Therapy of Chagas Disease: Implications for Levels of Prevention
- Autores
- Sosa-Estani, Sergio Alejandro; Colantonio, Lisandro Damián; Segura, Elsa Leonor
- Año de publicación
- 2012
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- This paper reviews the evidence supporting the use of etiological treatment for Chagas disease that has changed the standard of care for patients with Trypanosoma cruzi infection in the last decades. Implications of this evidence on different levels of prevention as well as gaps in current knowledge are also discussed. In this regard, etiological treatment has shown to be beneficial as an intervention for secondary prevention to successfully cure the infection or to delay, reduce, or prevent the progression to disease, and as primary disease prevention by breaking the chain of transmission. Timely diagnosis during initial stages would allow for the prescription of appropriate therapies mainly in the primary health care system thus improving chances for a better quality of life. Based on current evidence, etiological treatment has to be considered as an essential public health strategy useful to reduce disease burden and to eliminate Chagas disease altogether.
Fil: Sosa-Estani, Sergio Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán". Instituto Nacional de Parasitología "Dr. Mario Fatala Chaben"; Argentina. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Colantonio, Lisandro Damián. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Salud Publica.; Argentina
Fil: Segura, Elsa Leonor. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán". Instituto Nacional de Parasitología "Dr. Mario Fatala Chaben"; Argentina - Materia
-
EVIDENCE SUPPORTING ETIOLOGICAL TREATMENT FOR CHAGAS
SECONDARY PREVENTION TO SUCCESFULLY CURE
TREATMENT HAS TO BE CONSIDERED AN ESSENTIAL PUBLIC HEALTH STRATEGY - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/257923
Ver los metadatos del registro completo
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spelling |
Therapy of Chagas Disease: Implications for Levels of PreventionSosa-Estani, Sergio AlejandroColantonio, Lisandro DamiánSegura, Elsa LeonorEVIDENCE SUPPORTING ETIOLOGICAL TREATMENT FOR CHAGASSECONDARY PREVENTION TO SUCCESFULLY CURETREATMENT HAS TO BE CONSIDERED AN ESSENTIAL PUBLIC HEALTH STRATEGYhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3This paper reviews the evidence supporting the use of etiological treatment for Chagas disease that has changed the standard of care for patients with Trypanosoma cruzi infection in the last decades. Implications of this evidence on different levels of prevention as well as gaps in current knowledge are also discussed. In this regard, etiological treatment has shown to be beneficial as an intervention for secondary prevention to successfully cure the infection or to delay, reduce, or prevent the progression to disease, and as primary disease prevention by breaking the chain of transmission. Timely diagnosis during initial stages would allow for the prescription of appropriate therapies mainly in the primary health care system thus improving chances for a better quality of life. Based on current evidence, etiological treatment has to be considered as an essential public health strategy useful to reduce disease burden and to eliminate Chagas disease altogether.Fil: Sosa-Estani, Sergio Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán". Instituto Nacional de Parasitología "Dr. Mario Fatala Chaben"; Argentina. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Colantonio, Lisandro Damián. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Salud Publica.; ArgentinaFil: Segura, Elsa Leonor. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán". Instituto Nacional de Parasitología "Dr. Mario Fatala Chaben"; ArgentinaWiley2012-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/257923Sosa-Estani, Sergio Alejandro; Colantonio, Lisandro Damián; Segura, Elsa Leonor; Therapy of Chagas Disease: Implications for Levels of Prevention; Wiley; Journal of Tropical Medicine; 2012; 3-2012; 1-101687-9694CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1155/2012/292138info:eu-repo/semantics/altIdentifier/doi/10.1155/2012/292138info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:45:17Zoai:ri.conicet.gov.ar:11336/257923instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:45:17.438CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Therapy of Chagas Disease: Implications for Levels of Prevention |
title |
Therapy of Chagas Disease: Implications for Levels of Prevention |
spellingShingle |
Therapy of Chagas Disease: Implications for Levels of Prevention Sosa-Estani, Sergio Alejandro EVIDENCE SUPPORTING ETIOLOGICAL TREATMENT FOR CHAGAS SECONDARY PREVENTION TO SUCCESFULLY CURE TREATMENT HAS TO BE CONSIDERED AN ESSENTIAL PUBLIC HEALTH STRATEGY |
