An Overview of Vanadium and Cell Signaling in Potential Cancer Treatments
- Autores
- Ferretti, Valeria Alejandra; Leon, Ignacio Esteban
- Año de publicación
- 2022
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Vanadium is an ultratrace element present in higher plants, animals, algae, and bacteria. In recent years, vanadium complexes have been studied to be considered as a representative of a new class of nonplatinum metal anticancer drugs. Nevertheless, the study of cell signaling pathways related to vanadium compounds has scarcely been reported on and reviewed thus far; this information is highly critical for identifying novel targets that play a key role in the anticancer activity of these compounds. Here, we perform a review of the activity of vanadium compounds over cell signaling pathways on cancer cells and of the underlying mechanisms, thereby providing insight into the role of these proteins as potential new molecular targets of vanadium complexes.
Fil: Ferretti, Valeria Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina
Fil: Leon, Ignacio Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina - Materia
-
ANTICANCER AGENTS
CANCER
CELL SIGNALING
VANADIUM BIOCHEMISTRY - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/179023
Ver los metadatos del registro completo
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An Overview of Vanadium and Cell Signaling in Potential Cancer TreatmentsFerretti, Valeria AlejandraLeon, Ignacio EstebanANTICANCER AGENTSCANCERCELL SIGNALINGVANADIUM BIOCHEMISTRYhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Vanadium is an ultratrace element present in higher plants, animals, algae, and bacteria. In recent years, vanadium complexes have been studied to be considered as a representative of a new class of nonplatinum metal anticancer drugs. Nevertheless, the study of cell signaling pathways related to vanadium compounds has scarcely been reported on and reviewed thus far; this information is highly critical for identifying novel targets that play a key role in the anticancer activity of these compounds. Here, we perform a review of the activity of vanadium compounds over cell signaling pathways on cancer cells and of the underlying mechanisms, thereby providing insight into the role of these proteins as potential new molecular targets of vanadium complexes.Fil: Ferretti, Valeria Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; ArgentinaFil: Leon, Ignacio Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; ArgentinaMultidisciplinary Digital Publishing Institute2022-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/179023Ferretti, Valeria Alejandra; Leon, Ignacio Esteban; An Overview of Vanadium and Cell Signaling in Potential Cancer Treatments; Multidisciplinary Digital Publishing Institute; Inorganics; 10; 4; 4-2022; 1-112304-6740CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3390/inorganics10040047info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2304-6740/10/4/47info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:06:46Zoai:ri.conicet.gov.ar:11336/179023instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:06:46.9CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
An Overview of Vanadium and Cell Signaling in Potential Cancer Treatments |
title |
An Overview of Vanadium and Cell Signaling in Potential Cancer Treatments |
spellingShingle |
An Overview of Vanadium and Cell Signaling in Potential Cancer Treatments Ferretti, Valeria Alejandra ANTICANCER AGENTS CANCER CELL SIGNALING VANADIUM BIOCHEMISTRY |
title_short |
An Overview of Vanadium and Cell Signaling in Potential Cancer Treatments |
title_full |
An Overview of Vanadium and Cell Signaling in Potential Cancer Treatments |
title_fullStr |
An Overview of Vanadium and Cell Signaling in Potential Cancer Treatments |
title_full_unstemmed |
An Overview of Vanadium and Cell Signaling in Potential Cancer Treatments |
title_sort |
An Overview of Vanadium and Cell Signaling in Potential Cancer Treatments |
dc.creator.none.fl_str_mv |
Ferretti, Valeria Alejandra Leon, Ignacio Esteban |
author |
Ferretti, Valeria Alejandra |
author_facet |
Ferretti, Valeria Alejandra Leon, Ignacio Esteban |
author_role |
author |
author2 |
Leon, Ignacio Esteban |
author2_role |
author |
dc.subject.none.fl_str_mv |
ANTICANCER AGENTS CANCER CELL SIGNALING VANADIUM BIOCHEMISTRY |
topic |
ANTICANCER AGENTS CANCER CELL SIGNALING VANADIUM BIOCHEMISTRY |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
Vanadium is an ultratrace element present in higher plants, animals, algae, and bacteria. In recent years, vanadium complexes have been studied to be considered as a representative of a new class of nonplatinum metal anticancer drugs. Nevertheless, the study of cell signaling pathways related to vanadium compounds has scarcely been reported on and reviewed thus far; this information is highly critical for identifying novel targets that play a key role in the anticancer activity of these compounds. Here, we perform a review of the activity of vanadium compounds over cell signaling pathways on cancer cells and of the underlying mechanisms, thereby providing insight into the role of these proteins as potential new molecular targets of vanadium complexes. Fil: Ferretti, Valeria Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina Fil: Leon, Ignacio Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina |
description |
Vanadium is an ultratrace element present in higher plants, animals, algae, and bacteria. In recent years, vanadium complexes have been studied to be considered as a representative of a new class of nonplatinum metal anticancer drugs. Nevertheless, the study of cell signaling pathways related to vanadium compounds has scarcely been reported on and reviewed thus far; this information is highly critical for identifying novel targets that play a key role in the anticancer activity of these compounds. Here, we perform a review of the activity of vanadium compounds over cell signaling pathways on cancer cells and of the underlying mechanisms, thereby providing insight into the role of these proteins as potential new molecular targets of vanadium complexes. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-04 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/179023 Ferretti, Valeria Alejandra; Leon, Ignacio Esteban; An Overview of Vanadium and Cell Signaling in Potential Cancer Treatments; Multidisciplinary Digital Publishing Institute; Inorganics; 10; 4; 4-2022; 1-11 2304-6740 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/179023 |
identifier_str_mv |
Ferretti, Valeria Alejandra; Leon, Ignacio Esteban; An Overview of Vanadium and Cell Signaling in Potential Cancer Treatments; Multidisciplinary Digital Publishing Institute; Inorganics; 10; 4; 4-2022; 1-11 2304-6740 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.3390/inorganics10040047 info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2304-6740/10/4/47 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/2.5/ar/ |
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openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Multidisciplinary Digital Publishing Institute |
publisher.none.fl_str_mv |
Multidisciplinary Digital Publishing Institute |
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reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) |
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CONICET Digital (CONICET) |
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Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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13.070432 |