Effect of inbreeding depression on bull sperm quality and field fertility

Autores
Dorado, Jesús; Morales Cid, Rosa; Molina, Antonio; Hidalgo, Manuel; Ariza, Julia; Moreno Millán, Miguel; Demyda Peyrás, Sebastián
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The present study investigated the effect of inbreeding depression on sperm quality using automated and objective methods and subsequent effects on beef bull field fertility. Individual inbreeding coefficient (F) values and field fertility data were determined using a dataset of AI bulls belonging to the Spanish Retinta Breeders Association (Asociación Nacional de Criadores de Ganado Vacuno Selecto de Raza Retinta (ANCRE)). Animals were clustered in two groups according to the F values as follows: (1) a high inbreeding group (HI; F≥13.5%, mean 16.3); and (2) a non-inbreeding group (NI; F≤0%). In total, 17 different assessments were performed in both experimental groups, including evaluation of sperm morphology, acrosomal and DNA status, sperm plasma membrane integrity and function (hypo-osmotic swelling test), 10 kinetic parameters and the structure of sperm subpopulations. Sperm morphology, acrosomal and DNA status and osmotic tolerance were similar in both groups. Three velocity parameters (curvilinear velocity, straight line velocity and average path velocity) and the amplitude of lateral head displacement were higher in HI (P<0.05). Cluster analysis of kinematic parameters revealed three different sperm subpopulations (sP1, sP2 and sP3), with the proportion of the sP1 population (highly active but non-progressive spermatozoa) being significantly (P<0.05) higher in the HI group. Field fertility was assessed using two calving record datasets. In a smaller database including only bulls evaluated in the present study, there was a significant increase in the calving interval of cows sired with HI bulls. Conversely, in an extended genetic analysis of the ANCRE database, inbreeding only explained a small part of the variation in calving interval, and the results of regression analysis were not significant among bulls. The findings of the present study suggest that high inbreeding levels have a moderate effect on bull semen quality, with an increased percentage of highly active but non-progressive spermatozoa, but only when F values reached a certain threshold. This motility pattern could explain, in part, the higher calving interval produced by inbred bulls under field conditions.
Instituto de Genética Veterinaria
Materia
Ciencias Veterinarias
Calving interval
Cattle
Computer-aided sperm analysis (CASA)
DNA fragmentation
Genetic trait
Sperm function
Sperm morphology
Sperm subpopulations.
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/101364

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oai_identifier_str oai:sedici.unlp.edu.ar:10915/101364
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network_name_str SEDICI (UNLP)
spelling Effect of inbreeding depression on bull sperm quality and field fertilityDorado, JesúsMorales Cid, RosaMolina, AntonioHidalgo, ManuelAriza, JuliaMoreno Millán, MiguelDemyda Peyrás, SebastiánCiencias VeterinariasCalving intervalCattleComputer-aided sperm analysis (CASA)DNA fragmentationGenetic traitSperm functionSperm morphologySperm subpopulations.The present study investigated the effect of inbreeding depression on sperm quality using automated and objective methods and subsequent effects on beef bull field fertility. Individual inbreeding coefficient (F) values and field fertility data were determined using a dataset of AI bulls belonging to the Spanish Retinta Breeders Association (Asociación Nacional de Criadores de Ganado Vacuno Selecto de Raza Retinta (ANCRE)). Animals were clustered in two groups according to the F values as follows: (1) a high inbreeding group (HI; F≥13.5%, mean 16.3); and (2) a non-inbreeding group (NI; F≤0%). In total, 17 different assessments were performed in both