Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in holstein heifers

Autores
Perri, Adrián Francisco; Mejía, Miguel E.; Licoff, Nicolas; Diab, Santiago; Formía, Néstor; Ornstein, Ana Maria; Becu, Damasia; Lacau Mengido, Isabel M.
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Parasitism during development impairs normal growth and delays the onset of puberty through altered hormone profiles, including insulin-like growth factor one (IGF-1).Asmammary gland development during prepuberty is strongly dependent on IGF-1, we determined if antiparasitic treatment during this stage of growth improved mammary gland development. One group of Holstein heifers was treated monthly, rotationally with antiparasitic drugs from birth to 70 weeks of age, a second group was untreated. Treated heifer calves had between 56% and 65% less EPG counts than untreated ones. Presence of Ostertagia, Cooperia, Haemonchus and Trichostrongylus was demonstrated. Treatment effectively advanced the onset of puberty and increased IGF-1 levels. At 20, 30, 40 and 70 weeks of age biopsies from the mammary gland were taken and histological sections were prepared and stained with hematoxylin–eosin. Pictures were analyzed to compare parenchyma area in relation to total mammary tissue between groups. Mammary samples from treated heifers had higher ratios of parenchyma/total area than untreated ones. As mammary development during prepuberty is crucial for mammary performance during lactation, these results add new evidence to the importance of gastrointestinal parasite control in heifers
Fil: Perri, Adrián Francisco. Universidad Nacional del Litoral; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Mejía, Miguel E.. Universidad Nacional del Litoral; Argentina
Fil: Licoff, Nicolas. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Diab, Santiago. University of California; Estados Unidos
Fil: Formía, Néstor. Universidad Nacional de La Plata; Argentina
Fil: Ornstein, Ana Maria. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Becu, Damasia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Lacau Mengido, Isabel M.. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Materia
Gastrointestinal parasites
Puberty
IGF-1
Mammary development
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/1008
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/1008
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in holstein heifersPerri, Adrián FranciscoMejía, Miguel E.Licoff, NicolasDiab, SantiagoFormía, NéstorOrnstein, Ana MariaBecu, DamasiaLacau Mengido, Isabel M.Gastrointestinal parasitesPubertyIGF-1Mammary developmenthttps://purl.org/becyt/ford/4.2https://purl.org/becyt/ford/4Parasitism during development impairs normal growth and delays the onset of puberty through altered hormone profiles, including insulin-like growth factor one (IGF-1).Asmammary gland development during prepuberty is strongly dependent on IGF-1, we determined if antiparasitic treatment during this stage of growth improved mammary gland development. One group of Holstein heifers was treated monthly, rotationally with antiparasitic drugs from birth to 70 weeks of age, a second group was untreated. Treated heifer calves had between 56% and 65% less EPG counts than untreated ones. Presence of Ostertagia, Cooperia, Haemonchus and Trichostrongylus was demonstrated. Treatment effectively advanced the onset of puberty and increased IGF-1 levels. At 20, 30, 40 and 70 weeks of age biopsies from the mammary gland were taken and histological sections were prepared and stained with hematoxylin–eosin. Pictures were analyzed to compare parenchyma area in relation to total mammary tissue between groups. Mammary samples from treated heifers had higher ratios of parenchyma/total area than untreated ones. As mammary development during prepuberty is crucial for mammary performance during lactation, these results add new evidence to the importance of gastrointestinal parasite control in heifersFil: Perri, Adrián Francisco. Universidad Nacional del Litoral; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Mejía, Miguel E.. Universidad Nacional del Litoral; ArgentinaFil: Licoff, Nicolas. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Diab, Santiago. University of California; Estados UnidosFil: Formía, Néstor. Universidad Nacional de La Plata; ArgentinaFil: Ornstein, Ana Maria. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Becu, Damasia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Lacau Mengido, Isabel M.. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaElsevier Science Bv2013-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/1008Perri, Adrián Francisco; Mejía, Miguel E.; Licoff, Nicolas; Diab, Santiago; Formía, Néstor; et al.; Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in holstein heifers; Elsevier Science Bv; Veterinary Parasitology; 1985; 10-2013; 345-3500304-4017enginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.vetpar.2013.09.006info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:55:42Zoai:ri.conicet.gov.ar:11336/1008instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:55:42.873CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in holstein heifers
title Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in holstein heifers
spellingShingle Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in holstein heifers
Perri, Adrián Francisco
Gastrointestinal parasites
Puberty
IGF-1
Mammary development
title_short Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in holstein heifers
title_full Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in holstein heifers
title_fullStr Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in holstein heifers
title_full_unstemmed Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in holstein heifers
title_sort Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in holstein heifers
dc.creator.none.fl_str_mv Perri, Adrián Francisco
Mejía, Miguel E.
