Simulation-model evaluation of bovine tuberculosis-eradication strategies in Argentine dairy herds

Autores
Perez, Andres M; Ward, Michael P; Ritacco, Viviana
Año de publicación
2002
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Fil: Perez, Andres M. School of Veterinary Medicine, National University of Rosario (UNR); Argentina.
Fil: Ward, Michael P. Department of Veterinary Pathobiology, School of Veterinary Medicine, 1243 Veterinary Pathobiology Building, Purdue University; Estados Unidos.
Fil: Ritacco, Viviana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.
We used stochastic modification of the Reed-Frost model to assess the impact of 14 different eradication strategies on bovine tuberculosis, under three scenarios of disease introduction, in Argentine dairy herds. All strategies investigated were based on a test-and-cull approach using either the caudal-fold test (CFT), the single cervical test (SCT), the gamma-interferon (gamma-IFN) test or a combination of these tests. The maximum, minimum and most-likely sensitivity and specificity were investigated in three scenarios simulating different epidemiological conditions. Simulation results were highly variable; therefore, it is difficult to predict the effect of disease-control strategies within individual herds. On average, the use of the SCT was less efficient in eradicating tuberculosis from the simulated herd than the CFT. Eradication would be achieved most efficiently by strategies in which the CFT was used assuming maximum possible sensitivity and specificity (difficult to achieve in the field) and/or the gamma-IFN test-which has both economical and logistical limitations to its widespread application in Argentina. When disease-control was simulated in situations in which herd tuberculosis prevalence is > or = 22%, all strategies we simulated were less efficient than herd depopulation. Considering that Argentine dairy producers are not compensated financially for cattle culled because of tuberculosis, eradication strategies currently used in the Argentine national tuberculosis eradication might not succeed.
Fuente
Preventive Veterinary Medicine 2002; 54(4):351-60.
Materia
Tuberculosis Bovina
Mycobacterium tuberculosis
Nivel de accesibilidad
acceso abierto
Condiciones de uso
none
Repositorio
Sistema de Gestión del Conocimiento ANLIS MALBRÁN
Institución
Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
OAI Identificador
oai:sgc.anlis.gob.ar:123456789/1908

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spelling Simulation-model evaluation of bovine tuberculosis-eradication strategies in Argentine dairy herdsPerez, Andres MWard, Michael PRitacco, VivianaTuberculosis BovinaMycobacterium tuberculosisFil: Perez, Andres M. School of Veterinary Medicine, National University of Rosario (UNR); Argentina.Fil: Ward, Michael P. Department of Veterinary Pathobiology, School of Veterinary Medicine, 1243 Veterinary Pathobiology Building, Purdue University; Estados Unidos.Fil: Ritacco, Viviana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.We used stochastic modification of the Reed-Frost model to assess the impact of 14 different eradication strategies on bovine tuberculosis, under three scenarios of disease introduction, in Argentine dairy herds. All strategies investigated were based on a test-and-cull approach using either the caudal-fold test (CFT), the single cervical test (SCT), the gamma-interferon (gamma-IFN) test or a combination of these tests. The maximum, minimum and most-likely sensitivity and specificity were investigated in three scenarios simulating different epidemiological conditions. Simulation results were highly variable; therefore, it is difficult to predict the effect of disease-control strategies within individual herds. On average, the use of the SCT was less efficient in eradicating tuberculosis from the simulated herd than the CFT. Eradication would be achieved most efficiently by strategies in which the CFT was used assuming maximum possible sensitivity and specificity (difficult to achieve in the field) and/or the gamma-IFN test-which has both economical and logistical limitations to its widespread application in Argentina. When disease-control was simulated in situations in which herd tuberculosis prevalence is > or = 22%, all strategies we simulated were less efficient than herd depopulation. Considering that Argentine dairy producers are not compensated financially for cattle culled because of tuberculosis, eradication strategies currently used in the Argentine national tuberculosis eradication might not succeed.2002-08-30info:ar-repo/semantics/articuloinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdf0167-5877http://sgc.anlis.gob.ar/handle/123456789/190810.1016/s0167-5877(02)00044-2Preventive Veterinary Medicine 2002; 54(4):351-60.reponame:Sistema de Gestión del Conocimiento ANLIS MALBRÁNinstname:Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"instacron:ANLISPreventive veterinary medicinenoneinfo:eu-repo/semantics/openAccesseng2025-09-29T14:30:30Zoai:sgc.anlis.gob.ar:123456789/1908Institucionalhttp://sgc.anlis.gob.ar/Organismo científico-tecnológicoNo correspondehttp://sgc.anlis.gob.ar/oai/biblioteca@anlis.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:a2025-09-29 14:30:31.097Sistema de Gestión del Conocimiento ANLIS MALBRÁN - Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"false
