Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifers

Autores
Perri, Adrián Francisco; Mejía, Miguel E.; Licoff, Nicolas; Diab, Santiago; Formía, Néstor Fabián; Ornstein, Ana María; Becú de Villalobos, Damasia; Lacau Mengido, Isabel M.
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Parasitism during development impairs normal growth and delays the onset of puberty through altered hormone profiles, including insulin-like growth factor one (IGF-1). Asmammary gland development during prepuberty is strongly dependent on IGF-1, we determined if antiparasitic treatment during this stage of growth improved mammary gland development. One group of Holstein heifers was treated monthly, rotationally with antiparasitic drugs from birth to 70 weeks of age, a second group was untreated. Treated heifer calves had between 56% and 65% less EPG counts than untreated ones. Presence of Ostertagia, Cooperia, Haemonchus and Trichostrongylus was demonstrated. Treatment effectively advanced the onset of puberty and increased IGF-1 levels. At 20, 30, 40 and 70 weeks of age biopsies from the mammary gland were taken and histological sections were prepared and stained with hematoxylin–eosin. Pictures were analyzed to compare parenchyma area in relation to total mammary tissue between groups. Mammary samples from treated heifers had higher ratios of parenchyma/total area than untreated ones. As mammary development during prepuberty is crucial for mammary performance during lactation, these results add new evidence to the importance of gastrointestinal parasite control in heifers.
Escuela de Agricultura y Ganadería "María Cruz y Manuel L. Inchausti"
Facultad de Ciencias Veterinarias
Materia
Ciencias Veterinarias
Gastrointestinal parasites
Puberty
IGF-1
Mammary development
Dairy heifers
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/104605
Acceder
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network_name_str SEDICI (UNLP)
spelling Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifersPerri, Adrián FranciscoMejía, Miguel E.Licoff, NicolasDiab, SantiagoFormía, Néstor FabiánOrnstein, Ana MaríaBecú de Villalobos, DamasiaLacau Mengido, Isabel M.Ciencias VeterinariasGastrointestinal parasitesPubertyIGF-1Mammary developmentDairy heifersParasitism during development impairs normal growth and delays the onset of puberty through altered hormone profiles, including insulin-like growth factor one (IGF-1). Asmammary gland development during prepuberty is strongly dependent on IGF-1, we determined if antiparasitic treatment during this stage of growth improved mammary gland development. One group of Holstein heifers was treated monthly, rotationally with antiparasitic drugs from birth to 70 weeks of age, a second group was untreated. Treated heifer calves had between 56% and 65% less EPG counts than untreated ones. Presence of Ostertagia, Cooperia, Haemonchus and Trichostrongylus was demonstrated. Treatment effectively advanced the onset of puberty and increased IGF-1 levels. At 20, 30, 40 and 70 weeks of age biopsies from the mammary gland were taken and histological sections were prepared and stained with hematoxylin–eosin. Pictures were analyzed to compare parenchyma area in relation to total mammary tissue between groups. Mammary samples from treated heifers had higher ratios of parenchyma/total area than untreated ones. As mammary development during prepuberty is crucial for mammary performance during lactation, these results add new evidence to the importance of gastrointestinal parasite control in heifers.Escuela de Agricultura y Ganadería "María Cruz y Manuel L. Inchausti"Facultad de Ciencias Veterinarias2013-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf345-350http://sedici.unlp.edu.ar/handle/10915/104605enginfo:eu-repo/semantics/altIdentifier/url/https://ri.conicet.gov.ar/11336/1008info:eu-repo/semantics/altIdentifier/issn/0304-4017info:eu-repo/semantics/altIdentifier/doi/10.1016/j.vetpar.2013.09.006info:eu-repo/semantics/altIdentifier/hdl/11336/1008info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:21:05Zoai:sedici.unlp.edu.ar:10915/104605Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:21:05.684SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifers
title Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifers
spellingShingle Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifers
Perri, Adrián Francisco
Ciencias Veterinarias
Gastrointestinal parasites
Puberty
IGF-1
Mammary development
Dairy heifers
title_short Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifers
title_full Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifers
title_fullStr Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifers
title_full_unstemmed Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifers
title_sort Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in Holstein heifers
dc.creator.none.fl_str_mv Perri, Adrián Francisco
Mejía, Miguel E.