experimental groups, including evaluation of sperm morphology, acrosomal and DNA status, sperm plasma membrane integrity and function (hypo-osmotic swelling test), 10 kinetic parameters and the structure of sperm subpopulations. Sperm morphology, acrosomal and DNA status and osmotic tolerance were similar in both groups. Three velocity parameters (curvilinear velocity, straight line velocity and average path velocity) and the amplitude of lateral head displacement were higher in HI (P<0.05). Cluster analysis of kinematic parameters revealed three different sperm subpopulations (sP1, sP2 and sP3), with the proportion of the sP1 population (highly active but non-progressive spermatozoa) being significantly (P<0.05) higher in the HI group. Field fertility was assessed using two calving record datasets. In a smaller database including only bulls evaluated in the present study, there was a significant increase in the calving interval of cows sired with HI bulls. Conversely, in an extended genetic analysis of the ANCRE database, inbreeding only explained a small part of the variation in calving interval, and the results of regression analysis were not significant among bulls. The findings of the present study suggest that high inbreeding levels have a moderate effect on bull semen quality, with an increased percentage of highly active but non-progressive spermatozoa, but only when F values reached a certain threshold. This motility pattern could explain, in part, the higher calving interval produced by inbred bulls under field conditions.Instituto de Genética Veterinaria2017-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf712-720http://sedici.unlp.edu.ar/handle/10915/101364enginfo:eu-repo/semantics/altIdentifier/url/https://ri.conicet.gov.ar/11336/48139info:eu-repo/semantics/altIdentifier/url/http://www.publish.csiro.au/rd/RD15324info:eu-repo/semantics/altIdentifier/issn/1031-3613info:eu-repo/semantics/altIdentifier/doi/10.1071/RD15324info:eu-repo/semantics/altIdentifier/hdl/11336/48139info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-10-15T11:11:59Zoai:sedici.unlp.edu.ar:10915/101364Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-10-15 11:12:00.009SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Effect of inbreeding depression on bull sperm quality and field fertility
title Effect of inbreeding depression on bull sperm quality and field fertility
spellingShingle Effect of inbreeding depression on bull sperm quality and field fertility
Dorado, Jesús
Ciencias Veterinarias
Calving interval
Cattle
Computer-aided sperm analysis (CASA)
DNA fragmentation
Genetic trait
Sperm function
Sperm morphology
Sperm subpopulations.
title_short Effect of inbreeding depression on bull sperm quality and field fertility
title_full Effect of inbreeding depression on bull sperm quality and field fertility
title_fullStr Effect of inbreeding depression on bull sperm quality and field fertility
title_full_unstemmed Effect of inbreeding depression on bull sperm quality and field fertility
title_sort Effect of inbreeding depression on bull sperm quality and field fertility
dc.creator.none.fl_str_mv Dorado, Jesús
Morales Cid, Rosa
Molina, Antonio
Hidalgo, Manuel
Ariza, Julia
Moreno Millán, Miguel
Demyda Peyrás, Sebastián
author Dorado, Jesús
author_facet Dorado, Jesús
Morales Cid, Rosa
Molina, Antonio
Hidalgo, Manuel
Ariza, Julia
Moreno Millán, Miguel
Demyda Peyrás, Sebastián
author_role author
author2 Morales Cid, Rosa
Molina, Antonio
Hidalgo, Manuel
Ariza, Julia
Moreno Millán, Miguel
Demyda Peyrás, Sebastián
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Ciencias Veterinarias
Calving interval
Cattle
Computer-aided sperm analysis (CASA)
DNA fragmentation
Genetic trait
Sperm function
Sperm morphology
Sperm subpopulations.
topic Ciencias Veterinarias
Calving interval
Cattle
Computer-aided sperm analysis (CASA)
DNA fragmentation
Genetic trait
Sperm function
Sperm morphology
Sperm subpopulations.
