Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays

Autores
Suárez, Santiago E.; Aphalo, Paula; Rinaldi, Gustavo; Quiroga, Alejandra Viviana; Añón, María Cristina
Año de publicación
2020
Idioma
inglés
Tipo de recurso
conjunto de datos
Estado
versión publicada
Descripción
Data set presented in this article is related to the research paper entitled “Effect of amaranth proteins on the RAS system. In vitro, in vivo and ex vivo assays”, available in Food Chemistry. In this article, we evaluated the effect on systolic blood pressure of spontaneously hypertensive rats (SHR) of different samples with amaranth proteins/peptides. The effect of these samples on RAS system was evaluated using in vitro and ex vivo assays. The concentration of renin and angiotensin converting enzyme (ACE) was evaluated using two commercial ELISA kits. Renin concentration was estimated through a direct immunoassay and ACE concentration with an immunoassay based on a competitive inhibition. In addition, the ACE inhibitory activity in plasma was evaluated using a spectrophotometric assay according to [2]. Ex vivo experiments were done with thoracic aorta extracted during the surgical procedure employed to obtain blood samples according to [3]. Data presented in this article recollect a very extensive work on how can be affect the RAS system in SHR model using amaranth protein/ peptides as potential antihypertensive samples. These data could be useful to design novel functional foods for hypertensive individuals.
Fil: Añón, María Cristina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina.
Fil: Aphalo, Paula. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina.
Fil: Quiroga, Alejandra Viviana. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos;Argentina
Fil: Quiroga, Alejandra Viviana. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina
Fil: Rinaldi, Gustavo. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina
Fil: Suárez, Santiago E.. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina
Fil: Suárez, Santiago E.. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina
Centro de Investigación y Desarrollo en Criotecnología de Alimentos
Facultad de Ciencias Médicas
Materia
Bioquímica
Amaranth proteins
Protein hydrolysates
Bioactive peptides
Renin-angiotensin system
Antihypertensive emulsions
Spontaneously hypertensive rats
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/107694
Acceder
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network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assaysSuárez, Santiago E.Aphalo, PaulaRinaldi, GustavoQuiroga, Alejandra VivianaAñón, María CristinaBioquímicahttps://purl.org/becyt/ford/1.6Amaranth proteinsProtein hydrolysatesBioactive peptidesRenin-angiotensin systemAntihypertensive emulsionsSpontaneously hypertensive ratsData set presented in this article is related to the research paper entitled “Effect of amaranth proteins on the RAS system. In vitro, in vivo and ex vivo assays”, available in Food Chemistry. In this article, we evaluated the effect on systolic blood pressure of spontaneously hypertensive rats (SHR) of different samples with amaranth proteins/peptides. The effect of these samples on RAS system was evaluated using in vitro and ex vivo assays. The concentration of renin and angiotensin converting enzyme (ACE) was evaluated using two commercial ELISA kits. Renin concentration was estimated through a direct immunoassay and ACE concentration with an immunoassay based on a competitive inhibition. In addition, the ACE inhibitory activity in plasma was evaluated using a spectrophotometric assay according to [2]. Ex vivo experiments were done with thoracic aorta extracted during the surgical procedure employed to obtain blood samples according to [3]. Data presented in this article recollect a very extensive work on how can be affect the RAS system in SHR model using amaranth protein/ peptides as potential antihypertensive samples. These data could be useful to design novel functional foods for hypertensive individuals.Fil: Añón, María Cristina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina.Fil: Aphalo, Paula. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina.Fil: Quiroga, Alejandra Viviana. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos;ArgentinaFil: Quiroga, Alejandra Viviana. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; ArgentinaFil: Rinaldi, Gustavo. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; ArgentinaFil: Suárez, Santiago E.. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; ArgentinaFil: Suárez, Santiago E.. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; ArgentinaCentro de Investigación y Desarrollo en Criotecnología de AlimentosFacultad de Ciencias Médicas2020-04info:eu-repo/semantics/publishedVersionConjunto de datoshttp://purl.org/coar/resource_type/c_ddb1info:ar-repo/semantics/conjuntoDeDatosinfo:eu-repo/semantics/dataSetapplication/pdfhttp://sedici.unlp.edu.ar/handle/10915/107694enginfo:eu-repo/semantics/altIdentifier/url/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7011023&blobtype=pdfinfo:eu-repo/semantics/altIdentifier/pmid/32071964info:eu-repo/semantics/altIdentifier/doi/10.1016/j.dib.2020.105168info:eu-repo/semantics/reference/doi/10.1016/j.foodchem.2019.125601info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-03T10:56:02Zoai:sedici.unlp.edu.ar:10915/107694Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-03 10:56:02.927SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays
title Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays
spellingShingle Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays
Suárez, Santiago E.
