The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts

Autores
Wehby, George; Castilla, Eduardo Enrique; Goco, Norman; Rittler, Monica; Cosentino, Viviana Raquel; Javois, Lorette; Kindem, Mark; Chakraborty, Hrishikesh; Figueiredo Pereira Dutra, Maria Da Graca; López Camelo, Jorge Santiago; Orioli, Ieda Maria; Murray, Jeffrey C.
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Cleft lip and/or palate (CL/P) increase mortality and morbidity risks for affected infants especially in less developed countries. This study aimed at assessing the effects of systematic pediatric care on neonatal mortality and hospitalizations of infants with cleft lip and/or palate (CL/P) in South America.Methods: The intervention group included live-born infants with isolated or associated CL/P in 47 hospitals between 2003 and 2005. The control group included live-born infants with CL/P between 2001 and 2002 in the same hospitals. The intervention group received systematic pediatric care between the 7 th and 28 th day of life. The primary outcomes were mortality between the 7 th and 28 th day of life and hospitalization days in this period among survivors adjusted for relevant baseline covariates.Results: There were no significant mortality differences between the intervention and control groups. However, surviving infants with associated CL/P in the intervention group had fewer hospitalization days by about six days compared to the associated control group.Conclusions: Early systematic pediatric care may significantly reduce neonatal hospitalizations of infants with CL/P and additional birth defects in South America. Given the large healthcare and financial burden of CL/P on affected families and the relatively low cost of systematic pediatric care, improving access to such care may be a cost-effective public policy intervention.
Fil: Wehby, George. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina. University of Iowa; Estados Unidos
Fil: Castilla, Eduardo Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina. Instituto Oswaldo Cruz; Brasil
Fil: Goco, Norman. Research Triangle Park; Estados Unidos
Fil: Rittler, Monica. Gobierno de la Ciudad de Buenos Aires. Hospital Materno Infantil Ramón Sardá; Argentina
Fil: Cosentino, Viviana Raquel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina
Fil: Javois, Lorette. National Institutes of Health; Estados Unidos
Fil: Kindem, Mark. Research Triangle Park; Estados Unidos
Fil: Chakraborty, Hrishikesh. University of South Carolina; Estados Unidos
Fil: Figueiredo Pereira Dutra, Maria Da Graca. Instituto Oswaldo Cruz; Brasil
Fil: López Camelo, Jorge Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina
Fil: Orioli, Ieda Maria. Universidade Federal do Rio de Janeiro; Brasil
Fil: Murray, Jeffrey C.. University of Iowa; Estados Unidos
Materia
pediatric care
hospitalizations
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/95546
Acceder
id CONICETDig_b6c8c62648a70074a0d5bfef992ffd91
oai_identifier_str oai:ri.conicet.gov.ar:11336/95546
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral cleftsWehby, GeorgeCastilla, Eduardo EnriqueGoco, NormanRittler, MonicaCosentino, Viviana RaquelJavois, LoretteKindem, MarkChakraborty, HrishikeshFigueiredo Pereira Dutra, Maria Da GracaLópez Camelo, Jorge SantiagoOrioli, Ieda MariaMurray, Jeffrey C.pediatric carehospitalizationshttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Background: Cleft lip and/or palate (CL/P) increase mortality and morbidity risks for affected infants especially in less developed countries. This study aimed at assessing the effects of systematic pediatric care on neonatal mortality and hospitalizations of infants with cleft lip and/or palate (CL/P) in South America.Methods: The intervention group included live-born infants with isolated or associated CL/P in 47 hospitals between 2003 and 2005. The control group included live-born infants with CL/P between 2001 and 2002 in the same hospitals. The intervention group received systematic pediatric care between the 7 th and 28 th day of life. The primary outcomes were mortality between the 7 th and 28 th day of life and hospitalization days in this period among survivors adjusted for relevant baseline covariates.Results: There were no significant mortality differences between the intervention and control groups. However, surviving infants with associated CL/P in the intervention group had fewer hospitalization days by about six days compared to the associated control group.Conclusions: Early systematic pediatric care may significantly reduce neonatal hospitalizations of infants with CL/P and additional birth defects in South America. Given the large healthcare and financial burden of CL/P on affected families and the relatively low cost of systematic pediatric care, improving access to such care may be a cost-effective public policy intervention.Fil: Wehby, George. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina. University of Iowa; Estados UnidosFil: Castilla, Eduardo Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina. Instituto Oswaldo Cruz; BrasilFil: Goco, Norman. Research Triangle Park; Estados UnidosFil: Rittler, Monica. Gobierno de la Ciudad de Buenos Aires. Hospital Materno Infantil Ramón Sardá; ArgentinaFil: Cosentino, Viviana Raquel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; ArgentinaFil: Javois, Lorette. National Institutes of Health; Estados UnidosFil: Kindem, Mark. Research Triangle Park; Estados UnidosFil: Chakraborty, Hrishikesh. University of South Carolina; Estados UnidosFil: Figueiredo Pereira Dutra, Maria Da Graca. Instituto Oswaldo Cruz; BrasilFil: López Camelo, Jorge Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; ArgentinaFil: Orioli, Ieda Maria. Universidade Federal do Rio de Janeiro; BrasilFil: Murray, Jeffrey C.. University of Iowa; Estados UnidosBioMed Central2011-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/mswordapplication/mswordapplication/pdfhttp://hdl.handle.net/11336/95546Wehby, George; Castilla, Eduardo Enrique; Goco, Norman; Rittler, Monica; Cosentino, Viviana Raquel; et al.; The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts; BioMed Central; Bmc Pediatrics; 11; 12-2011; 121-1211471-2431CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.biomedcentral.com/1471-2431/11/121info:eu-repo/semantics/altIdentifier/doi/10.1186/1471-2431-11-121info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:03:48Zoai:ri.conicet.gov.ar:11336/95546instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:03:48.439CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
title The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
spellingShingle The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
Wehby, George
pediatric care
hospitalizations
title_short The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
title_full The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
title_fullStr The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
title_full_unstemmed The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
title_sort The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
dc.creator.none.fl_str_mv Wehby, George
Castilla, Eduardo Enrique
Goco, Norman
Rittler, Monica
Cosentino, Viviana Raquel
Javois, Lorette
Kindem, Mark
Chakraborty, Hrishikesh
Figueiredo Pereira Dutra, Maria Da Graca
López Camelo, Jorge Santiago
Orioli, Ieda Maria
Murray, Jeffrey C.
