The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts

Autores
Wehby, George L.; Castilla, Eduardo Enrique; Goco, Norman; Rittler, Monica; Cosentino, Viviana; Javois, Lorette; Kindem, Mark; Chakraborty, Hrishikesh; Dutra, Graca; López Camelo, Jorge Santiago; Orioli, Iêda M.; Murray, Jeffrey C.
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Cleft lip and/or palate (CL/P) increase mortality and morbidity risks for affected infants especially in less developed countries. This study aimed at assessing the effects of systematic pediatric care on neonatal mortality and hospitalizations of infants with cleft lip and/or palate (CL/P) in South America.Methods: The intervention group included live-born infants with isolated or associated CL/P in 47 hospitals between 2003 and 2005. The control group included live-born infants with CL/P between 2001 and 2002 in the same hospitals. The intervention group received systematic pediatric care between the 7 thand 28 thday of life. The primary outcomes were mortality between the 7 thand 28 thday of life and hospitalization days in this period among survivors adjusted for relevant baseline covariates.Results: There were no significant mortality differences between the intervention and control groups. However, surviving infants with associated CL/P in the intervention group had fewer hospitalization days by about six days compared to the associated control group.Conclusions: Early systematic pediatric care may significantly reduce neonatal hospitalizations of infants with CL/P and additional birth defects in South America. Given the large healthcare and financial burden of CL/P on affected families and the relatively low cost of systematic pediatric care, improving access to such care may be a cost-effective public policy intervention.
Instituto Multidisciplinario de Biología Celular
Materia
Ciencias Médicas
Cleft lip
Neonatal mortality
Early systematic pediatric care
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/84425

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network_name_str SEDICI (UNLP)
spelling The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral cleftsWehby, George L.Castilla, Eduardo EnriqueGoco, NormanRittler, MonicaCosentino, VivianaJavois, LoretteKindem, MarkChakraborty, HrishikeshDutra, GracaLópez Camelo, Jorge SantiagoOrioli, Iêda M.Murray, Jeffrey C.Ciencias MédicasCleft lipNeonatal mortalityEarly systematic pediatric careBackground: Cleft lip and/or palate (CL/P) increase mortality and morbidity risks for affected infants especially in less developed countries. This study aimed at assessing the effects of systematic pediatric care on neonatal mortality and hospitalizations of infants with cleft lip and/or palate (CL/P) in South America.Methods: The intervention group included live-born infants with isolated or associated CL/P in 47 hospitals between 2003 and 2005. The control group included live-born infants with CL/P between 2001 and 2002 in the same hospitals. The intervention group received systematic pediatric care between the 7 thand 28 thday of life. The primary outcomes were mortality between the 7 thand 28 thday of life and hospitalization days in this period among survivors adjusted for relevant baseline covariates.Results: There were no significant mortality differences between the intervention and control groups. However, surviving infants with associated CL/P in the intervention group had fewer hospitalization days by about six days compared to the associated control group.Conclusions: Early systematic pediatric care may significantly reduce neonatal hospitalizations of infants with CL/P and additional birth defects in South America. Given the large healthcare and financial burden of CL/P on affected families and the relatively low cost of systematic pediatric care, improving access to such care may be a cost-effective public policy intervention.Instituto Multidisciplinario de Biología Celular2011info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://sedici.unlp.edu.ar/handle/10915/84425enginfo:eu-repo/semantics/altIdentifier/issn/1471-2431info:eu-repo/semantics/altIdentifier/doi/10.1186/1471-2431-11-121info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:16:06Zoai:sedici.unlp.edu.ar:10915/84425Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:16:06.289SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
title The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
spellingShingle The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
Wehby, George L.
Ciencias Médicas
Cleft lip
Neonatal mortality
Early systematic pediatric care
title_short The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
title_full The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
title_fullStr The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
title_full_unstemmed The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
title_sort The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
dc.creator.none.fl_str_mv Wehby, George L.
Castilla, Eduardo Enrique
Goco, Norman
Rittler, Monica
Cosentino, Viviana
Javois, Lorette
Kindem, Mark
Chakraborty, Hrishikesh
Dutra, Graca
López Camelo, Jorge Santiago
Orioli, Iêda M.
Murray, Jeffrey C.
author Wehby, George L.
author_facet Wehby, George L.
Castilla, Eduardo Enrique
Goco, Norman
Rittler, Monica
Cosentino, Viviana
Javois, Lorette
Kindem, Mark
Chakraborty, Hrishikesh
Dutra, Graca
López Camelo, Jorge Santiago
Orioli, Iêda M.
Murray, Jeffrey C.
author_role author
author2 Castilla, Eduardo Enrique
Goco, Norman
Rittler, Monica
Cosentino, Viviana
Javois, Lorette
Kindem, Mark
Chakraborty, Hrishikesh
Dutra, Graca
López Camelo, Jorge Santiago
Orioli, Iêda M.
Murray, Jeffrey C.
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Ciencias Médicas
Cleft lip
Neonatal mortality
Early systematic pediatric care
topic Ciencias Médicas
Cleft lip
Neonatal mortality
Early systematic pediatric care
dc.description.none.fl_txt_mv Background: Cleft lip and/or palate (CL/P) increase mortality and morbidity risks for affected infants especially in less developed countries. This study aimed at assessing the effects of systematic pediatric care on neonatal mortality and hospitalizations of infants with cleft lip and/or palate (CL/P) in South America.Methods: The intervention group included live-born infants with isolated or associated CL/P in 47 hospitals between 2003 and 2005. The control group included live-born infants with CL/P between 2001 and 2002 in the same hospitals. The intervention group received systematic pediatric care between the 7 thand 28 thday of life. The primary outcomes were mortality between the 7 thand 28 thday of life and hospitalization days in this period among survivors adjusted for relevant baseline covariates.Results: There were no significant mortality differences between the intervention and control groups. However, surviving infants with associated CL/P in the intervention group had fewer hospitalization days by about six days compared to the associated control group.Conclusions: Early systematic pediatric care may significantly reduce neonatal hospitalizations of infants with CL/P and additional birth defects in South America. Given the large healthcare and financial burden of CL/P on affected families and the relatively low cost of systematic pediatric care, improving access to such care may be a cost-effective public policy intervention.
Instituto Multidisciplinario de Biología Celular
description Background: Cleft lip and/or palate (CL/P) increase mortality and morbidity risks for affected infants especially in less developed countries. This study aimed at assessing the effects of systematic pediatric care on neonatal mortality and hospitalizations of infants with cleft lip and/or palate (CL/P) in South America.Methods: The intervention group included live-born infants with isolated or associated CL/P in 47 hospitals between 2003 and 2005. The control group included live-born infants with CL/P between 2001 and 2002 in the same hospitals. The intervention group received systematic pediatric care between the 7 thand 28 thday of life. The primary outcomes were mortality between the 7 thand 28 thday of life and hospitalization days in this period among survivors adjusted for relevant baseline covariates.Results: There were no significant mortality differences between the intervention and control groups. However, surviving infants with associated CL/P in the intervention group had fewer hospitalization days by about six days compared to the associated control group.Conclusions: Early systematic pediatric care may significantly reduce neonatal hospitalizations of infants with CL/P and additional birth defects in South America. Given the large healthcare and financial burden of CL/P on affected families and the relatively low cost of systematic pediatric care, improving access to such care may be a cost-effective public policy intervention.
publishDate 2011
dc.date.none.fl_str_mv 2011
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/84425
url http://sedici.unlp.edu.ar/handle/10915/84425
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/1471-2431
info:eu-repo/semantics/altIdentifier/doi/10.1186/1471-2431-11-121
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
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