Licoff, Nicolas
Diab, Santiago
Formía, Néstor
Ornstein, Ana Maria
Becu, Damasia
Lacau Mengido, Isabel M.
author Perri, Adrián Francisco
author_facet Perri, Adrián Francisco
Mejía, Miguel E.
Licoff, Nicolas
Diab, Santiago
Formía, Néstor
Ornstein, Ana Maria
Becu, Damasia
Lacau Mengido, Isabel M.
author_role author
author2 Mejía, Miguel E.
Licoff, Nicolas
Diab, Santiago
Formía, Néstor
Ornstein, Ana Maria
Becu, Damasia
Lacau Mengido, Isabel M.
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Gastrointestinal parasites
Puberty
IGF-1
Mammary development
topic Gastrointestinal parasites
Puberty
IGF-1
Mammary development
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.2
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv Parasitism during development impairs normal growth and delays the onset of puberty through altered hormone profiles, including insulin-like growth factor one (IGF-1).Asmammary gland development during prepuberty is strongly dependent on IGF-1, we determined if antiparasitic treatment during this stage of growth improved mammary gland development. One group of Holstein heifers was treated monthly, rotationally with antiparasitic drugs from birth to 70 weeks of age, a second group was untreated. Treated heifer calves had between 56% and 65% less EPG counts than untreated ones. Presence of Ostertagia, Cooperia, Haemonchus and Trichostrongylus was demonstrated. Treatment effectively advanced the onset of puberty and increased IGF-1 levels. At 20, 30, 40 and 70 weeks of age biopsies from the mammary gland were taken and histological sections were prepared and stained with hematoxylin–eosin. Pictures were analyzed to compare parenchyma area in relation to total mammary tissue between groups. Mammary samples from treated heifers had higher ratios of parenchyma/total area than untreated ones. As mammary development during prepuberty is crucial for mammary performance during lactation, these results add new evidence to the importance of gastrointestinal parasite control in heifers
Fil: Perri, Adrián Francisco. Universidad Nacional del Litoral; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Mejía, Miguel E.. Universidad Nacional del Litoral; Argentina
Fil: Licoff, Nicolas. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Diab, Santiago. University of California; Estados Unidos
Fil: Formía, Néstor. Universidad Nacional de La Plata; Argentina
Fil: Ornstein, Ana Maria. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Becu, Damasia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Lacau Mengido, Isabel M.. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
description Parasitism during development impairs normal growth and delays the onset of puberty through altered hormone profiles, including insulin-like growth factor one (IGF-1).Asmammary gland development during prepuberty is strongly dependent on IGF-1, we determined if antiparasitic treatment during this stage of growth improved mammary gland development. One group of Holstein heifers was treated monthly, rotationally with antiparasitic drugs from birth to 70 weeks of age, a second group was untreated. Treated heifer calves had between 56% and 65% less EPG counts than untreated ones. Presence of Ostertagia, Cooperia, Haemonchus and Trichostrongylus was demonstrated. Treatment effectively advanced the onset of puberty and increased IGF-1 levels. At 20, 30, 40 and 70 weeks of age biopsies from the mammary gland were taken and histological sections were prepared and stained with hematoxylin–eosin. Pictures were analyzed to compare parenchyma area in relation to total mammary tissue between groups. Mammary samples from treated heifers had higher ratios of parenchyma/total area than untreated ones. As mammary development during prepuberty is crucial for mammary performance during lactation, these results add new evidence to the importance of gastrointestinal parasite control in heifers
publishDate 2013
dc.date.none.fl_str_mv 2013-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/1008
Perri, Adrián Francisco; Mejía, Miguel E.; Licoff, Nicolas; Diab, Santiago; Formía, Néstor; et al.; Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in holstein heifers; Elsevier Science Bv; Veterinary Parasitology; 1985; 10-2013; 345-350
0304-4017
url http://hdl.handle.net/11336/1008
identifier_str_mv Perri, Adrián Francisco; Mejía, Miguel E.; Licoff, Nicolas; Diab, Santiago; Formía, Néstor; et al.; Gastrointestinal parasite control during prepuberty improves mammary parenchyma development in holstein heifers; Elsevier Science Bv; Veterinary Parasitology; 1985; 10-2013; 345-350
0304-4017
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.vetpar.2013.09.006
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science Bv
publisher.none.fl_str_mv Elsevier Science Bv
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844613677634813952
score 13.070432

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