Therapy of Chagas Disease: Implications for Levels of Prevention

Autores
Sosa-Estani, Sergio Alejandro; Colantonio, Lisandro Damián; Segura, Elsa Leonor
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
This paper reviews the evidence supporting the use of etiological treatment for Chagas disease that has changed the standard of care for patients with Trypanosoma cruzi infection in the last decades. Implications of this evidence on different levels of prevention as well as gaps in current knowledge are also discussed. In this regard, etiological treatment has shown to be beneficial as an intervention for secondary prevention to successfully cure the infection or to delay, reduce, or prevent the progression to disease, and as primary disease prevention by breaking the chain of transmission. Timely diagnosis during initial stages would allow for the prescription of appropriate therapies mainly in the primary health care system thus improving chances for a better quality of life. Based on current evidence, etiological treatment has to be considered as an essential public health strategy useful to reduce disease burden and to eliminate Chagas disease altogether.
Fil: Sosa-Estani, Sergio Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán". Instituto Nacional de Parasitología "Dr. Mario Fatala Chaben"; Argentina. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Colantonio, Lisandro Damián. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Salud Publica.; Argentina
Fil: Segura, Elsa Leonor. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán". Instituto Nacional de Parasitología "Dr. Mario Fatala Chaben"; Argentina
Materia
EVIDENCE SUPPORTING ETIOLOGICAL TREATMENT FOR CHAGAS
SECONDARY PREVENTION TO SUCCESFULLY CURE
TREATMENT HAS TO BE CONSIDERED AN ESSENTIAL PUBLIC HEALTH STRATEGY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/257923
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Therapy of Chagas Disease: Implications for Levels of PreventionSosa-Estani, Sergio AlejandroColantonio, Lisandro DamiánSegura, Elsa LeonorEVIDENCE SUPPORTING ETIOLOGICAL TREATMENT FOR CHAGASSECONDARY PREVENTION TO SUCCESFULLY CURETREATMENT HAS TO BE CONSIDERED AN ESSENTIAL PUBLIC HEALTH STRATEGYhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3This paper reviews the evidence supporting the use of etiological treatment for Chagas disease that has changed the standard of care for patients with Trypanosoma cruzi infection in the last decades. Implications of this evidence on different levels of prevention as well as gaps in current knowledge are also discussed. In this regard, etiological treatment has shown to be beneficial as an intervention for secondary prevention to successfully cure the infection or to delay, reduce, or prevent the progression to disease, and as primary disease prevention by breaking the chain of transmission. Timely diagnosis during initial stages would allow for the prescription of appropriate therapies mainly in the primary health care system thus improving chances for a better quality of life. Based on current evidence, etiological treatment has to be considered as an essential public health strategy useful to reduce disease burden and to eliminate Chagas disease altogether.Fil: Sosa-Estani, Sergio Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán". Instituto Nacional de Parasitología "Dr. Mario Fatala Chaben"; Argentina. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Colantonio, Lisandro Damián. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Salud Publica.; ArgentinaFil: Segura, Elsa Leonor. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán". Instituto Nacional de Parasitología "Dr. Mario Fatala Chaben"; ArgentinaWiley2012-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/257923Sosa-Estani, Sergio Alejandro; Colantonio, Lisandro Damián; Segura, Elsa Leonor; Therapy of Chagas Disease: Implications for Levels of Prevention; Wiley; Journal of Tropical Medicine; 2012; 3-2012; 1-101687-9694CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1155/2012/292138info:eu-repo/semantics/altIdentifier/doi/10.1155/2012/292138info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:35:41Zoai:ri.conicet.gov.ar:11336/257923instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:35:41.579CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Therapy of Chagas Disease: Implications for Levels of Prevention
title Therapy of Chagas Disease: Implications for Levels of Prevention
spellingShingle Therapy of Chagas Disease: Implications for Levels of Prevention
Sosa-Estani, Sergio Alejandro
