An overview of vanadium and cell signaling in potential cancer treatments

Autores
Ferretti, Valeria Alejandra; León, Ignacio Esteban
Año de publicación
2022
Idioma
inglés
Tipo de recurso
reseña artículo
Estado
versión publicada
Descripción
Vanadium is an ultratrace element present in higher plants, animals, algae, and bacteria. In recent years, vanadium complexes have been studied to be considered as a representative of a new class of nonplatinum metal anticancer drugs. Nevertheless, the study of cell signaling pathways related to vanadium compounds has scarcely been reported on and reviewed thus far; this information is highly critical for identifying novel targets that play a key role in the anticancer activity of these compounds. Here, we perform a review of the activity of vanadium compounds over cell signaling pathways on cancer cells and of the underlying mechanisms, thereby providing insight into the role of these proteins as potential new molecular targets of vanadium complexes.
Centro de Química Inorgánica
Materia
Biología
Química
Vanadium biochemistry
Cell signaling
Cancer
Anticancer agents
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/154413

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network_name_str SEDICI (UNLP)
spelling An overview of vanadium and cell signaling in potential cancer treatmentsFerretti, Valeria AlejandraLeón, Ignacio EstebanBiologíaQuímicaVanadium biochemistryCell signalingCancerAnticancer agentsVanadium is an ultratrace element present in higher plants, animals, algae, and bacteria. In recent years, vanadium complexes have been studied to be considered as a representative of a new class of nonplatinum metal anticancer drugs. Nevertheless, the study of cell signaling pathways related to vanadium compounds has scarcely been reported on and reviewed thus far; this information is highly critical for identifying novel targets that play a key role in the anticancer activity of these compounds. Here, we perform a review of the activity of vanadium compounds over cell signaling pathways on cancer cells and of the underlying mechanisms, thereby providing insight into the role of these proteins as potential new molecular targets of vanadium complexes.Centro de Química Inorgánica2022info:eu-repo/semantics/reviewinfo:eu-repo/semantics/publishedVersionRevisionhttp://purl.org/coar/resource_type/c_dcae04bcinfo:ar-repo/semantics/resenaArticuloapplication/pdfhttp://sedici.unlp.edu.ar/handle/10915/154413enginfo:eu-repo/semantics/altIdentifier/issn/2304-6740info:eu-repo/semantics/altIdentifier/doi/10.3390/inorganics10040047info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:39:59Zoai:sedici.unlp.edu.ar:10915/154413Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:39:59.349SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv An overview of vanadium and cell signaling in potential cancer treatments
title An overview of vanadium and cell signaling in potential cancer treatments
spellingShingle An overview of vanadium and cell signaling in potential cancer treatments
Ferretti, Valeria Alejandra
Biología
Química
Vanadium biochemistry
Cell signaling
Cancer
Anticancer agents
title_short An overview of vanadium and cell signaling in potential cancer treatments
title_full An overview of vanadium and cell signaling in potential cancer treatments
title_fullStr An overview of vanadium and cell signaling in potential cancer treatments
title_full_unstemmed An overview of vanadium and cell signaling in potential cancer treatments
title_sort An overview of vanadium and cell signaling in potential cancer treatments
dc.creator.none.fl_str_mv Ferretti, Valeria Alejandra
León, Ignacio Esteban
author Ferretti, Valeria Alejandra
author_facet Ferretti, Valeria Alejandra
León, Ignacio Esteban
author_role author
author2 León, Ignacio Esteban
author2_role author
dc.subject.none.fl_str_mv Biología
Química
Vanadium biochemistry
Cell signaling
Cancer
Anticancer agents
topic Biología
Química
Vanadium biochemistry
Cell signaling
Cancer
Anticancer agents
dc.description.none.fl_txt_mv Vanadium is an ultratrace element present in higher plants, animals, algae, and bacteria. In recent years, vanadium complexes have been studied to be considered as a representative of a new class of nonplatinum metal anticancer drugs. Nevertheless, the study of cell signaling pathways related to vanadium compounds has scarcely been reported on and reviewed thus far; this information is highly critical for identifying novel targets that play a key role in the anticancer activity of these compounds. Here, we perform a review of the activity of vanadium compounds over cell signaling pathways on cancer cells and of the underlying mechanisms, thereby providing insight into the role of these proteins as potential new molecular targets of vanadium complexes.
Centro de Química Inorgánica
description Vanadium is an ultratrace element present in higher plants, animals, algae, and bacteria. In recent years, vanadium complexes have been studied to be considered as a representative of a new class of nonplatinum metal anticancer drugs. Nevertheless, the study of cell signaling pathways related to vanadium compounds has scarcely been reported on and reviewed thus far; this information is highly critical for identifying novel targets that play a key role in the anticancer activity of these compounds. Here, we perform a review of the activity of vanadium compounds over cell signaling pathways on cancer cells and of the underlying mechanisms, thereby providing insight into the role of these proteins as potential new molecular targets of vanadium complexes.
publishDate 2022
dc.date.none.fl_str_mv 2022
dc.type.none.fl_str_mv info:eu-repo/semantics/review
info:eu-repo/semantics/publishedVersion
Revision
http://purl.org/coar/resource_type/c_dcae04bc
info:ar-repo/semantics/resenaArticulo
format review
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/154413
url http://sedici.unlp.edu.ar/handle/10915/154413
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/2304-6740
info:eu-repo/semantics/altIdentifier/doi/10.3390/inorganics10040047
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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