author Wehby, George
author_facet Wehby, George
Castilla, Eduardo Enrique
Goco, Norman
Rittler, Monica
Cosentino, Viviana Raquel
Javois, Lorette
Kindem, Mark
Chakraborty, Hrishikesh
Figueiredo Pereira Dutra, Maria Da Graca
López Camelo, Jorge Santiago
Orioli, Ieda Maria
Murray, Jeffrey C.
author_role author
author2 Castilla, Eduardo Enrique
Goco, Norman
Rittler, Monica
Cosentino, Viviana Raquel
Javois, Lorette
Kindem, Mark
Chakraborty, Hrishikesh
Figueiredo Pereira Dutra, Maria Da Graca
López Camelo, Jorge Santiago
Orioli, Ieda Maria
Murray, Jeffrey C.
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv pediatric care
hospitalizations
topic pediatric care
hospitalizations
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Background: Cleft lip and/or palate (CL/P) increase mortality and morbidity risks for affected infants especially in less developed countries. This study aimed at assessing the effects of systematic pediatric care on neonatal mortality and hospitalizations of infants with cleft lip and/or palate (CL/P) in South America.Methods: The intervention group included live-born infants with isolated or associated CL/P in 47 hospitals between 2003 and 2005. The control group included live-born infants with CL/P between 2001 and 2002 in the same hospitals. The intervention group received systematic pediatric care between the 7 th and 28 th day of life. The primary outcomes were mortality between the 7 th and 28 th day of life and hospitalization days in this period among survivors adjusted for relevant baseline covariates.Results: There were no significant mortality differences between the intervention and control groups. However, surviving infants with associated CL/P in the intervention group had fewer hospitalization days by about six days compared to the associated control group.Conclusions: Early systematic pediatric care may significantly reduce neonatal hospitalizations of infants with CL/P and additional birth defects in South America. Given the large healthcare and financial burden of CL/P on affected families and the relatively low cost of systematic pediatric care, improving access to such care may be a cost-effective public policy intervention.
Fil: Wehby, George. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina. University of Iowa; Estados Unidos
Fil: Castilla, Eduardo Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina. Instituto Oswaldo Cruz; Brasil
Fil: Goco, Norman. Research Triangle Park; Estados Unidos
Fil: Rittler, Monica. Gobierno de la Ciudad de Buenos Aires. Hospital Materno Infantil Ramón Sardá; Argentina
Fil: Cosentino, Viviana Raquel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina
Fil: Javois, Lorette. National Institutes of Health; Estados Unidos
Fil: Kindem, Mark. Research Triangle Park; Estados Unidos
Fil: Chakraborty, Hrishikesh. University of South Carolina; Estados Unidos
Fil: Figueiredo Pereira Dutra, Maria Da Graca. Instituto Oswaldo Cruz; Brasil
Fil: López Camelo, Jorge Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina
Fil: Orioli, Ieda Maria. Universidade Federal do Rio de Janeiro; Brasil
Fil: Murray, Jeffrey C.. University of Iowa; Estados Unidos
description Background: Cleft lip and/or palate (CL/P) increase mortality and morbidity risks for affected infants especially in less developed countries. This study aimed at assessing the effects of systematic pediatric care on neonatal mortality and hospitalizations of infants with cleft lip and/or palate (CL/P) in South America.Methods: The intervention group included live-born infants with isolated or associated CL/P in 47 hospitals between 2003 and 2005. The control group included live-born infants with CL/P between 2001 and 2002 in the same hospitals. The intervention group received systematic pediatric care between the 7 th and 28 th day of life. The primary outcomes were mortality between the 7 th and 28 th day of life and hospitalization days in this period among survivors adjusted for relevant baseline covariates.Results: There were no significant mortality differences between the intervention and control groups. However, surviving infants with associated CL/P in the intervention group had fewer hospitalization days by about six days compared to the associated control group.Conclusions: Early systematic pediatric care may significantly reduce neonatal hospitalizations of infants with CL/P and additional birth defects in South America. Given the large healthcare and financial burden of CL/P on affected families and the relatively low cost of systematic pediatric care, improving access to such care may be a cost-effective public policy intervention.
publishDate 2011
dc.date.none.fl_str_mv 2011-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/95546
Wehby, George; Castilla, Eduardo Enrique; Goco, Norman; Rittler, Monica; Cosentino, Viviana Raquel; et al.; The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts; BioMed Central; Bmc Pediatrics; 11; 12-2011; 121-121
1471-2431
CONICET Digital
CONICET
url http://hdl.handle.net/11336/95546
identifier_str_mv Wehby, George; Castilla, Eduardo Enrique; Goco, Norman; Rittler, Monica; Cosentino, Viviana Raquel; et al.; The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts; BioMed Central; Bmc Pediatrics; 11; 12-2011; 121-121
1471-2431
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.biomedcentral.com/1471-2431/11/121
info:eu-repo/semantics/altIdentifier/doi/10.1186/1471-2431-11-121
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/msword
application/msword
application/pdf
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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