EVIDENCE SUPPORTING ETIOLOGICAL TREATMENT FOR CHAGAS
SECONDARY PREVENTION TO SUCCESFULLY CURE
TREATMENT HAS TO BE CONSIDERED AN ESSENTIAL PUBLIC HEALTH STRATEGY
title_short Therapy of Chagas Disease: Implications for Levels of Prevention
title_full Therapy of Chagas Disease: Implications for Levels of Prevention
title_fullStr Therapy of Chagas Disease: Implications for Levels of Prevention
title_full_unstemmed Therapy of Chagas Disease: Implications for Levels of Prevention
title_sort Therapy of Chagas Disease: Implications for Levels of Prevention
dc.creator.none.fl_str_mv Sosa-Estani, Sergio Alejandro
Colantonio, Lisandro Damián
Segura, Elsa Leonor
author Sosa-Estani, Sergio Alejandro
author_facet Sosa-Estani, Sergio Alejandro
Colantonio, Lisandro Damián
Segura, Elsa Leonor
author_role author
author2 Colantonio, Lisandro Damián
Segura, Elsa Leonor
author2_role author
author
dc.subject.none.fl_str_mv EVIDENCE SUPPORTING ETIOLOGICAL TREATMENT FOR CHAGAS
SECONDARY PREVENTION TO SUCCESFULLY CURE
TREATMENT HAS TO BE CONSIDERED AN ESSENTIAL PUBLIC HEALTH STRATEGY
topic EVIDENCE SUPPORTING ETIOLOGICAL TREATMENT FOR CHAGAS
SECONDARY PREVENTION TO SUCCESFULLY CURE
TREATMENT HAS TO BE CONSIDERED AN ESSENTIAL PUBLIC HEALTH STRATEGY
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv This paper reviews the evidence supporting the use of etiological treatment for Chagas disease that has changed the standard of care for patients with Trypanosoma cruzi infection in the last decades. Implications of this evidence on different levels of prevention as well as gaps in current knowledge are also discussed. In this regard, etiological treatment has shown to be beneficial as an intervention for secondary prevention to successfully cure the infection or to delay, reduce, or prevent the progression to disease, and as primary disease prevention by breaking the chain of transmission. Timely diagnosis during initial stages would allow for the prescription of appropriate therapies mainly in the primary health care system thus improving chances for a better quality of life. Based on current evidence, etiological treatment has to be considered as an essential public health strategy useful to reduce disease burden and to eliminate Chagas disease altogether.
Fil: Sosa-Estani, Sergio Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán". Instituto Nacional de Parasitología "Dr. Mario Fatala Chaben"; Argentina. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Colantonio, Lisandro Damián. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Salud Publica.; Argentina
Fil: Segura, Elsa Leonor. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán". Instituto Nacional de Parasitología "Dr. Mario Fatala Chaben"; Argentina
description This paper reviews the evidence supporting the use of etiological treatment for Chagas disease that has changed the standard of care for patients with Trypanosoma cruzi infection in the last decades. Implications of this evidence on different levels of prevention as well as gaps in current knowledge are also discussed. In this regard, etiological treatment has shown to be beneficial as an intervention for secondary prevention to successfully cure the infection or to delay, reduce, or prevent the progression to disease, and as primary disease prevention by breaking the chain of transmission. Timely diagnosis during initial stages would allow for the prescription of appropriate therapies mainly in the primary health care system thus improving chances for a better quality of life. Based on current evidence, etiological treatment has to be considered as an essential public health strategy useful to reduce disease burden and to eliminate Chagas disease altogether.
publishDate 2012
dc.date.none.fl_str_mv 2012-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/257923
Sosa-Estani, Sergio Alejandro; Colantonio, Lisandro Damián; Segura, Elsa Leonor; Therapy of Chagas Disease: Implications for Levels of Prevention; Wiley; Journal of Tropical Medicine; 2012; 3-2012; 1-10
1687-9694
CONICET Digital
CONICET
url http://hdl.handle.net/11336/257923
identifier_str_mv Sosa-Estani, Sergio Alejandro; Colantonio, Lisandro Damián; Segura, Elsa Leonor; Therapy of Chagas Disease: Implications for Levels of Prevention; Wiley; Journal of Tropical Medicine; 2012; 3-2012; 1-10
1687-9694
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1155/2012/292138
info:eu-repo/semantics/altIdentifier/doi/10.1155/2012/292138
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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