dc.title.none.fl_str_mv Simulation-model evaluation of bovine tuberculosis-eradication strategies in Argentine dairy herds
title Simulation-model evaluation of bovine tuberculosis-eradication strategies in Argentine dairy herds
spellingShingle Simulation-model evaluation of bovine tuberculosis-eradication strategies in Argentine dairy herds
Perez, Andres M
Tuberculosis Bovina
Mycobacterium tuberculosis
title_short Simulation-model evaluation of bovine tuberculosis-eradication strategies in Argentine dairy herds
title_full Simulation-model evaluation of bovine tuberculosis-eradication strategies in Argentine dairy herds
title_fullStr Simulation-model evaluation of bovine tuberculosis-eradication strategies in Argentine dairy herds
title_full_unstemmed Simulation-model evaluation of bovine tuberculosis-eradication strategies in Argentine dairy herds
title_sort Simulation-model evaluation of bovine tuberculosis-eradication strategies in Argentine dairy herds
dc.creator.none.fl_str_mv Perez, Andres M
Ward, Michael P
Ritacco, Viviana
author Perez, Andres M
author_facet Perez, Andres M
Ward, Michael P
Ritacco, Viviana
author_role author
author2 Ward, Michael P
Ritacco, Viviana
author2_role author
author
dc.subject.none.fl_str_mv Tuberculosis Bovina
Mycobacterium tuberculosis
topic Tuberculosis Bovina
Mycobacterium tuberculosis
dc.description.none.fl_txt_mv Fil: Perez, Andres M. School of Veterinary Medicine, National University of Rosario (UNR); Argentina.
Fil: Ward, Michael P. Department of Veterinary Pathobiology, School of Veterinary Medicine, 1243 Veterinary Pathobiology Building, Purdue University; Estados Unidos.
Fil: Ritacco, Viviana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.
We used stochastic modification of the Reed-Frost model to assess the impact of 14 different eradication strategies on bovine tuberculosis, under three scenarios of disease introduction, in Argentine dairy herds. All strategies investigated were based on a test-and-cull approach using either the caudal-fold test (CFT), the single cervical test (SCT), the gamma-interferon (gamma-IFN) test or a combination of these tests. The maximum, minimum and most-likely sensitivity and specificity were investigated in three scenarios simulating different epidemiological conditions. Simulation results were highly variable; therefore, it is difficult to predict the effect of disease-control strategies within individual herds. On average, the use of the SCT was less efficient in eradicating tuberculosis from the simulated herd than the CFT. Eradication would be achieved most efficiently by strategies in which the CFT was used assuming maximum possible sensitivity and specificity (difficult to achieve in the field) and/or the gamma-IFN test-which has both economical and logistical limitations to its widespread application in Argentina. When disease-control was simulated in situations in which herd tuberculosis prevalence is > or = 22%, all strategies we simulated were less efficient than herd depopulation. Considering that Argentine dairy producers are not compensated financially for cattle culled because of tuberculosis, eradication strategies currently used in the Argentine national tuberculosis eradication might not succeed.
description Fil: Perez, Andres M. School of Veterinary Medicine, National University of Rosario (UNR); Argentina.
publishDate 2002
dc.date.none.fl_str_mv 2002-08-30
dc.type.none.fl_str_mv info:ar-repo/semantics/articulo
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv 0167-5877
http://sgc.anlis.gob.ar/handle/123456789/1908
10.1016/s0167-5877(02)00044-2
identifier_str_mv 0167-5877
10.1016/s0167-5877(02)00044-2
url http://sgc.anlis.gob.ar/handle/123456789/1908
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Preventive veterinary medicine
dc.rights.none.fl_str_mv none
info:eu-repo/semantics/openAccess
rights_invalid_str_mv none
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Preventive Veterinary Medicine 2002; 54(4):351-60.
reponame:Sistema de Gestión del Conocimiento ANLIS MALBRÁN
instname:Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
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