Docking Applied to the Study of Inhibitors of c-Met Kinase
- Autores
- Gavernet, Luciana; Palestro, Pablo Hernán; Bruno Blanch, Luis Enrique
- Año de publicación
- 2012
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Quinoxaline derivatives were studied as inhibitors of c-Met kinase, a receptor associated with high tumor grade and poor prognosis in a number of human cancers. In this paper we used docking methodologies to predict the binding conformation of a set of quinoxalines and to explain the differences of biological activities previously reported.
Facultad de Ciencias Exactas - Materia
-
Química
Quinoxaline
c-Met kinase
inhibitors - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- http://creativecommons.org/licenses/by/3.0/
- Repositorio
.jpg)
- Institución
- Universidad Nacional de La Plata
- OAI Identificador
- oai:sedici.unlp.edu.ar:10915/81055
Ver los metadatos del registro completo
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Docking Applied to the Study of Inhibitors of c-Met KinaseGavernet, LucianaPalestro, Pablo HernánBruno Blanch, Luis EnriqueQuímicaQuinoxalinec-Met kinaseinhibitorsQuinoxaline derivatives were studied as inhibitors of c-Met kinase, a receptor associated with high tumor grade and poor prognosis in a number of human cancers. In this paper we used docking methodologies to predict the binding conformation of a set of quinoxalines and to explain the differences of biological activities previously reported.Facultad de Ciencias Exactas2012info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://sedici.unlp.edu.ar/handle/10915/81055enginfo:eu-repo/semantics/altIdentifier/issn/2090-7761info:eu-repo/semantics/altIdentifier/doi/10.5402/2012/391897info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/3.0/Creative Commons Attribution 3.0 Unported (CC BY 3.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:15:01Zoai:sedici.unlp.edu.ar:10915/81055Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:15:01.862SEDICI (UNLP) - Universidad Nacional de La Platafalse |
| dc.title.none.fl_str_mv |
Docking Applied to the Study of Inhibitors of c-Met Kinase |
| title |
Docking Applied to the Study of Inhibitors of c-Met Kinase |
| spellingShingle |
Docking Applied to the Study of Inhibitors of c-Met Kinase Gavernet, Luciana Química Quinoxaline c-Met kinase inhibitors |
| title_short |
Docking Applied to the Study of Inhibitors of c-Met Kinase |
| title_full |
Docking Applied to the Study of Inhibitors of c-Met Kinase |
| title_fullStr |
Docking Applied to the Study of Inhibitors of c-Met Kinase |
| title_full_unstemmed |
Docking Applied to the Study of Inhibitors of c-Met Kinase |
| title_sort |
Docking Applied to the Study of Inhibitors of c-Met Kinase |
| dc.creator.none.fl_str_mv |
Gavernet, Luciana Palestro, Pablo Hernán Bruno Blanch, Luis Enrique |
| author |
Gavernet, Luciana |
| author_facet |
Gavernet, Luciana Palestro, Pablo Hernán Bruno Blanch, Luis Enrique |
| author_role |
author |
| author2 |
Palestro, Pablo Hernán Bruno Blanch, Luis Enrique |
| author2_role |
author author |
| dc.subject.none.fl_str_mv |
Química Quinoxaline c-Met kinase inhibitors |
| topic |
Química Quinoxaline c-Met kinase inhibitors |
| dc.description.none.fl_txt_mv |
Quinoxaline derivatives were studied as inhibitors of c-Met kinase, a receptor associated with high tumor grade and poor prognosis in a number of human cancers. In this paper we used docking methodologies to predict the binding conformation of a set of quinoxalines and to explain the differences of biological activities previously reported. Facultad de Ciencias Exactas |
| description |
Quinoxaline derivatives were studied as inhibitors of c-Met kinase, a receptor associated with high tumor grade and poor prognosis in a number of human cancers. In this paper we used docking methodologies to predict the binding conformation of a set of quinoxalines and to explain the differences of biological activities previously reported. |
| publishDate |
2012 |
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2012 |
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eng |
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eng |
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