dc.description.none.fl_txt_mv The present study investigated the effect of inbreeding depression on sperm quality using automated and objective methods and subsequent effects on beef bull field fertility. Individual inbreeding coefficient (F) values and field fertility data were determined using a dataset of AI bulls belonging to the Spanish Retinta Breeders Association (Asociación Nacional de Criadores de Ganado Vacuno Selecto de Raza Retinta (ANCRE)). Animals were clustered in two groups according to the F values as follows: (1) a high inbreeding group (HI; F≥13.5%, mean 16.3); and (2) a non-inbreeding group (NI; F≤0%). In total, 17 different assessments were performed in both experimental groups, including evaluation of sperm morphology, acrosomal and DNA status, sperm plasma membrane integrity and function (hypo-osmotic swelling test), 10 kinetic parameters and the structure of sperm subpopulations. Sperm morphology, acrosomal and DNA status and osmotic tolerance were similar in both groups. Three velocity parameters (curvilinear velocity, straight line velocity and average path velocity) and the amplitude of lateral head displacement were higher in HI (P<0.05). Cluster analysis of kinematic parameters revealed three different sperm subpopulations (sP1, sP2 and sP3), with the proportion of the sP1 population (highly active but non-progressive spermatozoa) being significantly (P<0.05) higher in the HI group. Field fertility was assessed using two calving record datasets. In a smaller database including only bulls evaluated in the present study, there was a significant increase in the calving interval of cows sired with HI bulls. Conversely, in an extended genetic analysis of the ANCRE database, inbreeding only explained a small part of the variation in calving interval, and the results of regression analysis were not significant among bulls. The findings of the present study suggest that high inbreeding levels have a moderate effect on bull semen quality, with an increased percentage of highly active but non-progressive spermatozoa, but only when F values reached a certain threshold. This motility pattern could explain, in part, the higher calving interval produced by inbred bulls under field conditions.
Instituto de Genética Veterinaria
description The present study investigated the effect of inbreeding depression on sperm quality using automated and objective methods and subsequent effects on beef bull field fertility. Individual inbreeding coefficient (F) values and field fertility data were determined using a dataset of AI bulls belonging to the Spanish Retinta Breeders Association (Asociación Nacional de Criadores de Ganado Vacuno Selecto de Raza Retinta (ANCRE)). Animals were clustered in two groups according to the F values as follows: (1) a high inbreeding group (HI; F≥13.5%, mean 16.3); and (2) a non-inbreeding group (NI; F≤0%). In total, 17 different assessments were performed in both experimental groups, including evaluation of sperm morphology, acrosomal and DNA status, sperm plasma membrane integrity and function (hypo-osmotic swelling test), 10 kinetic parameters and the structure of sperm subpopulations. Sperm morphology, acrosomal and DNA status and osmotic tolerance were similar in both groups. Three velocity parameters (curvilinear velocity, straight line velocity and average path velocity) and the amplitude of lateral head displacement were higher in HI (P<0.05). Cluster analysis of kinematic parameters revealed three different sperm subpopulations (sP1, sP2 and sP3), with the proportion of the sP1 population (highly active but non-progressive spermatozoa) being significantly (P<0.05) higher in the HI group. Field fertility was assessed using two calving record datasets. In a smaller database including only bulls evaluated in the present study, there was a significant increase in the calving interval of cows sired with HI bulls. Conversely, in an extended genetic analysis of the ANCRE database, inbreeding only explained a small part of the variation in calving interval, and the results of regression analysis were not significant among bulls. The findings of the present study suggest that high inbreeding levels have a moderate effect on bull semen quality, with an increased percentage of highly active but non-progressive spermatozoa, but only when F values reached a certain threshold. This motility pattern could explain, in part, the higher calving interval produced by inbred bulls under field conditions.
publishDate 2017
dc.date.none.fl_str_mv 2017-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
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info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/101364
url http://sedici.unlp.edu.ar/handle/10915/101364
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://ri.conicet.gov.ar/11336/48139
info:eu-repo/semantics/altIdentifier/url/http://www.publish.csiro.au/rd/RD15324
info:eu-repo/semantics/altIdentifier/issn/1031-3613
info:eu-repo/semantics/altIdentifier/doi/10.1071/RD15324
info:eu-repo/semantics/altIdentifier/hdl/11336/48139
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
712-720
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