Bioquímica
Amaranth proteins
Protein hydrolysates
Bioactive peptides
Renin-angiotensin system
Antihypertensive emulsions
Spontaneously hypertensive rats
title_short Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays
title_full Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays
title_fullStr Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays
title_full_unstemmed Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays
title_sort Data set on effect of amaranth proteins on the RAS system: in vitro, in vivo and ex vivo assays
dc.creator.none.fl_str_mv Suárez, Santiago E.
Aphalo, Paula
Rinaldi, Gustavo
Quiroga, Alejandra Viviana
Añón, María Cristina
author Suárez, Santiago E.
author_facet Suárez, Santiago E.
Aphalo, Paula
Rinaldi, Gustavo
Quiroga, Alejandra Viviana
Añón, María Cristina
author_role author
author2 Aphalo, Paula
Rinaldi, Gustavo
Quiroga, Alejandra Viviana
Añón, María Cristina
author2_role author
author
author
author
dc.subject.none.fl_str_mv Bioquímica
Amaranth proteins
Protein hydrolysates
Bioactive peptides
Renin-angiotensin system
Antihypertensive emulsions
Spontaneously hypertensive rats
topic Bioquímica
Amaranth proteins
Protein hydrolysates
Bioactive peptides
Renin-angiotensin system
Antihypertensive emulsions
Spontaneously hypertensive rats
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
dc.description.none.fl_txt_mv Data set presented in this article is related to the research paper entitled “Effect of amaranth proteins on the RAS system. In vitro, in vivo and ex vivo assays”, available in Food Chemistry. In this article, we evaluated the effect on systolic blood pressure of spontaneously hypertensive rats (SHR) of different samples with amaranth proteins/peptides. The effect of these samples on RAS system was evaluated using in vitro and ex vivo assays. The concentration of renin and angiotensin converting enzyme (ACE) was evaluated using two commercial ELISA kits. Renin concentration was estimated through a direct immunoassay and ACE concentration with an immunoassay based on a competitive inhibition. In addition, the ACE inhibitory activity in plasma was evaluated using a spectrophotometric assay according to [2]. Ex vivo experiments were done with thoracic aorta extracted during the surgical procedure employed to obtain blood samples according to [3]. Data presented in this article recollect a very extensive work on how can be affect the RAS system in SHR model using amaranth protein/ peptides as potential antihypertensive samples. These data could be useful to design novel functional foods for hypertensive individuals.
Fil: Añón, María Cristina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina.
Fil: Aphalo, Paula. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina.
Fil: Quiroga, Alejandra Viviana. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos;Argentina
Fil: Quiroga, Alejandra Viviana. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina
Fil: Rinaldi, Gustavo. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina
Fil: Suárez, Santiago E.. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina
Fil: Suárez, Santiago E.. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina
Centro de Investigación y Desarrollo en Criotecnología de Alimentos
Facultad de Ciencias Médicas
description Data set presented in this article is related to the research paper entitled “Effect of amaranth proteins on the RAS system. In vitro, in vivo and ex vivo assays”, available in Food Chemistry. In this article, we evaluated the effect on systolic blood pressure of spontaneously hypertensive rats (SHR) of different samples with amaranth proteins/peptides. The effect of these samples on RAS system was evaluated using in vitro and ex vivo assays. The concentration of renin and angiotensin converting enzyme (ACE) was evaluated using two commercial ELISA kits. Renin concentration was estimated through a direct immunoassay and ACE concentration with an immunoassay based on a competitive inhibition. In addition, the ACE inhibitory activity in plasma was evaluated using a spectrophotometric assay according to [2]. Ex vivo experiments were done with thoracic aorta extracted during the surgical procedure employed to obtain blood samples according to [3]. Data presented in this article recollect a very extensive work on how can be affect the RAS system in SHR model using amaranth protein/ peptides as potential antihypertensive samples. These data could be useful to design novel functional foods for hypertensive individuals.
publishDate 2020
dc.date.none.fl_str_mv 2020-04
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info:ar-repo/semantics/conjuntoDeDatos
info:eu-repo/semantics/dataSet
status_str publishedVersion
format dataSet
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language eng
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info:eu-repo/semantics/altIdentifier/pmid/32071964
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.dib.2020.105168
info:eu-repo/semantics/reference/doi/10.1016/j.foodchem.2019.125601
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Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
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