Licoff, Nicolas
Diab, Santiago
Formía, Néstor Fabián
Ornstein, Ana María
Becú de Villalobos, Damasia
Lacau Mengido, Isabel M.
author Perri, Adrián Francisco
author_facet Perri, Adrián Francisco
Mejía, Miguel E.
Licoff, Nicolas
Diab, Santiago
Formía, Néstor Fabián
Ornstein, Ana María
Becú de Villalobos, Damasia
Lacau Mengido, Isabel M.
author_role author
author2 Mejía, Miguel E.
Licoff, Nicolas
Diab, Santiago
Formía, Néstor Fabián
Ornstein, Ana María
Becú de Villalobos, Damasia
Lacau Mengido, Isabel M.
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Ciencias Veterinarias
Gastrointestinal parasites
Puberty
IGF-1
Mammary development
Dairy heifers
topic Ciencias Veterinarias
Gastrointestinal parasites
Puberty
IGF-1
Mammary development
Dairy heifers
dc.description.none.fl_txt_mv Parasitism during development impairs normal growth and delays the onset of puberty through altered hormone profiles, including insulin-like growth factor one (IGF-1). Asmammary gland development during prepuberty is strongly dependent on IGF-1, we determined if antiparasitic treatment during this stage of growth improved mammary gland development. One group of Holstein heifers was treated monthly, rotationally with antiparasitic drugs from birth to 70 weeks of age, a second group was untreated. Treated heifer calves had between 56% and 65% less EPG counts than untreated ones. Presence of Ostertagia, Cooperia, Haemonchus and Trichostrongylus was demonstrated. Treatment effectively advanced the onset of puberty and increased IGF-1 levels. At 20, 30, 40 and 70 weeks of age biopsies from the mammary gland were taken and histological sections were prepared and stained with hematoxylin–eosin. Pictures were analyzed to compare parenchyma area in relation to total mammary tissue between groups. Mammary samples from treated heifers had higher ratios of parenchyma/total area than untreated ones. As mammary development during prepuberty is crucial for mammary performance during lactation, these results add new evidence to the importance of gastrointestinal parasite control in heifers.
Escuela de Agricultura y Ganadería "María Cruz y Manuel L. Inchausti"
Facultad de Ciencias Veterinarias
description Parasitism during development impairs normal growth and delays the onset of puberty through altered hormone profiles, including insulin-like growth factor one (IGF-1). Asmammary gland development during prepuberty is strongly dependent on IGF-1, we determined if antiparasitic treatment during this stage of growth improved mammary gland development. One group of Holstein heifers was treated monthly, rotationally with antiparasitic drugs from birth to 70 weeks of age, a second group was untreated. Treated heifer calves had between 56% and 65% less EPG counts than untreated ones. Presence of Ostertagia, Cooperia, Haemonchus and Trichostrongylus was demonstrated. Treatment effectively advanced the onset of puberty and increased IGF-1 levels. At 20, 30, 40 and 70 weeks of age biopsies from the mammary gland were taken and histological sections were prepared and stained with hematoxylin–eosin. Pictures were analyzed to compare parenchyma area in relation to total mammary tissue between groups. Mammary samples from treated heifers had higher ratios of parenchyma/total area than untreated ones. As mammary development during prepuberty is crucial for mammary performance during lactation, these results add new evidence to the importance of gastrointestinal parasite control in heifers.
publishDate 2013
dc.date.none.fl_str_mv 2013-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/104605
url http://sedici.unlp.edu.ar/handle/10915/104605
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://ri.conicet.gov.ar/11336/1008
info:eu-repo/semantics/altIdentifier/issn/0304-4017
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.vetpar.2013.09.006
info:eu-repo/semantics/altIdentifier/hdl/11336/1008
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
345-350
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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