tropical Medicine 2012; 2012:1-10.
reponame:Sistema de Gestión del Conocimiento ANLIS MALBRÁN
instname:Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
instacron:ANLIS
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instname_str Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
instacron_str ANLIS
institution ANLIS
repository.name.fl_str_mv Sistema de Gestión del Conocimiento ANLIS MALBRÁN - Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
repository.mail.fl_str_mv biblioteca@anlis.gov.ar
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