title_short |
Therapy of Chagas Disease: Implications for Levels of Prevention |
title_full |
Therapy of Chagas Disease: Implications for Levels of Prevention |
title_fullStr |
Therapy of Chagas Disease: Implications for Levels of Prevention |
title_full_unstemmed |
Therapy of Chagas Disease: Implications for Levels of Prevention |
title_sort |
Therapy of Chagas Disease: Implications for Levels of Prevention |
dc.creator.none.fl_str_mv |
Sosa-Estani, Sergio Alejandro Colantonio, Lisandro Damián Segura, Elsa Leonor |
author |
Sosa-Estani, Sergio Alejandro |
author_facet |
Sosa-Estani, Sergio Alejandro Colantonio, Lisandro Damián Segura, Elsa Leonor |
author_role |
author |
author2 |
Colantonio, Lisandro Damián Segura, Elsa Leonor |
author2_role |
author author |
dc.subject.none.fl_str_mv |
EVIDENCE SUPPORTING ETIOLOGICAL TREATMENT FOR CHAGAS SECONDARY PREVENTION TO SUCCESFULLY CURE TREATMENT HAS TO BE CONSIDERED AN ESSENTIAL PUBLIC HEALTH STRATEGY |
topic |
EVIDENCE SUPPORTING ETIOLOGICAL TREATMENT FOR CHAGAS SECONDARY PREVENTION TO SUCCESFULLY CURE TREATMENT HAS TO BE CONSIDERED AN ESSENTIAL PUBLIC HEALTH STRATEGY |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.3 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
This paper reviews the evidence supporting the use of etiological treatment for Chagas disease that has changed the standard of care for patients with Trypanosoma cruzi infection in the last decades. Implications of this evidence on different levels of prevention as well as gaps in current knowledge are also discussed. In this regard, etiological treatment has shown to be beneficial as an intervention for secondary prevention to successfully cure the infection or to delay, reduce, or prevent the progression to disease, and as primary disease prevention by breaking the chain of transmission. Timely diagnosis during initial stages would allow for the prescription of appropriate therapies mainly in the primary health care system thus improving chances for a better quality of life. Based on current evidence, etiological treatment has to be considered as an essential public health strategy useful to reduce disease burden and to eliminate Chagas disease altogether. Fil: Sosa-Estani, Sergio Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán". Instituto Nacional de Parasitología "Dr. Mario Fatala Chaben"; Argentina. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Colantonio, Lisandro Damián. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Salud Publica.; Argentina Fil: Segura, Elsa Leonor. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán". Instituto Nacional de Parasitología "Dr. Mario Fatala Chaben"; Argentina |
description |
This paper reviews the evidence supporting the use of etiological treatment for Chagas disease that has changed the standard of care for patients with Trypanosoma cruzi infection in the last decades. Implications of this evidence on different levels of prevention as well as gaps in current knowledge are also discussed. In this regard, etiological treatment has shown to be beneficial as an intervention for secondary prevention to successfully cure the infection or to delay, reduce, or prevent the progression to disease, and as primary disease prevention by breaking the chain of transmission. Timely diagnosis during initial stages would allow for the prescription of appropriate therapies mainly in the primary health care system thus improving chances for a better quality of life. Based on current evidence, etiological treatment has to be considered as an essential public health strategy useful to reduce disease burden and to eliminate Chagas disease altogether. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-03 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/257923 Sosa-Estani, Sergio Alejandro; Colantonio, Lisandro Damián; Segura, Elsa Leonor; Therapy of Chagas Disease: Implications for Levels of Prevention; Wiley; Journal of Tropical Medicine; 2012; 3-2012; 1-10 1687-9694 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/257923 |
identifier_str_mv |
Sosa-Estani, Sergio Alejandro; Colantonio, Lisandro Damián; Segura, Elsa Leonor; Therapy of Chagas Disease: Implications for Levels of Prevention; Wiley; Journal of Tropical Medicine; 2012; 3-2012; 1-10 1687-9694 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1155/2012/292138 info:eu-repo/semantics/altIdentifier/doi/10.1155/2012/292138 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Wiley |
publisher.none.fl_str_mv |
Wiley |
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CONICET Digital (CONICET) |
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CONICET Digital (CONICET) |
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Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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13.13397 |